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1. 发明申请

US20140004560A1 RHIZOPUS ORYZAE STRAIN, MUTAGENESIS AND SCREENING METHODS THEREOF, AND METHODS OF FERMENTING TO PRODUCE FUMARIC ACID 有权
标题翻译：红霉素ORYZAE菌株，MUTAGENESIS和筛选方法及其生产方法
公开(公告)号：US20140004560A1
公开(公告)日：2014-01-02
申请号：US13992233
申请日：2011-04-16
申请人： He Huang , Shuang Li , Qing Xu , Zhen Gao
发明人： He Huang , Shuang Li , Qing Xu , Zhen Gao
IPC分类号： C12P7/46
CPC分类号： C12P7/46 , C12N1/14 , C12N15/01 , C12R1/845
摘要： A rhizopus oryzae strain, mutagenesis and screening methods thereof, and methods of producing fumaric acid by fermentation. The strain is named as Rhizopus oryzae ME-F13, and deposited in China Center for Type Culture Collection with depository number CCTCC M 2010351. The strain is obtained by physically mutagenizing the original strain ME-F12 through ion injection, culturing the processed bacteria on the solid selective plate containing 2-D-deoxylucose (2-DG) and picking up 2-DG-resistant single colony. The strain is capable of simultaneously saccharifying starchy material and fermenting it to produce fumaric acid. With an improved enzymatic activity, the strain can be directly used to ferment raw starchy materials without needing pre-saccharifying.
摘要翻译：根霉菌株，其诱变和筛选方法，以及通过发酵产生富马酸的方法。该菌株被命名为米曲霉ME-F13，并存放于中国型号培养基中心，存放号码为CCTCC M 2010351.该菌株是通过离子注射物理诱变原始菌株ME-F12获得的，含有2-D脱氧葡萄糖（2-DG）的固体选择性板和拾取2-DG抗性单个菌落。该菌株能够同时糖化淀粉物质并将其发酵以产生富马酸。具有改善的酶活性，该菌株可以直接用于发酵生淀粉材料，而不需要预糖化。

2. 发明授权

US08663972B2 Rhizopus oryzae strain, mutagenesis and screening methods thereof, and methods of fermenting to produce fumaric acid 有权
标题翻译：米根霉菌株，其诱变和筛选方法以及发酵产生富马酸的方法
公开(公告)号：US08663972B2
公开(公告)日：2014-03-04
申请号：US13992233
申请日：2011-04-16
申请人： He Huang , Shuang Li , Qing Xu , Zhen Gao
发明人： He Huang , Shuang Li , Qing Xu , Zhen Gao
IPC分类号： C12N1/14 , C12N15/01 , C12P7/46 , C12P19/20
CPC分类号： C12P7/46 , C12N1/14 , C12N15/01 , C12R1/845
摘要： A rhizopus oryzae strain, mutagenesis and screening methods thereof, and methods of producing fumaric acid by fermentation. The strain is named as Rhizopus oryzae ME-F13, and deposited in China Center for Type Culture Collection with depository number CCTCC M 2010351. The strain is obtained by physically mutagenizing the original strain ME-F12 through ion injection, culturing the processed bacteria on the solid selective plate containing 2-D-deoxylucose (2-DG) and picking up 2-DG-resistant single colony. The strain is capable of simultaneously saccharifying starchy material and fermenting it to produce fumaric acid. With an improved enzymatic activity, the strain can be directly used to ferment raw starchy materials without needing pre-saccharifying.
摘要翻译：根霉菌株，其诱变和筛选方法，以及通过发酵产生富马酸的方法。该菌株被命名为米曲霉ME-F13，并存放于中国型号培养基中心，存放号码为CCTCC M 2010351.该菌株是通过离子注射物理诱变原始菌株ME-F12获得的，含有2-D脱氧葡萄糖（2-DG）的固体选择性板和拾取2-DG抗性单个菌落。该菌株能够同时糖化淀粉物质并发酵以产生富马酸。具有改善的酶活性，该菌株可以直接用于发酵生淀粉材料，而不需要预糖化。

3. 发明申请

US20120258117A1 Methods and compositions for modulation of histone ubiquitination 审中-公开
标题翻译：用于调节组蛋白泛素化的方法和组合物
公开(公告)号：US20120258117A1
公开(公告)日：2012-10-11
申请号：US13440510
申请日：2012-04-05
申请人： C. W. Xu , Zhen Gao
发明人： C. W. Xu , Zhen Gao
IPC分类号： A61K39/395 , A61P35/00 , A61K31/7088 , C07H21/02 , A61K31/05 , C07K16/40 , C07C39/21 , C07H21/04 , C12N5/09 , A61K31/713
CPC分类号： A61K31/05 , A61K31/7088 , A61K31/713
摘要： Provided are methods and compositions for inhibiting mono-ubiquitination of a histone in a cell. Also provided are methods and compositions for inducing senescence in a cell. Additionally provided are methods and compositions for treatment of cancer, including glioma. In particular, these methods and compositions may include an inhibitor of a ubiquitin ligase.
摘要翻译：提供抑制细胞中组蛋白单泛素化的方法和组合物。还提供了用于在细胞中诱导衰老的方法和组合物。另外提供了用于治疗癌症的方法和组合物，包括神经胶质瘤。特别地，这些方法和组合物可以包括泛素连接酶的抑制剂。

4. 发明申请

US20150180626A1 DATA TRANSMISSION METHOD AND DEVICE 有权
标题翻译：数据传输方法和设备
公开(公告)号：US20150180626A1
公开(公告)日：2015-06-25
申请号：US14415619
申请日：2012-07-17
申请人： Peng Hao , Lining Yang , Can Huang , Zhen Gao
发明人： Peng Hao , Lining Yang , Can Huang , Zhen Gao
IPC分类号： H04L5/00
CPC分类号： H04L5/0044 , H04J3/047 , H04J3/1605
摘要： Provided is a data transmission method and device. The method includes: receiving IQ data from an uplink; according to the mapping of the IQ data in a Common Public Radio Interface (CPRI) basic frame, utilizing at least one storage unit to sequence the IQ data; combining a control word with the sequenced IQ data to form CPRI data, and transmitting the CPRI data. The solution utilizes at least one storage unit to sequence the IQ data, and extracts the sequenced data for a CPRI framing operation. This solution is simple in hardware processing and low in realization complexity. The change and upgrade of the transmission bandwidth of multiple modes (single mode or mixed mode) during system upgrade only occur on software layer without affecting the realization of hardware, thus having good flexibility.
摘要翻译：提供了一种数据传输方法和装置。该方法包括：从上行链路接收IQ数据; 根据公共无线电接口（CPRI）基本帧中的IQ数据的映射，利用至少一个存储单元对IQ数据进行排序; 将控制字与排序的IQ数据组合以形成CPRI数据，并发送CPRI数据。该解决方案利用至少一个存储单元对IQ数据进行排序，并提取CPRI成帧操作的排序数据。该解决方案在硬件处理上很简单，实现复杂度低。系统升级过程中多种模式（单模或混合模式）的传输带宽的变化和升级只发生在软件层，而不影响硬件的实现，具有良好的灵活性。

5. 发明授权

US09520971B2 Data transmission method and device 有权
标题翻译：数据传输方法及装置
公开(公告)号：US09520971B2
公开(公告)日：2016-12-13
申请号：US14415619
申请日：2012-07-17
申请人： Peng Hao , Lining Yang , Can Huang , Zhen Gao
发明人： Peng Hao , Lining Yang , Can Huang , Zhen Gao
IPC分类号： H04W4/00 , H04L5/00 , H04J3/04 , H04J3/16
CPC分类号： H04L5/0044 , H04J3/047 , H04J3/1605
摘要： Provided is a data transmission method and device. The method includes: receiving IQ data from an uplink; according to the mapping of the IQ data in a Common Public Radio Interface (CPRI) basic frame, utilizing at least one storage unit to sequence the IQ data; combining a control word with the sequenced IQ data to form CPRI data, and transmitting the CPRI data. The solution utilizes at least one storage unit to sequence the IQ data, and extracts the sequenced data for a CPRI framing operation. This solution is simple in hardware processing and low in realization complexity. The change and upgrade of the transmission bandwidth of multiple modes (single mode or mixed mode) during system upgrade only occur on software layer without affecting the realization of hardware, thus having good flexibility.
摘要翻译：提供了一种数据传输方法和装置。该方法包括：从上行链路接收IQ数据; 根据公共无线电接口（CPRI）基本帧中的IQ数据的映射，利用至少一个存储单元对IQ数据进行排序; 将控制字与排序的IQ数据组合以形成CPRI数据，并发送CPRI数据。该解决方案利用至少一个存储单元对IQ数据进行排序，并提取CPRI成帧操作的排序数据。该解决方案在硬件处理上很简单，实现复杂度低。系统升级过程中多种模式（单模或混合模式）的传输带宽的变化和升级只发生在软件层，而不影响硬件的实现，具有良好的灵活性。

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