会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 8. 发明申请
    • COMPACT OPTICAL DETECTION SYSTEM
    • 紧凑光学检测系统
    • US20100227386A1
    • 2010-09-09
    • US12438725
    • 2007-08-24
    • Pavel NeuzilJuergen PipperLukas Novak
    • Pavel NeuzilJuergen PipperLukas Novak
    • C12M1/34G01J1/58
    • G01N21/645B01L3/5088B01L7/52B01L2200/147B01L2300/1827G01N21/0332G01N21/6428G01N21/76G01N21/763G01N2021/6419G01N2021/6421G01N2021/6441G01N2201/0221G01N2201/0625G01N2201/0627G01N2201/0693
    • A detection system is provided, the detection system comprising a light source that generates excitation light having a wavelength sufficient to excite a fluorophore in a sample; an excitation filter positioned along a first line along a path of the excitation light, the excitation filter transmitting the excitation light from the light source; a beam splitter positioned along the first line, the beam splitter reflecting the excitation light transmitted by the excitation filter along a second line toward a mirror positioned on one side of the beam splitter, and passing emitted light reflected along the second line; the mirror, positioned to reflect the excitation light from the beam splitter to the fluorophore in the sample along a third line, normal to both the first and second lines, wherein the mirror further reflects emitted light emitted along the third line, along the second line toward the beam splitter; an emission filter positioned along the second line, on a second side of the beam splitter; and a detector that detects the emitted light transmitted by the emission filter.
    • 提供一种检测系统,所述检测系统包括产生具有足以激发样品中的荧光团的波长的激发光的光源; 激励滤光器,其沿着激励光的路径沿着第一线定位,所述激发滤光器透射来自所述光源的激发光; 分束器,沿着第一线定位,分束器将由激励滤光器透射的激发光沿着第二线反射到位于分束器一侧的反射镜,并且使沿着第二线反射的发射光反射; 所述反射镜被定位成将来自分束器的激发光沿着与第一和第二线垂直的第三线反射到样品中的荧光团,其中反射镜还沿着第二条线反射沿着第三条线发射的发射光 朝向分束器; 沿着所述第二线定位在所述分束器的第二侧上的发射滤光器; 以及检测由发射滤波器发射的发射光的检测器。
    • 9. 发明申请
    • SYSTEM AND METHOD FOR AMPLIFYING A NUCLEIC ACID MOLECULE
    • 用于放大核酸分子的系统和方法
    • US20090263870A1
    • 2009-10-22
    • US12428901
    • 2009-04-23
    • Juergen PipperPavel NeuzilYi ZhangMuhammad Khidhir KhairudinTseng-Ming Hsieh
    • Juergen PipperPavel NeuzilYi ZhangMuhammad Khidhir KhairudinTseng-Ming Hsieh
    • C12P19/34C12M1/00
    • C12P19/34C12Q1/686C12Q2527/125C12Q2563/137
    • There is provided a method and/or system which allow on-chip preconditioning of complex real-world samples and/or handling of limited amounts of target material, and/or on-chip nucleic acid amplification process, using a free droplet containing magnetic attractable material. The nucleic acid amplification process comprises controlling the position of the magnetic attractable material and performing the nucleic acid amplification in a thermocycling droplet located onto at least one temperature zone. The low thermal masses of the herein described heaters/temperature sensors come along with fast temperature transitions within the corresponding temperature zones allowing impressing temperature gradients in at least one temperature zone between subsequent or within the same thermocycle(s). Additionally, the variable residence times of the droplet in a given temperature zone permit to customize the denaturation, annealing and/or extension times within the same or between different PCR runs. Additionally, the herein described method and/or system allow amplification of one or more nucleic acid molecules. Additionally, the herein described method and/or system allow real-time monitoring with or without the presence of magnetic attractable material bound to said nucleic acid molecule.
    • 提供了一种方法和/或系统,其允许使用包含磁性可吸引的自由液滴来对复杂的现实世界样品进行片上预处理和/或处理有限量的靶材料和/或片上核酸扩增过程 材料。 核酸扩增方法包括控制磁性可吸引材料的位置并在位于至少一个温度区域上的热循环液滴中进行核酸扩增。 本文描述的加热器/温度传感器的低热质量伴随着相应温度区域内的快速温度转变,允许在相同或相同的热循环之间的至少一个温度区域内施加温度梯度。 此外,液滴在给定温度区域的可变停留时间允许在相同或不同PCR运行之间定制变性,退火和/或延伸时间。 另外,本文所述的方法和/或系统允许扩增一个或多个核酸分子。 另外,本文描述的方法和/或系统允许使用或不存在与所述核酸分子结合的可磁性吸引材料的实时监测。