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1. 发明申请

US20100270898A1 Displacement device for pivotally held separation elements and article of furniture 有权
标题翻译：用于枢转保持的分离元件和家具的位移装置
公开(公告)号：US20100270898A1
公开(公告)日：2010-10-28
申请号：US12662684
申请日：2010-04-28
申请人： Gregor Haab , Martin Frei , Alfred Stutz , Rolf Heisig , Wladyslaw Wasilewski
发明人： Gregor Haab , Martin Frei , Alfred Stutz , Rolf Heisig , Wladyslaw Wasilewski
IPC分类号： E05D15/06 , A47B96/20
CPC分类号： E06B3/5045 , E05D15/0634 , E05D15/58 , E05Y2201/638 , E05Y2201/64 , E05Y2201/702 , E05Y2600/20 , E05Y2900/212 , Y10T16/364 , Y10T16/3825 , Y10T16/3834 , Y10T16/547 , Y10T16/5478
摘要： The displacement device serves to hold a separation element, which is pivotally connected to a bracket, which is held slideably by a first beam of a scissor assembly and firmly by a second beam of the scissor assembly with a scissor assembly bearing. The scissor assembly bearing comprises a profile body that is adapted to the bracket and can be connected thereto, which profile body comprises a profile part which is connected articulated to the first end element of an adjusting lever, of which the second end element is connected on the one hand pivotally with the second beam and on the other hand is held by an adjusting bolt, of which the threaded shank is rotatably mounted in a threaded channel of the profile body.
摘要翻译：位移装置用于保持分离元件，该分离元件枢转地连接到支架，该支架可被剪刀组件的第一梁可滑动地固定，并且具有用剪刀组件轴承的第二剪刀组件。剪刀组件轴承包括适于支架并可连接到其上的轮廓体，该轮廓体包括轮廓部分，该轮廓部分铰接到调节杆的第一端部元件上，第二端部元件连接在该调节杆上一方面与第二梁枢轴转动，另一方面由调节螺栓保持，其中螺纹杆可旋转地安装在轮廓体的螺纹通道中。

2. 发明授权

US08336972B2 Displacement device for pivotally held separation elements and article of furniture 有权
标题翻译：用于枢转保持的分离元件和家具的位移装置
公开(公告)号：US08336972B2
公开(公告)日：2012-12-25
申请号：US12662684
申请日：2010-04-28
申请人： Gregor Haab , Martin Frei , Alfred Stutz , Rolf Heisig , Wladyslaw Wasilewski
发明人： Gregor Haab , Martin Frei , Alfred Stutz , Rolf Heisig , Wladyslaw Wasilewski
IPC分类号： A47B96/00
CPC分类号： E06B3/5045 , E05D15/0634 , E05D15/58 , E05Y2201/638 , E05Y2201/64 , E05Y2201/702 , E05Y2600/20 , E05Y2900/212 , Y10T16/364 , Y10T16/3825 , Y10T16/3834 , Y10T16/547 , Y10T16/5478
摘要： The displacement device serves to hold a separation element, which is pivotally connected to a bracket, which is held slideably by a first beam of a scissor assembly and firmly by a second beam of the scissor assembly with a scissor assembly bearing. The scissor assembly bearing comprises a profile body that is adapted to the bracket and can be connected thereto, which profile body comprises a profile part which is connected articulated to the first end element of an adjusting lever, of which the second end element is connected on the one hand pivotally with the second beam and on the other hand is held by an adjusting bolt, of which the threaded shank is rotatably mounted in a threaded channel of the profile body.
摘要翻译：位移装置用于保持分离元件，该分离元件枢转地连接到支架，该支架可被剪刀组件的第一梁可滑动地固定，并且具有用剪刀组件轴承的第二剪刀组件。剪刀组件轴承包括适于支架并可连接到其上的轮廓体，该轮廓体包括轮廓部分，该轮廓部分铰接到调节杆的第一端部元件上，第二端部元件连接在该调节杆上一方面与第二梁枢轴转动，另一方面由调节螺栓保持，其中螺纹杆可旋转地安装在轮廓体的螺纹通道中。

3. 发明申请

US20100269291A1 Carriage for holding a separation element and separation element 有权
标题翻译：用于保持分离元件和分离元件的支架
公开(公告)号：US20100269291A1
公开(公告)日：2010-10-28
申请号：US12662688
申请日：2010-04-28
申请人： Gregor Haab , Martin Frei , Alfred Stutz
发明人： Gregor Haab , Martin Frei , Alfred Stutz
IPC分类号： E05D15/06
CPC分类号： E06B3/5045 , E05D15/0634 , E05D15/58 , E05Y2201/638 , E05Y2201/64 , E05Y2201/702 , E05Y2600/20 , E05Y2900/212 , Y10T16/364 , Y10T16/3825 , Y10T16/3834 , Y10T16/547 , Y10T16/5478
摘要： The carriage, which serves for holding a slidable separation element, comprises a carriage body and at least one running wheel, which is a rolling along a rail when the separation elements is displaced. According to the invention the carriage body comprises a housing with an interior space, in which an adjusting element is provided, which is protruding through an opening out of the housing and which is seated slidable in a direction at least approximately vertically to the running direction of the carriage, and which adjusting element comprises a holding element that interacts within the housing with an adjusting element, that is displaceable in relation to the holding element by means of an adjusting screw, which is held by the carriage body, so that the adjustment element is held at a selected position, whereas either the part of the adjusting element that is protruding out of the housing is provided with the at least one running wheel and the carriage body is connected to the separation element; or the part of the adjusting element that is protruding out of the housing is connected to the separation element and the carriage body is provided with the at least one running wheel.
摘要翻译：用于保持可滑动分离元件的滑架包括滑架主体和至少一个运行轮，当分离元件移位时，该行走轮沿轨道滚动。根据本发明，滑架主体包括具有内部空间的壳体，其中设置有调节元件，调节元件通过开口离开壳体突出，并且该调节元件可以在至少大致垂直于垂直于滑架，以及哪个调节元件包括与壳体内的相互作用的调节元件，该调节元件可通过由滑架主体保持的调节螺钉相对于保持元件移动，使得调节元件被保持在选定位置，而从壳体突出的调节元件的一部分设置有至少一个行走轮，并且滑架主体连接到分离元件; 或者从壳体突出的调节元件的一部分连接到分离元件，并且滑架主体设置有至少一个行进轮。

4. 发明授权

US08522398B2 Carriage for holding a separation element and separation element 有权
标题翻译：用于保持分离元件和分离元件的支架
公开(公告)号：US08522398B2
公开(公告)日：2013-09-03
申请号：US12662688
申请日：2010-04-28
申请人： Gregor Haab , Martin Frei , Alfred Stutz
发明人： Gregor Haab , Martin Frei , Alfred Stutz
IPC分类号： E05D15/16
CPC分类号： E06B3/5045 , E05D15/0634 , E05D15/58 , E05Y2201/638 , E05Y2201/64 , E05Y2201/702 , E05Y2600/20 , E05Y2900/212 , Y10T16/364 , Y10T16/3825 , Y10T16/3834 , Y10T16/547 , Y10T16/5478
摘要： The carriage, which serves for holding a slidable separation element, comprises a carriage body and at least one running wheel, which is a rolling along a rail when the separation elements is displaced. According to the invention the carriage body comprises a housing with an interior space, in which a holding unit is provided, which is protruding through an opening out of the housing and which is seated slidable in a direction at least approximately vertically to the running direction of the carriage, and which the holding unit comprises a holding element that interacts within the housing with an adjusting element, that is displaceable in relation to the holding element by means of an adjusting screw, which is held by the carriage body, so that the holding unit is held at a selected position, whereas either the part of the holding unit that is protruding out of the housing is provided with the at least one running wheel and the carriage body is connected to the separation element; or the part of the holding unit that is protruding out of the housing is connected to the separation element and the carriage body is provided with the at least one running wheel.
摘要翻译：用于保持可滑动分离元件的滑架包括滑架主体和至少一个运行轮，当分离元件移位时，该行走轮沿轨道滚动。根据本发明，滑架主体包括具有内部空间的壳体，其中设置有保持单元，该保持单元通过开口离开壳体突出，并且其可沿着至少大致垂直于垂直于托架，其中保持单元包括与壳体内的相互作用的保持元件和调节元件，该保持元件可通过由托架本体保持的调节螺钉相对于保持元件移动，从而保持单元被保持在选定位置，而从外壳突出的保持单元的一部分设置有至少一个行走轮，并且滑架主体连接到分离元件; 或者从壳体突出的保持单元的部分连接到分离元件，并且滑架主体设置有至少一个行走轮。

5. 发明授权

US08318936B2 Method for producing N-methylnaltrexone bromide 有权
标题翻译： N-甲基纳曲酮溴化物的制备方法
公开(公告)号：US08318936B2
公开(公告)日：2012-11-27
申请号：US12600341
申请日：2008-05-14
申请人： Ulrich Weigl , Pascal Schär , Alfred Stutz
发明人： Ulrich Weigl , Pascal Schär , Alfred Stutz
IPC分类号： C07D489/08 , C07D489/02
CPC分类号： C07D489/08
摘要： Process for the preparation of N-methylnaltrexone bromide, wherein a compound of the general formula (I): wherein X− represents an anion other than the bromide anion, and R represents hydrogen or a leaving group, is dissolved or dispersed in a suitable polar solvent, the solution or dispersion is mixed with a compound containing bromide anions, and the resulting reaction mixture is stirred until N-methylnaltrexone bromide has formed and crystallized, wherein, in the case where R represents a leaving group, that group is removed during or after the reaction.
摘要翻译：制备N-甲基纳曲酮溴化物的方法，其中通式（I）的化合物：其中X代表除溴阴离子以外的阴离子，R代表氢或离去基团，被溶解或分散在合适的极性将溶液或分散体与含有溴阴离子的化合物混合，并将所得反应混合物搅拌直到形成N-甲基纳曲酮溴化物并结晶，其中在R表示离去基团的情况下，该组在反应后。

6. 发明授权

US09212136B2 Methods for producing paricalcitol 有权
标题翻译：生产帕立骨糖醇的方法
公开(公告)号：US09212136B2
公开(公告)日：2015-12-15
申请号：US13055182
申请日：2009-07-22
申请人： Thomas Bader , Alfred Stutz , Hans-Ulrich Bichsel , Changchun Fu
发明人： Thomas Bader , Alfred Stutz , Hans-Ulrich Bichsel , Changchun Fu
IPC分类号： C07C401/00 , C07C317/18 , C07C323/12
CPC分类号： C07C401/00 , C07C317/18 , C07C323/12
摘要： The present invention is directed to novel processes for the preparation of paricalcitol to novel intermediates used in these processes, and to processes for preparation of the novel intermediates.
摘要翻译：本发明涉及用于制备用于这些方法的新中间体的帕立骨化醇的新方法和用于制备新型中间体的方法。

7. 发明申请

US20110184199A1 Methods For Producing Paricalcitol 有权
标题翻译：生产Paricalcitol的方法
公开(公告)号：US20110184199A1
公开(公告)日：2011-07-28
申请号：US13055182
申请日：2009-07-22
申请人： Thomas Bader , Alfred Stutz , Hans-Ulrich Bichsel , Changchun Fu
发明人： Thomas Bader , Alfred Stutz , Hans-Ulrich Bichsel , Changchun Fu
IPC分类号： C07C401/00
CPC分类号： C07C401/00 , C07C317/18 , C07C323/12
摘要： The present invention is directed to novel processes for the preparation of paricalcitol to novel intermediates used in these processes, and to processes for preparation of the novel intermediates.
摘要翻译：本发明涉及用于制备用于这些方法的新中间体的帕立骨化醇的新方法和用于制备新型中间体的方法。

8. 发明申请

US20100168427A1 METHOD FOR PRODUCING N-METHYLNALTREXONE BROMIDE 有权
标题翻译：生产N-甲基溴化硼的方法
公开(公告)号：US20100168427A1
公开(公告)日：2010-07-01
申请号：US12600341
申请日：2008-05-14
申请人： Ulrich Weigl , Pascal Schär , Alfred Stutz
发明人： Ulrich Weigl , Pascal Schär , Alfred Stutz
IPC分类号： C07D489/08
CPC分类号： C07D489/08
摘要： Process for the preparation of N-methylnaltrexone bromide, wherein a compound of the general formula (I): wherein X− represents an anion other than the bromide anion, and R represents hydrogen or a leaving group, is dissolved or dispersed in a suitable polar solvent, the solution or dispersion is mixed with a compound containing bromide anions, and the resulting reaction mixture is stirred until N-methylnaltrexone bromide has formed and crystallised, wherein, in the case where R represents a leaving group, that group is removed during or after the reaction.
摘要翻译：制备N-甲基纳曲酮溴化物的方法，其中通式（I）的化合物：其中X代表除溴阴离子以外的阴离子，R代表氢或离去基团，被溶解或分散在合适的极性将溶液或分散体与含有溴阴离子的化合物混合，并将所得反应混合物搅拌直到形成N-甲基纳曲酮溴化物并结晶，其中在R表示离去基团的情况下，该组在反应后。

9. 发明授权

US07560575B2 Process for preparation of racemic Nebivolol 失效
标题翻译：制备外消旋奈必洛尔的方法
公开(公告)号：US07560575B2
公开(公告)日：2009-07-14
申请号：US11319287
申请日：2005-12-28
申请人： Thomas Bader , Alfred Stutz , Harald Hofmeier , Hans-Ulrich Bichsel
发明人： Thomas Bader , Alfred Stutz , Harald Hofmeier , Hans-Ulrich Bichsel
IPC分类号： C07D311/58 , C07D407/06
CPC分类号： C07D413/14 , C07D311/58 , C07D407/06
摘要： A process of making racemic [2S*[R*[R*[R*]]]] and [2R*[S*[S*[S*]]]]-(±)α,α′-[iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol] of the compound of the formula (I) and its pure [2S*[R*[R*[R*]]]]- and [2R*[S*[S*[S*]]]]-enantiomer compounds and pharmaceutically acceptable salts thereof.
摘要翻译：制备外消旋[2S * [R * [R * [R *]]]和[2R * [S * [S * [S *]]] - （±）α，α' - [亚氨基亚甲基）]双[6-氟-3,4-二氢-2H-1-苯并吡喃-2-甲醇]及其纯的[2S * [R * [R * [R *] ]] - 和[2R * [S * [S * [S *]]]] - 对映体化合物及其药学上可接受的盐。

10. 发明申请

US20090048457A1 PROCESS FOR PREPARATION OF RACEMIC NEBIVOLOL 审中-公开
标题翻译：制备游离性NEBIVOLOL的方法
公开(公告)号：US20090048457A1
公开(公告)日：2009-02-19
申请号：US12159255
申请日：2006-12-28
申请人： Thomas Bader , Alfred Stutz , Harald Hofmeier , Hans-Ulrich Bichsel
发明人： Thomas Bader , Alfred Stutz , Harald Hofmeier , Hans-Ulrich Bichsel
IPC分类号： C07D407/12
CPC分类号： C07D407/06 , C07D311/58 , C07D413/14
摘要： A process of making racemic [2S*[R*[R*[R*]]]] and [2R*[S*[S*[S*]]]]-(±)α,α′-[iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol] of the compound of the formula (I) and its pure [2S*[R*[R*[R*]]]]- and [2R*[S*[S*[S*]]]]-enantiomer compounds and pharmaceutically acceptable salts thereof.
摘要翻译：制备外消旋[2S * [R * [R * [R *]]]和[2R * [S * [S * [S *]]] - （±）α，α' - [亚氨基亚甲基）]双[6-氟-3,4-二氢-2H-1-苯并吡喃-2-甲醇]及其纯的[2S * [R * [R * [R *] ]] - 和[2R * [S * [S * [S *]]]] - 对映体化合物及其药学上可接受的盐。

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