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    • 1. 发明申请
    • On-chip bioassay method and kit
    • 片上生物测定方法和试剂盒
    • US20060246416A1
    • 2006-11-02
    • US10566861
    • 2004-02-04
    • Hirofumi TaniTamio KamidateKoji Maehana
    • Hirofumi TaniTamio KamidateKoji Maehana
    • C12Q1/00C12Q1/68C12M1/34
    • B01L3/5025B01J2219/00317B01J2219/00743B01L3/5027B01L3/502707B01L2300/0864B01L2300/0874B01L2300/0887C12Q1/025C40B60/14G01N2500/10
    • The present invention provides an on-chip bioassay system which reduces preoperations including culture, and is highly versatile and capable of conducting high throughput analyses. A microfluidic chip for introducing a cell is fixed on the undersurface of a microporous chip composed of a substrate through which a plurality of micropores arranged like a lattice penetrate, and thus forming a plurality of microchannels between the microporous chip and the microfluidic chip for introducing a cell; a suspended cell is poured into a micropore through the channel; then a microfluidic chip for introducing a test substance is fixed on the upper surface of the microporous chip such that its plurality of microchannels for introducing a test substance are placed in a direction perpendicular to the channels for introducing a cell, and thus forming a plurality of microchannels between the microporous chip and the microfluidic chip for introducing a test substance; a test substance is poured through the channel and brought into contact with the cell in a micropore of the microporous chip; a level of effect of the test substance on the cell is detected in situ after a predetermined time, or at a predetermined time interval.
    • 本发明提供了一种降低包括培养在内的预操作的片上生物测定系统,并且是高通用性的并且能够进行高通量分析。 用于引入电池的微流体芯片固定在由基底构成的微孔芯片的下表面上,多个微孔排列成晶格穿过该基底,从而在微孔芯片和微流体芯片之间形成多个微通道,用于引入 细胞; 将悬浮的细胞通过通道倒入微孔中; 然后将用于引入测试物质的微流体芯片固定在微孔芯片的上表面上,使得用于引入测试物质的多个微通道被放置在垂直于用于引入电池的通道的方向上,从而形成多个 微孔芯片和用于引入测试物质的微流体芯片之间的微通道; 将测试物质通过通道注入并与微孔芯片的微孔中的细胞接触; 在预定时间之后或以预定时间间隔在原位检测测试物质对细胞的影响程度。
    • 2. 发明申请
    • Recording and replay device
    • 记录和重播设备
    • US20070269186A1
    • 2007-11-22
    • US11802342
    • 2007-05-22
    • Hirofumi Tani
    • Hirofumi Tani
    • H04N7/00
    • G11B27/329G11B27/034G11B2220/2545G11B2220/2562
    • This recording and replay device includes a replay means which reads in and replays binary data from a medium upon which a binary file which includes binary data and index data is stored. This medium also stores a table in which representative time points and second addresses are held in mutual correspondence. Moreover, this recording and replay device includes an address detection means which, when a replay elapsed time is designated, refers to this table, and extracts that one of the second addresses which corresponds to that one of the representative time points which, while being before the elapsed time for replay, is closest thereto. And this address detection means searches sequentially through the index data from the second address which has been extracted, and detects that one of the first addresses which corresponds to the elapsed time for replay.
    • 该记录和重放装置包括重放装置,其从存储有二进制数据和索引数据的二进制文件的介质读入和重放二进制数据。 该介质还存储有代表时间点和第二地址保持相互对应的表格。 此外,该记录和重播装置包括一个地址检测装置,当指定重播经过时间时,参考该表,并且提取与之前的代表时间点中的那一个对应的第二地址中的哪一个 重播的经过时间最接近。 并且该地址检测装置依次检索来自已经提取的第二地址的索引数据,并且检测与经过的重放时间对应的第一地址中的一个地址。
    • 5. 发明授权
    • Recording method for rewritable optical disk
    • 可重写光盘的记录方法
    • US06735156B2
    • 2004-05-11
    • US10015649
    • 2001-12-17
    • Hirofumi Tani
    • Hirofumi Tani
    • G11B700
    • G11B20/18G11B20/1217G11B2020/1221G11B2020/1288
    • When an error has occurred during the recording of an optical disk, the track recording system is changed from a variable-length packet write system to a fixed-length packet write system employing an arbitrary length (step S2). A check is performed to determine whether before the error occurred the number of blocks used for recording was equal to or greater than 300, which is the minimum block length for one track (step S4). When at least 300 blocks have not been used for recording, by using as a recording unit a fixed-length packet having the arbitrary length, the dummy data are continuously recorded until the used block count reaches 300 (steps S5 to S7). Thus, when an error occurs during the recording of dummy data (Yes at step S6), one fixed-length packet is added (step S8) and the recording of dummy data is continued.
    • 在记录光盘期间发生错误时,轨道记录系统从可变长度分组写入系统改变为采用任意长度的固定长度分组写入系统(步骤S2)。 执行检查以确定在错误发生之前是否用于记录的块的数量等于或大于300,这是一个轨道的最小块长度(步骤S4)。 当至少有300个块未被用于记录时,通过使用具有任意长度的固定长度分组作为记录单元,连续记录虚拟数据,直到所使用的块计数达到300(步骤S5至S7)为止。 因此,当在伪数据的记录期间发生错误时(步骤S6为“是”),添加一个固定长度的分组(步骤S8),继续记录虚拟数据。