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    • 3. 发明授权
    • Evaluation method and screening method for substance having action of activating/suppressing innate immunity, agent and food product for activating/suppressing innate immune mechanism and method for producing the same
    • 用于激活/抑制先天免疫的作用的物质的评估方法和筛选方法,用于激活/抑制先天免疫机制的药剂和食品及其制备方法
    • US08313779B2
    • 2012-11-20
    • US12595245
    • 2008-04-10
    • Kazuhisa SekimizuHiroshi Hamamoto
    • Kazuhisa SekimizuHiroshi Hamamoto
    • A61K35/12A61K35/34A61K49/00C12Q1/02
    • A61K36/18A01K2267/0387A23L33/00A23L33/10A61K35/74A61K38/17C12N15/8509C12N2710/14043G01N33/5082
    • It is intended to provide an evaluation method and a screening method capable of eliminating a substance that disturbs in vivo kinetics in an individual and capable of simply and easily searching a substance having an action of activating/suppressing an innate immune mechanism without being affected by LPS derived from bacteria, which can be contaminated during the search, as well as a drug and a food for activating/suppressing the innate immune mechanism, and methods of producing the same. The present invention provides a method of evaluating or screening the substance having the action of activating/suppressing the innate immune mechanism using a muscular contraction of an organism having the innate immune mechanism as an indicator, and methods of producing the drug and the food for activating/suppressing the innate immune mechanism. Also, an innate immunity activator and the food having the action of activating the innate immune mechanism containing the substance having the action of contracting the muscle of the organism having the innate immune mechanism, and an innate immunity suppressor and the food having the action of suppressing the innate immunity containing the substance having the action of suppressing the contraction of the muscle of the organism having the innate immune mechanism are provided.
    • 旨在提供能够消除妨碍个体的体内动力学的物质的能够简单且容易地搜索具有激活/抑制先天免疫机制的物质而不受LPS影响的物质的评价方法和筛选方法 来源于可以在搜索期间被污染的细菌,以及用于激活/抑制先天免疫机制的药物和食物,以及其生产方法。 本发明提供一种使用具有先天免疫机制的生物体的肌肉收缩作为指标来评价或筛选具有激活/抑制先天免疫机制的作用的物质的方法,以及制备药物和活化食物的方法 /抑制先天免疫机制。 此外,先天性免疫激活剂和具有激活含有具有收缩具有先天免疫机制的生物体肌肉作用的物质的先天免疫机制的作用的食物,以及先天性免疫抑制剂和具有抑制作用的食物 提供含有具有抑制具有先天免疫机制的生物体的肌肉收缩作用的物质的先天免疫力。
    • 5. 发明授权
    • Electronic balance
    • 电子天平
    • US07917329B2
    • 2011-03-29
    • US12162049
    • 2007-09-03
    • Hiroshi Hamamoto
    • Hiroshi Hamamoto
    • G06F15/00G01G19/40
    • G01G23/37
    • An electronic balance 1 is provided with a measured weight storage controlling portion 33 for storing measured weight in sequence, a measuring mode storing portion 42 for storing a number of measuring modes where different averaging parameters are preset, an input portion for a measuring mode 72 which carries out an input operation for selecting one measuring mode from among a number of measuring modes, and an average weight display controlling portion 31 for calculating the average weight by averaging the number of measured weight on the basis of the averaging parameter in the measuring mode and displays the average weight in a display portion 60, and is characterized in that the electronic balance is further provided with an input portion 71 for making a modification which carries out an input operation for making a modification on the averaging parameter in the selected measuring mode, and the average weight display controlling portion 31 calculates the average weight by averaging the number of measured weight on the basis of the averaging parameter where a modification is made and displays the average weight in the display portion 60.
    • 电子天平1设置有用于按顺序存储测量重量的测量重量存储控制部分33,用于存储预设不同平均参数的多个测量模式的测量模式存储部分42,用于测量模式72的输入部分 执行从多个测量模式中选择一个测量模式的输入操作,以及平均重量显示控制部分31,用于基于测量模式中的平均参数来平均测量重量的数量来计算平均重量;以及 在显示部分60中显示平均重量,其特征在于,电子天平还设置有用于进行修改的输入部分71,其进行用于对所选择的测量模式中的平均参数进行修改的输入操作, 平均重量显示控制部31通过求平均值t来计算平均权重 基于进行修改的平均参数的测量重量的数量,并在显示部分60中显示平均重量。
    • 6. 发明申请
    • ELECTRONIC BALANCE
    • 电子平衡
    • US20090024960A1
    • 2009-01-22
    • US12280710
    • 2006-03-23
    • Hiroshi Hamamoto
    • Hiroshi Hamamoto
    • G06F3/048
    • G01G23/00
    • In the electronic balance according to the present invention, in the menu list in which basic menu list information wherein predetermined many menu items are tree-structured and user menu list information stored in a nonvolatile memory when a user registers at will a calculation function or other functions which the user frequently uses are incorporated, it is possible to select an intended menu item, by moving in the same layer and moving to the lower layer step by step in accordance with a predetermined key operation. Since the setting/cancellation of the menu item, e.g. the function 8, that the user often uses is provided in the lower layer of my menu which has a high priority, it is possible to select it with a small number of key operations compared to the case where the selection is performed by following the tree structure step by step, e.g. from the menu group 2 to the function 8. This increases the efficiency of the operation, and since the operation is simple, the user can operate without referring to an operation manual. Since no change of the order or the like occurs in the basic menu list other than the user menu list 29, it is possible to perform the selection of the menu item in such a list with a conventional operation.
    • 在根据本发明的电子天平中,在菜单列表中,其中预定许多菜单项是树形结构的基本菜单列表信息和用户在登记时存储在非易失性存储器中的用户菜单列表信息将具有计算功能或其他 结合使用者经常使用的功能,可以通过在同一层中移动并根据预定的键操作逐步移动到下层来选择预期的菜单项。 由于菜单项的设置/取消,例如, 用户经常使用的功能8被提供在具有高优先级的菜单的下层中,与通过跟随树进行选择的情况相比,可以用少量的键操作来选择它 结构一步一步,例如 从菜单组2到功能8.这增加了操作的效率,并且由于操作简单,用户可以在不参考操作手册的情况下操作。 由于在用户菜单列表29以外的基本菜单列表中没有发生顺序改变等,所以可以用常规操作来执行这种列表中的菜单项目的选择。
    • 7. 发明授权
    • Weight measuring device
    • 重量测量装置
    • US07395183B2
    • 2008-07-01
    • US11115018
    • 2005-04-26
    • Hiroshi Hamamoto
    • Hiroshi Hamamoto
    • G01G19/00G01G11/00
    • G01G23/01
    • A weight measuring device comprises a load detecting section for constantly detecting a load value (W) of a sample placed on a measuring pan; a moving average processing section for calculating a moving average (Wa) of the detected load value (W); a load changing rate calculating section for calculating a load changing rate per unit time (Wb) of the detected load value (W); a storage section for storing a first load change threshold (Wr1), a second load change threshold (Wr2) which is smaller than the first load change threshold (Wr1) and a load changing rate threshold per unit time (Wt); a determining section for determining whether a moving average processing should be executed; and a weight conversion processing section for calculating a weight of the sample from the load (W) or the moving average (Wa).
    • 一种重量测量装置,包括负载检测部分,用于不断地检测放置在测量盘上的样品的载荷值(W); 移动平均处理部,用于计算检测到的负载值(W)的移动平均值(Wa); 负载变化率计算部分,用于计算检测到的负载值(W)的每单位时间的负载变化率(Wb); 用于存储小于第一负载变化阈值(Wr 1)的第一负载变化阈值(Wr 1),第二负载变更阈值(Wr2)和每单位时间负载变化率阈值(Wt)的存储部; 确定部分,用于确定是否应执行移动平均处理; 以及权重转换处理部分,用于根据负载(W)或移动平均值(Wa)计算样本的权重。
    • 8. 发明授权
    • Electronic balance
    • 电子天平
    • US08604939B2
    • 2013-12-10
    • US12307917
    • 2007-07-24
    • Tsuyoshi SatohHiroshi HamamotoKoji Hattori
    • Tsuyoshi SatohHiroshi HamamotoKoji Hattori
    • G08B21/00
    • G01G23/3707G01G19/62G01G23/365G01G23/3721
    • An electronic balance for clearly indicating the degree of precision to a target weight value is provided. A signal converter (2) converts an electronic signal outputted from a weight detecting circuit (1) into a digital signal. A computing section (3) converts the digital signal into a measured weight value Wx, reads a target weight value Wd (=W0±ΔW) determined by a target center value W0 and a tolerance ±ΔW inputted from a weight setting unit (5) through an interface (4), compares the measured weight value Wx and the target weight value Wd to obtain a difference, and transmits a signal for flashing or turning on the character display corresponding to the difference and the measured weight value Wx to a display unit (6) and transmits a sound signal to a buzzer (7).
    • 提供了用于清楚地指示目标重量值的精度的电子天平。 信号转换器(2)将从权重检测电路(1)输出的电子信号转换为数字信号。 计算部分(3)将数字信号转换成测量的权重值Wx,读取由目标中心值W0确定的目标权重值Wd(= W0±ΔW)和从权重设定单元(5)输入的公差±ΔW, 通过接口(4),将测量的重量值Wx和目标重量值Wd进行比较以获得差值,并将与差异相对应的字符显示的闪烁或开启信号和测量的权重值Wx发送到显示单元 (6),并将声音信号发送到蜂鸣器(7)。
    • 10. 发明授权
    • Electronic balance with windshield
    • 挡风玻璃电子天平
    • US07544903B2
    • 2009-06-09
    • US11815525
    • 2006-02-03
    • Hiroshi HamamotoKunio Shimauchi
    • Hiroshi HamamotoKunio Shimauchi
    • G01G21/28
    • G01G21/30G01G21/286G01G23/48
    • [Problems] To obtain a stable measurement result in both a measuring-out mode and normal mode, and to obtain a weight value eliminating the influence of convection in the windshield.[Means for Solving Problems] An electronic balance with a windshield 51, the windshield surrounding a measuring pan 53 and having an openable/closable door 52, for averaging measurement data in a response time and obtaining a weight value based on it, the electronic balance including: a door open/close detection sensor 3 for detecting an open/close of the door 52; and a mode changer for switching the measurement mode between a measuring-out mode in which the response time is relatively short when the door 52 is open, and a normal mode in which the response time is relatively long when the door 52 is closed. In addition, in a convection time measurement mode, a convection time period since the door is closed with no sample on the measuring pan 53 until the fluctuation of the measurement data is settled down within a predetermined range is measured and memorized. After the memorized convection time has passed after a sample was put on the measuring pan 53 and the door 52 was closed in a normal measurement mode, the measurement data is averaged in a predetermined response time and the weight value is calculated.
    • [问题]为了在测量模式和正常模式两者中获得稳定的测量结果,并获得减轻挡风玻璃对流影响的重量值。 解决问题的手段具有挡风玻璃51的电子天平,挡风玻璃围绕测量盘53并具有可打开/关闭的门52,用于在响应时间内对测量数据进行平均并基于此得到重量值,电子天平 包括:用于检测门52的打开/关闭的门打开/关闭检测传感器3; 以及用于在门52打开时响应时间相对短的测量模式和门52关闭时响应时间相对较长的正常模式切换测量模式的模式更换器。 此外,在对流时间测量模式中,测量和记忆自从门在关闭测量盘53上没有样本的对流时间段,直到测量数据的波动在预定范围内稳定为止。 在将样品放在测量盘53上并且门52以正常测量模式关闭之后经过存储的对流时间之后,在预定响应时间内对测量数据进行平均,并计算重量值。