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1. 发明授权

US5733745A Bovine heat shock promoter and uses thereof 失效
公开(公告)号：US5733745A
公开(公告)日：1998-03-31
申请号：US599825
申请日：1996-02-12
申请人： Jacek Kowalski , Scott Gilbert , Timothy J. Zamb
发明人： Jacek Kowalski , Scott Gilbert , Timothy J. Zamb
IPC分类号： C12N15/09 , A61K39/00 , C07K14/03 , C12N1/21 , C12N5/10 , C12N15/38 , C12N15/40 , C12N15/85 , C12P21/00 , C12N15/11
CPC分类号： C07K14/005 , C12N15/85 , A61K39/00 , C07K2319/02 , C12N2710/16722 , C12N2830/002 , C12N2830/85
摘要： A novel expression system using the heat-inducible bovine hsp70A promoter and associated cis-acting elements is disclosed. The system provides for the continuous production of a highly pure, authentic protein, substantially free of infectious viral and cellular protein contaminants.

2. 发明授权

US5981224A Bovine heat shock promoter and uses thereof 失效
标题翻译：牛热休克启动子及其用途
公开(公告)号：US5981224A
公开(公告)日：1999-11-09
申请号：US48488
申请日：1998-03-26
申请人： Jacek Kowalski , Scott Gilbert , Timothy J. Zamb
发明人： Jacek Kowalski , Scott Gilbert , Timothy J. Zamb
IPC分类号： C12N15/09 , A61K39/00 , C07K14/03 , C12N1/21 , C12N5/10 , C12N15/38 , C12N15/40 , C12N15/85 , C12P21/00 , C12N15/11
CPC分类号： C07K14/005 , C12N15/85 , A61K39/00 , C07K2319/02 , C12N2710/16722 , C12N2830/002 , C12N2830/85
摘要： A novel expression system using the heat-inducible bovine hsp70A promoter and associated cis-acting elements is disclosed. The system provides for the continuous production of a highly pure, authentic protein, substantially free of infectious viral and cellular protein contaminants.
摘要翻译：公开了一种使用热诱导型牛hsp70A启动子和相关顺式作用元件的新型表达系统。该系统提供连续生产基本上不含感染性病毒和细胞蛋白质污染物的高纯度，可靠的蛋白质。

3. 发明授权

US5521084A Bovine heat shock promoter and uses thereof 失效
公开(公告)号：US5521084A
公开(公告)日：1996-05-28
申请号：US975719
申请日：1992-11-10
申请人： Jacek Kowalski , Scott Gilbert , Timothy J. Zamb
发明人： Jacek Kowalski , Scott Gilbert , Timothy J. Zamb
IPC分类号： C12N15/09 , A61K39/00 , C07K14/03 , C12N1/21 , C12N5/10 , C12N15/38 , C12N15/40 , C12N15/85 , C12P21/00 , C12N15/11
CPC分类号： C07K14/005 , C12N15/85 , A61K39/00 , C07K2319/02 , C12N2710/16722 , C12N2830/002 , C12N2830/85
摘要： A novel expression system using the heat-inducible bovine hsp70A promoter and associated cis-acting elements is disclosed. The system provides for the continuous production of a highly pure, authentic protein, substantially free of infectious viral and cellular protein contaminants.

4. 发明申请

US20070052139A1 Method for making a needle-free jet injection drug delivery device 有权
标题翻译：无针喷射药物输送装置的制造方法
公开(公告)号：US20070052139A1
公开(公告)日：2007-03-08
申请号：US11200971
申请日：2005-08-10
申请人： Scott Gilbert
发明人： Scott Gilbert
IPC分类号： B29C35/08
CPC分类号： A61M5/30 , A61M5/19 , A61M5/2046 , A61M5/2053 , A61M5/3007 , A61M5/31511 , A61M2205/587 , A61M2205/59 , A61M2210/0612 , A61M2210/0618
摘要： A method for making a jet injection drug delivery device wherein the drug delivery device has at least one drug reservoir and at least one injection nozzle includes the steps of: identifying a drug desired to be delivered; identifying a volume of the drug desired to be delivered; establishing a reservoir diameter for the at least one drug reservoir; establishing a nozzle diameter for the at least one injection nozzle; identifying a tissue model for delivery of the drug; identifying a penetration depth in the tissue model for the delivery of the drug; and injecting the drug into the tissue model under variable pressure until the desired penetration depth is achieved. The method also includes identifying an optimal pressure range for the drug delivery device that achieves the desired penetration depth.
摘要翻译：一种制备喷射药物输送装置的方法，其中所述药物递送装置具有至少一个药物储存器和至少一个注射喷嘴，包括以下步骤：鉴定期望被输送的药物; 确定期望送达的药物的体积; 建立所述至少一个药物储存器的储存器直径; 为所述至少一个喷嘴建立喷嘴直径; 识别用于递送药物的组织模型; 识别用于递送药物的组织模型中的穿透深度; 并在可变压力下将药物注入组织模型中，直到达到期望的穿透深度。该方法还包括识别实现期望的穿透深度的药物递送装置的最佳压力范围。

5. 发明授权

US06683608B2 Seaming polygonal projections from subhemispherical imagery 有权
标题翻译：从半像素图像缝合多边形投影
公开(公告)号：US06683608B2
公开(公告)日：2004-01-27
申请号：US09970418
申请日：2001-10-03
申请人： Stuart J. Golin , Scott Gilbert , Thomas Baker
发明人： Stuart J. Golin , Scott Gilbert , Thomas Baker
IPC分类号： G06T1500
CPC分类号： G06T15/20
摘要： A method and apparatus for generating views of an environment with proper perspective and parallax. This invention captures panoramic views at many points in the environment, preferably by using fisheye lenses with subhemispherical fields of views to yield overlapping fisheye images that are seemed together, and stores them as planar polygons, which have been extended to include imagery occluded at their viewing position but visible at nearby points. Three-dimensional information on the environmental source of these polygons is determined and stored, enabling the playback system to simulate parallax as well as to produce stereographic images. Given a location and orientation in the environment, the playback system finds a nearby capture point and translates the polygons at that point to the specified location, producing an image. It then rotates that image to the desired orientation which it then displays.
摘要翻译：一种用于产生具有适当透视和视差的环境视图的方法和装置。本发明在环境中的许多点捕获全景，优选地通过使用具有亚视场视野的鱼眼镜头产生似乎在一起的重叠鱼眼图像，并且将它们存储为平面多边形，其被扩展为包括在其观看时封闭的图像位置，但在附近点可见。确定并存储关于这些多边形的环境源的三维信息，使得播放系统能够模拟视差以及产生立体图像。给定环境中的位置和方位，播放系统找到附近的捕获点，并将该点处的多边形转换到指定的位置，从而产生图像。然后将该图像旋转到所需的方向，然后显示它。

6. 发明申请

US20070055214A1 Method for delivering drugs to tissue under microjet propulsion 有权
标题翻译：在微型喷气推进下向药物输送药物的方法
公开(公告)号：US20070055214A1
公开(公告)日：2007-03-08
申请号：US11200749
申请日：2005-08-10
申请人： Scott Gilbert
发明人： Scott Gilbert
IPC分类号： A61M31/00
CPC分类号： A61M5/30 , A61M5/19 , A61M5/2046 , A61M5/2053 , A61M5/3007 , A61M5/31511 , A61M2205/587 , A61M2205/59 , A61M2210/0612 , A61M2210/0618
摘要： A method for delivering a drug into tissue includes the steps of: providing a drug delivery device having at least one nozzle and a drug contained in a portion of the device; identifying a site for delivery of the drug in or on tissue; placing a portion of the device on or near the site; and delivering the drug into the tissue at the site through at least one nozzle of the device under microjet propulsion.
摘要翻译：用于将药物递送到组织中的方法包括以下步骤：提供药物递送装置，其具有包含在装置的一部分中的至少一个喷嘴和药物; 识别在组织内或组织上递送药物的部位; 将设备的一部分放置在站点上或附近; 以及通过所述装置的至少一个喷嘴在所述微喷射推进下将所述药物输送到所述部位的组织中。

7. 发明申请

US20070055199A1 Drug delivery device for buccal and aural applications and other areas of the body difficult to access 审中-公开
标题翻译：用于口腔和听觉应用的药物输送装置等身体难以进入的区域
公开(公告)号：US20070055199A1
公开(公告)日：2007-03-08
申请号：US11200772
申请日：2005-08-10
申请人： Scott Gilbert
发明人： Scott Gilbert
IPC分类号： A61M5/30
CPC分类号： A61M5/30 , A61M5/19 , A61M5/2046 , A61M5/2053 , A61M5/3007 , A61M5/31511 , A61M2205/587 , A61M2205/59 , A61M2210/0612 , A61M2210/0618
摘要： A device for delivering a drug includes a delivery tube wherein the delivery tube has a pressure chamber therein and at least one nozzle at a distal end of the delivery tube and in fluid communication with the pressure chamber. A source of drug is adjacent the at least one nozzle and a handle is located at a proximal end of the delivery tube. An energy source is located in the handle for providing a driving pressure of up to about 2,000 psi within the delivery tube for driving the drug through the at least one nozzle and out of the delivery tube. The delivery device is particularly useful for delivering drug under microjet propulsion to the mouth, ear and other areas of the body that are difficult to access.
摘要翻译：用于递送药物的装置包括输送管，其中输送管在其中具有压力室，并且在输送管的远端处具有至少一个喷嘴并与压力室流体连通。药物源与至少一个喷嘴相邻，手柄位于输送管的近端。能量源位于手柄中，用于在输送管内提供高达约2,000psi的驱动压力，用于驱动药物通过至少一个喷嘴并从输送管中排出。输送装置特别适用于在微型喷气推进下将药物输送到难以进入的身体的口，耳和其他区域。

8. 发明申请

US20060288567A1 SACRIFICIAL COMPONENT 审中-公开
公开(公告)号：US20060288567A1
公开(公告)日：2006-12-28
申请号：US11468231
申请日：2006-08-29
申请人： Shawn Lloyd , John Oldendorf , Michael Kochanowski , Scott Gilbert
发明人： Shawn Lloyd , John Oldendorf , Michael Kochanowski , Scott Gilbert
IPC分类号： H01H11/00 , H05K3/30 , H05K3/00
CPC分类号： H01L23/62 , H01L2224/16 , H01L2924/15311 , H01L2924/19106 , H05K1/141 , H05K3/3436 , H05K2201/10181 , H05K2201/10204 , H05K2201/2036 , H05K2203/1572 , Y10T29/49105 , Y10T29/4913 , Y10T29/49147 , Y10T29/49149
摘要： A device includes a substrate. The substrate further includes a first major surface including a plurality of lands, and a second major surface. At least one component is attached to at least some of the plurality of pads on the first major surface. At least one sacrificial component is attached to the first major surface. The at least one component has a first height with respect to the first major surface, and the at least one sacrificial component has a second height with respect to the first major surface. The second height is greater than the first height. The sacrificial component includes a fuse.
摘要翻译：一种器件包括衬底。衬底还包括包括多个焊盘的第一主表面和第二主表面。至少一个部件附接到第一主表面上的多个焊盘中的至少一些。至少一个牺牲部件附接到第一主表面。所述至少一个部件相对于所述第一主表面具有第一高度，并且所述至少一个牺牲部件相对于所述第一主表面具有第二高度。第二个高度大于第一个高度。牺牲部件包括保险丝。

9. 发明授权

US6031540A Method and apparatus for simulating movement in multidimensional space with polygonal projections from subhemispherical imagery 失效
标题翻译：用于模拟多维空间中运动的方法和装置，具有来自亚像差图像的多边形投影
公开(公告)号：US6031540A
公开(公告)日：2000-02-29
申请号：US980503
申请日：1997-12-01
申请人： Stuart J. Golin , Scott Gilbert , Thomas Baker
发明人： Stuart J. Golin , Scott Gilbert , Thomas Baker
IPC分类号： G06T15/20 , G06F15/00
CPC分类号： G06T15/20
摘要： A method and apparatus for generating views of an environment with proper perspective and parallax. This invention captures panoramic views at many points in the environment, preferably by using fisheye lenses with subhemispherical fields of views to yield overlapping fisheye images that are seemed together, and stores them as planar polygons, which have been extended to include imagery occluded at their viewing position but visible at nearby points. Three-dimensional information on the environmental source of these polygons is determined and stored, enabling the playback system to simulate parallax as well as to produce stereographic images. Given a location and orientation in the environment, the playback system finds a nearby capture point and translates the polygons at that point to the specified location, producing an image. It then rotates that image to the desired orientation which it then displays.
摘要翻译：一种用于产生具有适当透视和视差的环境视图的方法和装置。本发明在环境中的许多点捕获全景，优选地通过使用具有亚视场视野的鱼眼镜头产生似乎在一起的重叠鱼眼图像，并且将它们存储为平面多边形，其被扩展为包括在其观看时封闭的图像位置，但在附近点可见。确定并存储关于这些多边形的环境源的三维信息，使得播放系统能够模拟视差以及产生立体图像。给定环境中的位置和方位，播放系统找到附近的捕获点，并将该点处的多边形转换到指定的位置，从而产生图像。然后将该图像旋转到所需的方向，然后显示它。

10. 发明授权

US07620909B2 Interactive image seamer for panoramic images 有权
标题翻译：用于全景图像的交互式图像封隔器
公开(公告)号：US07620909B2
公开(公告)日：2009-11-17
申请号：US10789508
申请日：2004-02-26
申请人： Michael C. Park , Scott Gilbert
发明人： Michael C. Park , Scott Gilbert
IPC分类号： G06F3/048
CPC分类号： H04N5/23238 , H04N5/232 , H04N5/77 , H04N7/181 , H04N9/8047 , H04N9/806 , H04N9/8211 , H04N9/8227 , H04N9/8233
摘要： An interactive computer program for seaming a number of images into a panorama. Various parameters which affect how the images are seamed can be changed interactively. Parameters such as position, orientation, focal length, which image will be visible where images overlap, and the opacity curve can be changed. The result of any change is immediately visible. A user can move the control points, thereby “morphing” or distorting the contribution to the panorama of an image. Each pixel is assigned an “alpha” value which indicates the opacity value of that pixel in an area where images overlap. Alpha values can be changed according to a pre-established curve. The original images are not changed. Instead, only the transform between the original images and the final panorama is changed.
摘要翻译：用于将多个图像接合到全景中的交互式计算机程序。可以交互地改变影响图像被缝合的各种参数。诸如位置，方向，焦距，图像在图像重叠时可见的参数和不透明度曲线等参数都可以改变。任何更改的结果立即可见。用户可以移动控制点，从而“变形”或扭曲对图像全景的贡献。每个像素被分配一个“alpha”值，它表示图像重叠的区域中该像素的不透明度值。 Alpha值可以根据预先建立的曲线进行更改。原始图像未更改。相反，只有原始图像和最终全景图之间的变换才会改变。

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