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1. 发明授权

US07446230B2 Dibenzoylmethane-based compounds, use as photoactivatable sunscreens and cosmetic compositions containing them 失效
标题翻译：二苯甲酰基甲烷基化合物，用作可光活化防晒剂和含有它们的化妆品组合物
公开(公告)号：US07446230B2
公开(公告)日：2008-11-04
申请号：US10564888
申请日：2004-07-15
申请人： Isabelle Rico-Lattes , Fabienne Wetz , Corinne Routaboul , Alain Denis
发明人： Isabelle Rico-Lattes , Fabienne Wetz , Corinne Routaboul , Alain Denis
IPC分类号： C07C49/00 , A61K8/00
CPC分类号： A61Q17/04 , A61K8/35 , A61K2800/52 , C07C49/84
摘要： The present invention relates to dibenzoylmethane-based compounds of formula 1, and also to salts or solvates thereof, and to the process for preparing them. The invention also relates to the use of a compound of formula (I) as an agent for protecting the skin or the hair against UV radiation and to a cosmetic and/or dermatological product, characterized in that it comprises a compound of formula (I) as active principle.
摘要翻译：本发明涉及式1的二苯甲酰甲烷类化合物及其盐或溶剂合物及其制备方法。本发明还涉及式（I）化合物作为保护皮肤或毛发免受紫外线辐射的药剂和化妆品和/或皮肤病学产品的用途，其特征在于其包含式（I）化合物，作为积极的原则。

2. 发明申请

US20070025930A1 Dibenzoilmethane derivative compounds, the use thereof in the form of photoactivable solar filters and cosmetic compositions containing said compounds 失效
标题翻译：二苄氧基甲烷衍生物化合物，其可光活性太阳能过滤器和含有所述化合物的化妆品组合物的用途
公开(公告)号：US20070025930A1
公开(公告)日：2007-02-01
申请号：US10564888
申请日：2004-07-15
申请人： Isabelle Rico-Lattes , Fabienne Wetz , Corinne Routaboul , Alain Denis
发明人： Isabelle Rico-Lattes , Fabienne Wetz , Corinne Routaboul , Alain Denis
IPC分类号： A61K8/41 , C07C69/95 , A61K8/35 , C07C205/45
CPC分类号： A61Q17/04 , A61K8/35 , A61K2800/52 , C07C49/84
摘要： The present invention relates to dibenzoylmethane-based compounds of formula 1, and also to salts or solvates thereof, and to the process for preparing them. The invention also relates to the use of a compound of formula (I) as an agent for protecting the skin or the hair against UV radiation and to a cosmetic and/or dermatological product, characterized in that it comprises a compound of formula (I) as active principle.
摘要翻译：本发明涉及式1的二苯甲酰甲烷类化合物及其盐或溶剂合物及其制备方法。本发明还涉及式（I）化合物作为保护皮肤或毛发免受紫外线辐射的药剂和化妆品和/或皮肤病学产品的用途，其特征在于其包含式（I）化合物，作为积极的原则。

3. 发明授权

US08231884B2 Diffusing particles based on organogelling xerogel fibers, method for preparing same and use in cosmetic formulations 失效
标题翻译：基于有机凝胶干凝胶纤维扩散颗粒，其制备方法和用于化妆品制剂中
公开(公告)号：US08231884B2
公开(公告)日：2012-07-31
申请号：US11992659
申请日：2006-09-29
申请人： Anne Doat , Emile Perez , Isabelle Rico-Lattes , Pascal Bordat
发明人： Anne Doat , Emile Perez , Isabelle Rico-Lattes , Pascal Bordat
IPC分类号： A61K8/60 , A61K8/11 , A61Q19/00
CPC分类号： A61K8/11 , A61K8/60 , A61Q1/00
摘要： The invention concerns particles consisting essentially of fibers of an organogelling substance in the form of xerogel (dry gel), the fibers being essentially oriented in a common direction and randomly aligned around the longest fiber. The organogelling substance is preferably 1,3: 2,4-di-O-benzylidene-D-sorbitol. Said particles, which are in the form of spindles, have interesting optical properties; they have a total light transmittance higher than 0.80, with a diffuse transmittance higher than the specular transmittance. The invention also concerns a method for preparing said particles by solvent evaporation process, by solvent diffusion/evaporation process or by shearing process. The invention finally concerns active particles consisting of said particles whereon is immobilized a dermocosmetically active principle, a dermocosmetic composition comprising said particles or said active particles and a cosmetic treatment method which consists in applying on the skin said dermocosmetic composition.
摘要翻译：本发明涉及基本上由干凝胶（干凝胶）形式的有机凝胶物质的纤维组成的颗粒，该纤维基本上沿着共同的方向定向并随机地排列在最长的纤维周围。有机凝胶物质优选为1,3：2,4-二-O-亚苄基-D-山梨糖醇。呈心轴形式的所述颗粒具有有趣的光学性质; 它们的总透光率高于0.80，漫透射率高于镜面透光率。本发明还涉及通过溶剂蒸发法，溶剂扩散/蒸发法或剪切法制备所述颗粒的方法。本发明最终涉及由所述颗粒组成的活性颗粒，其中固定有皮肤发光活性成分，包含所述颗粒或所述活性颗粒的皮肤外用剂组合物和在皮肤上施用所述皮肤油性组合物的美容处理方法。

4. 发明授权

US07666847B2 Medicament comprising a reducing alkyl-sugar monomer for the treatment of inflammatory disorders 有权
标题翻译：药物包含用于治疗炎症性疾病的还原性烷基糖单体
公开(公告)号：US07666847B2
公开(公告)日：2010-02-23
申请号：US10577444
申请日：2004-10-29
申请人： Jean-Philippe Houlmont , Isabelle Rico-Lattes , Emile Perez , Pascal Bordat
发明人： Jean-Philippe Houlmont , Isabelle Rico-Lattes , Emile Perez , Pascal Bordat
IPC分类号： A61K31/7028 , C07G3/00
CPC分类号： C07H3/02 , A61K8/602 , A61K31/7004 , A61K31/7028 , A61Q19/08 , C07H15/04
摘要： The invention relates to a medicament comprising at least one reducing alkyl-sugar monomer having a hydroxyl function which is substituted by an alkoxy radical at C2-C40, said medicament being preferably intended to regulate inflammatory mechanisms. The reducing sugar is preferably selected from the group containing rhamnose, fucose and glucose. The invention also relates to a cosmetic treatment method involving the topical application of a composition comprising at least one reducing alkyl-sugar monomer having a hydroxyl function which is substituted by an alkoxy radical at C2-C40.
摘要翻译：本发明涉及包含至少一种具有羟基官能团的还原性烷基糖单体的药物，其在C2-C40被取代为烷氧基，所述药物优选用于调节炎症机制。还原糖优选选自含有鼠李糖，岩藻糖和葡萄糖的组。本发明还涉及一种美容治疗方法，涉及局部施用组合物，其包含至少一种具有羟基官能团的还原性烷基糖单体，其在C 2 -C 40被烷氧基取代。

5. 发明申请

US20070134187A1 Medicament comprising a reducing alkyl-sugar monomer for the treatment of inflammatory disorders 有权
标题翻译：药物包含用于治疗炎症性疾病的还原性烷基糖单体
公开(公告)号：US20070134187A1
公开(公告)日：2007-06-14
申请号：US10577444
申请日：2004-10-29
申请人： Jean-Philippe Houlmont , Isabelle Rico-Lattes , Emile Perez , Pascal Bordat
发明人： Jean-Philippe Houlmont , Isabelle Rico-Lattes , Emile Perez , Pascal Bordat
IPC分类号： A61K31/70 , A61K31/715 , A61K8/73
CPC分类号： C07H3/02 , A61K8/602 , A61K31/7004 , A61K31/7028 , A61Q19/08 , C07H15/04
摘要： The invention relates to a medicament comprising at least one reducing alkyl-sugar monomer having a hydroxyl function which is substituted by an alkoxy radical at C2-C40, said medicament being preferably intended to regulate inflammatory mechanisms. The reducing sugar is preferably selected from the group containing rhamnose, fucose and glucose. The invention also relates to a cosmetic treatment method involving the topical application of a composition comprising at least one reducing alkyl-sugar monomer having a hydroxyl function which is substituted by an alkoxy radical at C2-C40.
摘要翻译：本发明涉及一种药物，其包含至少一种具有羟基官能团的还原性烷基糖单体，其在C 2 -C 40取代基被烷氧基取代，所述药物为优选旨在调节炎症机制。还原糖优选选自含有鼠李糖，岩藻糖和葡萄糖的组。本发明还涉及一种美容治疗方法，其涉及局部施用包含至少一种具有羟基官能团的还原性烷基糖单体的组合物，该单体在C 2 -C 3 > 40 。

6. 发明授权

US09163049B2 Medicament comprising a reducing alkyl-sugar monomer for the treatment of inflammatory disorders 有权
标题翻译：药物包含用于治疗炎症性疾病的还原性烷基糖单体
公开(公告)号：US09163049B2
公开(公告)日：2015-10-20
申请号：US12559107
申请日：2009-09-14
申请人： Jean-Philippe Houlmont , Isabelle Rico-Lattes , Emile Perez , Pascal Bordat
发明人： Jean-Philippe Houlmont , Isabelle Rico-Lattes , Emile Perez , Pascal Bordat
IPC分类号： C07H15/04 , A61K31/7004 , A61K31/7028 , C07H3/02 , A61K8/60 , A61Q19/08
CPC分类号： C07H3/02 , A61K8/602 , A61K31/7004 , A61K31/7028 , A61Q19/08 , C07H15/04
摘要： The invention relates to a medicament comprising at least one reducing alkyl-sugar monomer having a hydroxyl function which is substituted by an alkoxy radical at C2-C40, said medicament being preferably intended to regulate inflammatory mechanisms. The reducing sugar is preferably selected from the group containing rhamnose, fucose and glucose. The invention also relates to a cosmetic treatment method involving the topical application of a composition comprising at least one reducing alkyl-sugar monomer having a hydroxyl function which is substituted by an alkoxy radical at C2-C40.
摘要翻译：本发明涉及包含至少一种具有羟基官能团的还原性烷基糖单体的药物，其在C2-C40被取代为烷氧基，所述药物优选用于调节炎症机制。还原糖优选选自含有鼠李糖，岩藻糖和葡萄糖的组。本发明还涉及一种美容治疗方法，涉及局部施用组合物，其包含至少一种具有羟基官能团的还原性烷基糖单体，其在C 2 -C 40被烷氧基取代。

7. 发明申请

US20120214756A1 COOPERATIVE CONVEYANCE OF BASIC ACTIVE PRINCIPLES BY AMPHIPHILIC ACID MOLECULES 有权
标题翻译：基本活性原子的合成输送通过分子式
公开(公告)号：US20120214756A1
公开(公告)日：2012-08-23
申请号：US13499197
申请日：2010-10-04
申请人： Cécile Bize , Muriel Blanzat , Emile Perez , Isabelle Rico-Lattes
发明人： Cécile Bize , Muriel Blanzat , Emile Perez , Isabelle Rico-Lattes
IPC分类号： A61K31/70 , C07H15/26
CPC分类号： A61K9/0014 , A61K31/5415 , A61K47/26 , A61K47/541
摘要： The present invention relates to an intermolecular association complex of an amphiphilic carrier and an active principle G, having the following general formula (I), as well as to the compositions containing same, to the uses thereof, particularly as a drug, and to the method for preparing same.
摘要翻译：本发明涉及具有以下通式（I）的两亲性载体和活性成分G的分子间缔合络合物及其含有的组合物，其用途，特别是作为药物，以及制备方法

8. 发明申请

US20100069311A1 MEDICAMENT COMPRISING A REDUCING ALKYL-SUGAR MONOMER FOR THE TREATMENT OF INFLAMMATORY DISORDERS 审中-公开
标题翻译：包含减少用于治疗炎症性疾病的亚克力糖单体的药物
公开(公告)号：US20100069311A1
公开(公告)日：2010-03-18
申请号：US12559107
申请日：2009-09-14
申请人： Jean-Philippe Houlmont , Isabelle Rico-Lattes , Emile Perez , Pascal Bordat
发明人： Jean-Philippe Houlmont , Isabelle Rico-Lattes , Emile Perez , Pascal Bordat
IPC分类号： A61K8/60 , A61Q19/00
CPC分类号： C07H3/02 , A61K8/602 , A61K31/7004 , A61K31/7028 , A61Q19/08 , C07H15/04
摘要： The invention relates to a medicament comprising at least one reducing alkyl-sugar monomer having a hydroxyl function which is substituted by an alkoxy radical at C2-C40, said medicament being preferably intended to regulate inflammatory mechanisms. The reducing sugar is preferably selected from the group containing rhamnose, fucose and glucose. The invention also relates to a cosmetic treatment method involving the topical application of a composition comprising at lest one reducing alkyl-sugar monomer having a hydroxyl function which is substituted by an alkoxy radical at C2-C40.
摘要翻译：本发明涉及包含至少一种具有羟基官能团的还原性烷基糖单体的药物，其在C2-C40被取代为烷氧基，所述药物优选用于调节炎症机制。还原糖优选选自含有鼠李糖，岩藻糖和葡萄糖的组。本发明还涉及一种美容治疗方法，其涉及局部施用组合物，其中包含至少一种具有羟基官能团的还原性烷基糖单体，其在C2-C40被烷氧基取代。

9. 发明申请

US20090137656A1 Intermolecular Association Complex of a Carrier and of an Active Principle 审中-公开
标题翻译：载体和活性原子的分子间缔合复合物
公开(公告)号：US20090137656A1
公开(公告)日：2009-05-28
申请号：US11989210
申请日：2006-07-21
申请人： Sabrina Consola , Muriel Blanzat , Isabelle Rico-Lattes , Emile Perez , Pascal Bordat
发明人： Sabrina Consola , Muriel Blanzat , Isabelle Rico-Lattes , Emile Perez , Pascal Bordat
IPC分类号： A61K31/405 , A61K31/192 , A61P29/00 , A61K31/201
CPC分类号： A61K47/36 , A61K9/146 , A61K9/19
摘要： The invention relates to an intermolecular association complex of formula (I) of an amphiphilic carrier and of an active principle Z-Y, in which; S, X n, R1, R2, R3, Y, Z are as defined in the description.
摘要翻译：本发明涉及两亲载体和活性成分Z-Y的式（I）的分子间缔合络合物，其中; S，X n，R 1，R 2，R 3，Y，Z如说明书中所定义。

10. 发明申请

US20070135378A1 Method for the direct synthesis of oligorhamnosides, composition comprising oligorhamnosides and use thereof as a medicament 审中-公开
标题翻译：直接合成寡头孢他啶的方法，包含寡头孢他啶的组合物及其作为药物的用途
公开(公告)号：US20070135378A1
公开(公告)日：2007-06-14
申请号：US10577654
申请日：2004-10-29
申请人： Jean-Philippe Houlmont , Isabelle Rico-Lattes , Emile Perez , Pascal Bordat
发明人： Jean-Philippe Houlmont , Isabelle Rico-Lattes , Emile Perez , Pascal Bordat
IPC分类号： C12P19/04 , A61K31/715
CPC分类号： A61K8/73 , A61K8/60 , A61K31/48 , A61K31/70 , A61K31/702 , A61K31/715 , A61Q19/00 , A61Q19/005 , A61Q19/08 , C07H3/06 , C07H15/04
摘要： The invention relates to a method of preparing oligorhamnosides, comprising a one-pot reaction in acetonitrile without any rhamnose protection or deprotection reaction. The invention also relates to a composition a mixture of oligorhamnosides, which can be obtained using said method and which has between 2 and 12 rhamnose units. The invention further relates to a medicament comprising said composition, which is preferably intended to regulate inflammatory mechanisms, and to a cosmetic treatment method.
摘要翻译：本发明涉及一种制备寡核苷酸的方法，其包括在乙腈中的一锅反应，而没有任何鼠李糖保护或去保护反应。本发明还涉及可以使用所述方法获得并且具有2至12个鼠李糖单元的低聚半乳糖苷的混合物的组合物。本发明还涉及包含所述组合物的药物，其优选旨在调节炎症机制，以及美容治疗方法。

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