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1. 发明申请

US20130186392A1 AEROSOL DELIVERY SYSTEM WITH TEMPERATURE-BASED AEROSOL DETECTOR 审中-公开
标题翻译：具有基于温度的气溶胶探测器的航空发送系统
公开(公告)号：US20130186392A1
公开(公告)日：2013-07-25
申请号：US13522814
申请日：2010-12-16
申请人： Jacob Roger Haartsen , Jonathan Stanley Harold Denyer , Michael James Robbert Leppard , Anthony Dyche , Ronald Dekker , Bout Marcelis
发明人： Jacob Roger Haartsen , Jonathan Stanley Harold Denyer , Michael James Robbert Leppard , Anthony Dyche , Ronald Dekker , Bout Marcelis
IPC分类号： A61M16/14 , A61M15/00 , A61M11/04
CPC分类号： A61M16/14 , A61M11/04 , A61M15/0065 , A61M15/008 , A61M15/0085 , A61M2205/3368 , A61M2205/44 , A61M2205/52 , A61M2205/581 , A61M2205/583
摘要： An aerosol delivery system (e.g., MDI or nebulizer for delivering aerosolized medication to a patient) includes a temperature sensor (10) in an aerosol output pathway of the system. A controller (600) determines that an aerosol generator of the system has released aerosol when the sensor senses a predetermined temperature change in the pathway. The temperature sensor may also comprise a thermal flow sensor that includes a heater and upstream and downstream temperature sensors. The controller compares the upstream and downstream temperatures to determine the presence, direction, and/or magnitude of fluid flow in the pathway. The controller may use the aerosol detection and/or flow detection to monitor compliance with desired use of the system and/or provide real-time instructions to a user for proper use of the system. The controller may record the aerosolization and flow data for later analysis.
摘要翻译：气溶胶递送系统（例如，用于将雾化的药物递送给患者的MDI或雾化器）包括在系统的气溶胶输出路径中的温度传感器（10）。当传感器感测到路径中的预定温度变化时，控制器（600）确定系统的气溶胶发生器已经释放气溶胶。温度传感器还可以包括热流传感器，其包括加热器和上游和下游温度传感器。控制器比较上游和下游温度，以确定通道中流体流动的存在，方向和/或幅度。控制器可以使用气溶胶检测和/或流量检测来监测系统的期望使用的符合性和/或向用户提供实时指令以正确使用该系统。控制器可以记录雾化和流数据供以后分析。

2. 发明申请

US20120291779A1 FLOW SENSOR AND AEROSOL DELIVERY DEVICE 审中-公开
标题翻译：流量传感器和航空运输装置
公开(公告)号：US20120291779A1
公开(公告)日：2012-11-22
申请号：US13522798
申请日：2010-12-16
申请人： Jacob Roger Haartsen , Jonathan Stanley Harold Denyer , Michael James Robbert Leppard , Anthony Dyche , Ronald Dekker , Bout Marcelis
发明人： Jacob Roger Haartsen , Jonathan Stanley Harold Denyer , Michael James Robbert Leppard , Anthony Dyche , Ronald Dekker , Bout Marcelis
IPC分类号： A61M15/00
CPC分类号： G01F1/684 , A61M15/0065
摘要： An aerosol delivery system (e.g., MDI or nebulizer for delivering aerosolized medication to a patient) includes a temperature sensor in an aerosol output pathway of the system. A controller determines that an aerosol generator of the system has released aerosol when the sensor senses a predetermined temperature change in the pathway. The temperature sensor may also comprise a thermal flow sensor that includes a heater and upstream and downstream temperature sensors. The controller compares the upstream and downstream temperatures to determine the presence, direction, and/or magnitude of fluid flow in the pathway. The controller may use the aerosol detection and/or flow detection to monitor compliance with desired use of the system and/or provide real-time instructions to a user for proper use of the system. The controller may record the aerosolization and flow data for later analysis.
摘要翻译：气雾剂输送系统（例如，用于将雾化的药物递送到患者的MDI或雾化器）包括系统的气溶胶输出路径中的温度传感器。当传感器感测到路径中的预定温度变化时，控制器确定系统的气溶胶发生器已经释放气溶胶。温度传感器还可以包括热流传感器，其包括加热器和上游和下游温度传感器。控制器比较上游和下游温度，以确定通道中流体流动的存在，方向和/或幅度。控制器可以使用气溶胶检测和/或流量检测来监测系统的期望使用的符合性和/或向用户提供实时指令以正确使用该系统。控制器可以记录雾化和流数据供以后分析。

3. 发明申请

US20120285236A1 METHOD OF USING A TEMPERATURE-BASED AEROSOL DETECTOR 审中-公开
标题翻译：使用基于温度的气溶胶检测器的方法
公开(公告)号：US20120285236A1
公开(公告)日：2012-11-15
申请号：US13574117
申请日：2010-12-14
申请人： Jacob Roger Haartsen , Jonathan Stanley Harold Denyer , Michael James Robbert Leppard , Anthony Dyche , Ronald Dekker , Bout Marcelis
发明人： Jacob Roger Haartsen , Jonathan Stanley Harold Denyer , Michael James Robbert Leppard , Anthony Dyche , Ronald Dekker , Bout Marcelis
IPC分类号： G01F1/68
CPC分类号： A61M15/0065 , A61M11/005 , A61M11/06 , A61M15/008 , A61M15/0086 , A61M15/009 , A61M2205/3368 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/583 , G01F1/684 , G01F1/6888
摘要： An aerosol delivery system (e.g., MDI or nebulizer for delivering aerosolized medication to a patient) includes a temperature sensor in an aerosol output pathway of the system. A controller determines that an aerosol generator of the system has released aerosol when the sensor senses a predetermined temperature change in the pathway. The temperature sensor may also comprise a thermal flow sensor that includes a heater and upstream and downstream temperature sensors. The controller compares the upstream and downstream temperatures to determine the presence, direction, and/or magnitude of fluid flow in the pathway. The controller may use the aerosol detection and/or flow detection to monitor compliance with desired use of the system and/or provide real-time instructions to a user for proper use of the system. The controller may record the aerosolization and flow data for later analysis.
摘要翻译：气雾剂输送系统（例如，用于将雾化的药物递送到患者的MDI或雾化器）包括系统的气溶胶输出路径中的温度传感器。当传感器感测到路径中的预定温度变化时，控制器确定系统的气溶胶发生器已经释放气溶胶。温度传感器还可以包括热流传感器，其包括加热器和上游和下游温度传感器。控制器比较上游和下游温度，以确定通道中流体流动的存在，方向和/或幅度。控制器可以使用气溶胶检测和/或流量检测来监测系统的期望使用的符合性和/或向用户提供实时指令以正确使用该系统。控制器可以记录雾化和流数据供以后分析。

4. 发明申请

US20120209069A1 COLLISION AVOIDANCE AND DETECTION USING DISTANCE SENSORS 审中-公开
标题翻译：使用距离传感器的碰撞避免和检测
公开(公告)号：US20120209069A1
公开(公告)日：2012-08-16
申请号：US13502412
申请日：2010-10-04
申请人： Aleksandra Popovic , Mareike Klee , Bout Marcelis , Christianus Martinus Van Heesch
发明人： Aleksandra Popovic , Mareike Klee , Bout Marcelis , Christianus Martinus Van Heesch
IPC分类号： A61B1/00 , A61B1/04
CPC分类号： A61B5/065 , A61B1/00147 , A61B1/00149 , A61B1/00193 , A61B34/30 , A61B2034/105 , A61B2034/301 , A61B2090/062 , A61B2090/08021 , A61B2090/3614 , A61B2090/367 , A61B2090/3784 , A61B2090/506 , G06T7/579 , G06T2207/10068 , G06T2207/30004
摘要： An endoscopic method involves an advancement of an endoscope (20) as controlled by an endoscopic robot (31) to a target location within an anatomical region of a body, and a generation of a plurality of monocular endoscopic images (80) of the anatomical region as the endoscope (20) is advanced to the target location by the endoscopic robot (31). For avoiding or detecting a collision of the endoscope (20) with and object within monocular endoscopic images (80) (e.g., a ligament within monocular endoscopic images of a knee), the method further involves a generation of distance measurements of the endoscope (20) from the object as the endoscope (20) is advanced to the target location by the endoscopic robot (31), and a reconstruction of a three-dimensional image of a surface of the object within the monocular endoscopic images (80) as a function of the distance measurements (81).
摘要翻译：内窥镜方法包括将内窥镜机器人（31）控制的内窥镜（20）推进到身体的解剖区域内的目标位置，以及生成解剖区域的多个单目内窥镜图像（80）当内窥镜（20）通过内窥镜机器人（31）前进到目标位置时。为了避免或检测内窥镜（20）与单眼内窥镜图像（80）（例如膝盖的单眼内窥镜图像内的韧带）的对象的碰撞，该方法还包括生成内窥镜（20）的距离测量）由内窥镜（20）通过内窥镜机器人（31）前进到目标位置，并且将单眼内窥镜图像（80）内的物体的表面的三维图像重建为功能的距离测量（81）。

5. 发明申请

US20120085934A1 POSITION DETERMINING SYSTEM 审中-公开
标题翻译：位置决定系统
公开(公告)号：US20120085934A1
公开(公告)日：2012-04-12
申请号：US13378068
申请日：2010-06-17
申请人： Bout Marcelis , Christianus Martinus Van Heesch , Mareike Klee , Drazenko Babic
发明人： Bout Marcelis , Christianus Martinus Van Heesch , Mareike Klee , Drazenko Babic
IPC分类号： G01N23/00 , G01S15/06 , G01N21/00
CPC分类号： G01S5/18 , G01S15/876 , G01S2013/468 , G01S2015/465
摘要： The invention relates to position determining system (201) for determining a position of an object (2). A first position detection unit (205) detects a first position of the object (2) based on radiation transferred between the object (2) and transfer positions being known relative to a reference position by a sending and receiving unit (203, 214, 216, 217). A second position detection unit (35) detects a second position based on an acceleration of the object (2) and the determined first position, wherein an output unit (12) outputs at least one of the first position and the second position. If the transfer of radiation is interrupted, the second position can be output by the output unit. Moreover, the first position can be used as an initial value for determining the second position or to update the second position. This improves the quality of determining the position of the object.
摘要翻译：本发明涉及一种用于确定物体（2）的位置的位置确定系统（201）。第一位置检测单元（205）基于通过发送和接收单元（203,214,216）在对象（2）和相对于参考位置已知的传送位置之间传送的辐射来检测对象（2）的第一位置，217）。第二位置检测单元（35）基于物体（2）的加速度和确定的第一位置来检测第二位置，其中输出单元（12）输出第一位置和第二位置中的至少一个。如果辐射传输中断，则第二位置可以由输出单元输出。此外，第一位置可以用作用于确定第二位置的初始值或者更新第二位置。这提高了确定对象位置的质量。

6. 发明申请

US20110245713A1 MEDICAL DEVICE COMPRISING A PROBE FOR MEASURING TEMPERATURE DATA IN A PATIENT'S TISSUE 审中-公开
标题翻译：包含用于测量患者组织中的温度数据的探针的医疗装置
公开(公告)号：US20110245713A1
公开(公告)日：2011-10-06
申请号：US13127046
申请日：2009-11-09
申请人： Judith Margreet Rensen , Jaap Haartsen , Mareike Klee , Drazenko Babic , Bernardus Hendrikus Wilhelmus Hendriks , Christianus Martinus Van Heesch , Bout Marcelis
发明人： Judith Margreet Rensen , Jaap Haartsen , Mareike Klee , Drazenko Babic , Bernardus Hendrikus Wilhelmus Hendriks , Christianus Martinus Van Heesch , Bout Marcelis
IPC分类号： A61B5/01
CPC分类号： G01K13/002 , A61B5/01 , A61B2562/0271 , G01K3/14 , G01K7/02
摘要： A medical device comprising a probe for measurement temperature data of tissue within a patient's body is proposed. The probe (2) comprises a flexible substrate (3) attached to a medical device core (5), the flexible substrate (3) comprising one or more thermopiles (7) and may furthermore comprise resistors for measuring an absolute temperature and heat sources for locally applying heat. The thermopiles can be processed directly on a flexible polymer carrier or, alternatively, on a silicon substrate and transferred to a flexible carrier (3) enabling both, a highly flexible substrate (3) and very small structural dimensions for the thermopiles (7) and, possibly, the resistors and heat sources. Accordingly, measurement of temperature gradients of tissue being in contact to the medical device may be performed at high resolution allowing reliable detection of temperature anomalies e.g. due to malign tissue.
摘要翻译：提出了包括用于测量患者身体内的组织的温度数据的探针的医疗装置。探针（2）包括附接到医疗器件芯（5）的柔性衬底（3），柔性衬底（3）包括一个或多个热电堆（7），并且还可以包括用于测量绝对温度的电阻器和用于局部施加热量。可以将热电堆直接加工在柔性聚合物载体上，或者在硅衬底上进行处理，并转移到柔性载体（3）上，从而使高弹性基底（3）和热电堆（7）的非常小的结构尺寸和，可能是电阻和热源。因此，可以以高分辨率执行与医疗装置接触的组织的温度梯度的测量，从而可以可靠地检测温度异常。由于恶性组织。

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