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1. 发明授权

US06713137B1 Medical containers 失效
标题翻译：医疗容器
公开(公告)号：US06713137B1
公开(公告)日：2004-03-30
申请号：US09448922
申请日：1999-11-23
申请人： Gunnar Andersson , Vittorio Sala
发明人： Gunnar Andersson , Vittorio Sala
IPC分类号： B32B2732
CPC分类号： B32B27/32 , Y10T428/1334 , Y10T428/1352 , Y10T428/2495 , Y10T428/2826 , Y10T428/31913
摘要： The present invention relates to a flexible polyolefin multilayered film for preparation of medical containers by self sealing, comprising at least a first outer layer and a second layer, each of the layers consisting essentially only of one or more polypropylene based polymers selected from the group consisting of polypropylene homopolymers, polypropylene copolymers having randomly distribute ethylene units and mixtures of said homopolymers and said copolymers, wherein said second layer has a melting point in the range between 120° C. and 150°, said first outer layer has a lower flexibility and a higher melting point than said second layer, and said second comprises a polypropylene polyethylene copolymer with a higher amount of ethylene units than said outer layer. The present invention also relates to medical containers made of or comprising the above film.
摘要翻译：本发明涉及一种用于通过自密封制备医疗容器的柔性聚烯烃多层膜，其包括至少第一外层和第二层，每个层基本上仅由一种或多种聚丙烯基聚合物组成，所述聚丙烯基聚合物选自的聚丙烯均聚物，具有随机分布乙烯单元的聚丙烯共聚物和所述均聚物和所述共聚物的混合物，其中所述第二层的熔点在120℃至150℃的范围内，所述第一外层具有较低的柔性和比所述第二层高的熔点，而所述第二层包括具有比所述外层更高量的乙烯单元的聚丙烯聚乙烯共聚物。本发明还涉及由上述膜制成或包含上述膜的医疗容器。

2. 发明申请

US20120122144A1 METHODS EMPLOYING INSECT MODELS FOR DETERMINING INTESTINAL ABSORPTION OF CHEMICAL COMPOUNDS 有权
标题翻译：用于确定化学化合物的吸收吸收的方法
公开(公告)号：US20120122144A1
公开(公告)日：2012-05-17
申请号：US13387083
申请日：2010-08-10
申请人： Peter Aadal Nielsen , Gunnar Andersson , Olga Andersson
发明人： Peter Aadal Nielsen , Gunnar Andersson , Olga Andersson
IPC分类号： C12Q1/02 , A01K67/00
CPC分类号： G01N33/5085
摘要： There is provided insect screening models to determine gastrointestinal absorption of different chemical compounds in vertebrates, and in particular humans, in order to improve the compound screening procedures/processes in the early drug discovery process. This offers many advantages relative to prior technologies since insect models are more reliable tools for the decision-making process than the existing in vitro models, and will speed up the drug screening process and reduce the late phase attrition rate. Moreover, it will reduce the number of mammals sacrificed during the drug discovery phase.
摘要翻译：为了改善早期药物发现过程中的化合物筛选程序/过程，提供了用于确定脊椎动物，特别是人类中不同化合物的胃肠道吸收的昆虫筛选模型。与现有技术相比，昆虫模型是决策过程的可靠工具，而不仅仅是现有的体外模型，因此与现有技术相比具有很多优势，并且将加速药物筛选过程并降低后期的磨耗率。此外，它将减少在药物发现阶段牺牲的哺乳动物的数量。

3. 发明申请

US20110171682A1 SCREENING METHODS EMPLOYING INSECTS WITH BLOOD BRAIN BARRIER 有权
标题翻译：使用血液脑屏障的筛选方法
公开(公告)号：US20110171682A1
公开(公告)日：2011-07-14
申请号：US13060619
申请日：2009-09-16
申请人： Peter Aadal Nielsen , Gunnar Andersson
发明人： Peter Aadal Nielsen , Gunnar Andersson
IPC分类号： C12Q1/24 , C12Q1/02
CPC分类号： G01N33/5085
摘要： There is provided insect models that are aimed to reflect vertebrate blood-brain barrier (BBB) penetration. Investigation of BBB penetration is extremely important in drug discovery; successful CNS drugs have to cross the BBB, while BBB penetration may cause unwanted side effects for peripheral acting drugs. Specifically, the present invention relates to the use of insects in screening for substances with a biological effect on the brain or central nervous system and/or effect on a disease or disorder of the brain or central nervous system. It further relates to use of such insects in screening for substances that have a desired biological activity and which do not cross the blood brain barrier.
摘要翻译：提供旨在反映脊椎动物血脑屏障（BBB）渗透的昆虫模型。 BBB穿透的调查在药物发现中是非常重要的; 成功的CNS药物必须穿过BBB，而BBB渗透可能会对外周作用药物造成不良副作用。具体地，本发明涉及昆虫在对脑或中枢神经系统具有生物学作用的物质的筛选和/或对脑或中枢神经系统疾病或病症的影响中的应用。它进一步涉及这种昆虫在筛选具有所需生物学活性并且不会穿过血脑屏障的物质的用途。

4. 发明申请

US20070225945A1 Control system for a transformer or reactor 有权
标题翻译：变压器或电抗器的控制系统
公开(公告)号：US20070225945A1
公开(公告)日：2007-09-27
申请号：US11385434
申请日：2006-03-21
申请人： Bengt-Olof Stenestam , Gunnar Andersson
发明人： Bengt-Olof Stenestam , Gunnar Andersson
IPC分类号： G06F19/00 , G06F17/40
CPC分类号： G01R31/3274 , G01R31/027 , H01F29/04 , H01H2009/0061 , H02H7/055
摘要： A universal control and diagnostic system for a transformer that may be retrofit with existing control and tap-changer equipment, the system providing for remote monitoring and control of the equipment and for measuring various criteria associated with the tap-changer to substantially minimize damage to the equipment during a maneuver and for substantially avoiding carbonization of a connected contact.
摘要翻译：用于变压器的通用控制和诊断系统，可以使用现有的控制和分接开关设备进行改造，该系统提供对设备的远程监控和控制，并用于测量与分接开关相关的各种标准，从而大大减少对在机动操作期间设备，并大大避免连接的接触件的碳化。

5. 发明授权

US07089145B2 Tap changer condition diagnosing 有权
标题翻译：分接开关状态诊断
公开(公告)号：US07089145B2
公开(公告)日：2006-08-08
申请号：US10450578
申请日：2001-12-14
申请人： Bengt-Olof Stenestam , Gunnar Andersson
发明人： Bengt-Olof Stenestam , Gunnar Andersson
IPC分类号： G01K1/00
CPC分类号： G01R31/027 , G01R31/3274 , G01R31/333 , H01F29/04 , H01H2009/0061
摘要： A method and apparatus for condition diagnosing of a tap changer immersed in a cooling fluid, controlling and regulating an inductive power device, such as a transformer or reactor. The diagnosing method compares and evaluates expected heat exchanges between the tap changer and ambient air and the inductive power device, an expected amount of heat generated by the tap changer during operation, together with an actual temperature of the fluid. From the actual temperature, expected heat exchanges and expected generated heat, the heat balance in the system may be obtained and is used for disgnosing the operation conditions of the tap changer. The results from the condition diagnosing may be used as indicators that can alarm operators or may be sent as a data signal to remote and/or portable display means, such as a computer.
摘要翻译：用于状态诊断浸入冷却流体中的抽头变换器的方法和装置，控制和调节诸如变压器或反应器的感应功率器件。诊断方法比较和评估分接开关与环境空气和感应功率器件之间期望的热交换，在分接开关在运行期间产生的预期热量以及流体的实际温度。从实际的温度，预期的热交换和期望的产生的热量，可以获得系统中的热平衡，并用于断开分接开关的操作条件。来自状态诊断的结果可以用作可以将报警操作者或作为数据信号发送到诸如计算机的远程和/或便携式显示装置的指示器。

6. 发明授权

US5914413A Gas filter unit 失效
标题翻译：气体过滤器单元
公开(公告)号：US5914413A
公开(公告)日：1999-06-22
申请号：US930377
申请日：1997-10-23
申请人： Gunnar Andersson , Bo Engvall , Bo Lindvert , Goran Strom
发明人： Gunnar Andersson , Bo Engvall , Bo Lindvert , Goran Strom
IPC分类号： B01D46/02 , B01D29/13
CPC分类号： B01D46/023 , B01D46/02 , Y10S55/12 , Y10S55/31
摘要： The invention concerns a gas filter unit or cartridge type, including a filter material put together to form one or several filter bags, and a support frame of essentially U-shaped cross-sectional configuration, including a web portion and two lateral leg members in adjoining relationship, the filter material closest to the mouths of the filter bags being clamped in position between said lateral leg members. In accordance with the invention, the frame includes profile sections of a flexible material, preferably a plastics material, at least one of said lateral leg members being hingedly interconnected with the web portion, in addition to which locking means are provided to retain the corresponding lateral leg member in its clamping position in which it is pivoted into engagement with the other lateral leg member.
摘要翻译： PCT No.PCT / SE96 / 00354 Sec。 371日期：1997年10月23日 102（e）日期1997年10月23日PCT 1996年3月21日PCT公布。公开号WO96 / 29138 日期1996年9月26日本发明涉及一种气体过滤器单元或盒式，包括放置在一起以形成一个或多个过滤袋的过滤材料，以及基本上呈U形横截面构造的支撑框架，包括腹板部分和两个相邻关系的侧腿部件，最靠近过滤袋口部的过滤材料被夹持在所述侧腿部件之间。根据本发明，框架包括柔性材料的轮廓部分，优选为塑料材料，所述横向腿部构件中的至少一个与腹板部分铰接地互连，除此之外还设有锁定装置以保持相应的侧面腿部构件处于其夹紧位置，在该位置中，该构件枢转成与另一侧向腿构件接合。

7. 发明授权

US5565455A Method for treating substance abuse disorders 失效
标题翻译：治疗药物滥用障碍的方法
公开(公告)号：US5565455A
公开(公告)日：1996-10-15
申请号：US325212
申请日：1994-11-30
申请人： Anders Bjork , Gunnar Andersson
发明人： Anders Bjork , Gunnar Andersson
IPC分类号： C07D295/18 , A61K31/44 , A61K31/4427 , A61K31/445 , A61K31/495 , A61K31/496 , A61K31/505 , A61K31/535 , A61K31/5355 , A61K31/5375 , A61P25/30 , A61P43/00 , C07D211/14 , C07D213/74 , C07D213/80 , C07D239/42 , C07D401/06 , C07D403/06
CPC分类号： A61K31/495 , Y10S514/81 , Y10S514/811 , Y10S514/812 , Y10S514/813
摘要： A method for relief or prevention of a withdrawal syndrome resulting from addiction to a drug or substance of abuse and/or for the suppression of dependence on drugs or substances of abuse which comprises administering to a patient in need thereof an effective amount of a bisphenylalkylpiperazinde derivative, wherein said withdrawal syndrome comprises at least one of the symptoms selected from the group consisting of sleep disturbance, mood disturbance, and craving for the drug or substance of abuse.
摘要翻译： PCT No.PCT / SE93 / 00339 Sec。 371日期1994年11月30日 102（e）日期1994年11月30日PCT 1993年4月19日PCT公布。公开号WO93 / 20821 日期1993年10月28日一种用于缓解或预防因滥用药物或物质成瘾引起的戒断综合症和/或抑制对药物或滥用物质的依赖的方法，其包括对有需要的患者施用有效的双苯基烷基哌嗪衍生物的量，其中所述戒断综合征包括选自以下的症状中的至少一种：睡眠障碍，情绪障碍，以及对药物或滥用物质的渴望。

8. 发明申请

US20140154725A1 INSECT-BASED EX VIVO MODEL FOR TESTING BLOOD-BRAIN BARRIER PENETRATION AND METHOD FOR EXPOSING INSECT BRAIN TO NANOPARTICLES 有权
标题翻译：用于测试血脑屏障穿刺的基于INSECT的VIVO模型和将脑膜暴露于纳米颗粒的方法
公开(公告)号：US20140154725A1
公开(公告)日：2014-06-05
申请号：US13881566
申请日：2011-09-30
申请人： Peter Aadal Nielsen , Gunnar Andersson , Olga Andersson
发明人： Peter Aadal Nielsen , Gunnar Andersson , Olga Andersson
IPC分类号： G01N33/50
CPC分类号： G01N33/5058 , G01N33/5085
摘要： There is provided an ex-vivo insect screening model to accurately determine blood-brain barrier penetration of different nanoparticles in order to improve the compound screening procedures/processes in the early drug discovery process. This object offers many advantages relative to prior technologies since insect models are more reliable tools for the decision-making process than the existing in vitro models, and will speed up the drug screening process and reduce the late phase attrition rate. Moreover, it will reduce the number of mammals sacrificed during the drug discovery phase.
摘要翻译：提供了一种离体昆虫筛选模型，以准确地确定不同纳米颗粒的血脑屏障穿透，以改善早期药物发现过程中的复合筛选程序/过程。与现有技术相比，该目标提供了许多优点，因为昆虫模型是决策过程中比现有体外模型更可靠的工具，并且将加速药物筛选过程并减少后期磨耗率。此外，它将减少在药物发现阶段牺牲的哺乳动物的数量。

9. 发明申请

US20120122145A1 INSECT-BASED EX VIVO MODEL FOR TESTING BLOOD-BRAIN BARRIER PENETRATION AND METHOD FOR EXPOSING INSECT BRAIN TO CHEMICAL COMPOUNDS 有权
标题翻译：用于测试血脑屏障穿刺的基于INSECT的VIVO模型和将化学物质暴露于化学化合物的方法
公开(公告)号：US20120122145A1
公开(公告)日：2012-05-17
申请号：US13387088
申请日：2010-08-10
申请人： Peter Aadal , Gunnar Andersson , Olga Andersson
发明人： Peter Aadal , Gunnar Andersson , Olga Andersson
IPC分类号： C12Q1/02 , A01K67/00
CPC分类号： G01N33/5085
摘要： There is provided an ex-vivo insect screening model to accurately determine blood-brain barrier penetration of different chemical compounds in order to improve the compound screening procedures/processes in the early drug discovery process. This object offers many advantages relative to prior technologies since insect models are more reliable tools for the decision-making process than the existing in vitro models, and will speed up the drug screening process and reduce the late phase attrition rate. Moreover, it will reduce the number of mammals sacrificed during the drug discovery phase.
摘要翻译：提供了一种离体昆虫筛选模型，以准确确定不同化合物的血脑屏障渗透，以改善早期药物发现过程中的复合筛选程序/过程。与现有技术相比，该目标提供了许多优点，因为昆虫模型是决策过程中比现有体外模型更可靠的工具，并且将加速药物筛选过程并减少后期磨耗率。此外，它将减少在药物发现阶段牺牲的哺乳动物的数量。

10. 发明授权

US07444266B2 Control system for a transformer or reactor 有权
标题翻译：变压器或电抗器的控制系统
公开(公告)号：US07444266B2
公开(公告)日：2008-10-28
申请号：US11385434
申请日：2006-03-21
申请人： Bengt-Olof Stenestam , Gunnar Andersson
发明人： Bengt-Olof Stenestam , Gunnar Andersson
IPC分类号： G06F11/30 , G06F15/00 , G21C17/00
CPC分类号： G01R31/3274 , G01R31/027 , H01F29/04 , H01H2009/0061 , H02H7/055
摘要： A universal control and diagnostic system for a transformer that may be retrofit with existing control and tap-changer equipment, the system providing for remote monitoring and control of the equipment and for measuring various criteria associated with the tap-changer to substantially minimize damage to the equipment during a maneuver and for substantially avoiding carbonization of a connected contact.
摘要翻译：用于变压器的通用控制和诊断系统，可以使用现有的控制和分接开关设备进行改造，该系统提供对设备的远程监控和控制，并用于测量与分接开关相关的各种标准，从而大大减少对在机动操作期间设备，并大大避免连接的接触件的碳化。

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