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    • 5. 发明申请
    • FIRST TIME RIGHT PLACEMENT OF A DBS LEAD
    • 第一时间放置星巴斯领导
    • US20100036468A1
    • 2010-02-11
    • US12518158
    • 2007-11-16
    • Michael Marcel Jose DecreHubert Cecile Francois Martens
    • Michael Marcel Jose DecreHubert Cecile Francois Martens
    • A61N1/00A61B5/00
    • A61N1/36139A61N1/05A61N1/0529A61N1/0534A61N1/3605A61N1/3606A61N1/36082A61N1/36185
    • The disclosure is directed to a deep brain stimulation (DBS) lead having a distal end for providing therapeutic electrical stimulation to tissue in a stimulation target area of a patient's brain, comprising an array of one or more stimulation elements and sensing elements located at the distal end of the lead; each of the one or more stimulation elements is capable of providing electrical stimulation to the brain tissue in the target area; and each of the one or more sensing elements is capable of detecting electrical signals produced by nerve cells within the brain; wherein after the first implantation of the lead into the brain along a trajectory that is pre-determined by non-surgical procedures, the array of stimulation and sensing elements is capable of facilitating the location of the target area and the determination for each of the stimulation elements of the required stimulation parameters needed to provide the therapeutic stimulation to the brain tissue in the stimulation target area, without requiring any additional implantations of the lead after the first implantation. A stimulation system including the DBS lead and a pulse generator is disclosed. Also disclosed is a method of providing therapeutic DBS to brain tissue using the lead.
    • 本公开涉及具有远端的深部脑刺激(DBS)引线,其用于向患者的大脑的刺激目标区域中的组织提供治疗性电刺激,包括一个或多个刺激元件的阵列和位于远端的感测元件 领先的结束 所述一个或多个刺激元件中的每一个能够向目标区域中的脑组织提供电刺激; 并且所述一个或多个感测元件中的每一个能够检测由脑内的神经细胞产生的电信号; 其中在沿着通过非外科手术预先确定的轨迹将引线首次植入脑中之后,刺激和感测元件的阵列能够促进目标区域的位置和每个刺激的确定 为了在刺激目标区域中的脑组织提供治疗刺激所需的刺激参数的要素,而不需要在第一次植入之后再进行铅的注入。 公开了包括DBS引线和脉冲发生器的刺激系统。 还公开了使用铅向脑组织提供治疗性DBS的方法。
    • 6. 发明授权
    • Connector with a surface with primary and reduntant connection points
    • 连接器与表面具有主要和连接点
    • US08297997B2
    • 2012-10-30
    • US13126361
    • 2009-11-09
    • Hubert Cecile Francois Martens
    • Hubert Cecile Francois Martens
    • H01R13/28
    • A61N1/3752H01R12/75H01R2107/00H01R2201/12
    • A connector (10, 30, 40) is provided for coupling an electronic circuit (11) of an electronic device to sensor and/or actuation elements (12) of the electronic device. The connector (10, 30, 40) comprises at least one connection surface (21) with i connection points (13), the i connection points (13) comprise j primary connection points (13) for coupling the electronic circuit (11) to j corresponding ones of the elements (12), and k redundant connection points (13) for redundantly coupling the electronic circuit (11) to at least one of the elements (12). The primary and the redundant connection points (13) for the at least one of the elements (12) are distributed over the connection surface (21).
    • 提供连接器(10,30,40),用于将电子设备的电子电路(11)耦合到电子设备的传感器和/或致动元件(12)。 连接器(10,30,40)包括具有i个连接点(13)的至少一个连接表面(21),i个连接点(13)包括j个主要连接点(13),用于将电子电路(11)耦合到 j个对应的元件(12)和k个用于将电子电路(11)冗余地耦合到元件(12)中的至少一个的冗余连接点(13)。 元件(12)中的至少一个元件的主要和冗余连接点(13)分布在连接表面(21)上。
    • 7. 发明申请
    • Planning System for Neurostimulation Therapy
    • 神经刺激治疗计划系统
    • US20120109599A1
    • 2012-05-03
    • US13285136
    • 2011-10-31
    • Hubert Cecile Francois Martens
    • Hubert Cecile Francois Martens
    • G06F7/60
    • A61N1/37247A61N1/00
    • A system for planning implantation of a neurostimulation probe is provided. The system comprises an input for receiving anatomical data comprising information regarding a position and an orientation of at least one fiber bundle in a target region, an input for receiving therapeutic information comprising information regarding a stimulation preferability of the at least one fiber bundle, an optimization module for based on the position, the orientation and the stimulation preferability of the at least one fiber bundle calculating at least one optimal position and at least one optimal orientation for implantation of the neurostimulation probe at which optimal position and orientation the probe is capable of generating an electric field gradient substantially parallel to at least one fiber bundle with a high stimulation preferability and/or substantially perpendicular to at least one fiber bundle with a low stimulation preferability and an output for providing the optimal position and orientation.
    • 提供了一种用于规划神经刺激探针植入的系统。 该系统包括用于接收包括关于目标区域中的至少一个纤维束的位置和取向的信息的解剖数据的输入,用于接收包括关于至少一个纤维束的刺激优选性的信息的治疗信息的输入,优化 模块,用于基于所述至少一个纤维束的位置,方向和刺激优选性计算至少一个最佳位置和至少一个用于植入神经刺激探针的最佳取向,其中探针能够产生最佳位置和取向 基本平行于具有高刺激优选性和/或基本垂直于具有低刺激优选性的至少一个纤维束的至少一个纤维束的电场梯度和用于提供最佳位置和取向的输出。
    • 10. 发明申请
    • Optical Disc Having Combined Rom/R Area
    • 结合Rom / R区域的光盘
    • US20080259759A1
    • 2008-10-23
    • US10597565
    • 2005-01-28
    • Hubert Cecile Francois MartensRuud Vlutters
    • Hubert Cecile Francois MartensRuud Vlutters
    • G11B3/74G11B7/00
    • G11B7/24085G11B7/004G11B7/0079G11B7/14G11B7/24038
    • A record carrier has information represented by high density read-only marks in a track. The read-only marks (74,75) are optically readable according to a predefined high-density data format such as CD or DVD via a beam of radiation by first variations of the radiation. The record carrier has a recordable layer (70) for writing recorded marks (72,73) in a recording area of the record carrier, which recording area extends over the track (9) carrying the read-only marks. The recordable layer (70) is arranged to generate second variations of the radiation by a difference between an unrecorded state and a recorded state. A recording device writes recorded marks on top of the read-only marks. A read device recovers the first and second variations, and detects the read-only marks and the recorded marks from a same part of the track.
    • 记录载体具有由轨道中的高密度只读标记表示的信息。 根据预定的高密度数据格式(例如CD或DVD),通过辐射的第一变化经由辐射束,只读标记(74,75)是光学可读的。 记录载体具有用于在记录载体的记录区域中写入记录标记(72,73)的记录层(70),该记录区域在承载只读标记的轨道(9)上延伸。 可记录层(70)被布置成通过未记录状态和记录状态之间的差异来产生辐射的第二变化。 记录装置将记录标记写在只读标记之上。 读取装置恢复第一和第二变化,并且从轨道的相同部分检测只读标记和记录标记。