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    • 3. 发明授权
    • Absorption cool-warm water machine and method for controlling the same
    • 吸热冷热水机及其控制方法
    • US5865035A
    • 1999-02-02
    • US881078
    • 1997-06-24
    • Hiroshi KojimaMakoto NakamuraMasaru EderaMasahiro Oka
    • Hiroshi KojimaMakoto NakamuraMasaru EderaMasahiro Oka
    • F25B15/00F25B15/06F25B49/04
    • F25B49/043F25B15/008F25B15/06F25B2315/001Y02B30/62
    • An absorption cool-water machine including a high quality fuel system and an exhaust heat utility system and apparatus and method for controlling the same is described in which the control has improved effectiveness in preventing the occurrence of crystallization in the exhaust heat exchanger tubing and/or corrosion resulting from an increase in high temperature regenerator temperatures and to otherwise prevent the production of unavailable refrigerant, save energy in an exhaust heat charge mode of operation, and to insure refrigerating ability even when exhaust water temperatures are low without reducing the effectiveness of the machine. In the described organization, a determination is made of the operative state of the exhaust heat utility system and adjustments are automatically made in supremum limiters for controlling the degree of opening of throttle valves for adjusting the supply of fuel and combustion air to the high quality fuel system that supplies heat to the high temperature regenerator.
    • 描述了包括高质量燃料系统和排气热利用系统的吸收式冷水机及其控制装置和方法,其中该控制具有改进的效果,以防止在排气热交换器管道中发生结晶和/或 由于高温再生器温度升高而导致的腐蚀,否则可能会阻止生产不可用的制冷剂,从而节省了排气热量运行方式的能量,并且即使在排水温度低的情况下也能确保制冷能力,而不会降低机器的有效性 。 在所述的组织中,确定排气热利用系统的操作状态,并且在上限限制器中自动进行调节,以控制用于调节燃料和燃烧空气供应给高质量燃料的节流阀的打开程度 向高温再生器供热的系统。
    • 4. 发明授权
    • Absorption cool-warm water machine and method for controlling the same
    • 吸热冷热水机及其控制方法
    • US5678414A
    • 1997-10-21
    • US592292
    • 1996-04-09
    • Hiroshi KojimaMakoto NakamuraMasaru EderaMasahiro Oka
    • Hiroshi KojimaMakoto NakamuraMasaru EderaMasahiro Oka
    • F25B15/00F25B15/06F25B49/04
    • F25B49/043F25B15/008F25B15/06F25B2315/001Y02B30/62
    • An absorption cool-water machine including a high quality fuel system and an exhaust heat utility system and apparatus and method for controlling the same is described in which the control has improved effectiveness in preventing the occurrence of crystallization in the exhaust heat exchanger tubing and/or corrosion resulting from an increase in high temperature regenerator temperatures and to otherwise prevent the production of unavailable refrigerant, save energy in an exhaust heat charge mode of operation, and to insure refrigerating ability even when exhaust water temperatures are low without reducing the effectiveness of the machine. In the described organization, a determination is made of the operative state of the exhaust heat utility system and adjustments are automatically made in supremum limiters for controlling the degree of opening of throttle valves for adjusting the supply of fuel and combustion air to the high quality fuel system that supplies heat to the high temperature regenerator.
    • PCT No.PCT / JP95 / 01151 Sec。 371日期:1996年4月9日 102(e)日期1996年4月9日PCT Filed 1995年6月9日PCT Pub。 第WO95 / 34789号公报 日期1995年12月21日描述了一种包括高质量燃料系统和排气热利用系统的吸收式冷水机及其控制装置和方法,其中控制具有改善的效果,防止在排气热中发生结晶 交换器管道和/或由高温再生器温度升高引起的腐蚀,并且否则防止生产不可用的制冷剂,节省能量进入排气加热运行模式,并且即使在排水温度低的情况下也确保制冷能力而不减少 机器的有效性。 在所述的组织中,确定排气热利用系统的操作状态,并且在上限限制器中自动进行调节,以控制用于调节燃料和燃烧空气供应给高质量燃料的节流阀的打开程度 向高温再生器供热的系统。
    • 8. 发明授权
    • Graft-versus-host disease predicting marker and use thereof
    • 移植物抗宿主病预测标记及其用途
    • US08603754B2
    • 2013-12-10
    • US13204799
    • 2011-08-08
    • Akira ShibuyaHiroshi Kojima
    • Akira ShibuyaHiroshi Kojima
    • G01N33/53
    • G01N33/573A61K39/3955A61K2039/505C07K16/2803G01N2333/91245G01N2800/245
    • A test method that provides data useful in predicting the probability of onset of acute graft-versus-host disease (GVHD) is described along with a kit for performing the method, and a pharmaceutical preparation and a molecular targeted therapy for treating or preventing GVHD. The test method includes measuring the blood DNAM-1 concentration of a patient of hematopoietic stem cell transplantation from bone marrow or the like over a period after the transplantation to provide data concerning the transition of the concentration to an abnormally high level deviating from the normal range, whereby the probability of the development of acute graft-versus-host disease is predicted, the risk of the development is estimated, or therapeutic effects after the development are evaluated. Concerning the molecular targeted therapy and pharmaceutical preparation used therefor wherein blood DNAM-1 of a GVHD patient or a graft recipient that is a possible patient is used as a target molecule, GVHD is treated or prevented by administering an anti-DNAM-1 antibody that is a neutralizing antibody.
    • 描述了提供用于预测急性移植物抗宿主病(GVHD)发病概率的数据的测试方法以及用于进行该方法的试剂盒以及用于治疗或预防GVHD的药物制剂和分子靶向治疗。 测试方法包括在移植后的一段时间内测量来自骨髓等的造血干细胞移植患者的血液DNAM-1浓度,以提供关于浓度向偏离正常范围的异常高水平转变的数据 预测急性移植物抗宿主病发展的可能性,估计发展的风险,或发展后的治疗效果。 关于其中使用的分子靶向治疗和药物制剂,其中GVHD患者的血液DNAM-1或作为可能患者的移植物接受体用作靶分子,通过施用抗-DNAM-1抗体来治疗或预防GVHD, 是中和抗体。