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1. 发明授权

US08784421B2 Apparatus and methods for removing vertebral bone and disc tissue 有权
标题翻译：用于去除椎骨和椎间盘组织的装置和方法
公开(公告)号：US08784421B2
公开(公告)日：2014-07-22
申请号：US10793185
申请日：2004-03-03
申请人： Harold F. Carrison , Mukund R. Patel , Stanley W. Olson, Jr.
发明人： Harold F. Carrison , Mukund R. Patel , Stanley W. Olson, Jr.
IPC分类号： A61B17/56
CPC分类号： A61B17/1671 , A61B17/1604 , A61B17/1615 , A61B17/1617 , A61B17/1631 , A61B17/1633 , A61B17/1662 , A61B17/221 , A61B17/32002 , A61B17/320725 , A61B2017/00261 , A61B2017/003 , A61B2017/22038 , A61B2017/320028 , A61B2017/320032 , A61B2217/005 , A61B2217/007
摘要： Tissue removal probes comprise an elongated member, a drive shaft rotatably disposed within the member, and a rotatable tissue removal element mounted to the distal end of the drive shaft. One tissue removal element comprises a plurality of tissue-cutting filaments affixed at proximal and distal ends of the tissue removal element. The cutting filaments may have optional hinge points that allow the distal end of the tissue removal element to be inverted, thereby transforming the tissue removal element from a tissue-cutting device to a tissue-grasping device. Another tissue removal element may have a blunted tip to prevent distal tissue trauma and an irrigation port to provide irrigation fluid to the removed tissue and/or tissue removal element. Another tissue removal element has a proximal and distal spiral grooves that are oppositely pitched, so that removed tissue can be collected in the middle of the tissue removal element.
摘要翻译：组织移除探针包括细长构件，可旋转地设置在构件内的驱动轴和安装到驱动轴的远端的可旋转的组织去除元件。一个组织去除元件包括固定在组织去除元件的近端和远端的多个组织切割细丝。切割细丝可以具有允许组织去除元件的远端反转的任选的铰链点，从而将组织去除元件从组织切割装置转变成组织抓取装置。另一个组织去除元件可以具有钝的尖端以防止远端组织创伤和冲洗端口向被去除的组织和/或组织去除元件提供冲洗流体。另一组织去除元件具有相对地倾斜的近端和远端螺旋槽，使得去除的组织可以被收集在组织移除元件的中间。

2. 发明授权

US07252686B2 Methods for reducing bone compression fractures using wedges 有权
$Methods for reducing bone compression fractures using wedges$
标题翻译：减少使用楔形骨折的方法
公开(公告)号：US07252686B2
公开(公告)日：2007-08-07
申请号：US10639871
申请日：2003-08-13
申请人： Harold F. Carrison , Stanley W. Olson, Jr. , Lex P. Jansen
发明人： Harold F. Carrison , Stanley W. Olson, Jr. , Lex P. Jansen
IPC分类号： A61F2/44
CPC分类号： A61B17/3468 , A61B17/3472 , A61B17/8852 , A61B2017/00261
摘要： Devices, kits, and methods are provided for treating a bone structure, e.g., a vertebra, with a compression fracture. Wedges can be introduced into the bone structure in a direction that is lateral to the compression fracture, and stacked on tope of each to apply forces to the bone structure to reduce the compression fracture. The wedges can be introduced into the bone structure using a cannula. The wedges can be introduced as wedge pairs, in which case, a subsequent wedge pair can be introduced between a previously introduced wedge pair in order to drive the previously introduced wedges apart to create the stacking arrangement. Optionally, the wedges can be provided with longitudinal bores, in which case, they can be introduced into the bone structure, over a guide member that is threaded through the bores.
摘要翻译：提供了用压缩骨折治疗骨骼结构例如椎骨的装置，试剂盒和方法。楔子可以沿着压缩断裂侧面的方向被引入骨结构中，并且将其堆叠在每个的顶部以向骨结构施加力以减少压缩性骨折。可以使用插管将楔形物引入骨结构。楔形物可以作为楔形对引入，在这种情况下，可以在先前引入的楔形对之间引入随后的楔形对，以便将先前引入的楔形物分开以产生堆叠布置。可选地，楔形物可以设置有纵向孔，在这种情况下，它们可以在穿过孔的引导构件上引入到骨结构中。

3. 发明授权

US5980550A Water-soluble coating for bioactive vasoocclusive devices 失效
标题翻译：用于生物活性血管收缩装置的水溶性涂层
公开(公告)号：US5980550A
公开(公告)日：1999-11-09
申请号：US100426
申请日：1998-06-18
申请人： Joseph C. Eder , Stanley W. Olson, Jr. , Paul C. Slaikeu , Robert M Abrams
发明人： Joseph C. Eder , Stanley W. Olson, Jr. , Paul C. Slaikeu , Robert M Abrams
IPC分类号： A61B17/12 , A61M29/00
CPC分类号： A61B17/12022 , A61B17/12145 , A61B17/1215
摘要： A vaso-occlusive device having a bioactive inner coating and a water-soluble outer coating. Methods of preparing the devices are also provided.
摘要翻译：一种具有生物活性内涂层和水溶性外涂层的血管闭塞装置。还提供了制备装置的方法。

4. 发明授权

US06960215B2 Tactical detachable anatomic containment device and therapeutic treatment system 失效
标题翻译：战术可拆卸解剖装置和治疗系统
公开(公告)号：US06960215B2
公开(公告)日：2005-11-01
申请号：US10142133
申请日：2002-05-08
申请人： Stanley W. Olson, Jr. , Lex P. Jansen , Michael Burns
发明人： Stanley W. Olson, Jr. , Lex P. Jansen , Michael Burns
IPC分类号： A61B17/12 , A61B17/22 , A61B17/88 , A61B17/70 , A61F2/44
CPC分类号： A61B17/7097 , A61B17/12027 , A61B17/1204 , A61B17/12099 , A61B17/12136 , A61B17/12172 , A61B17/7098 , A61B2017/1205 , A61B2017/12063 , A61B2017/22051
摘要： Devices and methods for the controlled delivery of therapeutic agents into bone and soft tissue to prevent the unintentional migration of therapeutic agents from the treatment site. The containment device can be made of a fabric or membrane that is porous, semi-porous, non-porous, bio-resorbable, or non-resorbable materials. A containment device is advanced to the interior of the target structure and filled with a therapeutic agent. The containment device may be permanently or temporarily implanted. Where permanent implantation is desired, the containment device may be detached via a severable junction.
摘要翻译：用于将治疗剂控制递送到骨和软组织中以防止治疗剂从治疗部位意外迁移的装置和方法。容纳装置可以由多孔，半多孔，无孔，生物可吸收或不可再吸收材料的织物或膜制成。容纳装置前进到目标结构的内部并填充有治疗剂。容纳装置可以永久地或临时植入。在需要永久性植入的情况下，容纳装置可以通过可分离的连接部分离。

5. 发明授权

US07901407B2 Media delivery device for bone structures 有权
标题翻译：用于骨骼结构的介质输送装置
公开(公告)号：US07901407B2
公开(公告)日：2011-03-08
申请号：US10211492
申请日：2002-08-02
申请人： Stanley W. Olson, Jr. , Lex P. Jansen , Michael Burns
发明人： Stanley W. Olson, Jr. , Lex P. Jansen , Michael Burns
IPC分类号： A61F2/46
CPC分类号： A61B17/1617 , A61B17/1671 , A61B17/1757 , A61B17/885 , A61B2017/8838 , A61F2002/4602
摘要： Apparatus for delivering a media to an anatomic void within a bone structure and compacting the media within the anatomic void includes a delivery device and a compaction device. The delivery device includes a tubular element, a guidewire, and a removal element. The removal element is capable of forming a void at a target site within the bone structure by cutting and/or deforming target bone tissue. A distal end of the guidewire may be detachable as a safety feature. The compaction device includes an elongate member and a vibration device connected to the proximal end of the elongate member. The vibration device creates vibration at the distal end of the elongate member, so that the media is mixed and/or compacted within the anatomic void.
摘要翻译：用于将介质输送到骨结构内的解剖空隙并压实解剖空隙内的介质的装置包括输送装置和压实装置。输送装置包括管状元件，导丝和去除元件。移除元件能够通过切割和/或变形靶骨组织而在骨结构内的目标部位形成空隙。导线的远端可以作为安全特征而可拆卸。压实装置包括细长构件和连接到细长构件的近端的振动装置。振动装置在细长构件的远端处产生振动，使得介质在解剖空隙内混合和/或压实。

6. 发明授权

US06830561B2 Catheter with protective sleeve 失效
标题翻译：导管带保护套
公开(公告)号：US06830561B2
公开(公告)日：2004-12-14
申请号：US10142575
申请日：2002-05-08
申请人： Lex P. Jansen , Stanley W. Olson, Jr. , Robert M. Abrams
发明人： Lex P. Jansen , Stanley W. Olson, Jr. , Robert M. Abrams
IPC分类号： A61M532
CPC分类号： A61M25/0113 , A61M25/0119 , A61M25/0662 , A61M2025/0007 , A61M2025/0681
摘要： A device for accessing the spinal canal of a patient includes an introducer and a protective sleeve that is attached at one end thereof to a proximal end of the introducer. The protective sleeve has an outer stationary portion and an inner moveable portion. The outer and inner portions of the protective sleeve are separated by a crown region. A catheter is disposed inside the protective sleeve. During operation, the protective sleeve is advanced within the spinal canal to form a protective barrier between the catheter and the spinal cord. The catheter is advanced and retracted within the protective sleeve.
摘要翻译：用于接近患者的椎管的装置包括导引器和保护套筒，其在其一端附接到导引器的近端。保护套具有外固定部和内可动部。保护套的外部和内部由冠部区域分开。导管设置在保护套内。在操作期间，保护套在椎管内前进，以在导管和脊髓之间形成保护屏障。导管先进并在保护套内缩回。

7. 发明授权

US07591822B2 Retrograde plunger delivery system 有权
标题翻译：逆行柱塞输送系统
公开(公告)号：US07591822B2
公开(公告)日：2009-09-22
申请号：US10786251
申请日：2004-02-24
申请人： Stanley W. Olson, Jr. , Lex P. Jansen , Michael Burns
发明人： Stanley W. Olson, Jr. , Lex P. Jansen , Michael Burns
IPC分类号： A61B17/56
CPC分类号： A61B17/7098 , A61B17/8811 , A61M25/0069 , A61M25/007 , A61M2210/02
摘要： Cannulas are provided for delivering therapeutic material to a treatment site. The cannula includes a cannula body with a plurality of openings at the distal end, including a longitudinal opening and a plurality of transverse openings that are axially spaced from each other. The cannula also includes a plunger that is configured to be slidably disposed within the cannula lumen. When the plunger is proximally displaced in the cannula lumen, the plunger seals the distal end and deflects the therapeutic material out the transverse openings. As the plunger is proximally displaced within the lumen, the therapeutic material is forced to perfuse out transverse openings located proximal of the plunger position. In one embodiment, the plunger includes an additional pliable sealable member. In another embodiment, the distal end of the cannula body may be implanted by separating the distal end from the cannula body.
摘要翻译：提供插管用于将治疗材料递送至治疗部位。套管包括在远端具有多个开口的套管主体，包括纵向开口和彼此轴向间隔开的多个横向开口。插管还包括被构造成可滑动地设置在套管内腔内的柱塞。当柱塞在套管腔中向近端移位时，柱塞密封远端并使治疗材料偏离横向开口。当柱塞在腔内向近端移位时，治疗材料被迫灌注位于柱塞位置附近的横向开口。在一个实施例中，柱塞包括附加的柔韧的可密封构件。在另一个实施例中，套管本体的远端可以通过将远端与套管主体分离而被植入。

8. 发明授权

US06730095B2 Retrograde plunger delivery system 失效
标题翻译：逆行柱塞输送系统
公开(公告)号：US06730095B2
公开(公告)日：2004-05-04
申请号：US10183220
申请日：2002-06-26
申请人： Stanley W. Olson, Jr. , Lex P. Jansen , Michael Burns
发明人： Stanley W. Olson, Jr. , Lex P. Jansen , Michael Burns
IPC分类号： A61B1758
CPC分类号： A61B17/7098 , A61B17/8811 , A61M25/0069 , A61M25/007 , A61M2210/02
摘要： Cannulas are provided for delivering therapeutic material to a treatment site. The cannula includes a cannula body with a plurality of openings at the distal end, including a longitudinal opening and a plurality of transverse openings that are axially spaced from each other. The cannula also includes a plunger that is configured to be slidably disposed within the cannula lumen. When the plunger is proximally displaced in the cannula lumen, the plunger seals the distal end and deflects the therapeutic material out the transverse openings. As the plunger is proximally displaced within the lumen, the therapeutic material is forced to perfuse out transverse openings located proximal of the plunger position. In one embodiment, the plunger includes an additional pliable sealable member. In another embodiment, the distal end of the cannula body may be implanted by separating the distal end from the cannula body.
摘要翻译：提供插管用于将治疗材料递送至治疗部位。套管包括在远端具有多个开口的套管主体，包括纵向开口和彼此轴向间隔开的多个横向开口。插管还包括被构造成可滑动地设置在套管内腔内的柱塞。当柱塞在套管腔中向近端移位时，柱塞密封远端并使治疗材料偏离横向开口。当柱塞在腔内向近端移位时，治疗材料被迫灌注位于柱塞位置附近的横向开口。在一个实施例中，柱塞包括附加的柔韧的可密封构件。在另一个实施例中，套管本体的远端可以通过将远端与套管主体分离而被植入。

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