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    • 7. 发明授权
    • 5H-pyrrolo(3',4':5,6)(1,4)dithiin
o(2,3-C)(1,2,5)thiadiazole-5,7(6H)-dione, compositions containing them
and their use as antimicrobial and marine antifouling agents
    • 5H-吡咯并(3',4':5,6)(1,4)二硫基(2,3-C)(1,2,5)噻二唑-5,7(6H) - 二酮,含有它们的组合物及其 用作抗菌和海洋防污剂
    • US5633219A
    • 1997-05-27
    • US676618
    • 1996-07-10
    • Ravi B. ShankarR. Garth PewsDuane R. Romer
    • Ravi B. ShankarR. Garth PewsDuane R. Romer
    • A01N43/90C07D513/14A01N43/82A61K31/41C07D271/12
    • C07D513/14A01N43/90
    • Various 5H-pyrrolo(3',4':5,6)(1,4) dithiino-(2,3-C)(1,2,5)thiadiazole-5,7(6H)-diones corresponding to the formula ##STR1## wherein R represents --H, benzyl, phenethyl, a C.sub.1 -C.sub.10 straight or branched chain alkyl radical, a C.sub.3 -C.sub.10 cycloalkyl radical, a C.sub.1 -C.sub.10 straight or branched chain alkoxy radical, a C.sub.3 -C.sub.10 -cycloalkoxy, an ester of the formula --CH.sub.2 CH.sub.2 O--C(O)--R.sup.1, wherein R.sup.1 represents a C.sub.1 -C.sub.6 straight or branched chain alkyl radical or a C.sub.3 -C.sub.6 cycloalkyl radical or R represents phenyl substituted with from 0-5 halo, C.sub.1 -C.sub.6 straight or branched chain alkyl, cyano, nitro groups, or an ester of the formula --OC(O)--R.sup.1, wherein R.sup.1 represents a C.sub.1 -C.sub.6 straight or branched chain alkyl radical or a C.sub.3 -C.sub.6 cycloalkyl radical or an amide of the formula --C(O)--N(R.sup.2).sub.x, wherein each R.sup.2 independently represents a C.sub.1 -C.sub.6 straight or branched chain alkyl radical or a C.sub.3 -C.sub.6 cycloalkyl radical are disclosed. These compounds have been found to exhibit antimicrobial and marine antifouling activity in industrial and commercial applications and compositions containing these compounds are so employed.
    • 对应于式(I)的各种5H-吡咯并(3',4':5,6)(1,4)二硫基 - (2,3-C)(1,2,5)噻二唑-5,7(6H) (I)其中R表示-H,苄基,苯乙基,C1-C10直链或支链烷基,C3-C10环烷基,C1-C10直链或支链烷氧基,C3-C10- 环烷氧基,式-CH 2 CH 2 O-C(O)-R 1的酯,其中R 1表示C 1 -C 6直链或支链烷基或C 3 -C 6环烷基,或R表示被0-5个卤素取代的苯基,C1 -C6直链或支链烷基,氰基,硝基或式-OC(O)-R1的酯,其中R1表示C1-C6直链或支链烷基或C3-C6环烷基或酰胺 的式-C(O)-N(R 2)x,其中每个R 2独立地表示C 1 -C 6直链或支链烷基或C 3 -C 6环烷基。 已经发现这些化合物在工业和商业应用中表现出抗微生物和海洋防污性,并且使用含有这些化合物的组合物。