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    • 1. 发明申请
    • Breath Test Device and Method
    • 呼吸试验装置及方法
    • US20100036273A1
    • 2010-02-11
    • US12084629
    • 2006-11-12
    • Ilan Ben-OrenAvarham HershkowitzEli KaplanYaron Ilan
    • Ilan Ben-OrenAvarham HershkowitzEli KaplanYaron Ilan
    • A61B5/08
    • A61K51/04A61K51/0402A61K51/1206A61K51/1268B82Y5/00G06F19/00
    • The disclosure relates breath test devices and methods for the evaluation of liver functional and metabolic capacity or to assess liver heath and/or degree of liver injury. Specifically, there is provided a method of evaluating a liver condition, the method includes on-line monitoring a metabolic product of methacetin, a salt or a derivative of methacetin, in a subject's breath after administering to the subject isotope labeled methacetin, a salt or a derivative thereof in water solution form. There is also provided a device for evaluating a liver condition, the device includes one or more sensors adapted to monitor on-line an isotope level of a metabolic product of labeled methacetin, or a salt or a derivative of methacetin in a subject's breath and a controller adapted to sample measurements of the one or more sensors at a continuous mode.
    • 本公开涉及用于评估肝功能和代谢能力的呼吸测试装置和方法,或评估肝脏健康和/或肝损伤程度。 具体地,提供了一种评估肝脏状况的方法,该方法包括在对受试者同位素标记的美沙西丁施用之后,在受试者的呼吸中在线监测美沙西丁,美沙西丁的盐或衍生物的代谢产物,盐或 其衍生物为水溶液形式。 还提供了一种用于评估肝脏状况的装置,该装置包括一个或多个传感器,适用于在线监测标记的美沙西丁的代谢产物的同位素水平,或受试者呼吸中的美沙西丁的盐或衍生物, 控制器适于在连续模式下采样所述一个或多个传感器的测量。
    • 2. 发明授权
    • Breath test device and method
    • 呼气试验装置及方法
    • US08622920B2
    • 2014-01-07
    • US12084629
    • 2006-11-12
    • Ilan Ben-OrenAvraham HershkowitzEli KaplanYaron Ilan
    • Ilan Ben-OrenAvraham HershkowitzEli KaplanYaron Ilan
    • A61K51/00A61B5/097
    • A61K51/04A61K51/0402A61K51/1206A61K51/1268B82Y5/00G06F19/00
    • The disclosure relates to breath test devices and methods for the evaluation of liver functional and metabolic capacity or to assess liver heath and/or degree of liver injury. Specifically, there is provided a method of evaluating a liver condition, the method includes on-line monitoring a metabolic product of methacetin, a salt or a derivative of methacetin, in a subject's breath after administering to the subject isotope labeled methacetin, a salt or a derivative thereof in water solution form. There is also provided a device for evaluating a liver condition, the device includes one or more sensors adapted to monitor on-line an isotope level of a metabolic product of labeled methacetin, or a salt or a derivative of methacetin in a subject's breath and a controller adapted to sample measurements of the one or more sensors at a continuous mode.
    • 本公开涉及用于评估肝功能和代谢能力或评估肝脏健康和/或肝损伤程度的呼吸测试装置和方法。 具体地,提供了一种评估肝脏状况的方法,该方法包括在对受试者同位素标记的美沙西丁施用之后,在受试者的呼吸中在线监测美沙西丁,美沙西丁的盐或衍生物的代谢产物,盐或 其衍生物为水溶液形式。 还提供了一种用于评估肝脏状况的装置,该装置包括一个或多个传感器,适用于在线监测标记的美沙西丁的代谢产物的同位素水平,或受试者呼吸中的美沙西丁的盐或衍生物, 控制器适于在连续模式下采样所述一个或多个传感器的测量。