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1. 发明申请

US20100092338A1 Test element magazine 审中-公开
标题翻译：测试元素杂志
公开(公告)号：US20100092338A1
公开(公告)日：2010-04-15
申请号：US12622595
申请日：2009-11-20
申请人： Hans List , Hans-Peter Haar , George Bevan Kirby Meacham
发明人： Hans List , Hans-Peter Haar , George Bevan Kirby Meacham
IPC分类号： G01N33/50 , A61B5/151 , G01N33/48 , A61B5/157
CPC分类号： A61B5/15176 , A61B5/14532 , A61B5/1455 , A61B5/150022 , A61B5/150358 , A61B5/150419 , A61B5/150503 , A61B5/15113 , A61B5/15146 , A61B5/15151 , A61B5/15161 , A61B2562/242
摘要： A test element magazine for a system for measuring the concentration of at least one constituent in a fluid sample is provided. The test element magazine comprises at least one test element in at least one chamber. The chamber is individually sealed by a sealing element. The test element comprises at least one active portion for contacting a skin portion of a patient and/or for contacting a fluid sample, wherein the test element further comprises at least one support body, wherein the support body is adapted for being engaged by an actuator. By a forward movement of the test element the support body of the test element applies a force to the sealing element, thereby forcing open the sealing of the chamber.
摘要翻译：提供了一种用于测量流体样品中至少一种成分的浓度的系统的测试元件盒。测试元件盒包括至少一个室中的至少一个测试元件。室由密封元件单独密封。测试元件包括用于接触患者的皮肤部分和/或用于接触流体样本的至少一个活动部分，其中所述测试元件还包括至少一个支撑体，其中所述支撑体适于由致动器。通过测试元件的向前运动，测试元件的支撑体向密封元件施加力，从而强制打开腔室的密封。

2. 发明授权

US06986754B2 Needleless hypodermic injection system, application device and medication cartridge therefor 失效
公开(公告)号：US06986754B2
公开(公告)日：2006-01-17
申请号：US10101400
申请日：2002-03-19
申请人： Hans-Peter Haar , George Bevan Kirby Meacham , Konrad Joseph Popp , Otto Bruntrup , Ulrich Josef Riemensperger , Guenter Franz Ihle , Bruno Robert Thös , Hans List , Dirk Bandau , Horst Engelhardt , Christian Gliewe
发明人： Hans-Peter Haar , George Bevan Kirby Meacham , Konrad Joseph Popp , Otto Bruntrup , Ulrich Josef Riemensperger , Guenter Franz Ihle , Bruno Robert Thös , Hans List , Dirk Bandau , Horst Engelhardt , Christian Gliewe
IPC分类号： A61M5/30
CPC分类号： A61M5/30 , A61M5/2046 , A61M5/2425 , A61M5/3129 , A61M5/5086 , A61M2005/2013 , A61M2005/3118 , A61M2005/312 , A61M2205/582 , A61M2205/583
摘要： A needleless hypodermic injection system for injecting a liquid medication, which system comprises a disposable cartridge which contains a medication and which includes a propellant and an igniter, and a reusable application device which comprises a pressure chamber for receiving the medication cartridge, actuation means including an ignition system and means for ensuring reliability and safety of the system. The reusable application device comprises: (a) a housing including a fist housing section and a second housing section which are adapted to be assembled together by a screwing operation, the first housing section comprising a front part having an injection outlet and a chamber adapted to receive a the cartridge contains the medication to be injected and also contains a propellant and an igniter, and (b) means for selectively activating said igniter of said cartridge when predetermined conditions are fulfilled.

3. 发明授权

US07811236B2 Puncturing system for collecting body fluid sample 有权
标题翻译：用于收集体液样品的穿刺系统
公开(公告)号：US07811236B2
公开(公告)日：2010-10-12
申请号：US12122908
申请日：2008-05-19
申请人： Hans List , Hans-Peter Haar , George Bevan Kirby Meacham , Michael Eusemann
发明人： Hans List , Hans-Peter Haar , George Bevan Kirby Meacham , Michael Eusemann
IPC分类号： A61B5/00 , A61B5/15 , A61B5/157 , A61B17/32
CPC分类号： A61B5/15196 , A61B5/14514 , A61B5/150022 , A61B5/150152 , A61B5/150175 , A61B5/15019 , A61B5/150419 , A61B5/150519 , A61B5/15113 , A61B5/15117 , A61B5/15119 , A61B5/15128 , A61B5/1519 , A61B5/15194
摘要： A microsampler puncturing system for collecting a body fluid from a body part is described, comprising a sample collection unit having a piercing element, and a puncturing instrument having a drive, by which a sample collection unit is movable on a movement path for piercing the piercing element into the skin of the body part and withdrawing it in a piercing and retraction movement, a setting device for setting the puncturing depth of the piercing wound to be generated, and a control device for controlling the piercing and retraction movement having the following sequentially executed movement phases: a forward phase, a retraction phase, and a collecting phase (S). The setting device is settable independently of the chronological mean of the defined residual puncturing depth (dr), with reference to the collecting phase.
摘要翻译：描述了一种用于从身体部分收集体液的微量取样器穿刺系统，包括具有刺穿元件的样本收集单元和具有驱动器的穿刺器械，通过该穿刺器具，样本收集单元可在用于刺穿穿孔的移动路径上移动元件进入身体部分的皮肤并且在穿刺和收缩运动中取出，用于设定要产生的穿刺伤口的穿刺深度的设置装置，以及用于控制穿刺和缩回运动的控制装置，其具有以下顺序执行移动阶段：前进阶段，退回阶段和收集阶段（S）。参考收集阶段，设定装置可独立于定义的残留穿刺深度（dr）的时间平均值来设定。

4. 发明申请

US20100094172A1 Test system for measuring the concentration of an analyte in a body fluid 有权
标题翻译：用于测量体液中分析物浓度的测试系统
公开(公告)号：US20100094172A1
公开(公告)日：2010-04-15
申请号：US12619384
申请日：2009-11-16
申请人： Hans List , Hans-Peter Haar , George Bevan Kirby Meacham
发明人： Hans List , Hans-Peter Haar , George Bevan Kirby Meacham
IPC分类号： A61B5/151
CPC分类号： A61B5/150198 , A61B5/150022 , A61B5/150358 , A61B5/150419 , A61B5/150511 , A61B5/15107 , A61B5/15117 , A61B5/15146 , A61B5/15151 , A61B5/15161 , A61B5/15176
摘要： An actuator for driving a test element is disclosed. The test element can comprise a lancet for perforating the skin of a living organism. The actuator can comprise an engaging part for engaging and driving the test element in a lancing motion. The actuator can further comprise a lancing actuator and a lancing spring. The lancing actuator can bias the lancing spring by executing a forward movement and thereby can exert a biasing force on the engaging part. The actuator can further comprise a latch element. The latch element can be a force-sensitive latch element for exerting a retention force to hold back the engaging part. The retention force can counteract the biasing force. The latch element can release the engaging part when the biasing force exerted by the lancing actuator exceeds the retention force exerted by the latch element, thereby allowing the test element to perform the lancing motion.
摘要翻译：公开了用于驱动测试元件的致动器。测试元件可以包括用于穿孔活体的皮肤的刺血针。致动器可以包括用于以穿刺运动接合和驱动测试元件的接合部分。致动器还可包括穿刺致动器和穿刺弹簧。穿刺致动器可以通过执行向前运动来偏压穿刺弹簧，从而可以在接合部件上施加偏置力。致动器还可以包括闩锁元件。闩锁元件可以是用于施加保持力以阻止接合部分的力敏锁定元件。保持力可以抵消偏置力。当由穿刺致动器施加的偏压力超过由闩锁元件施加的保持力时，闩锁元件可以释放接合部件，从而允许测试元件执行穿刺运动。

5. 发明申请

US20060122536A1 Direct monitoring of interstitial fluid composition 审中-公开
标题翻译：直接监测间质液组成
公开(公告)号：US20060122536A1
公开(公告)日：2006-06-08
申请号：US11283362
申请日：2005-11-18
申请人： Hans-Peter Haar , Hans List , George Bevan Kirby Meacham
发明人： Hans-Peter Haar , Hans List , George Bevan Kirby Meacham
IPC分类号： A61D5/00 , A61B5/00
CPC分类号： A61B5/1455 , A61B5/14514 , A61B5/14532 , A61B10/0045 , A61B2010/008
摘要： The present invention generally relates to a system for sampling body fluids. In particular, the system has an implantable catheter for introduction into a tissue, a pump for transporting a volume of the body fluid out of the catheter, a volume determination unit for determining the volume of fluid and a control means for controlling the pump means based on the determined volume of body fluid.
摘要翻译：本发明一般涉及用于体液取样的系统。特别地，该系统具有用于引入组织的可植入导管，用于将一定体积的体液输送出导管的泵，用于确定流体体积的体积确定单元和用于控制泵装置的控制装置对体液体积的确定。

6. 发明申请

US20050131342A1 Needleless hypodermic injection system, application device and medication cartridge therefor 审中-公开
标题翻译：无针皮下注射系统，应用装置及药筒
公开(公告)号：US20050131342A1
公开(公告)日：2005-06-16
申请号：US11049503
申请日：2005-02-02
申请人： Hans-Peter Haar , George Bevan Kirby Meacham , Konrad Popp , Otto Bruntrup , Ulrich Riemensperger , Guenter Ihle , Bruno Thos , Hans List , Dirk Bandau , Horst Engelhardt , Christian Gliewe
发明人： Hans-Peter Haar , George Bevan Kirby Meacham , Konrad Popp , Otto Bruntrup , Ulrich Riemensperger , Guenter Ihle , Bruno Thos , Hans List , Dirk Bandau , Horst Engelhardt , Christian Gliewe
IPC分类号： A61M5/142 , A61M5/20 , A61M5/24 , A61M5/30 , A61M5/31 , A61M5/50 , A61M35/00
CPC分类号： A61M5/30 , A61M5/2046 , A61M5/2425 , A61M5/3129 , A61M5/5086 , A61M2005/2013 , A61M2005/3118 , A61M2005/312 , A61M2205/582 , A61M2205/583
摘要： A needleless hypodermic injection system for injecting a liquid medication, which system comprises a disposable cartridge which contains a medication and which comprises a propellant and an igniter, and a reusable application device which comprises a pressure chamber for receiving the medication cartridge, actuation means including an ignition system and means for ensuring reliability and safety of the system. The reusable application device comprises: (a) a housing including a fist housing section and a second housing section which are adapted to be assembled together by a screwing operation, the first housing section comprising a front part having an injection outlet and a chamber adapted to receive a the cartridge contains the medication to be injected and also contains a propellant and an igniter, and (b) means for selectively activating said igniter of said cartridge when predetermined conditions are fulfilled.
摘要翻译：一种用于注射液体药物的无针刺皮下注射系统，该系统包括含有药物并且包括推进剂和点火器的一次性药筒，以及包括用于接收药物盒的压力室的可重复使用的施用装置，致动装置包括点火系统和确保系统可靠性和安全性的手段。可重复使用的应用装置包括：（a）包括第一壳体部分和第二壳体部分的壳体，其适于通过旋拧操作而组装在一起，所述第一壳体部分包括具有注射出口的前部部分和适于接收包含要注射的药物的药筒并且还包含推进剂和点火器，以及（b）用于在满足预定条件时选择性地启动所述药筒的点火器的装置。

7. 发明授权

US08251922B2 Analysis system for automatic skin prick analysis 有权
标题翻译：自动皮肤点刺分析系统
公开(公告)号：US08251922B2
公开(公告)日：2012-08-28
申请号：US12755839
申请日：2010-04-07
申请人： Hans List , Hans-Peter Haar , George Bevan Kirby Meacham
发明人： Hans List , Hans-Peter Haar , George Bevan Kirby Meacham
IPC分类号： A61B5/00 , B65D81/00
CPC分类号： A61B5/150198 , A61B5/150022 , A61B5/150358 , A61B5/150419 , A61B5/150519 , A61B5/15113 , A61B5/15117 , A61B5/15128 , A61B5/15146 , A61B5/15151 , A61B5/15163 , A61B5/15176 , A61B5/157
摘要： Analysis system for automatically performing a skin prick analysis by pricking the skin for producing a sample of body liquid and detecting an analyte contained in the sample. The analysis system comprises a magazine with a plurality of compartments each containing a lancing element and an analysis element, and a reusable hand-held instrument having a drive assembly. The drive assembly is adapted for driving at least the following movements by manually generated mechanical force: a coupling movement by which one of the lancing elements is coupled to the drive assembly; a puncturing and sample collection movement of one of the lancing elements contained in the magazine and coupled to the drive assembly; and a remaganizing movement by which the test element is transported back into the compartment of the magazine.
摘要翻译：用于通过穿刺皮肤以产生体液样品并检测样品中包含的分析物来自动执行皮肤点刺分析的分析系统。分析系统包括具有多个隔室的盒，每个隔间包含穿刺元件和分析元件，以及具有驱动组件的可重复使用的手持式器械。所述驱动组件适于通过手动产生的机械力来至少驱动以下运动：联接运动，通过所述联接运动，所述穿刺元件中的一个联接到所述驱动组件; 穿刺和样本收集运动，其中包含在所述盒中的所述穿刺元件之一并且联接到所述驱动组件; 以及将测试元件运送回料仓的隔间的再现运动。

8. 发明授权

US08114029B2 Test system for measuring the concentration of an analyte in a body fluid 有权
标题翻译：用于测量体液中分析物浓度的测试系统
公开(公告)号：US08114029B2
公开(公告)日：2012-02-14
申请号：US12619384
申请日：2009-11-16
申请人： Hans List , Hans-Peter Haar , George Bevan Kirby Meacham
发明人： Hans List , Hans-Peter Haar , George Bevan Kirby Meacham
IPC分类号： A61B5/00 , A61B17/14 , A61B17/32
CPC分类号： A61B5/150198 , A61B5/150022 , A61B5/150358 , A61B5/150419 , A61B5/150511 , A61B5/15107 , A61B5/15117 , A61B5/15146 , A61B5/15151 , A61B5/15161 , A61B5/15176
摘要： An actuator for driving a test element is disclosed. The test element can comprise a lancet for perforating the skin of a living organism. The actuator can comprise an engaging part for engaging and driving the test element in a lancing motion. The actuator can further comprise a lancing actuator and a lancing spring. The lancing actuator can bias the lancing spring by executing a forward movement and thereby can exert a biasing force on the engaging part. The actuator can further comprise a latch element. The latch element can be a force-sensitive latch element for exerting a retention force to hold back the engaging part. The retention force can counteract the biasing force. The latch element can release the engaging part when the biasing force exerted by the lancing actuator exceeds the retention force exerted by the latch element, thereby allowing the test element to perform the lancing motion.
摘要翻译：公开了用于驱动测试元件的致动器。测试元件可以包括用于穿孔活体的皮肤的刺血针。致动器可以包括用于以穿刺运动接合和驱动测试元件的接合部分。致动器还可包括穿刺致动器和穿刺弹簧。穿刺致动器可以通过执行向前运动来偏压穿刺弹簧，从而可以在接合部件上施加偏置力。致动器还可以包括闩锁元件。闩锁元件可以是用于施加保持力以阻止接合部分的力敏锁定元件。保持力可以抵消偏置力。当由穿刺致动器施加的偏压力超过由闩锁元件施加的保持力时，闩锁元件可以释放接合部件，从而允许测试元件执行穿刺运动。

9. 发明申请

US20110092855A1 Analysis system for automatic skin prick analysis 有权
标题翻译：自动皮肤点刺分析系统
公开(公告)号：US20110092855A1
公开(公告)日：2011-04-21
申请号：US12755839
申请日：2010-04-07
申请人： Hans List , Hans-Peter Haar , George Bevan Kirby Meacham
发明人： Hans List , Hans-Peter Haar , George Bevan Kirby Meacham
IPC分类号： A61B5/00 , A61B17/32
CPC分类号： A61B5/150198 , A61B5/150022 , A61B5/150358 , A61B5/150419 , A61B5/150519 , A61B5/15113 , A61B5/15117 , A61B5/15128 , A61B5/15146 , A61B5/15151 , A61B5/15163 , A61B5/15176 , A61B5/157
摘要： Analysis system for automatically performing a skin prick analysis by pricking the skin for producing a sample of body liquid and detecting an analyte contained in the sample. The analysis system comprises a magazine with a plurality of compartments each containing a lancing element and an analysis element, and a reusable hand-held instrument having a drive assembly. The drive assembly is adapted for driving at least the following movements by manually generated mechanical force: a coupling movement by which one of the lancing elements is coupled to the drive assembly; a puncturing and sample collection movement of one of the lancing elements contained in the magazine and coupled to the drive assembly; and a remaganizing movement by which the test element is transported back into the compartment of the magazine.
摘要翻译：用于通过穿刺皮肤以产生体液样品并检测样品中包含的分析物来自动执行皮肤点刺分析的分析系统。分析系统包括具有多个隔室的盒，每个隔间包含穿刺元件和分析元件，以及具有驱动组件的可重复使用的手持式器械。所述驱动组件适于通过手动产生的机械力来至少驱动以下运动：联接运动，通过所述联接运动，所述穿刺元件中的一个联接到所述驱动组件; 穿刺和样本收集运动，其中包含在所述盒中的所述穿刺元件之一并且联接到所述驱动组件; 以及将测试元件运送回料仓的隔间的再现运动。

10. 发明申请

US20080262388A1 Puncturing System For Collecting Body Fluid Sample 有权
标题翻译：用于收集体液样品的穿刺系统
公开(公告)号：US20080262388A1
公开(公告)日：2008-10-23
申请号：US12122908
申请日：2008-05-19
申请人： Hans List , Hans-Peter Haar , George Bevan Kirby Meacham , Michael Eusemann
发明人： Hans List , Hans-Peter Haar , George Bevan Kirby Meacham , Michael Eusemann
IPC分类号： A61B5/15
CPC分类号： A61B5/15196 , A61B5/14514 , A61B5/150022 , A61B5/150152 , A61B5/150175 , A61B5/15019 , A61B5/150419 , A61B5/150519 , A61B5/15113 , A61B5/15117 , A61B5/15119 , A61B5/15128 , A61B5/1519 , A61B5/15194
摘要： The invention relates to a microsampler puncturing system for collecting a body fluid from a body part, comprising a sample collection unit having a piercing element, and a puncturing instrument having a drive, by which a sample collection unit is movable on a movement path for piercing the piercing element into the skin of the body part and withdraw it again by means of a piercing and retraction movement, a setting device for setting the puncturing depth of the piercing wound to be generated, and a control device for controlling the piercing and retraction movement having the following sequentially executed movement phases: a forward phase (V), in which the piercing element is pierced up to a defined puncturing depth (dm), a retraction phase (R1), in which the piercing element is partially retracted by a retraction distance (Δd) and is decelerated toward the end of the retraction phase (R1), so that it remains projecting into the skin at a defined residual puncturing depth (dr), and a collecting phase (S), in which the piercing element projects into the skin and a body fluid sample is absorbed by the sample collection unit. The setting device is adapted for the defined puncturing depth is settable independently of the chronological mean of the defined residual puncturing depth (dr), with reference to the collecting phase.
摘要翻译：本发明涉及一种用于从身体部分收集体液的微量取样器穿刺系统，包括具有穿刺元件的样本收集单元和具有驱动器的穿刺器械，通过该穿刺器具，样本收集单元可在用于穿刺的移动路径上移动刺穿元件进入身体部分的皮肤并通过穿刺和缩回运动再次撤回，用于设定要产生穿刺伤口的穿刺深度的设置装置，以及用于控制穿刺和缩回运动的控制装置具有以下顺序执行的移动阶段：穿刺元件被刺穿到限定的穿刺深度（dm）的正向相（V），其中穿刺元件被部分地缩回的收回相位（R 1）缩回距离（Deltad）并且朝向收缩阶段（R 1）的端部减速，使得其以限定的残余穿刺深度（dr）保持突出到皮肤中）和收集阶段（S），其中穿刺元件伸入皮肤并且体液样品被样品收集单元吸收。该设定装置适用于所设定的穿刺深度，可以独立于规定的残留穿刺深度（dr）的时间平均值参照收集阶段进行设定。

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