专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US07598231B2 Tricyclic compound, compositions, and methods 有权
标题翻译：三环化合物，组合物和方法
公开(公告)号：US07598231B2
公开(公告)日：2009-10-06
申请号：US12023362
申请日：2008-01-31
申请人： Hengmiao (Henry) Cheng , Rajesh Devraj , Gary A DeCresenzo , Xiao Hu , Kevin D. Jerome , Mark Obukowicz , Lisa Olson , Paul V. Rucker , Ronald Keith Webber
发明人： Hengmiao (Henry) Cheng , Rajesh Devraj , Gary A DeCresenzo , Xiao Hu , Kevin D. Jerome , Mark Obukowicz , Lisa Olson , Paul V. Rucker , Ronald Keith Webber
IPC分类号： A61K31/675 , C07F9/58
CPC分类号： C07D213/89 , A61K31/44 , C07D213/72 , C07F9/58 , Y10S514/886
摘要： The present invention is directed to compounds of Formula I: or salt thereof, which are modulators of the glucocorticoid receptor. The compounds and salts of the invention are useful in the treatment of conditions mediated by glucocorticoid receptor activity.
摘要翻译：本发明涉及式I化合物或其盐，它们是糖皮质激素受体的调节剂。本发明的化合物和盐可用于治疗由糖皮质激素受体活性介导的病症。

2. 发明授权

US07786097B2 Tricyclic compounds, compositions and methods 有权
标题翻译：三环化合物，组合物和方法
公开(公告)号：US07786097B2
公开(公告)日：2010-08-31
申请号：US12506825
申请日：2009-07-21
申请人： Hengmiao (Henry) Cheng , Rajesh Devraj , Gary A Decresenzo , Xiao Hu , Kevin D. Jerome , Mark Obukowicz , Lisa Olson , Paul V. Rucker , Ronald Keith Webber
发明人： Hengmiao (Henry) Cheng , Rajesh Devraj , Gary A Decresenzo , Xiao Hu , Kevin D. Jerome , Mark Obukowicz , Lisa Olson , Paul V. Rucker , Ronald Keith Webber
IPC分类号： A61K31/675 , A61K31/44
CPC分类号： C07D213/89 , A61K31/44 , C07D213/72 , C07F9/58 , Y10S514/886
摘要： The present invention is directed to compounds of Formula I: or salt thereof, which are modulators of the glucocorticoid receptor. The compounds and salts of the invention are useful in the treatment of conditions mediated by glucocorticoid receptor activity.
摘要翻译：本发明涉及式I化合物或其盐，它们是糖皮质激素受体的调节剂。本发明的化合物和盐可用于治疗由糖皮质激素受体活性介导的病症。

3. 发明申请

US20080188443A1 Tricyclic Compound, Compositions, and Methods 有权
标题翻译：三环化合物，组合物和方法
公开(公告)号：US20080188443A1
公开(公告)日：2008-08-07
申请号：US12023362
申请日：2008-01-31
申请人： Hengmiao (Henry) Cheng , Rajesh Devraj , Gary A. DeCresenzo , Xiao Hu , Kevin D. Jerome , Mark Obukowicz , Lisa Olson , Paul V. Rucker , Ronald Keith Webber
发明人： Hengmiao (Henry) Cheng , Rajesh Devraj , Gary A. DeCresenzo , Xiao Hu , Kevin D. Jerome , Mark Obukowicz , Lisa Olson , Paul V. Rucker , Ronald Keith Webber
IPC分类号： A61K31/675 , C07D213/72 , A61K31/44 , A61P1/00 , A61P17/00 , A61P25/00 , A61P25/28 , A61P29/00 , A61P11/06 , C07K14/72 , C07F9/09
CPC分类号： C07D213/89 , A61K31/44 , C07D213/72 , C07F9/58 , Y10S514/886
摘要： The present invention is directed to compounds of Formula I: or salt thereof, which are modulators of the glucocorticoid receptor. The compounds and salts of the invention are useful in the treatment of conditions mediated by glucocorticoid receptor activity.
摘要翻译：本发明涉及式I化合物或其盐，它们是糖皮质激素受体的调节剂。本发明的化合物和盐可用于治疗由糖皮质激素受体活性介导的病症。

4. 发明申请

US20090281148A1 TRICYCLIC COMPOUNDS, COMPOSITIONS AND METHODS 有权
标题翻译：三元化合物，组合物和方法
公开(公告)号：US20090281148A1
公开(公告)日：2009-11-12
申请号：US12506825
申请日：2009-07-21
申请人： Hengmiao (Henry) Cheng , Rajesh Devraj , Gary A. Decresenzo , Xiao Hu , Kevin D. Jerome , Mark Obukowicz , Lisa Olson , Ronald Keith Webber
发明人： Hengmiao (Henry) Cheng , Rajesh Devraj , Gary A. Decresenzo , Xiao Hu , Kevin D. Jerome , Mark Obukowicz , Lisa Olson , Ronald Keith Webber
IPC分类号： A61K31/44
CPC分类号： C07D213/89 , A61K31/44 , C07D213/72 , C07F9/58 , Y10S514/886
摘要： The present invention is directed to compounds of Formula I: or salt thereof, which are modulators of the glucocorticoid receptor. The compounds and salts of the invention are useful in the treatment of conditions mediated by glucocorticoid receptor activity.
摘要翻译：本发明涉及式I化合物或其盐，它们是糖皮质激素受体的调节剂。本发明的化合物和盐可用于治疗由糖皮质激素受体活性介导的病症。

5. 发明申请

US20100286214A1 TRICYCLIC COMPOUNDS, COMPOSITIONS AND METHODS 有权
标题翻译：三元化合物，组合物和方法
公开(公告)号：US20100286214A1
公开(公告)日：2010-11-11
申请号：US12437704
申请日：2009-05-08
申请人： Hengmiao (Henry) Cheng , Xiao Hu , Kevin D. Jerome , Mark Obukowicz , Lisa Olson , Paul V. Rucker , Ronald Keith Webber
发明人： Hengmiao (Henry) Cheng , Xiao Hu , Kevin D. Jerome , Mark Obukowicz , Lisa Olson , Paul V. Rucker , Ronald Keith Webber
IPC分类号： A61K31/44 , C07K1/113
CPC分类号： C07D213/89 , A61K31/44 , C07D213/72 , C07F9/58 , Y10S514/886
摘要： The present invention is directed to compounds of Formula I: or salt thereof, which are modulators of the glucocorticoid receptor. The compounds and salts of the invention are useful in the treatment of conditions mediated by glucocorticoid receptor activity.
摘要翻译：本发明涉及式I化合物或其盐，它们是糖皮质激素受体的调节剂。本发明的化合物和盐可用于治疗由糖皮质激素受体活性介导的病症。

6. 发明申请

US20080312294A1 Tricyclic Compounds, Compositions, and Methods 有权
标题翻译：三环化合物，组合物和方法
公开(公告)号：US20080312294A1
公开(公告)日：2008-12-18
申请号：US12023323
申请日：2008-01-31
申请人： Hengmiao (Henry) Cheng , Xiao Hu , Kevin D. Jerome , Mark Obukowicz , Lisa Olson , Paul V. Rucker , Ronald Keith Webber
发明人： Hengmiao (Henry) Cheng , Xiao Hu , Kevin D. Jerome , Mark Obukowicz , Lisa Olson , Paul V. Rucker , Ronald Keith Webber
IPC分类号： A61K31/44 , C07D213/72 , C07K14/705 , A61P29/00 , A61P25/28
CPC分类号： C07D213/89 , A61K31/44 , C07D213/72 , C07F9/58 , Y10S514/886
摘要： The present invention is directed to compounds of Formula I: or salt thereof, which are modulators of the glucocorticoid receptor. The compounds and salts of the invention are useful in the treatment of conditions mediated by glucocorticoid receptor activity.
摘要翻译：本发明涉及式I化合物或其盐，它们是糖皮质激素受体的调节剂。本发明的化合物和盐可用于治疗由糖皮质激素受体活性介导的病症。

7. 发明申请

US20120088802A9 TRICYCLIC COMPOUNDS, COMPOSITIONS AND METHODS 有权
标题翻译：三元化合物，组合物和方法
公开(公告)号：US20120088802A9
公开(公告)日：2012-04-12
申请号：US12437704
申请日：2009-05-08
申请人： Hengmiao (Henry) Cheng , Xiao Hu , Kevin D. Jerome , Mark Obukowicz , Lisa Olson , Paul V. Rucker , Ronald Keith Webber
发明人： Hengmiao (Henry) Cheng , Xiao Hu , Kevin D. Jerome , Mark Obukowicz , Lisa Olson , Paul V. Rucker , Ronald Keith Webber
IPC分类号： A61K31/44 , C07K1/113
CPC分类号： C07D213/89 , A61K31/44 , C07D213/72 , C07F9/58 , Y10S514/886
摘要： The present invention is directed to compounds of Formula I: or salt thereof, which are modulators of the glucocorticoid receptor. The compounds and salts of the invention are useful in the treatment of conditions mediated by glucocorticoid receptor activity.
摘要翻译：本发明涉及式I化合物或其盐，它们是糖皮质激素受体的调节剂。本发明的化合物和盐可用于治疗由糖皮质激素受体活性介导的病症。

8. 发明申请

US20050107350A1 Method for the treatment or prevention of bone disorders with a cyclooxygenase-2 inhibitor alone and in combination with a bone disorder treatment agent and compositions therewith 审中-公开
标题翻译：用环氧合酶-2抑制剂单独治疗或预防骨病的方法，并与骨病症治疗剂及其组合物组合
公开(公告)号：US20050107350A1
公开(公告)日：2005-05-19
申请号：US10917104
申请日：2004-08-12
申请人： Lisa Olson
发明人： Lisa Olson
IPC分类号： A61K20060101 , A61K31/192 , A61K31/34 , A61K31/365 , A61K31/405 , A61K31/415 , A61K31/60
CPC分类号： A61K31/34 , A61K45/06 , A61K2300/00
摘要： The present invention describes a novel method for preventing or treating bone disorders and bone disorder-related complications in a subject involving a monotherapy with a Cox-2 inhibitor or a combination therapy with a Cox-2 inhibitor and a bone disorder treatment agent. Also described are therapeutic compositions comprising a Cox-2 inhibitor and a bone disorder treatment agent. Pharmaceutical compositions and kits for implementing the present method are also described.
摘要翻译：本发明描述了一种预防或治疗涉及使用Cox-2抑制剂或与Cox-2抑制剂和骨病症治疗剂的组合疗法的单一疗法的受试者的骨病和骨病症相关并发症的新方法。还描述了包含Cox-2抑制剂和骨病症治疗剂的治疗组合物。还描述了用于实现本方法的药物组合物和试剂盒。

9. 发明授权

US06729067B2 Outdoor refillable bait station 有权
标题翻译：户外充装诱饵站
公开(公告)号：US06729067B2
公开(公告)日：2004-05-04
申请号：US10230601
申请日：2002-08-29
申请人： James L. Lund , Gordon Morrison , Lisa Olson
发明人： James L. Lund , Gordon Morrison , Lisa Olson
IPC分类号： A01M2500
CPC分类号： A01M1/2011 , A01M1/026 , A01M31/002 , A01M2200/011
摘要： A device for baiting insects which includes an anchor tube that is placed in the ground, a base plate that attaches to the anchor tube, a cover that attaches to the base plate, a bait cup placed in said anchor tube and that sits beneath the ground, and a termite media support rod that attaches to the bait cup and sits in the anchor tube, beneath the ground, the key to open the cover and access the bait, the anchor tube being molded into one integrated piece with a continuous spiral fin or threaded member that acts as a screw mechanism when inserting the station into the ground and the base plate, which sits at ground level, includes insect entry openings; a cover covers the base plate and bait cup, protecting the bait from the elements; and optionally a termite media support rod, which includes a disk molded on the bottom thereof used to hold material for termite monitoring.
摘要翻译：一种用于诱饵昆虫的装置，其包括放置在地面中的锚管，附接到锚管的基板，附接到基板的盖，放置在所述锚管中并位于地面下方的诱饵杯，以及白蚁介质支撑杆，其连接到诱饵杯并且位于锚固管中，在地下，打开盖并进入诱饵的钥匙，锚管被模制成具有连续螺旋翅片的一个集成件，或螺纹构件在将工作站插入地面时用作螺钉机构，并且位于地面的基板包括昆虫入口; 盖子覆盖基板和诱饵杯，保护诱饵免受元素的伤害; 以及任选的白蚁介质支撑杆，其包括用于保持用于白蚁监测的材料的在其底部上模制的盘。

10. 发明授权

US06474015B1 Outdoor refillable bait station 有权
标题翻译：户外充装诱饵站
公开(公告)号：US06474015B1
公开(公告)日：2002-11-05
申请号：US09626702
申请日：2000-07-27
申请人： James L. Lund , Gordon Morrison , Lisa Olson
发明人： James L. Lund , Gordon Morrison , Lisa Olson
IPC分类号： A01M120
CPC分类号： A01M1/2011 , A01M1/026 , A01M31/002 , A01M2200/011
摘要： A device for baiting insects which includes an anchor tube that is placed in the ground, a base plate that attaches to the anchor tube, a cover that attaches to the base plate, a bait cup placed in said anchor tube and that sits beneath the ground, and a termite media support rod that attaches to the bait cup and sits in the anchor tube, beneath the ground, the key to open the cover and access the bait, the anchor tube being molded into one integrated piece with a continuous spiral fin or threaded member that acts as a screw mechanism when inserting the station into the ground and the base plate, which sits at ground level, includes insect entry openings; a cover covers the base plate and bait cup, protecting the bait from the elements; and optionally a termite media support rod, which includes a disk molded on the bottom thereof used to hold material for termite monitoring.
摘要翻译：一种用于诱饵昆虫的装置，其包括放置在地面中的锚管，附接到锚管的基板，附接到基板的盖，放置在所述锚管中并位于地面下方的诱饵杯，以及白蚁介质支撑杆，其连接到诱饵杯并且位于锚固管中，在地下，打开盖并进入诱饵的钥匙，锚管被模制成具有连续螺旋翅片的一个集成件，或螺纹构件在将工作站插入地面时用作螺钉机构，并且位于地面的基板包括昆虫入口; 盖子覆盖基板和诱饵杯，保护诱饵免受元素的伤害; 以及任选的白蚁介质支撑杆，其包括用于保持用于白蚁监测的材料的在其底部上模制的盘。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式