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1. 发明申请

US20060263293A1 Click chemistry method for synthesizing molecular imaging probes 审中-公开
标题翻译：点击合成分子成像探针的化学方法
公开(公告)号：US20060263293A1
公开(公告)日：2006-11-23
申请号：US11413596
申请日：2006-04-27
申请人： Hartmuth Kolb , Joseph Walsh , Kai Chen
发明人： Hartmuth Kolb , Joseph Walsh , Kai Chen
IPC分类号： A61K51/00 , C07F5/00
CPC分类号： G01N33/534 , A61K51/0491 , C07D249/04 , C07H7/06 , C07H19/048 , C07H19/056 , C07H19/06
摘要： The present disclosure provides a method for preparing a radioactive ligand or radioactive substrate having affinity for a target biomacromolecule, the method comprising: (a) reacting a first compound comprising a first functional group capable of participating in a click chemistry reaction, with a radioactive reagent under conditions sufficient to displace the leaving group with a radioactive component of the radioactive reagent to form a first radioactive compound; (b) providing a second compound comprising a second complementary functional group capable of participating in a click chemistry reaction with the first functional group; (c) reacting the first functional group of the first radioactive compound with the complementary functional group of the second compound via a click chemistry reaction to form the radioactive ligand or substrate; and (d) isolating the radioactive ligand or substrate.
摘要翻译：本公开提供了制备对目标生物大分子具有亲和力的放射性配体或放射性底物的方法，所述方法包括：（a）使包含能够参与点击化学反应的第一官能团的第一化合物与放射性试剂在足以用放射性试剂的放射性成分置换离去基团以形成第一种放射性化合物的条件下，（b）提供包含能够与第一官能团参与点击化学反应的第二互补官能团的第二化合物; （c）通过点击化学反应使第一放射性化合物的第一官能团与第二化合物的互补官能团反应以形成放射性配体或底物; 和（d）分离放射性配体或底物。

2. 发明授权

US11275623B1 Core targeting in heterogeneous multiprocessor systems 有权
公开(公告)号：US11275623B1
公开(公告)日：2022-03-15
申请号：US16427285
申请日：2019-05-30
申请人： Michael Cieslak , Jiayao Yu , Kai Chen , Farnaz Azmoodeh , Michael David Marr , Jun Huang , Zahra Ferdowsi
发明人： Michael Cieslak , Jiayao Yu , Kai Chen , Farnaz Azmoodeh , Michael David Marr , Jun Huang , Zahra Ferdowsi
IPC分类号： G06F9/50 , G06F11/34 , G06F11/30
摘要： Systems, devices, media, and methods are presented for throttling (i.e., adjusting) the workload of an application (e.g., number of task requests) in order to improve processor core usage within a heterogeneous multiprocessor system. When high-performance processing is beneficial to the application, the number of task requests may be increased in order to have high-performance processor cores within the heterogeneous multiprocessor system core processor perform the tasks. On the other hand, when high-performance processing is not beneficial, the number of task requests may be decreased in order to have low-performance processor cores within the heterogeneous multiprocessor system perform the tasks. Processor core usage is monitored, and the number of tasks being performed are adjusted to match the processor core usage to a target processor core usage for functions the application is performing.

3. 发明授权

US11228394B2 Polar coding techniques for blind detection of different payload sizes 有权
公开(公告)号：US11228394B2
公开(公告)日：2022-01-18
申请号：US16765066
申请日：2018-09-24
申请人： Kai Chen , Changlong Xu , Jing Jiang , Gabi Sarkis , Hao Xu , Qualcomm Incorporated
发明人： Kai Chen , Changlong Xu , Jing Jiang , Gabi Sarkis , Hao Xu
IPC分类号： H04L1/00 , H03M13/45
摘要： Methods, systems, and devices for wireless communications are described. In some systems, wireless devices may encode and decode transmissions using polar codes. A transmitting device may encode a payload based on a selected payload size. For example, the transmitting device may construct a bit vector including payload bits, parity bits, frozen bits, or some combination of these, and may modify the bits or the order of the bits based on the selected payload size. The device may generate a polar-encoded codeword based on this bit vector, and may transmit the polar-encoded codeword to a receiving device. The receiving device may blind decode the polar-encoded codeword, and may determine the correct payload size based on the decoded bit vector. For example, the device may perform decoding or may check decoded bits based on a payload size hypothesis, where the decoding may fail for any incorrect payload size hypothesis.

4. 发明授权

US11146296B2 Codeword bit selection for rate-compatible polar coding 有权
公开(公告)号：US11146296B2
公开(公告)日：2021-10-12
申请号：US15733711
申请日：2019-04-02
申请人： QUALCOMM Incorporated , Kai Chen , Changlong Xu , Liangming Wu , Jing Jiang , Hao Xu
发明人： Kai Chen , Changlong Xu , Liangming Wu , Jing Jiang , Hao Xu
IPC分类号： H03M13/45 , H03M13/00 , H03M13/13 , H03M13/43 , H04L1/18
摘要： Various aspects of the present disclosure generally relate to wireless communication. In some aspects, an encoding device may determine a least reliable subset of information bits included in a set of information bits that includes a predefined active set of information bits to be encoded; may determine a codeword bit to be added to a codeword based at least in part on the least reliable subset of information bits, wherein adding the codeword bit to the codeword improves reliability of the least reliable subset of information bits; may add the codeword bit to the codeword; and may transmit the codeword. Numerous other aspects are provided.

5. 发明授权

US09727892B1 Determining related search terms for a domain 有权
公开(公告)号：US09727892B1
公开(公告)日：2017-08-08
申请号：US13284417
申请日：2011-10-28
申请人： Kai Chen , William David Reardon , Jinjun Xu
发明人： Kai Chen , William David Reardon , Jinjun Xu
IPC分类号： G06Q30/02
CPC分类号： G06Q30/0256
摘要： A method, system, and program product, for determining related search terms for a domain, comprising: receiving a request for related search terms for a domain, obtaining click data on the domain for initial related search terms determined for the domain, obtaining revenue generation data for each of a plurality of the initial related search terms; determining a first set of the initial related search terms with a highest revenue or ad clicks generation; generating a second set of new related search terms, comprising: obtaining keywords that are semantically relevant, obtaining how many advertisements are targeted to the respective keyword, and obtaining for each of multiple of the respective keywords an amount that advertisers have paid over a period of time for use of the respective keyword.

6. 发明授权

US09404957B2 Fault diagnosis and preliminary location system and method for transformer core looseness 有权
标题翻译：变压器铁芯松动故障诊断及初步定位系统及方法
公开(公告)号：US09404957B2
公开(公告)日：2016-08-02
申请号：US14128603
申请日：2012-07-19
申请人： Kai Chen , Chunning Wang , Hongzhong Ma , Kai Li , Yiming Wu , Ying Zhang , Hongtao Liu , Peng Gao , Taotao Chen
发明人： Kai Chen , Chunning Wang , Hongzhong Ma , Kai Li , Yiming Wu , Ying Zhang , Hongtao Liu , Peng Gao , Taotao Chen
IPC分类号： G01R31/02 , G01H1/00
CPC分类号： G01R31/027 , G01H1/00
摘要： This invention publishes a fault diagnosis and location system for transformer core looseness, consists of vibration sensors, data collection and computer. It is of power transformer fault intelligent diagnosis technology technical field. Fault diagnosis and location method uses three vibration sensors positioned on the top of transformer tank, to obtain vibration signal, uses signal processing to analyze the signal, and obtains fault characteristics of the transformer core looseness. The characteristics respectively are 50 Hz, 150 Hz and 300 Hz frequency components, in which 300 Hz is main feature. When they reach a certain value at one position, it suggests that transformer core looseness near this position. By the comparison of differences among signals of three positions, fault location can be done. This invention manifests fault characteristics accurately and detects core looseness efficiently.The invention uses the electricity grid frequency of 50 Hz for example, for 60 Hz power system, above 50 Hz, 150 Hz, 300 Hz characteristic frequencies are 60 Hz, 180 Hz and 360 Hz.
摘要翻译：本发明公布了变压器磁芯松动故障诊断定位系统，由振动传感器，数据采集和计算机组成。是电力变压器故障智能诊断技术技术领域。故障诊断和定位方法采用位于变压器箱顶部的三个振动传感器，获得振动信号，采用信号处理分析信号，获得变压器磁芯松动的故障特征。特性分别为50Hz，150Hz和300Hz频率分量，其中300Hz为主要特征。当它们在一个位置达到一定值时，表明变压器芯在这个位置附近松动。通过比较三个位置的信号之间的差异，可以进行故障定位。本发明精确表现了故障特征，有效地检测了磁芯的松动。本发明使用例如50Hz的电网频率，对于60Hz电力系统，高于50Hz，150Hz，300Hz特征频率为60Hz，180Hz和360Hz。

7. 发明授权

US09256981B2 Method and device for processing geological information 有权
标题翻译：地质信息处理方法及装置
公开(公告)号：US09256981B2
公开(公告)日：2016-02-09
申请号：US14117405
申请日：2012-01-20
申请人： Bin Shu , Chao Yang , Kai Zhang , Youjun Wang , Yong Wang , Zhishan Ren , Xinwei Luo , Congyun Li , Kai Chen , Chunhua Jiang , Guoyong Li , Jinglei Zhou , Tong Zhou , Xiaopeng Han
发明人： Bin Shu , Chao Yang , Kai Zhang , Youjun Wang , Yong Wang , Zhishan Ren , Xinwei Luo , Congyun Li , Kai Chen , Chunhua Jiang , Guoyong Li , Jinglei Zhou , Tong Zhou , Xiaopeng Han
IPC分类号： G06T7/00 , G06T17/05 , G06T3/40
CPC分类号： G06T17/05 , G06T3/4038 , G06T7/33 , G06T2207/10032 , G06T2207/30184
摘要： A method and a device for processing geological information is disclosed. The method for processing the geological information includes acquiring multiple geological image graphs, determining the relation between the image coordinate and the ground coordinate of each of the multiple geological image graphs by an imaging mode of geological images, and joining the multiple geological image graphs together according to the relation between the image coordinate and the ground coordinate of each of the multiple geological image graphs. Accordingly, large-scale ground images can be acquired by processing the geological images.
摘要翻译：公开了一种用于处理地质信息的方法和装置。用于处理地质信息的方法包括获取多个地质图像，通过地质图像的成像模式确定多个地质图像中的每一个的图像坐标与地面坐标之间的关系，并且将多个地质图像图按照对于多个地质图像中的每一个的图像坐标和地面坐标之间的关系。因此，可以通过处理地质图像来获取大规模地面图像。

8. 发明申请

US20150154655A1 SYSTEMS AND METHODS OF PROVIDING PARKED DOMAIN CONTENT 审中-公开
标题翻译：提供公园内容的系统和方法
公开(公告)号：US20150154655A1
公开(公告)日：2015-06-04
申请号：US13631472
申请日：2012-09-28
申请人： William David Reardon , Kai Chen
发明人： William David Reardon , Kai Chen
IPC分类号： G06Q30/02 , G06Q30/08
CPC分类号： G06Q30/0275
摘要： Systems and methods of providing content on a computer network are provided. A parked domain of the computer network is identified. The parked domain corresponds to an internet domain name associated with a web page. A data processing system can assign an assigned value to the web page. The assigned value can include an indication of revenue generated by a plurality of content items configured for display on the web page. A bid from a content provider to provide exclusive content for display on the web page can be received at the data processing system, and the data processing system can determine a bid value corresponding to the bid. The bid value can be compared with the assigned value to identify the bid as a winning bid, and the content placement circuit can provide the exclusive content corresponding to the winning bid for display on the web page.
摘要翻译：提供了在计算机网络上提供内容的系统和方法。识别计算机网络的驻留域。停放的域对应于与网页相关联的因特网域名。数据处理系统可以将分配的值分配给网页。分配值可以包括由被配置为在网页上显示的多个内容项产生的收入的指示。可以在数据处理系统处接收来自内容提供商的用于提供在网页上显示的独占内容的出价，并且数据处理系统可以确定与出价相对应的出价值。可以将出价值与指定值进行比较，以将出价确定为中标，并且内容放置电路可以提供与中标竞价对应的专属内容以在网页上显示。

9. 发明申请

US20130132603A1 Hybrid Networking System with Seamless Path Switching of Streams 有权
标题翻译：具有流的无缝路径切换的混合网络系统
公开(公告)号：US20130132603A1
公开(公告)日：2013-05-23
申请号：US13301562
申请日：2011-11-21
申请人： Etan Gur Cohen , Kai Chen
发明人： Etan Gur Cohen , Kai Chen
IPC分类号： G06F15/16
CPC分类号： H04L1/1841 , H04L45/125 , H04L45/22 , H04L45/24 , H04L47/6225 , H04L47/726 , H04L69/164
摘要： System and method for switching a stream to a new transmission medium. A first stream may be received. A first plurality of packets of the first stream may be transmitted to a second device on a first transmission medium. The first plurality of packets may include one or more index marker packets. It may be determined that at least a portion of the first plurality of packets may not have been received by the second device. A second plurality of packets of the first stream may be transmitted to the second device on a second transmission medium. The second plurality of packets may include at least a subset of the first plurality of packets and at least a subset of the one or more index marker packets. The one or more index marker packets may be configured for use by the second device to detect and discard duplicate packets.
摘要翻译：用于将流切换到新的传输介质的系统和方法。可以接收第一流。第一流的第一多个分组可以被发送到第一传输介质上的第二设备。第一多个分组可以包括一个或多个索引标记分组。可以确定第一多个分组的至少一部分可能没有被第二设备接收。第一流的第二多个分组可以在第二传输介质上被发送到第二设备。第二多个分组可以包括第一多个分组的至少一个子集以及一个或多个索引标记分组的至少一个子集。一个或多个索引标记分组可以被配置为由第二设备用于检测和丢弃重复分组。

10. 发明授权

US08420052B2 Imaging agents useful for identifying AD pathology 有权
标题翻译：用于识别AD病理学的成像剂
公开(公告)号：US08420052B2
公开(公告)日：2013-04-16
申请号：US12509259
申请日：2009-07-24
申请人： Hartmuth C. Kolb , Joseph C. Walsh , Wei Zhang , Umesh B. Gangadharmath , Dhanalakshmi Kasi , Kai Chen , Anjana Sinha , Eric Wang , Gang Chen , Peter J. H. Scott , Henry Clifton Padgett , Qianwa Liang , Zhiyong Gao , Tieming Zhao , Chunfang Xia , Vani P. Mocharla
发明人： Hartmuth C. Kolb , Joseph C. Walsh , Wei Zhang , Umesh B. Gangadharmath , Dhanalakshmi Kasi , Kai Chen , Anjana Sinha , Eric Wang , Gang Chen , Peter J. H. Scott , Henry Clifton Padgett , Qianwa Liang , Zhiyong Gao , Tieming Zhao , Chunfang Xia , Vani P. Mocharla
IPC分类号： A61K51/00 , A61M36/14
CPC分类号： C07D417/14 , A61K51/0406 , A61K51/0453 , A61K51/0455 , A61K51/0459 , C07D277/64 , C07D277/68 , C07D417/04 , C07D471/04 , C07D498/14 , C07D513/04 , C07D513/14
摘要： Provided herein are compounds and compositions which comprise the formulae as disclosed herein, wherein the compound is an amyloid binding compound. An amyloid binding compound according to the invention may be administered to a patient in amounts suitable for in vivo imaging of amyloid deposits, and distinguish between neurological tissue with amyloid deposits and normal neurological tissue. Amyloid probes of the invention may be used to detect and quantitate amyloid deposits in diseases including, for example, Down's syndrome, familial Alzheimer's Disease. In another embodiment, the compounds may be used in the treatment or prophylaxis of neurodegenerative disorders. Also provided herein are methods of allowing the compound to distribute into the brain tissue, and imaging the brain tissue, wherein an increase in binding of the compound to the brain tissue compared to a normal control level of binding indicates that the mammal is suffering from or is at risk of developing a neurodegenerative disease.
摘要翻译：本文提供了包含本文公开的式的化合物和组合物，其中所述化合物是淀粉样蛋白结合化合物。根据本发明的淀粉样蛋白结合化合物可以以适于淀粉样蛋白沉积物的体内成像的量施用于患者，并且可以区分具有淀粉样沉积物的神经组织和正常神经组织。本发明的淀粉样蛋白探针可用于检测和定量疾病中的淀粉样蛋白沉积物，包括例如唐氏综合症，家族性阿尔茨海默氏病。在另一个实施方案中，所述化合物可用于治疗或预防神经变性疾病。本文还提供了允许化合物分布到脑组织中并对脑组织成像的方法，其中与正常对照结合水平相比，化合物与脑组织的结合增加指示哺乳动物患有或有发展神经变性疾病的风险。

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