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    • 5. 发明授权
    • Fungicidally active compounds
    • 杀真菌活性化合物
    • US5672492A
    • 1997-09-30
    • US427015
    • 1995-04-24
    • Ruby Illum NielsenFrank Winther Rasmussen
    • Ruby Illum NielsenFrank Winther Rasmussen
    • A01N43/16A61K31/352C07D311/86C12P17/16C12P17/06C12N1/14
    • A01N43/16A61K31/352C07D311/86C12P17/162C12R1/645Y10S435/911
    • Novel compounds of formula I ##STR1## wherein R.sup.1 is independently hydrogen, hydroxy, alkyl with 1 to 6 carbon atoms, acyloxy groups with 1 to 6 carbon atoms, alkyloxy with 1 to 6 carbon atoms or from 1 to 5 sugar moieties; and R.sup.2 is independently hydrogen, or alkyl with 1 to 6 carbon atoms. The compounds are producible by aerobic cultivation on suitable nutrient media under suitable conditions of a strain of the fungus Ascochyta sp., subsequent recovery of the active component from the fermentation medium, and optionally modifying the active compound to obtain a compound of the desired formula I. Disclosed is also microorganisms capable of producing said compounds, compositions containing said compounds, and the use of such compositions for controlling fungi in valuable crops, animals, including birds and mammals, and in the preservation of wood, paints and edible products.
    • 式I的新型化合物其中R 1独立地是氢,羟基,具有1至6个碳原子的烷基,具有1至6个碳原子的酰氧基,1至6个碳原子的烷氧基或1至5个糖部分 ; 并且R 2独立地是氢或具有1至6个碳原子的烷基。 这些化合物可以通过在合适的营养培养基上在真菌Ascochyta sp。菌株的合适条件下进行需氧培养来生产,随后从发酵培养基中回收活性成分,并任选地改性活性化合物以获得所需式I化合物 还公开了能够产生所述化合物的微生物,含有所述化合物的组合物,以及这些组合物用于控制有价值作物,动物,包括鸟类和哺乳动物中的真菌以及保护木材,油漆和可食用产品的用途。