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1. 发明授权

US6165749A Plasmid 失效
标题翻译：质粒
公开(公告)号：US6165749A
公开(公告)日：2000-12-26
申请号：US952089
申请日：1997-11-10
申请人： Hiroaki Sagawa , Harumi Ueno , Atsushi Oshima , Ikunoshin Kato
发明人： Hiroaki Sagawa , Harumi Ueno , Atsushi Oshima , Ikunoshin Kato
IPC分类号： C12N15/09 , C12N1/21 , C12N9/10 , C12N9/16 , C12N9/22 , C12N15/55 , C12N15/69 , C12R1/19 , C12P21/06
CPC分类号： C12N15/69 , C12N9/1007 , C12N9/22
摘要： A plasmid vector characterized by comprising a promoter sequence that can be recognized by an RNA polymerase which is not inherent in a host and that controls the expression of desired genes and a replication origin that increases the number of copies under the induction by exogenous factors; methods for expression and isolation of target genes by using the vector; a polypeptide having the activity of an AccIII restriction endonuclease; and a DNA encoding the polypeptide. The invention provides for the first time a plasmid vector which can introduce an exogenous desired gene encoding proteins which are lethal or harmful to hosts into the hosts, a method for efficiently expressing the proteins by using the vector, and also a method for permitting a restriction endonuclease gene constituting a restriction-modification system to be isolated even in the absence of a modification enzyme gene, which has been difficult in the prior arts.
摘要翻译： PCT No.PCT / JP97 / 00748 Sec。 371日期：1997年11月10日 102（e）日期1997年11月10日PCT 1997年3月10日PCT公布。第WO97 / 34006号公报日期1997年9月18日一种质粒载体，其特征在于包含可由RNA聚合酶识别的启动子序列，其不是宿主中固有的并且控制所需基因的表达和增加诱导下拷贝数的复制起点由外生因素; 通过使用载体表达和分离靶基因的方法; 具有AccIII限制性内切核酸酶活性的多肽; 和编码该多肽的DNA。本发明首次提供能够将编码对宿主具有致死性或有害性的蛋白质的外源性所需基因导入宿主的质粒载体，使用该载体有效表达蛋白质的方法，以及允许限制的方法构成即使在不存在修饰酶基因的情况下分离的限制性修饰系统的核酸内切酶基因，这在现有技术中是困难的。

2. 发明授权

US06770481B1 Gene isolation method 失效
标题翻译：基因分离方法
公开(公告)号：US06770481B1
公开(公告)日：2004-08-03
申请号：US09690885
申请日：2000-10-18
申请人： Hiroaki Sagawa , Harumi Ueno , Atsushi Oshima , Ikunoshin Kato
发明人： Hiroaki Sagawa , Harumi Ueno , Atsushi Oshima , Ikunoshin Kato
IPC分类号： C12N1563
CPC分类号： C12N15/69 , C12N9/1007 , C12N9/22
摘要： A plasmid vector characterized by comprising a promoter sequence that can be recognized by an RNA polymerase which is not inherent in a host and that controls the expression of desired genes and a replication origin that increases the number of copies under the induction by exogenous factors; methods for expression and isolation of target genes by using the vector; a polypeptide having the activity of an AccIII restriction endonuclease; and a DNA encoding the polypeptide. The invention provides for the first time a plasmid vector which can introduce an exogenous desired gene encoding proteins which are lethal or harmful to hosts into the hosts, a method for efficiently expressing the proteins by using the vector, and also a method for permitting a restriction endonuclease-gene constituting a restriction-modification system to be isolated even in the absence of a modification enzyme gene, which has been difficult in the prior arts.
摘要翻译：一种质粒载体，其特征在于包含可以通过RNA聚合酶识别的启动子序列，其不是宿主中固有的并且控制所需基因的表达和复制起点，其通过外源因子诱导的拷贝数增加; 通过使用载体表达和分离靶基因的方法; 具有AccIII限制性内切核酸酶活性的多肽; 和编码该多肽的DNA。本发明首次提供能够将编码对宿主具有致死性或有害性的蛋白质的外源性所需基因导入宿主的质粒载体，使用该载体有效表达蛋白质的方法，以及允许限制的方法即使在不存在修饰酶基因的情况下也构成即将分离的限制性修饰系统的内切核酸酶 - 基因，这在现有技术中是困难的。

3. 发明授权

US5684146A DNA coding for variable region to human influenza A type virus 失效
标题翻译：编码可变区到人流感A型病毒的DNA
公开(公告)号：US5684146A
公开(公告)日：1997-11-04
申请号：US401908
申请日：1995-03-10
申请人： Yoshinobu Okuno , Atsushi Oshima , Hirofumi Yoshioka , Takashi Takabatake , Ikunoshin Kato
发明人： Yoshinobu Okuno , Atsushi Oshima , Hirofumi Yoshioka , Takashi Takabatake , Ikunoshin Kato
IPC分类号： G01N33/53 , A61K39/145 , A61P31/12 , A61P31/16 , C07K14/705 , C07K16/00 , C07K16/10 , C12N1/21 , C12N15/09 , C12N15/13 , C12P21/08 , C12R1/19 , C12R1/91 , G01N33/569 , G01N33/577 , C07H21/04 , C07K16/08 , C12N5/12
CPC分类号： C07K16/1018
摘要： An isolated DNA is provided coding for the variable region of an anti-human influenza A type virus antibody having the following characteristics: (a) specifically binds to the stem region of haemaggulutinin molecule of H1N1 and H2N2 subtypes of human influenza A type virus but does not specifically bind to the stem region of haemaggulutinin molecule of H3N2 subtype; and (b) has a neutralization activity for the H1N1 and H2N2 subtypes of human influenza A type virus but no neutralization activity for the H3N2 subtype.
摘要翻译：提供了分离的DNA，其编码具有以下特征的抗人流感A型病毒抗体的可变区：（a）特异性结合人流感A型病毒的H1N1和H2N2亚型的血红蛋白分子的茎区，但是不具体结合H3N2亚型的血红蛋白分子的茎区; 和（b）对于甲型流感甲型H1N1和H2N2亚型具有中和活性，但H3N2亚型没有中和活性。

4. 发明授权

US08692590B2 Capacitive load drive circuit, liquid injector, and medical device 有权
标题翻译：电容负载驱动电路，液体注射器和医疗器械
公开(公告)号：US08692590B2
公开(公告)日：2014-04-08
申请号：US13295876
申请日：2011-11-14
申请人： Atsushi Oshima
发明人： Atsushi Oshima
IPC分类号： H03K3/00
CPC分类号： H03K7/08 , H03K17/166
摘要： A drive waveform signal is pulse-modulated and a modulated signal is generated, the obtained modulated signal is power-amplified, and then, a drive signal is demodulated using a low pass filter. Thus obtained drive signal is negatively fed back, and thereby, the resonance peak of the low pass filter is suppressed. In this regard, by bringing gain in a wider frequency domain to take a fixed value or more, a drive signal having a voltage exceeding a power supply voltage may be stably generated.
摘要翻译：驱动波形信号被脉冲调制并产生调制信号，所获得的调制信号被功率放大，然后使用低通滤波器对驱动信号进行解调。这样获得的驱动信号被反馈，从而抑制低通滤波器的谐振峰值。在这方面，通过使更宽的频域的增益达到固定值以上，可以稳定地产生电压超过电源电压的驱动信号。

5. 发明授权

US08690281B2 Capacitive load driving circuit, liquid ejecting apparatus, and medical apparatus 有权
标题翻译：电容负载驱动电路，液体喷射装置和医疗装置
公开(公告)号：US08690281B2
公开(公告)日：2014-04-08
申请号：US13295971
申请日：2011-11-14
申请人： Atsushi Oshima , Kunio Tabata , Hiroyuki Yoshino , Noritaka Ide
发明人： Atsushi Oshima , Kunio Tabata , Hiroyuki Yoshino , Noritaka Ide
IPC分类号： B41J29/38
CPC分类号： B41J2/04588 , B41J2/04541 , B41J2/04573 , B41J2/04581
摘要： A modulated signal is generated by performing pulse modulation of a drive waveform signal that is a reference for a drive signal to be applied to a capacitive load, and the drive signal is generated by performing power amplification of the acquired modulated signal and then smoothing the power-amplified modulated signal. Then, negative feedback of the drive signal applied to the capacitive load is applied to the drive waveform signal that is the reference for the drive signal. At this time, a predetermined analog compensation process for smoothing gain characteristics in a frequency band included in the drive signal is performed for the drive signal, then the acquired signal is converted into a digital signal, and negative feedback of the digital signal is applied to the drive waveform signal.
摘要翻译：通过对驱动信号进行脉冲调制来生成调制信号，该驱动波形信号是作为对电容性负载的驱动信号的基准，通过对所获取的调制信号进行功率放大，然后使功率平滑化来生成驱动信号放大调制信号。然后，施加到电容性负载的驱动信号的负反馈被施加到作为驱动信号的参考的驱动波形信号。此时，对驱动信号执行用于平滑驱动信号中包括的频带中的增益特性的预定的模拟补偿处理，然后将获取的信号转换为数字信号，并将数字信号的负反馈应用于驱动波形信号。

6. 发明授权

US08336979B2 Liquid jetting device 有权
标题翻译：液体喷射装置
公开(公告)号：US08336979B2
公开(公告)日：2012-12-25
申请号：US12624206
申请日：2009-11-23
申请人： Atsushi Oshima
发明人： Atsushi Oshima
IPC分类号： B41J29/38
CPC分类号： B41J29/38 , B41J2/04541 , B41J2/04581 , B41J2/0459 , B41J2/04593 , B41J2/04596
摘要： A liquid jetting device includes a plurality of nozzles. A driving signal generated by a driving signal generating section is applied to a charge-discharge actuator in correspondence with each nozzle to jet liquid from the nozzle. A charging source potential preliminary adjusted wave-form signal is pulse modulated and electrically amplified using a charging source potential transistor pair connected in a push-pull configuration, and output by a ripple filter to a collector of a charge-use transistor of the driving signal generating section to make a preliminary adjustment to the charging source potential for the driving signal generating section.
摘要翻译：液体喷射装置包括多个喷嘴。由驱动信号产生部产生的驱动信号被施加到与每个喷嘴对应的充放电致动器以从喷嘴喷射液体。充电源电位初步调整波形信号被脉冲调制并使用以推挽配置连接的充电源电位晶体管对进行电放大，并由纹波滤波器输出到驱动信号的充电用晶体管的集电极对所述驱动信号生成部的充电源电位进行初步调整。

7. 发明授权

US08313170B2 Fluid ejection device 有权
标题翻译：流体喷射装置
公开(公告)号：US08313170B2
公开(公告)日：2012-11-20
申请号：US12605466
申请日：2009-10-26
申请人： Kunio Tabata , Nobuaki Azami , Hiroyuki Yoshino , Shinichi Miyazaki , Atsushi Oshima , Noritaka Ide
发明人： Kunio Tabata , Nobuaki Azami , Hiroyuki Yoshino , Shinichi Miyazaki , Atsushi Oshima , Noritaka Ide
IPC分类号： B41J2/045 , B41J29/38
CPC分类号： B41J2/0459 , B41J2/04548 , B41J2/04573 , B41J2/04581 , B41J2/04588
摘要： A fluid ejection device configured to eject fluid from an ejection port includes a driving element that pressurizes the fluid and causes it to be ejected from the ejection port by being driven according to a voltage applied thereto. A driving voltage waveform selecting unit selects a driving voltage waveform to be applied to the driving element from among a plurality of types of the stored driving voltage waveforms. Power sources set the voltage to be outputted. A power source voltage determining unit determines voltages to be set to the power sources on the basis of the selected driving voltage waveform. A driving voltage waveform applying unit applies the selected driving voltage waveform to the driving element by setting the determined voltages to the power sources and connecting the power sources to the driving element while switching the same.
摘要翻译：构造成从喷射口喷射流体的流体喷射装置包括驱动元件，该驱动元件对流体进行加压，并通过根据施加到喷射口的电压被驱动而从喷射口喷射。驱动电压波形选择单元从多种存储的驱动电压波形中选择施加到驱动元件的驱动电压波形。电源设置要输出的电压。电源电压确定单元基于所选择的驱动电压波形确定要设置到电源的电压。驱动电压波形施加单元通过将确定的电压设置到电源并将电源连接到驱动元件而将所选择的驱动电压波形施加到驱动元件，同时切换该驱动电压波形。

8. 发明授权

US08262180B2 Liquid jet apparatus and printing apparatus 有权
标题翻译：液体喷射装置和打印装置
公开(公告)号：US08262180B2
公开(公告)日：2012-09-11
申请号：US11780379
申请日：2007-07-19
申请人： Atsushi Oshima , Kunio Tabata
发明人： Atsushi Oshima , Kunio Tabata
IPC分类号： B41J29/38
CPC分类号： B41J2/04593 , B41J2/04541 , B41J2/0455 , B41J2/04568 , B41J2/04581 , B41J2/04588 , B41J2/04596 , B41J29/38
摘要： A liquid jet apparatus includes a plurality of nozzles provided to a liquid jet head, an actuator provided corresponding to each of the nozzles, and drive unit that applies a drive signal to the actuator, wherein the drive unit includes drive waveform signal generation unit that generates a drive waveform signal providing a basis of a signal for controlling the operation of the actuator, modulator unit that pulse-modulates the drive waveform signal generated by the drive waveform signal generation unit, a digital power amplifier for power-amplifying the modulated signal, which is pulse-modulated by the modulator unit, a low-pass filter for smoothing the power-amplified and modulated signal power-amplified by the digital power amplifier and supplying the actuator with the power-amplified and modulated signal as the drive signal, and carrier frequency adjusting unit that adjusts a carrier frequency of the pulse modulation by the modulator unit in accordance with the number of the actuators to be driven.
摘要翻译：一种液体喷射装置，包括设置在液体喷射头上的多个喷嘴，与每个喷嘴对应的致动器，以及向致动器施加驱动信号的驱动单元，其中驱动单元包括产生提供用于控制致动器的信号的基础的驱动波形信号，对由驱动波形信号生成单元生成的驱动波形信号进行脉冲调制的调制器单元，用于对调制信号进行功率放大的数字功率放大器，由调制器单元进行脉冲调制，一个低通滤波器，用于对由数字功率放大器进行功率放大和功率放大的功率放大和调制信号进行平滑处理，并为执行器提供功率放大和调制信号作为驱动信号，载波频率调整单元，其根据所述致动器的数量调整所述调制器单元的脉冲调制的载波频率 rs被驱动。

9. 发明授权

US08240798B2 Head drive apparatus of inkjet printer and inkjet printer 有权
标题翻译：喷墨打印机和喷墨打印机的头驱动装置
公开(公告)号：US08240798B2
公开(公告)日：2012-08-14
申请号：US12161201
申请日：2007-01-17
申请人： Atsushi Oshima , Kunio Tabata , Osamu Shinkawa , Toshiyuki Suzuki , Tomoki Hatano
发明人： Atsushi Oshima , Kunio Tabata , Osamu Shinkawa , Toshiyuki Suzuki , Tomoki Hatano
IPC分类号： B41J29/38 , H03F3/38
CPC分类号： B41J2/04596 , B41J2/04541 , B41J2/04548 , B41J2/04568 , B41J2/04578 , B41J2/0458 , B41J2/04581 , B41J2/04588 , B41J2/04591 , B41J2/04595
摘要： A head drive device of an inkjet printer having a nozzles and corresponding actuators that jet liquid drops. A drive section that generates a drive signal to the actuators. The head drive device includes a drive waveform signal which is used as a reference of a signal to control drive of the actuators. A modulating section modulates a pulse of a drive waveform signal generated by the drive waveform generating system. A low pass filter smoothes a power-amplified modulated signal subjected to the power amplification by the digital power amplifier and supplies the signal as a drive signal to the actuators. A frequency characteristics adjusting section adjusts frequency characteristics of the low pass filter as a function of the number of the actuators.
摘要翻译：一种喷墨打印机的头驱动装置，其具有喷嘴和喷射液滴的相应致动器。驱动部分，用于产生驱动信号给致动器。头驱动装置包括驱动波形信号，该驱动波形信号用作用于控制致动器的驱动的信号的基准。调制部分调制由驱动波形发生系统产生的驱动波形信号的脉冲。低通滤波器对由数字功率放大器进行功率放大的功率放大调制信号进行平滑，并将该信号作为驱动信号提供给致动器。频率特性调整部分根据致动器的数量调节低通滤波器的频率特性。

10. 发明授权

US08172373B2 Fluid ejection device 有权
标题翻译：流体喷射装置
公开(公告)号：US08172373B2
公开(公告)日：2012-05-08
申请号：US12724816
申请日：2010-03-16
申请人： Atsushi Oshima , Shinichi Miyazaki , Kunio Tabata , Nobuaki Azami , Hiroyuki Yoshino , Noritaka Ide
发明人： Atsushi Oshima , Shinichi Miyazaki , Kunio Tabata , Nobuaki Azami , Hiroyuki Yoshino , Noritaka Ide
IPC分类号： B41J2/045
CPC分类号： B41J2/04581 , B41J2/04541 , B41J2/04555 , B41J2/0457
摘要： A fluid ejection device including, a drive element capable of storing a charge depending on a voltage applied to the drive element, a first capacitor, a second capacitor, and a power recovery module that recovers power from the drive element by connecting the first capacitor and the second capacitor to the drive element in series, wherein the power recovery module switches the first capacitor out of the in-series connection to further recover power from the drive element.
摘要翻译：一种流体喷射装置，包括：能够根据施加到驱动元件的电压存储电荷的驱动元件，第一电容器，第二电容器和功率恢复模块，其通过连接第一电容器和第二电容器来恢复来自驱动元件的电力; 所述驱动元件串联的所述第二电容器，其中所述功率恢复模块将所述第一电容器切换为所述串联连接，以进一步从所述驱动元件恢复功率。

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