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1. 发明授权

US06416471B1 Portable remote patient telemonitoring system 失效
标题翻译：便携式远程病人远程监控系统
公开(公告)号：US06416471B1
公开(公告)日：2002-07-09
申请号：US09292405
申请日：1999-04-15
申请人： Harpal S. Kumar , Paul Johnson , Michael D. Llewellyn , William J. Mullarkey , William New, Jr. , Laurence J. Nicolson , William G. O'Brien , John D. Place , Peter M. Relph
发明人： Harpal S. Kumar , Paul Johnson , Michael D. Llewellyn , William J. Mullarkey , William New, Jr. , Laurence J. Nicolson , William G. O'Brien , John D. Place , Peter M. Relph
IPC分类号： A61B500
CPC分类号： G06F19/3418 , A61B5/0006 , A61B5/0022 , A61B5/7232 , A61B2560/0209 , G06F19/00 , G16H10/65 , Y02A90/22 , Y02A90/26 , Y10S128/903 , Y10S128/904
摘要： A system and method for monitoring vital signs and capturing data from a patient remotely using radiotelemetry techniques. The system is characterized by a cordless, disposable sensor band with sensors form measuring full waveform ECG, full waveform respiration, skin temperature, and motion, and transmission circuitry for the detection and transmission of vital signs data of the patient. A small signal transfer unit that can either be worn by the patient, e.g., on his or her belt, or positioned nearby receives data from the sensor band, which it then forwards by e.g., radio transmission to a base station that can be located up to 60 meters away. The base station receives data transmissions from the signal transfer unit and is designed to connect to conventional phone lines for transferring the collected data to a remote monitoring station. The base station may also capture additional clinical data, such as blood pressure data, and to perform data checks. Patient safety is enhanced by the ability of the base station to compare clinical data, e.g., ECG, against given profiles and to mark events when appropriate or when the base station is programmed to do so. Such events are indicated to the physician and could be indicated to the patient by reverse transmission to the signal transfer unit. A remote monitoring station allows the presentation and review of data (including events) forwarded by the sensor band. ECG analysis software and a user-friendly graphical user interface are provided to remotely analyze the transmitted data and to permit system maintenance and upkeep. The system of the invention has useful application to the collection of patient clinical data during drug trials and medical testing for regulatory approvals as well as management of patients with chronic diseases.
摘要翻译：一种用于使用无线电测量技术远程监测生命体征并从患者捕获数据的系统和方法。该系统的特点是无绳，一次性传感器带，传感器形成测量全波形ECG，全波形呼吸，皮肤温度和运动，以及用于检测和传输患者生命体征数据的传输电路。可以由患者穿戴的小信号传递单元，例如在他或她的皮带上，或者位于附近，从传感器带接收数据，然后传感器带通过例如无线电传输转发到可以位于上的基站到60米远。基站从信号传送单元接收数据传输，并被设计成连接到传统的电话线路，用于将收集的数据传送到远程监控站。基站还可以捕获额外的临床数据，例如血压数据，并执行数据检查。通过基站比较临床数据（例如ECG）与给定配置文件的能力以及在适当时或当基站进行编程时标记事件的能力来增强患者安全性。向医生指示这种事件，并且可以通过向信号传送单元的反向传输向患者指示。远程监控站允许呈现和检查由传感器带转发的数据（包括事件）。提供ECG分析软件和用户友好的图形用户界面，以远程分析传输的数据并允许系统维护和维护。本发明的系统可用于在药物试验期间收集患者临床数据，并进行监管批准的医疗检测以及慢性病患者的管理。

2. 发明授权

US06450953B1 Portable signal transfer unit 失效
标题翻译：便携式信号传输单元
公开(公告)号：US06450953B1
公开(公告)日：2002-09-17
申请号：US09292158
申请日：1999-04-15
申请人： John D. Place , Paul Johnson , Steven Jones , Harpal S. Kumar , William J. Mullarkey , William New, Jr. , Laurence J. Nicolson , Peter M. Relph
发明人： John D. Place , Paul Johnson , Steven Jones , Harpal S. Kumar , William J. Mullarkey , William New, Jr. , Laurence J. Nicolson , Peter M. Relph
IPC分类号： A61B500
CPC分类号： A61B5/0002 , Y10S128/903
摘要： A portable signal transfer unit for relaying a signal representative of physiological data of a mammalian subject from a remote physiological sensor to a remote receiver unit. The portable transfer unit includes an input device which operably receives the signal, a memory for buffering the signal, and an output device which wirelessly transmits the signal to the remote unit. The signal transfer unit also includes a signal processor for relaying the signal from the signal input to the output device, wherein the signal processor has two or more receivers each receiver adapted to handle a specified signal carrier frequency. An indicator is also provided which indicates to the subject whether the signal transfer unit is within range of the remote unit to enable effective transmission of the signal from the signal transfer unit to the remote unit.
摘要翻译：一种便携式信号传送单元，用于将表示哺乳动物受试者的生理数据的信号从远程生理传感器传送到远程接收器单元。便携式传送单元包括可操作地接收信号的输入设备，用于缓冲信号的存储器以及将信号无线地发送到远程单元的输出设备。信号传送单元还包括用于将信号从信号输入中继到输出设备的信号处理器，其中信号处理器具有两个或多个接收器，每个接收器适于处理指定的信号载波频率。还提供了一个指示器，其向主体指示信号传送单元是否在远程单元的范围内，以使信号能够从信号传送单元有效传输到远程单元。

3. 发明授权

US06494829B1 Physiological sensor array 失效
标题翻译：生理传感器阵列
公开(公告)号：US06494829B1
公开(公告)日：2002-12-17
申请号：US09292159
申请日：1999-04-15
申请人： William New, Jr. , Andrea J. Harry , Paul Johnson , Harpal S. Kumar , William J. Mullarkey , Laurence J. Nicolson , John D. Place
发明人： William New, Jr. , Andrea J. Harry , Paul Johnson , Harpal S. Kumar , William J. Mullarkey , Laurence J. Nicolson , John D. Place
IPC分类号： A61B500
CPC分类号： H04M11/002 , A61B5/0002 , A61B5/0205 , A61B5/04085 , A61B5/1135 , G06F19/00 , Y10S128/903
摘要： A physiological sensor device for attachment to a mammalian subject comprising an output transmitter, at least two physiological sensors each for sensing one of the subject's physiological parameters, and a controller operably in communication with the physiological sensors which controller communicates a signal comprising data representative of both the sensed physiological parameters to the output transmitter which operably transmits the signal to a remote location, wherein the controller comprises a multiplexer which operably switches the data from both the physiological sensors into a serial output signal. Respiration may be detected by a bend sensor including an elongate member and an electrical component mounted thereon which electrical component has an electrical property which varies in dependence on the extent of bending of the elongate member. Other parameters such as temperature and full waveform ECG may also be measured.
摘要翻译：一种用于附接到哺乳动物受试者的生理传感器装置，包括输出发射器，每个用于感测受试者生理参数之一的至少两个生理传感器，以及可操作地与生理传感器通信的控制器，所述控制器传达包括代表两者的数据的信号感测到的输出发射器的生理参数，其可操作地将信号传输到远程位置，其中控制器包括将数据从生理传感器可操作地切换成串行输出信号的多路复用器。呼吸可以由包括细长构件和安装在其上的电气部件的弯曲传感器检测到，该电气部件具有根据细长构件的弯曲程度而变化的电性质。也可以测量其他参数，例如温度和全波形ECG。

4. 发明授权

US06385473B1 Physiological sensor device 失效
标题翻译：生理传感器装置
公开(公告)号：US06385473B1
公开(公告)日：2002-05-07
申请号：US09292157
申请日：1999-04-15
申请人： Paul D. Haines , Andrea J. Harry , Harpal S. Kumar , John D. Place , Susan B. Riley Earl , Neil J. Sheehan , David A. Sheraton
发明人： Paul D. Haines , Andrea J. Harry , Harpal S. Kumar , John D. Place , Susan B. Riley Earl , Neil J. Sheehan , David A. Sheraton
IPC分类号： A61B50478
CPC分类号： A61B5/0006 , A61B5/04085
摘要： A physiological sensor device for attachment to a mammalian subject including first and second regions of sensors attachable to a subject in use, which first and second regions of sensors are separated by a flexible web adapted to enable variable separation of the first and second sensor regions from one another in use. The physiological sensor device is manufactured by forming a strip of electrically conductive material on a flexible electrically non-conductive substrate and cutting a slot through both the flexible substrate and conductive strip to define a pair of adjacent edges of conductive material separated by a non-conductive gap thereby also to define adjacent electrode sensors each having one of the pair of adjacent edges formed in the strip of conductive material. The physiological sensor device is attached to the subject for measurement of numerous physiological parameters for a period of time, such as 24 hours, and is then thrown away.
摘要翻译：一种用于附接到哺乳动物对象的生理传感器装置，包括可附接到使用中的受试者的传感器的第一和第二区域，所述传感器的第一和第二区域被柔性腹板分隔开，柔性腹板适于使第一和第二传感器区域从另一个在使用。生理传感器装置通过在柔性非导电衬底上形成导电材料条并通过柔性衬底和导电条切割缝隙来限定一对相邻的导电材料边缘，由导电材料分隔开的非导电材料间隙，从而也限定相邻的电极传感器，每个相邻电极传感器各自具有形成在导电材料条中的一对相邻边缘中的一个。将生理传感器装置附着到被检体上用于测量许多生理参数一段时间，例如24小时，然后被丢弃。

5. 外观设计

USD425203S Chest multisensor array 失效
公开(公告)号：USD425203S
公开(公告)日：2000-05-16
申请号：US103527
申请日：1999-04-15
申请人： Neil J. Sheehan , Paul D. Haines , Harpal S. Kumar , John D. Place , Susan B. Riley Earl , David A. Sheraton
设计人： Neil J. Sheehan , Paul D. Haines , Harpal S. Kumar , John D. Place , Susan B. Riley Earl , David A. Sheraton

6. 发明授权

US06454708B1 Portable remote patient telemonitoring system using a memory card or smart card 失效
标题翻译：使用存储卡或智能卡的便携式远程病人远程监控系统
公开(公告)号：US06454708B1
公开(公告)日：2002-09-24
申请号：US09591597
申请日：2000-06-09
申请人： Pete Ferguson , Harpal Kumar , Graham Lay , Mike Llewellyn , John D. Place
发明人： Pete Ferguson , Harpal Kumar , Graham Lay , Mike Llewellyn , John D. Place
IPC分类号： A61B500
CPC分类号： A61B5/6831 , A61B5/0006 , A61B5/0022 , A61B5/02055 , A61B5/11 , A61B5/1455 , A61B5/7232 , A61B5/742 , A61B5/7435 , A61B2560/0209 , A61B2560/0412 , A61B2560/0475 , G06F19/00 , G06F19/3418 , G16H10/65 , Y02A90/26 , Y10S128/903 , Y10S128/904
摘要： A system and method for monitoring health parameters and capturing data from a subject. The system is characterized by a cordless, disposable sensor band with sensors for measuring full waveform ECG, full waveform respiration, skin temperature, and motion, and a connector which accepts a memory card or a smart card for storage of the measured data. After a predetermined period of time, such as when the sensor band is removed, the memory card or smart card is removed and inserted into a monitoring device which reads the stored health parameter data of the subject. The monitoring device includes a base station that includes a memory/smart card reader and is connected to conventional phone lines for transferring the collected data to a remote monitoring station. The base station may also capture additional clinical data, such as blood pressure data, and to perform data checks. Subject safety is enhanced by the ability of the base station to compare clinical data, e.g. ECG, against given profiles and to mark events when appropriate or when the base station is programmed to do so. The remote monitoring station allows the presentation and review of data (including events) forwarded by the sensor band. ECG analysis software and a user-friendly graphical user interface are provided to remotely analyze the transmitted data and to permit system maintenance and upkeep. In alternative embodiments, a smart card includes the sensor band's electronics and/or signal transmission circuitry in conjunction with a portable data logger so that the electronics may be reused from one disposable sensor band to the next without limiting the patient's range of movement. The system of the invention has useful application to the collection of subject clinical data during drug trials and medical testing for regulatory approvals as well as management of subjects with chronic diseases.
摘要翻译：用于监测健康参数并从受试者捕获数据的系统和方法。该系统的特征在于具有用于测量全波形ECG，全波形呼吸，皮肤温度和运动的传感器的无绳，一次性传感器带，以及接受用于存储测量数据的存储卡或智能卡的连接器。在预定时间段之后，例如当传感器带被移除时，存储卡或智能卡被移除并插入到监视装置中，该监视装置读取存储的对象的健康参数数据。监视装置包括基站，其包括存储器/智能卡读取器，并且连接到常规电话线，用于将收集的数据传送到远程监控站。基站还可以捕获额外的临床数据，例如血压数据，并执行数据检查。通过基站比较临床数据的能力来增强受试者的安全性，例如 ECG，针对给定的配置文件，并在适当时或当基站进行编程时标记事件。远程监控站允许呈现和检查由传感器带转发的数据（包括事件）。提供ECG分析软件和用户友好的图形用户界面，以远程分析传输的数据并允许系统维护和维护。在替代实施例中，智能卡包括结合便携式数据记录器的传感器带的电子和/或信号传输电路，使得电子设备可以从一个一次性传感器带重新使用到下一个，而不限制患者的移动范围。本发明的系统可用于在药物试验和医学检验期间收集受试临床数据以进行监管批准以及对慢性疾病受试者的管理。

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