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    • 9. 发明申请
    • APPARATUS, SYSTEM AND METHODS FOR COMPARING DRUG SAFETY USING HOLISTIC ANALYSIS AND VISUALIZATION OF PHARMACOLOGICAL DATA
    • 用于比较药物安全性的装置,系统和方法,使用HOLISTIC ANALYSIS和可视化的药理学数据
    • US20120078840A1
    • 2012-03-29
    • US13096063
    • 2011-04-28
    • Gopal AvinashAnanth MohanZhongmin LinRick Wascher
    • Gopal AvinashAnanth MohanZhongmin LinRick Wascher
    • G06N5/02
    • G16H50/70
    • Certain examples provide systems and methods for holistic viewing to provide comparative analysis and decision support in a drug development process, and safety testing. An example method includes providing a first set of data corresponding to a drug of interest; providing a reference set of drug interaction data, comparing the first set of data to the reference set using a holistic analysis, and reporting the results of the comparison. An example of the holistic analysis and viewing apparatus for drug safety comprises a standardizer to at least one of standardize and normalize drug interaction data related to drug safety; a deviation analyzer to compare the drug interaction data to data corresponding to a drug under review using a holistic analysis, and a reporter for reporting the output of the deviation analyzer.
    • 某些实例提供了整体观察的系统和方法,以便在药物开发过程和安全性测试中提供比较分析和决策支持。 示例性方法包括提供与感兴趣的药物相对应的第一组数据; 提供一组药物相互作用数据,使用整体分析将第一组数据与参考集进行比较,并报告比较结果。 用于药物安全的整体分析和观察装置的一个例子包括标准化器,至少标准化和规范与药物安全有关的药物相互作用数据; 偏差分析仪,用于使用整体分析将药物相互作用数据与正在审查的药物相对应的数据进行比较,以及用于报告偏差分析仪的输出的报告人。
    • 10. 发明申请
    • APPARATUS, SYSTEM AND METHODS FOR ASSESSING DRUG EFFICACY USING HOLISTIC ANALYSIS AND VISUALIZATION OF PHARMACOLOGICAL DATA
    • 用于评估药物分析和药物数据可视化的药物效果的装置,系统和方法
    • US20120078521A1
    • 2012-03-29
    • US13096046
    • 2011-04-28
    • Gopal AvinashAnanth MohanZhongmin LinRick Wascher
    • Gopal AvinashAnanth MohanZhongmin LinRick Wascher
    • G06F19/00
    • G01N33/15G06F19/3456G16C20/50G16C20/70G16C20/80G16H50/70
    • Certain examples provide systems and methods for holistic viewing to provide comparative analysis and decision support in a drug development process. An example method includes a computer-implemented method for assessing drug efficacy, comprising: accessing a first data set related to the performance of a target drug for a given indication; accessing a second data set related to a control for the indication; comparing the data for the target drug and the data for the control on at least one of a plurality of different metrics using a holistic analysis, wherein the at least one metric corresponds to an outcome associated with the indication and generating a corresponding report. An example apparatus/system includes a holistic analysis and viewing system to support the assessment of drug efficacy, said system comprising: a standardizer to at least one of standardize and normalize data related to drug development; a deviation analyzer to analyze said data based on at least one of a plurality of different efficacy metrics, wherein a quantified variation between a first data set of results corresponding to an identified target drug and a second data set of results corresponding to a control, wherein said first data set of results is provided for comparison with the second data set of results and the deviation therebetween is compared to the at least one efficacy metric.
    • 某些例子提供了整体观察的系统和方法,以在药物开发过程中提供比较分析和决策支持。 示例性方法包括用于评估药物功效的计算机实现的方法,包括:访问与给定指示的目标药物的性能相关的第一数据集; 访问与所述指示的控制相关的第二数据集; 使用整体分析来比较目标药物的数据和用于多个不同度量中的至少一个的用于控制的数据,其中所述至少一个度量对应于与所述指示相关联的结果并生成相应的报告。 示例性装置/系统包括支持药物功效评估的整体分析和观察系统,所述系统包括:标准化器,其至少一个标准化和归一化与药物开发有关的数据; 偏差分析器,用于基于多个不同功效度量中的至少一个来分析所述数据,其中对应于所识别的目标药物的第一结果数据集与对照于对照的结果的第二数据集之间的量化变化,其中 提供所述第一数据结果数据集用于与第二数据结果集进行比较,并且将它们之间的偏差与至少一个功效度量进行比较。