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    • 4. 发明授权
    • Facilitating comparison of medical images
    • 促进医学图像的比较
    • US07769216B2
    • 2010-08-03
    • US11323939
    • 2005-12-29
    • Takeshi DoiVilim SimcicJimmy R. Roehrig
    • Takeshi DoiVilim SimcicJimmy R. Roehrig
    • G06K9/00
    • G06F19/321G06F19/00G16H50/20
    • Facilitating viewer comparison of a plurality of medical images of at least one body part on a softcopy review workstation is described. First and second medical images are displayed such that the second medical image appears as a spatially registered underlay to the first medical image exposed through an aperture therein. The aperture comprises at least one edge that is viewer-manipulable in a back-and-forth manner so that the first and second medical images can be visually compared with minimal eye movement. For a temporal comparison embodiment, the first and second medical images comprise identical views of the same body part acquired at different times. For a cross-modality comparison embodiment, the first and second medical images are acquired substantially concurrently, or at different times, using different medical imaging modalities. For a bilateral comparison embodiment, the first and second images are corresponding views of two laterally corresponding body parts.
    • 描述了在软拷贝检查工作站上促进对至少一个身体部位的多个医学图像的观看者比较。 显示第一和第二医疗图像,使得第二医疗图像作为空间注册的底层显示出通过其中的孔暴露的第一医疗图像。 所述孔包括至少一个能够以往复方式观察者操纵的边缘,使得可以在视觉上比较第一和第二医学图像与最小的眼睛运动。 对于时间比较实施例,第一和第二医学图像包括在不同时间获取的相同身体部位的相同视图。 对于交叉模态比较实施例,使用不同的医学成像模式基本同时或不同时间获取第一和第二医学图像。 对于双向比较实施例,第一和第二图像是两个横向对应的身体部分的对应视图。
    • 5. 发明授权
    • Processing medical image information to detect anatomical abnormalities
    • 处理医学图像信息以检测解剖异常
    • US07672494B2
    • 2010-03-02
    • US11419980
    • 2006-05-23
    • Takeshi DoiWei Zhang
    • Takeshi DoiWei Zhang
    • G06K9/00A61B6/04
    • G06T7/0012G06T2207/30068
    • A method, system, and related computer program products are provided for processing a medical image of a body part according to a computer-aided detection (CAD) algorithm, the medical image having an image border, the body part comprising imaged tissue appearing inside the image border and outlying tissue not appearing in the medical image, wherein likely anatomical abnormalities in the outlying tissue near the imaged tissue border are detected by the CAD algorithm. In one example, the detected likely abnormalities in the outlying tissue are located within a first distance from the imaged tissue border, wherein the first distance corresponds to a spatial ambit of a neighborhood-based feature computed by the CAD algorithm.
    • 提供了一种根据计算机辅助检测(CAD)算法来处理身体部位的医学图像的方法,系统和相关的计算机程序产品,所述医学图像具有图像边界,所述身体部分包括出现在内部的成像组织 图像边界和不存在于医学图像中的外围组织,其中通过CAD算法检测在成像组织边界附近的外围组织中可能的解剖异常。 在一个示例中,所检测到的外围组织中可能的异常位于距成像组织边界的第一距离内,其中第一距离对应于由CAD算法计算的基于邻域的特征的空间范围。
    • 9. 发明申请
    • Angiogenesis inhibitor
    • 血管生成抑制剂
    • US20070043078A1
    • 2007-02-22
    • US10574972
    • 2004-10-08
    • Takeshi DoiMasahiro Tamura
    • Takeshi DoiMasahiro Tamura
    • A61K31/4545
    • A61K31/4468A61K31/444A61K31/4545C07D401/14
    • The present invention relates to a prophylactic or therapeutic agent against a disease or pathological condition caused by angiogenesis, comprising, as an active ingredient, a cyclic amine compound represented by the general formula (1): wherein R1, R2, and R3 each independently represent a hydrogen atom, a halogen atom, a hydroxy group, an alkyl group, a halogen-substituted alkyl group, an alkoxy group, an alkylthio group, a carboxyl group, an alkoxycarbonyl group, or an alkanoyl group; W1 and W2 each independently represent N or CH; X represents O, NR4, CONR4, or NR4CO; R4 represents a hydrogen atom, an alkyl group, an alkenyl group, an alkynyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted heteroaryl group, a substituted or unsubstituted aralkyl group, or a substituted or unsubstituted heteroaralkyl group; and l, m, and n each represent a number of 0 or 1, or a salt thereof, or a solvate thereof.
    • 本发明涉及由血管发生引起的疾病或病理状况的预防或治疗剂,其包含作为活性成分的通式(1)表示的环胺化合物:其中R 1, R 2,R 3和R 3各自独立地表示氢原子,卤素原子,羟基,烷基,卤素取代的烷基,烷氧基 ,烷硫基,羧基,烷氧基羰基或烷酰基; W 1和W 2各自独立地表示N或CH; X表示O,NR 4,CONR 4或NR 4 CO; R 4表示氢原子,烷基,烯基,炔基,取代或未取代的芳基,取代或未取代的杂芳基,取代或未取代的芳烷基或取代的 或未取代的杂芳烷基; 和l,m和n各自表示0或1的数,或其盐或其溶剂合物。
    • 10. 发明授权
    • Variable resistor
    • US06628193B2
    • 2003-09-30
    • US09887677
    • 2001-06-20
    • Takeshi DoiYukinori Ueda
    • Takeshi DoiYukinori Ueda
    • H01C1032
    • H01C10/32
    • A thin-thickness variable resistor is provided, which is capable of stabilizing electrical connection between metallic terminals and a resistor by increasing the holding strength for a second terminal by a substrate while preventing the bending strain during the bending work from spreading to a conductive portion conductive to the resistor. A variable resistor comprises a substrate, metallic terminals formed in the substrate by insert-molding, and a slider sliding on a resistor formed on the substrate, wherein the slider is rotatably attached by crimping an eyelet formed in a first metallic terminal. External-connecting portions of the metallic terminals are extended from the bottom portion of the substrate to be bent upwardly along sides of the substrate. Anchor portions to be embedded into the substrate are unitarily formed in the vicinity of the conductive portions of the second metallic terminals conductive to the resistor and between the conductive portions of the second metallic terminals and the external connection portions thereof.