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1. 发明申请

US20110167090A1 SYSTEMS AND METHODS FOR STORING AND RETRIEVING DATA 有权
标题翻译：用于存储和检索数据的系统和方法
公开(公告)号：US20110167090A1
公开(公告)日：2011-07-07
申请号：US12986086
申请日：2011-01-06
申请人： Ivan W. Pulleyn , Stuart Bailey
发明人： Ivan W. Pulleyn , Stuart Bailey
IPC分类号： G06F17/30
CPC分类号： H04L61/1511 , G06F17/30958 , H04L29/12066 , H04L29/12132 , H04L61/1552
摘要： Storing data is disclosed. A range or addresses is received and the range of addresses is stored in a bulk object. Retrieving data is disclosed. A request to access data associated with an address within a range of addresses is received. A response is derived based at least in part on a bulk object.
摘要翻译：披露数据的存储。接收到范围或地址，并将地址范围存储在批量对象中。公开了检索数据。接收到访问与地址范围内的地址相关联的数据的请求。至少部分地基于大量对象导出响应。

2. 发明授权

US09065851B2 Systems and methods for storing and retrieving data 有权
标题翻译：用于存储和检索数据的系统和方法
公开(公告)号：US09065851B2
公开(公告)日：2015-06-23
申请号：US12986086
申请日：2011-01-06
申请人： Ivan W. Pulleyn , Stuart Bailey
发明人： Ivan W. Pulleyn , Stuart Bailey
IPC分类号： G06F7/00 , G06F17/30 , H04L29/12
CPC分类号： H04L61/1511 , G06F17/30958 , H04L29/12066 , H04L29/12132 , H04L61/1552
摘要： Storing data is disclosed. A range or addresses is received and the range of addresses is stored in a bulk object. Retrieving data is disclosed. A request to access data associated with an address within a range of addresses is received. A response is derived based at least in part on a bulk object.
摘要翻译：披露数据的存储。接收到范围或地址，并将地址范围存储在批量对象中。公开了检索数据。接收到访问与地址范围内的地址相关联的数据的请求。至少部分地基于大量对象导出响应。

3. 发明授权

US07889676B1 Systems and methods for storing and retrieving data 有权
标题翻译：用于存储和检索数据的系统和方法
公开(公告)号：US07889676B1
公开(公告)日：2011-02-15
申请号：US11404375
申请日：2006-04-13
申请人： Ivan W. Pulleyn , Stuart Bailey
发明人： Ivan W. Pulleyn , Stuart Bailey
IPC分类号： H04L12/28
CPC分类号： H04L61/1511 , G06F17/30958 , H04L29/12066 , H04L29/12132 , H04L61/1552
摘要： Systems and methods for storing and retrieving data are disclosed. An example method includes the steps of receiving a range of addresses, storing the range of addresses in a bulk object in a database for storing information associated with addresses. In some embodiments the storing includes inserting the bulk object into an index, the index being a structure used to access objects in the database. In some embodiments, the method may further include receiving a request to retrieve the addresses stored and generating a response to the response, where the response is at least in part based on the bulk object.
摘要翻译：公开了用于存储和检索数据的系统和方法。示例性方法包括以下步骤：接收地址范围，将批量对象中的地址范围存储在用于存储与地址相关联的信息的数据库中。在一些实施例中，存储包括将批量对象插入到索引中，索引是用于访问数据库中的对象的结构。在一些实施例中，该方法还可以包括：接收请求以检索所存储的地址并产生响应的响应，其中所述响应至少部分地基于所述批量对象。

4. 发明授权

US08533169B1 Transactional replication 有权
标题翻译：事务复制
公开(公告)号：US08533169B1
公开(公告)日：2013-09-10
申请号：US11232418
申请日：2005-09-21
申请人： Stuart Bailey , Ivan W. Pulleyn , Srinath Gutti
发明人： Stuart Bailey , Ivan W. Pulleyn , Srinath Gutti
IPC分类号： G06F17/00 , G06F17/30
CPC分类号： G06F17/30309 , G06F17/30575 , G06F17/30923
摘要： Writing data in a distributed database having a plurality of nodes is disclosed. Writing includes receiving a write request at a node, wherein the write request is associated with one or more operations to define an atomic transaction and performing the atomic transaction based on the request. The atomic transaction includes writing to a first version of the database in the node and writing to an entity representative of a state of the first version of the database.
摘要翻译：公开了具有多个节点的分布式数据库中的数据写入。写入包括在节点处接收写请求，其中所述写请求与一个或多个操作相关联以定义原子事务并且基于所述请求执行所述原子事务。原子事务包括写入节点中的数据库的第一版本并写入表示数据库的第一版本的状态的实体。

5. 发明授权

US07531549B2 Phenylalanine enamide derivatives 失效
标题翻译：苯丙氨酸烯酰胺衍生物
公开(公告)号：US07531549B2
公开(公告)日：2009-05-12
申请号：US11533117
申请日：2006-09-19
申请人： Stephen Brand , Stuart Bailey , Julien A. Brown , James A. Johnson , John R. Porter , John C. Head
发明人： Stephen Brand , Stuart Bailey , Julien A. Brown , James A. Johnson , John R. Porter , John C. Head
IPC分类号： C07D211/82 , C07D471/10 , A61K31/4747
CPC分类号： C07D213/81 , C04B35/632 , C07C229/10 , C07C229/46 , C07C233/81 , C07C233/82 , C07C323/30 , C07C2601/04 , C07C2603/94 , C07C2603/96 , C07D213/79 , C07D213/89 , C07D311/96 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D471/04
摘要： Phenylalanine enamide derivatives of formula (1) are described: wherein R1 is a group Ar1L2Ar2Alk- in which: Ar1 is an optionally substituted aromatic or heteroaromatic group; L2 is a covalent bond or a linker atom or group; Ar2 is an optionally substituted arylene or heteroarylene group; and Alk is a chain —CH2—CH(R)—, —CH═C(R)— or in which R is a carboxylic acid (—CO2H) or a derivative or biostere thereof; X is an —O— or —S— atom or —N(R2)— group in which: Rx, Ry and Rz which may be the same or different is each a hydrogen atom or an optional substituent; or Rz is an atom or group as previously defined and Rx and Ry are joined together to form an optionally substituted spiro linked cycloaliphatic or heterocycloaliphatic group; and the salts, solvates, hydrates and N-oxides thereof. The compounds are able to inhibit the binding of integrins to their ligands and are of use in the prophylaxis and treatment of immuno or inflammatory disorders or disorders involving the inappropriate growth or migration of cells.
摘要翻译：描述式（1）的苯丙氨酸烯酰胺衍生物：其中R1是Ar1L2Ar2Alk-基团，其中：Ar1是任选取代的芳族或杂芳族基团; L2是共价键或连接体原子或基团; Ar 2是任选取代的亚芳基或亚杂芳基; 并且Alk是一条链<？in-line-formula description =“In-line Formulas”end =“lead”？> - CH2-CH（R） - ，-CH-C（R） - 或<？ -formulae description =“In-line Formulas”end =“tail”？>其中R是羧酸（-CO 2 H）或其衍生物或生物试剂; X是-O-或-S-原子或-N（R 2） - 基团，其中：可以相同或不同的R x，R y和R z各自为氢原子或任选的取代基; 或R z是如先前定义的原子或基团，并且R x和R y连接在一起以形成任选取代的螺环连接的脂环族或杂环脂族基团; 及其盐，溶剂合物，水合物和N-氧化物。该化合物能够抑制整联蛋白与其配体的结合，并且可用于预防和治疗涉及细胞不适当生长或迁移的免疫或炎性疾病或病症。

6. 发明授权

US06878718B2 Phenylalanine enamide derivatives 失效
标题翻译：苯丙氨酸烯酰胺衍生物
公开(公告)号：US06878718B2
公开(公告)日：2005-04-12
申请号：US10081072
申请日：2002-02-22
申请人： Stephen Brand , Stuart Bailey , Julien A. Brown , James A. Johnson , John R. Porter , John C. Head
发明人： Stephen Brand , Stuart Bailey , Julien A. Brown , James A. Johnson , John R. Porter , John C. Head
IPC分类号： A61K31/198 , A61K31/4375 , A61K31/44 , A61K31/4406 , A61K31/497 , A61P3/10 , A61P9/00 , A61P17/00 , A61P17/06 , A61P19/02 , A61P25/00 , A61P29/00 , A61P37/00 , A61P37/06 , A61P43/00 , C07C229/34 , C07C229/46 , C07C233/82 , C07C321/22 , C07C323/30 , C07D213/81 , C07D213/89 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D471/04
CPC分类号： C07D213/81 , C04B35/632 , C07C229/10 , C07C229/46 , C07C233/81 , C07C233/82 , C07C323/30 , C07C2601/04 , C07C2603/94 , C07C2603/96 , C07D213/79 , C07D213/89 , C07D311/96 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D471/04
摘要： Phenylalanine enamide derivatives of formula (1) are described: wherein R1 is a group Ar1L2Ar2Alk- in which: Ar1 is an optionally substituted aromatic or heteroaromatic group; L2 is a covalent bond or a linker atom or group; Ar2 is an optionally substituted arylene or heteroarylene group; and Alk is a chain —CH2—CH(R)—, —CH═C(R)— or in which R is a carboxylic acid (—CO2H) or a derivative or biostere thereof; X is an —O— or —S— atom or —N(R2)— group in which: Rx, Ry and Rz which may be the same or different is each a hydrogen atom or an optional substituent; or Rz is an atom or group as previously defined and Rx and Ry are joined together to form an optionally substituted spiro linked cycloaliphatic or heterocycloaliphatic group; and the salts, solvates, hydrates and N-oxides thereof. The compounds are able to inhibit the binding of integrins to their ligands and are of use in the prophylaxis and treatment of immuno or inflammatory disorders or disorders involving the inappropriate growth or migration of cells.
摘要翻译：描述了式（1）的苯丙氨酸烯酰胺衍生物：其中R 1是Ar 1 Ar 2 Ar 2 AlK-，其中：Ar 1是任选取代的芳族或杂芳族基团; 2>是共价键或连接原子或基团; Ar 2是任选取代的亚芳基或杂亚芳基; Alk是链-CH 2 -CH（R） - ， - CH = C（R） - ，其中 R是羧酸（-CO 2 H）或其衍生物或生物试剂; X是-O-或-S-原子或-N（R 2） - 基团，其中：R x，R y，和R a可以相同或不同，各自为氢原子或任选的取代基;或R z为前述定义的原子或基团，R x和R y连接在一起形成任选取代的螺环连接的脂环族或杂环脂族基团;及其盐，溶剂合物，水合物和N-氧化物。化合物能够抑制整联蛋白与其配体的结合，并且可用于预防和治疗免疫或炎性疾病或涉及其中的疾病细胞的适当生长或迁移。

7. 发明授权

US08147727B2 Methods and systems for forming ophthalmic lens mold assemblies 有权
标题翻译：用于形成眼镜片模具组件的方法和系统
公开(公告)号：US08147727B2
公开(公告)日：2012-04-03
申请号：US12763543
申请日：2010-04-20
申请人： Ian Bruce , Robert Oag , Stuart Bailey , Stephen Saunders
发明人： Ian Bruce , Robert Oag , Stuart Bailey , Stephen Saunders
IPC分类号： B29D11/00
CPC分类号： B29D11/005 , B29C33/202 , B29L2011/0041 , Y10S425/808
摘要： Methods and systems are provided for making an ophthalmic lens. The present methods and systems are effecting in coupling two mold sections together at two or more discrete regions. Embodiments of the methods and systems form a bore that extends completely through one of the mold sections and only partially through the other mold section. During formation of the bore, the mold material in proximity to the bore being foamed becomes molten and diffuses from the bore. A portion of the molten mold material is provided at a contact point between the two mold sections and when the molten material cools, the material foams a spot weld between the mold sections. By foaming multiple hollow spot welds in a mold assembly, the two mold sections can be securely coupled to each other during the manufacture of an ophthalmic lens, such as a silicone hydrogel contact lens.
摘要翻译：提供了用于制造眼科镜片的方法和系统。目前的方法和系统正在两个或更多个离散区域将两个模具部分联接在一起。方法和系统的实施例形成了一个完全穿过其中一个模具部分并且仅部分地穿过另一个模具部分的孔。在孔的形成期间，靠近所形成的孔的模具材料变得熔化并且从孔扩散。熔融模具材料的一部分设置在两个模具部分之间的接触点处，并且当熔融材料冷却时，该材料在模具部分之间形成点焊。通过在模具组件中形成多个中空点焊，在制造眼用透镜（例如硅酮水凝胶隐形眼镜）期间，两个模具部分可以彼此牢固地联接。

8. 发明授权

US07786177B2 Phenylalanine enamide derivatives 失效
标题翻译：苯丙氨酸烯酰胺衍生物
公开(公告)号：US07786177B2
公开(公告)日：2010-08-31
申请号：US12415546
申请日：2009-03-31
申请人： Stephen Brand , Stuart Bailey , Julien A. Brown , James A. Johnson , John R. Porter , John C. Head
发明人： Stephen Brand , Stuart Bailey , Julien A. Brown , James A. Johnson , John R. Porter , John C. Head
IPC分类号： C07D215/14 , A61K31/47 , A61K31/438 , A61P11/06 , A61P29/00
CPC分类号： C07D213/81 , C04B35/632 , C07C229/10 , C07C229/46 , C07C233/81 , C07C233/82 , C07C323/30 , C07C2601/04 , C07C2603/94 , C07C2603/96 , C07D213/79 , C07D213/89 , C07D311/96 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D471/04
摘要： Phenylalanine enamide derivatives of formula (1) are described: wherein R1 is a group Ar1 L2Ar2Alk- in which: Ar1 is an optionally substituted aromatic or heteroaromatic group; L2 is a covalent bond or a linker atom or group; Ar2 is an optionally substituted arylene or heteroarylene group; and Alk is a chain —CH2—CH(R)—, —CH═C(R)— or in which R is a carboxylic acid (—CO2H) or a derivative or biostere thereof; X is an —O— or —S— atom or —N(R2)— group in which: Rx, Ry and Rz which may be the same or different is each a hydrogen atom or an optional substituent; or Rz is an atom or group as previously defined and Rx and Ry are joined together to form an optionally substituted spiro linked cycloaliphatic or heterocycloaliphatic group; and the salts, solvates, hydrates and N-oxides thereof. The compounds are able to inhibit the binding of integrins to their ligands and are of use in the prophylaxis and treatment of immuno or inflammatory disorders or disorders involving the inappropriate growth or migration of cells.
摘要翻译：描述了式（1）的苯丙氨酸烯酰胺衍生物：其中R1是基团Ar1 L2Ar2Alk-，其中：Ar1是任选取代的芳族或杂芳族基团; L2是共价键或连接原子或基团; Ar 2是任选取代的亚芳基或亚杂芳基; 并且Alk是链-CH 2 -CH（R） - ， - CH = C（R） - 或其中R是羧酸（-CO 2 H）或其衍生物或生物试剂; X是-O-或-S-原子或-N（R 2） - 基团，其中：可以相同或不同的R x，R y和R z各自为氢原子或任选的取代基; 或R z是如先前定义的原子或基团，并且R x和R y连接在一起以形成任选取代的螺环连接的脂环族或杂环脂族基团; 及其盐，溶剂合物，水合物和N-氧化物。该化合物能够抑制整联蛋白与其配体的结合，并且可用于预防和治疗涉及细胞不适当生长或迁移的免疫或炎性疾病或病症。

9. 发明授权

US06235753B1 Inhibitors of the production of S-CD23 and the secretion of TNF 失效
标题翻译：产生S-CD23的抑制剂和TNF的分泌
公开(公告)号：US06235753B1
公开(公告)日：2001-05-22
申请号：US09180547
申请日：1999-01-21
申请人： Stuart Bailey , Andrew Faller , David Glynn Smith , Derek Richard Buckle
发明人： Stuart Bailey , Andrew Faller , David Glynn Smith , Derek Richard Buckle
IPC分类号： C07C25904
CPC分类号： C07D333/54 , C07C259/06 , C07D277/64 , C07D307/80 , C07D333/60
摘要： Inhibitors of the Production of s-CD23 and the secretion of TNF are provided.
摘要翻译：提供了s-CD23的产生抑制剂和TNF的分泌

10. 发明申请

US20120150914A1 AUTOMATIC ENFORCEMENT OF RELATIONSHIPS IN A DATABASE SCHEMA 有权
标题翻译：自动执行数据库样本中的关系
公开(公告)号：US20120150914A1
公开(公告)日：2012-06-14
申请号：US13316036
申请日：2011-12-09
申请人： Stuart Bailey , Srinath Gutti , Ivan Pulleyn
发明人： Stuart Bailey , Srinath Gutti , Ivan Pulleyn
IPC分类号： G06F17/30
CPC分类号： G06F17/30292 , G06F17/30371
摘要： A technique for enforcing a database relationship is disclosed. The technique includes specifying within a database schema a reference type that associates two structures and specifies the relationship between the two structures, and automatically generating code that checks the relationship between the two structures based on the specified reference in the database schema.
摘要翻译：公开了一种用于执行数据库关系的技术。该技术包括在数据库模式中指定引用类型，该引用类型将两个结构相关联并指定两个结构之间的关系，并自动生成基于数据库模式中指定引用来检查两个结构之间的关系的代码。

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