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1. 发明申请

US20070038150A1 TEST MAGAZINE AND METHOD FOR PROCESSING THE SAME 有权
标题翻译：测试杂志及其处理方法
公开(公告)号：US20070038150A1
公开(公告)日：2007-02-15
申请号：US11537791
申请日：2006-10-02
申请人： Irio Calasso , Martin Kopp , Charles Raney , Steven Roe
发明人： Irio Calasso , Martin Kopp , Charles Raney , Steven Roe
IPC分类号： A61B5/00 , A61B17/32
CPC分类号： A61B5/15169 , A61B5/1411 , A61B5/14532 , A61B5/150022 , A61B5/150358 , A61B5/150419 , A61B5/150503 , A61B5/15146 , A61B5/15151 , A61B5/15155 , A61B5/15167 , A61B5/15171 , A61B5/15173 , A61B5/15178 , A61B5/15184 , A61B5/157 , Y10T436/110833
摘要： A test magazine with two film strips (12, 14), which are joined to one another in a sandwich-like manner, can be wound up, and between which holding cells (16) for test elements are kept free. The test magazine also comprises a multitude of test elements (18, 20) each having a puncturing unit (18) for inserting into body tissue and a test unit (20) for being subjected to body fluid. To this end, the puncturing units (18) and test units (20) are placed in separate holding cells (16) whereby separating them from one another.
摘要翻译：可以卷起具有以夹心状连接的两个胶片条（12,14）的测试盒，并且在其间保持用于测试元件的保持盒（16）。测试盒还包括多个测试元件（18,20），每个测试元件具有用于插入身体组织的穿刺单元（18）和用于体液的测试单元（20）。为此，将穿刺单元（18）和测试单元（20）放置在分离的保持单元（16）中，从而将它们彼此分离。

2. 发明申请

US20070026442A1 Analytical method and device 审中-公开
标题翻译：分析方法和装置
公开(公告)号：US20070026442A1
公开(公告)日：2007-02-01
申请号：US11492753
申请日：2006-07-24
申请人： Irio Calasso , Martin Kopp , Roger Sandoz
发明人： Irio Calasso , Martin Kopp , Roger Sandoz
IPC分类号： C12Q1/68 , C12P19/34 , C12M1/34
CPC分类号： G01N33/5308 , G01N33/54313
摘要： A method is provided that conveniently allows rapid amplification of nucleic acids. Two different heat sources are used to heat the reaction mixture.
摘要翻译：提供了方便地允许核酸的快速扩增的方法。使用两种不同的热源来加热反应混合物。

3. 发明申请

US20070016103A1 BODY FLUID SAMPLING DEVICE 有权
标题翻译：身体液体取样装置
公开(公告)号：US20070016103A1
公开(公告)日：2007-01-18
申请号：US11470368
申请日：2006-09-06
申请人： Irio Calasso , Patrick Griss , Emad Sarofim , Rainer Jaeggi , Uwe Kraemer , Dave Hasker , Volker Zimmer , Wilfried Schmid , Otto Fuerst , Hans List , Hans-Peter Haar , Theo Arnitz , Steven Roe
发明人： Irio Calasso , Patrick Griss , Emad Sarofim , Rainer Jaeggi , Uwe Kraemer , Dave Hasker , Volker Zimmer , Wilfried Schmid , Otto Fuerst , Hans List , Hans-Peter Haar , Theo Arnitz , Steven Roe
IPC分类号： A61B5/00
CPC分类号： A61B5/1411 , A61B5/14532 , A61B5/1486 , A61B5/150022 , A61B5/150068 , A61B5/150282 , A61B5/150358 , A61B5/150396 , A61B5/150419 , A61B5/150427 , A61B5/15045 , A61B5/150503 , A61B5/15151 , A61B5/15163
摘要： Body fluid sampling device comprising a skin-piercing element having a collection zone for receiving body fluid, and the device further comprising a fluid receiving means remote spaced apart from the collection zone so that body fluid in the collection zone will not contact the fluid receiving means initially. The collection zone takes up a very small volume of body fluid of about 10 to 500 nl in a very short time period of less than 0.5 seconds. The fluid receiving means may have a test zone for performing an analytical reaction. Fluid sample from the collection zone is automatically or manually transported to the fluid receiving means to contact the fluid with the test zone.
摘要翻译：体液取样装置包括具有用于接收体液的收集区的皮肤刺穿元件，并且该装置还包括与收集区间隔开的流体接收装置，使得收集区中的体液不会接触流体接收装置原来。收集区在小于0.5秒的非常短的时间段内占据非常小体积的体液约10至500nl。流体接收装置可以具有用于进行分析反应的测试区域。来自收集区的流体样品被自动或手动地输送到流体接收装置以使流体与测试区接触。

4. 发明申请

US20110257493A1 BODY FLUID SAMPLING DEVICE 有权
标题翻译：身体液体取样装置
公开(公告)号：US20110257493A1
公开(公告)日：2011-10-20
申请号：US13167243
申请日：2011-06-23
申请人： Irio Calasso , Patrick Griss , Emad Sarofim , Rainer Jaeggi , Uwe Kraemer , Dave Hasker , Volker Zimmer
发明人： Irio Calasso , Patrick Griss , Emad Sarofim , Rainer Jaeggi , Uwe Kraemer , Dave Hasker , Volker Zimmer
IPC分类号： A61B5/157 , A61B5/15
CPC分类号： A61B5/14532 , A61B5/1411 , A61B5/1486 , A61B5/150022 , A61B5/150251 , A61B5/150297 , A61B5/150358 , A61B5/150419 , A61B5/150435 , A61B5/150503 , A61B5/15107 , A61B5/15117
摘要： Body fluid sampling device comprising a sampling element having a fluid pathway (11) for receiving body fluid, at least a portion of the fluid pathway is open to the environment and further comprising a fluid receiving means (40) being spaced from the fluid pathway so that fluid in the pathway will not contact the fluid receiving means initially. The fluid receiving means has two or more test zones (45) for performing analytical reactions. Fluid from the channel is contacted with the fluid receiving means either by bringing the fluid receiving means and the fluid into mechanical contact or by electrically transporting fluid from the channel onto the fluid receiving means.
摘要翻译：体液取样装置包括具有用于接收体液的流体通道（11）的采样元件，流体通路的至少一部分对环境开放，并且还包括与流体通道间隔开的流体接收装置（40）路径中的流体最初不会接触流体接收装置。流体接收装置具有用于进行分析反应的两个或更多个测试区（45）。来自通道的流体通过使流体接收装置和流体机械接触或者将流体从流路电输送到流体接收装置上而与流体接收装置接触。

5. 发明申请

US20080294064A1 Lancing Element, Lancing System and a Method for Skin Detection 审中-公开
标题翻译： Lancing Element，Lancing系统和皮肤检测方法
公开(公告)号：US20080294064A1
公开(公告)日：2008-11-27
申请号：US12118146
申请日：2008-05-09
申请人： Irio Calasso , Oliver Bruendler , Michael Glauser , Hans-Peter Wahl , Stephan Korner
发明人： Irio Calasso , Oliver Bruendler , Michael Glauser , Hans-Peter Wahl , Stephan Korner
IPC分类号： A61B5/151 , A61B5/053
CPC分类号： A61B5/157 , A61B5/14532 , A61B5/150022 , A61B5/150068 , A61B5/150175 , A61B5/150358 , A61B5/150419 , A61B5/150435 , A61B5/150503 , A61B5/150954 , A61B5/15107 , A61B5/1519 , A61B5/15194
摘要： In the case of a disposable lancing element for collecting body fluid through the skin comprising a support and a lancing member which distally projects therefrom and can pierce the skin in a lancing movement, it is proposed that a pretensioning means which tightens the skin in the area of the puncture site is arranged on the support and has a contact member which impacts the skin laterally from the lancing member during the lancing movement.
摘要翻译：在用于通过皮肤收集体液的一次性穿刺元件的情况下，包括支撑件和远离其突出的穿刺构件，并且可以在穿刺运动中刺穿皮肤，所以提出一种预紧机构，其将区域中的皮肤收紧穿刺部位布置在支撑件上并且具有在穿刺运动期间从穿刺构件侧向冲击皮肤的接触构件。

6. 发明授权

US08394117B2 Handheld apparatus for creating a puncture wound 有权
标题翻译：用于创建穿刺伤口的手持设备
公开(公告)号：US08394117B2
公开(公告)日：2013-03-12
申请号：US12040905
申请日：2008-03-02
申请人： Heinz-Michael Hein , Irio Calasso , Hans List
发明人： Heinz-Michael Hein , Irio Calasso , Hans List
IPC分类号： A61B17/14 , A61B17/32 , A61B17/34 , B26F1/24
CPC分类号： A61B5/157 , A61B5/150022 , A61B5/150068 , A61B5/150152 , A61B5/150175 , A61B5/150419 , A61B5/150427 , A61B5/150511 , A61B5/15123 , A61B5/1519 , A61B5/15194 , Y10T83/0481
摘要： The invention relates to a method for creating a puncture wound for obtaining a sample of a body fluid from a body part in which a skin opening is created at a puncture site in the epidermis in a skin-opening step. Then, in a sample collection step a sample collection puncture is executed by using a puncture element with which the skin opening is deepened with the puncture element, thereby creating a puncture wound for obtaining the sample. The invention also relates to a handheld apparatus for implementing this method.
摘要翻译：本发明涉及一种创造穿刺伤口的方法，该穿刺伤口从皮肤开放步骤中在表皮的穿刺位置处产生皮肤开口的身体部位获得体液样品。然后，在取样步骤中，通过使用与穿刺元件加深皮肤开口的穿刺元件进行样本采集穿刺，由此形成用于获取样本的穿刺伤口。本发明还涉及一种用于实现该方法的手持设备。

7. 发明申请

US20110196337A1 Modular Drug Delivery Device for Administering Discrete Doses of a Medicament 有权
标题翻译：用于管理药物离散剂量的模块化药物递送装置
公开(公告)号：US20110196337A1
公开(公告)日：2011-08-11
申请号：US12672003
申请日：2008-08-04
申请人： Derek Brandt , Irio Calasso
发明人： Derek Brandt , Irio Calasso
IPC分类号： A61M5/142
CPC分类号： A61M5/1413 , A61M5/14248 , A61M5/1723 , A61M2005/14268 , A61M2230/201
摘要： There provided a drug delivery device adapted for providing a plurality of discrete doses of a medicament including a disposable delivery unit (2) adapted to be worn by a user, comprising a reservoir (10b) for holding a medicament to be delivered, an injection member (22) adapted for trans-dermal drug delivery, and a pump (12) adapted for pumping the medicament to be delivered from the reservoir (10b) to the injection member (22); and a separate reusable base unit (4) comprising a drive module for driving the pump (12). The pump in the disposable delivery unit is activated to deliver a dose of the medicament by bringing the base unit temporarily into communication with the delivery unit.
摘要翻译：提供了适于提供多个离散剂量的药物的药物输送装置，所述药物包括适于由使用者佩戴的一次性输送单元（2），包括用于保持要输送的药物的储存器（10b），注射构件（22），以及适于泵送待从所述储存器（10b）传送到所述注射构件（22）的药物的泵（12）; 以及包括用于驱动泵（12）的驱动模块的单独的可重复使用的基本单元（4）。一次性输送单元中的泵被激活以通过使基部单元暂时与输送单元连通来递送剂量的药物。

8. 发明申请

US20070197937A1 Microfluid system and method for production thereof 审中-公开
标题翻译：微流体系统及其生产方法
公开(公告)号：US20070197937A1
公开(公告)日：2007-08-23
申请号：US11676398
申请日：2007-02-19
申请人： Emad Sarofim , Irio Calasso , Patrick Griss
发明人： Emad Sarofim , Irio Calasso , Patrick Griss
IPC分类号： A61B5/00
CPC分类号： B01L3/502707 , A61B5/14532 , A61B5/150022 , A61B5/150282 , A61B5/150358 , A61B5/15045 , A61B5/15105 , A61B5/15142 , A61B2562/0295 , B01L3/502746 , B01L2200/12 , B01L2300/0825 , B01L2400/0406
摘要： The invention generally concerns a microfluidic system having a support body provided with a lancing member and a semi-open microchannel, for the capillary transport of a sample fluid from a receiving site to a target site. In order to obtain a higher aspect ratio the support body is coated with a build-up layer which laterally defines the microchannel in the upper region.
摘要翻译：本发明一般涉及具有支撑体的微流体系统，所述支撑体设有穿刺构件和半开放微通道，用于将样品流体从接收部位毛细管输送到目标部位。为了获得更高的纵横比，支撑体涂覆有在上部区域中侧向限定微通道的积聚层。

9. 发明授权

US08414532B2 Modular drug delivery device for administering discrete doses of a medicament 有权
标题翻译：用于给予离散剂量的药物的模块化药物递送装置
公开(公告)号：US08414532B2
公开(公告)日：2013-04-09
申请号：US12672003
申请日：2008-08-04
申请人： Derek Brandt , Irio Calasso
发明人： Derek Brandt , Irio Calasso
IPC分类号： A61M5/14
CPC分类号： A61M5/1413 , A61M5/14248 , A61M5/1723 , A61M2005/14268 , A61M2230/201
摘要： There provided a drug delivery device adapted for providing a plurality of discrete doses of a medicament including a disposable delivery unit (2) adapted to be worn by a user, comprising a reservoir (10b) for holding a medicament to be delivered, an injection member (22) adapted for trans-dermal drug delivery, and a pump (12) adapted for pumping the medicament to be delivered from the reservoir (10b) to the injection member (22); and a separate reusable base unit (4) comprising a drive module for driving the pump (12). The pump in the disposable delivery unit is activated to deliver a dose of the medicament by bringing the base unit temporarily into communication with the delivery unit.
摘要翻译：提供了适于提供多个离散剂量的药物的药物输送装置，所述药物包括适于由使用者佩戴的一次性输送单元（2），包括用于保持要输送的药物的储存器（10b），注射构件（22），以及适于泵送待从所述储存器（10b）传送到所述注射构件（22）的药物的泵（12）; 以及包括用于驱动所述泵（12）的驱动模块的单独的可重复使用的基本单元（4）。一次性输送单元中的泵被激活以通过使基部单元暂时与输送单元连通来递送剂量的药物。

10. 发明申请

US20080208079A1 METHOD FOR CREATING A PUNCTURE WOUND AND HANDHELD APPARATUS SUITABLE THEREFOR 有权
标题翻译：用于创建适合其的打孔和手持装置的方法
公开(公告)号：US20080208079A1
公开(公告)日：2008-08-28
申请号：US12040905
申请日：2008-03-02
申请人： Heinz-Michael Hein , Irio Calasso , Hans List
发明人： Heinz-Michael Hein , Irio Calasso , Hans List
IPC分类号： A61B5/15
CPC分类号： A61B5/157 , A61B5/150022 , A61B5/150068 , A61B5/150152 , A61B5/150175 , A61B5/150419 , A61B5/150427 , A61B5/150511 , A61B5/15123 , A61B5/1519 , A61B5/15194 , Y10T83/0481
摘要： The invention relates to a method for creating a puncture wound for obtaining a sample of a body fluid from a body part in which a skin opening is created at a puncture site in the epidermis in a skin-opening step. Then, in a sample collection step a sample collection puncture is executed by using a puncture element with which the skin opening is deepened with the puncture element, thereby creating a puncture wound for obtaining the sample. The invention also relates to a handheld apparatus for implementing this method.
摘要翻译：本发明涉及一种创造穿刺伤口的方法，该穿刺伤口从皮肤开放步骤中在表皮的穿刺位置处产生皮肤开口的身体部位获得体液样品。然后，在取样步骤中，通过使用与穿刺元件加深皮肤开口的穿刺元件进行样本采集穿刺，由此形成用于获取样本的穿刺伤口。本发明还涉及一种用于实现该方法的手持设备。

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