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1. 发明授权

US06312099B1 Printing uniformity using printhead segments in pagewidth digital printers 失效
标题翻译：使用页宽数字打印机中的打印头片段进行打印均匀性
公开(公告)号：US06312099B1
公开(公告)日：2001-11-06
申请号：US08784668
申请日：1997-01-21
申请人： Gilbert A. Hawkins , Xin Wen , William Y. Fowlkes
发明人： Gilbert A. Hawkins , Xin Wen , William Y. Fowlkes
IPC分类号： B41J2155
CPC分类号： B41J2/14112 , B41J2/04505 , B41J2/04528 , B41J2/0458 , B41J2/04581 , B41J2/14032 , B41J2/14209 , B41J2/155 , B41J2002/14475
摘要： A binary pagewidth printhead without substantial grayscale capability includes an array of adjacent printhead segments that are distributed across the pagewidth printhead so that adjacent segments overlap at their ends by a predetermined distance. A plurality of printing pixels extending along each segment have physical differences that effect substantially non-uniform transfer functions that decrease toward the ends of segments over the overlap distance. The physical characteristics of the printing pixels are such the their transfer functions vary linearly over the overlap distance. The physical characteristics of the printing pixels may be such the their transfer functions increase monotonically from a small value at the ends of the printhead segments to a larger value away from the ends of the printhead segments. The physical characteristics of the printing pixels in a central portion of each segment are preferably uniform such the their transfer functions are constant over the central portions. Preferably, the transfer functions applied to adjacent segments are of mirror symmetry.
摘要翻译：不具有实质灰度能力的二进制页宽打印头包括分布在页宽打印头上的相邻打印头段的阵列，使得相邻的片段在其端部与预定距离重叠。沿着每个段延伸的多个印刷像素具有实质上不均匀的传递函数的物理差异，这些传递函数在重叠距离上朝向段的端部减小。打印像素的物理特性就是它们的传递函数在重叠距离上线性变化。打印像素的物理特性可能是这样的，它们的传递函数从打印头片段端部的较小值单调增加到远离打印头片段端部的较大值。每个段的中心部分中的印刷像素的物理特性优选是均匀的，使得它们的传递函数在中心部分上是恒定的。优选地，施加到相邻段的传递函数是镜像对称的。

2. 发明授权

US06238584B1 Method of forming ink jet nozzle plates 有权
标题翻译：形成喷墨喷嘴板的方法
公开(公告)号：US06238584B1
公开(公告)日：2001-05-29
申请号：US09257895
申请日：1999-03-02
申请人： Gilbert A. Hawkins , Xin Wen
发明人： Gilbert A. Hawkins , Xin Wen
IPC分类号： G11B5127
CPC分类号： B41J2/1642 , B41J2/162 , B41J2/1623 , B41J2/1628 , B41J2/1629 , B41J2/1631 , B41J2/1632 , B41J2/1646 , Y10T29/49346
摘要： A method for forming an ink jet nozzle plate includes providing a structure having a top substrate layer, a bottom substrate layer, and a buried layer disposed between the top substrate layer and the bottom substrate layer; selectively etching the top substrate layer to form a plurality of spaced ink cavities in the top substrate layer exposing portions of the buried layer; removing by etching the bottom substrate layer and bonding a base having ink delivery channels over the top substrate layer, with at least one channel corresponding to each ink cavity to thereby form the ink jet nozzle plate; and providing a mask having a plurality of openings over the buried layer and etching through such mask openings through the buried layer to the ink cavities to provide at least one bore region corresponding to each ink cavity to provide ink ejection access to such ink cavities so that the buried layer has portions which overhang the ink cavity.
摘要翻译：一种形成喷墨喷嘴板的方法包括提供一种具有顶部基底层，底部基底层和设置在顶部基底层和底部基底层之间的掩埋层的结构; 选择性地蚀刻顶部衬底层以在顶部衬底层中形成暴露部分埋层的多个间隔开的油墨腔; 通过蚀刻底部基底层并将具有墨水输送通道的基底结合在顶部基底层上，通过与每个墨水腔对应的至少一个通道从而形成喷墨喷嘴板; 以及提供掩模，其在所述掩埋层上方具有多个开口，并且通过所述掩模开孔蚀刻穿过所述掩埋层到所述墨腔，以提供对应于每个墨腔的至少一个孔区域，以提供对所述墨腔的墨喷射通路，使得掩埋层具有伸出墨腔的部分。

3. 发明授权

US06303042B1 Making ink jet nozzle plates 有权
标题翻译：制作喷墨喷嘴板
公开(公告)号：US06303042B1
公开(公告)日：2001-10-16
申请号：US09260698
申请日：1999-03-02
申请人： Gilbert A. Hawkins , Xin Wen
发明人： Gilbert A. Hawkins , Xin Wen
IPC分类号： G11B5127
CPC分类号： B41J2/1628 , B41J2/162 , B41J2/1623 , B41J2/1629 , B41J2/1631 , B41J2/1632 , B41J2/1642 , B41J2/1645 , B41J2/1646
摘要： A method for forming an ink jet nozzle plate includes providing a structure having a top substrate layer, a bottom substrate layer, and a buried layer disposed between the top substrate layer and the bottom substrate layer; providing a composite mask over the top substrate layer having a cavity mask which provides openings and a bore mask having openings which are entirely within the openings of the cavity mask and extend to the top substrate layer; anisotopically etching through the bore mask openings through top substrate layer and the buried layer into a portion of the bottom substrate layer; removing the bore mask and etching the top and bottom substrate layers without substantially affecting the buried layer to extend the openings in the top substrate layer and the bottom substrate layer; removing the cavity mask and attaching the top substrate layer to a base provided with ink delivery channels with correspond to the openings in the buried layer; and removing the bottom substrate layer.
摘要翻译：一种形成喷墨喷嘴板的方法包括提供一种具有顶部基底层，底部基底层和设置在顶部基底层和底部基底层之间的掩埋层的结构; 在具有提供开口的空腔掩模和具有开口的孔掩模的顶部衬底层上提供复合掩模，所述孔掩模完全位于腔掩模的开口内并延伸到顶部衬底层; 通过孔掩模开口各向异性地蚀刻通过顶部衬底层和掩埋层进入底部衬底层的一部分; 去除孔掩模并蚀刻顶部和底部衬底层，而基本上不影响掩埋层以延伸顶部衬底层和底部衬底层中的开口; 去除腔体掩模并将顶部基底层附接到具有与掩埋层中的开口相对应的具有墨水输送通道的底座; 并移除底部基底层。

4. 发明授权

US6154254A Electronic camera for producing a digital image having a multimode microfluidic printing device 失效
标题翻译：用于生产具有多模微流体打印装置的数字图像的电子照相机
公开(公告)号：US6154254A
公开(公告)日：2000-11-28
申请号：US950703
申请日：1997-10-15
申请人： Gilbert A. Hawkins , Xin Wen , Dale F. McIntyre
发明人： Gilbert A. Hawkins , Xin Wen , Dale F. McIntyre
IPC分类号： B41J3/42 , B41J3/44 , H04N1/00 , H04N1/195 , H04N1/21 , H04N5/225
CPC分类号： B41J3/445 , H04N1/00278 , H04N1/02805 , H04N1/195 , H04N1/2112 , H04N1/2154
摘要： An electronic camera for producing a digital image and a multimode microfluidic printing device for printing such digital image including a parallel associative interface structure having an image sensor in the camera for producing digital images and a microfluidic printing device including a plurality of colored ink reservoirs including several reservoirs for containing different colorants and a plurality of colorant delivery chambers. Circuitry responds to digital image produced by the sensor for image processing the digital image produced by the image sensor for controlling the microfluidic printing device to deliver colorants from the delivery chambers to an image transfer position. An image receiving medium is delivered to such medium to produce a visual image of the digital image.
摘要翻译：一种用于产生数字图像的电子照相机和用于打印这样的数字图像的多模微流体打印装置，所述数字图像包括在照相机中具有用于产生数字图像的图像传感器的平行相关界面结构，以及包括多个彩色墨水容器的微流体打印装置，用于容纳不同着色剂的储存器和多个着色剂输送室。电路响应由传感器产生的数字图像，用于图像处理由图像传感器产生的数字图像，用于控制微流体打印装置将着色剂从输送室输送到图像转印位置。图像接收介质被传送到这样的介质以产生数字图像的视觉图像。

5. 发明授权

US06258286B1 Making ink jet nozzle plates using bore liners 失效
标题翻译：使用内衬制造喷墨喷嘴板
公开(公告)号：US06258286B1
公开(公告)日：2001-07-10
申请号：US09260248
申请日：1999-03-02
申请人： Gilbert A. Hawkins , Xin Wen
发明人： Gilbert A. Hawkins , Xin Wen
IPC分类号： G11B5127
CPC分类号： B41J2/1628 , B41J2/162 , B41J2/1623 , B41J2/1629 , B41J2/1631 , B41J2/1632 , B41J2/1642 , B41J2/1645 , B41J2/1646
摘要： A method for forming an ink jet nozzle plate includes providing a structure having a top substrate layer, a bottom substrate layer, and a buried layer disposed between the top substrate layer and the bottom substrate layer; providing a patterned bore mask having openings which extend to the top substrate layer; anisotropically etching through the openings through the top substrate layer, the buried layer, and into a portion of the bottom substrate layer; providing a bore liner into the openings formed through the top substrate layer, the buried layer, and into the etched portion of the bottom substrate layer; removing the bore mask and providing a cavity mask having openings aligned with the bore liners; anisotropically etching the top substrate layer to expose the bore liners; and removing the cavity mask and providing an ink jet nozzle plate layer over the top substrate layer and extending to be in contact with the bore liners to form bore regions in the ink jet nozzle plate layer; attaching the ink jet nozzle plate layer to a base having ink delivery channels which correspond to the bore regions; and removing the bottom substrate layer.
摘要翻译：一种形成喷墨喷嘴板的方法包括提供一种具有顶部基底层，底部基底层和设置在顶部基底层和底部基底层之间的掩埋层的结构; 提供具有延伸到顶部基底层的开口的图案化孔罩; 通过顶部各向异性蚀刻穿过顶部基底层，掩埋层，并进入底部基底层的一部分; 在通过顶部基底层，掩埋层形成的开口中和在底部基底层的蚀刻部分中提供孔衬垫; 移除所述孔罩并提供具有与所述孔衬套对准的孔的腔罩; 各向异性地蚀刻顶部基底层以暴露孔内衬; 并且移除所述腔罩并在所述顶部基底层上方提供喷墨喷嘴板层并且延伸成与所述孔衬套接触以在所述喷墨喷嘴板层中形成孔区域; 将喷墨喷嘴板层附接到具有对应于孔区域的油墨输送通道的基部; 并移除底部基底层。

6. 发明授权

US06214245B1 Forming-ink jet nozzle plate layer on a base 有权
标题翻译：底座上的成型喷墨喷嘴板层
公开(公告)号：US06214245B1
公开(公告)日：2001-04-10
申请号：US09260303
申请日：1999-03-02
申请人： Gilbert A. Hawkins , Xin Wen
发明人： Gilbert A. Hawkins , Xin Wen
IPC分类号： G11B5127
CPC分类号： B41J2/1628 , B41J2/162 , B41J2/1623 , B41J2/1629 , B41J2/1631 , B41J2/1632 , B41J2/1642 , B41J2/1645 , B41J2/1646
摘要： A method for forming an ink jet nozzle plate includes providing a buried layer over a bottom substrate layer; providing and patterning a top substrate layer over the buried layer and having openings having inclined walls; providing an ink jet nozzle plate layer over the patterned top substrate layer and into the openings formed in the patterned top substrate layer, the ink jet nozzle plate layer contacting the buried layer; attaching the ink jet nozzle plate layer to a base having ink delivery channels; removing by etching the bottom substrate layer; and providing bore regions into the ink jet nozzle plate layer with each bore region corresponding to a delivery channel.
摘要翻译：一种用于形成喷墨喷嘴板的方法包括在底部基底层上设置掩埋层; 提供和图案化掩埋层上的顶部衬底层并具有具有倾斜壁的开口; 在图案化的顶部基底层上方形成喷墨喷嘴板层，并且形成在图案化的顶部基底层中形成的开口中，喷墨喷嘴板层与掩埋层接触; 将喷墨喷嘴板层附接到具有油墨输送通道的底座上; 通过蚀刻底部基底层去除; 以及将每个孔区域对应于输送通道的孔区域提供到喷墨喷嘴板层中。

7. 发明授权

US06214192B1 Fabricating ink jet nozzle plate 失效
标题翻译：制造喷墨喷嘴板
公开(公告)号：US06214192B1
公开(公告)日：2001-04-10
申请号：US09208358
申请日：1998-12-10
申请人： Gilbert A. Hawkins , Xin Wen
发明人： Gilbert A. Hawkins , Xin Wen
IPC分类号： C25D110
CPC分类号： B41J2/1632 , B41J2/1433 , B41J2/162 , B41J2/1628 , B41J2/1629 , B41J2/1631 , B41J2/1637 , C25D1/08 , C25D1/10
摘要： A method for forming an ink jet nozzle plate with ink jet nozzles, including providing a first mold formed with spaced-apart recesses; providing inlay material in the spaced-apart recesses; attaching a base to the inlay material; separating the first mold from the inlay material and the base, thereby forming a final mold having a plurality of inlay material protrusions over the base, the protrusions and base defining the shape and the size of the ink jet nozzles; providing plate forming material between the protrusions and over the base in the final mold; and releasing the plate forming material to form an ink jet nozzle plate having a plurality of ink jet nozzles.
摘要翻译：一种用于形成具有喷墨嘴的喷墨喷嘴板的方法，包括提供形成有间隔开的凹部的第一模具; 在间隔开的凹槽中提供镶嵌材料; 将基底附接到嵌体材料; 将第一模具与嵌体材料和基底分离，从而形成在基底上具有多个嵌入材料突起的最终模具，突出部和基部限定喷墨嘴的形状和尺寸; 在所述突起之间提供板形成材料，并在所述最终模具中提供在所述基底上; 并释放板形成材料以形成具有多个喷墨嘴的喷墨喷嘴板。

8. 发明授权

US11110176B2 Composition and method for the protection of proteins, cell components and cells during temperature stress 有权
公开(公告)号：US11110176B2
公开(公告)日：2021-09-07
申请号：US15821671
申请日：2017-11-22
申请人： Xin Wen
发明人： Xin Wen
IPC分类号： A61K47/42 , C12N9/96 , C12N1/04 , A01N1/02 , A61K38/28
摘要： Embodiments of the disclosure pertain to compositions containing (i) one or more non-antifreeze proteins or cell components or cells and (ii) one or more antifreeze proteins (AFPs), mimetics thereof, and/or analogs thereof, and a method of stabilizing a biologic (e.g., a protein, microbe, cell component or cell) against temperature stress and aggregation. The AFP may be selected from known antifreeze polypeptides and antifreeze peptides, analogs and mimetics of antifreeze proteins, active fragments of such antifreeze proteins, polypeptide and peptide mimetics, antifreeze peptoids and polymers, and combinations thereof. The non-antifreeze protein, cell component or cell comprises a known protein, cell component or cell used in the pharmaceutical, medical, agricultural, veterinary and/or food industry(ies). The AFP protects the function of the non-antifreeze protein, microbe(s), cell component(s) or cell(s) under temperature stress (e.g., a temperature of −20-60° C.).

9. 发明授权

US08082053B2 Automated manufacturing system 有权
标题翻译：自动化制造系统
公开(公告)号：US08082053B2
公开(公告)日：2011-12-20
申请号：US11935320
申请日：2007-11-05
申请人： Xin Wen , Russ Ennio Muzzolini , Jeff D. Boone
发明人： Xin Wen , Russ Ennio Muzzolini , Jeff D. Boone
IPC分类号： G06F19/00
CPC分类号： G05B19/41865 , G05B2219/25182 , G05B2219/32263 , G06Q10/06 , Y02P90/20
摘要： An automated manufacturing system comprises a computer processing system and a plurality of consolidation systems. The computer processing system receives information on product subbatches and product packages and consolidation status information to produce consolidation assignment information, each product package comprising one or more product subbatches. The consolidation systems receive the product subbatches in accordance to the consolidation assignment information and consolidate the product subbatches into product packages, wherein the status of the consolidation systems are tracked and the consolidation status information is sent to the computer processing system.
摘要翻译：自动化制造系统包括计算机处理系统和多个合并系统。计算机处理系统接收关于产品子批和产品包和合并状态信息的信息以产生合并分配信息，每个产品包包括一个或多个产品子批。整合系统根据合并分配信息接收产品子批次，并将产品子批次合并到产品包中，其中跟踪合并系统的状态，并将合并状态信息发送到计算机处理系统。

10. 发明申请

US20100331369A1 Therapeutic Agents Useful for Treating Pain 有权
标题翻译：用于治疗疼痛的治疗剂
公开(公告)号：US20100331369A1
公开(公告)日：2010-12-30
申请号：US12817773
申请日：2010-06-17
申请人： Qun Sun , Xin Wen
发明人： Qun Sun , Xin Wen
IPC分类号： A61K31/444 , A61P29/00
CPC分类号： A61K31/444 , C07D401/04 , C07D401/14 , C07D413/14 , C07D417/04 , C07D417/14
摘要： A compound of formula: where Ar1, Ar2, X, R3, and m are as disclosed herein or a pharmaceutically acceptable salt thereof (a “Cycloheteroalkenyl Compound”); compositions comprising an effective amount of a Cycloheteroalkenyl Compound; and methods for treating or preventing pain, UI, an ulcer, IBD, IBS, an addictive disorder, Parkinson's disease, parkinsonism, anxiety, epilepsy, stroke, a seizure, a pruritic condition, psychosis, a cognitive disorder, a memory deficit, restricted brain function, Huntington's chorea, amyotrophic lateral sclerosis, dementia, retinopathy, a muscle spasm, a migraine, vomiting, dyskinesia, or depression in an animal comprising administering to an animal in need thereof an effective amount of a Cycloheteroalkenyl Compound are disclosed herein.
摘要翻译：式中的化合物：其中Ar1，Ar2，X，R3和m如本文所公开或其药学上可接受的盐（“环烯基烯基化合物”）; 包含有效量的环烯基烯基化合物的组合物; 以及用于治疗或预防疼痛，UI，溃疡，IBD，IBS，成瘾性障碍，帕金森病，帕金森综合征，焦虑，癫痫，中风，癫痫发作，瘙痒症状，精神病，认知障碍，记忆缺陷，受限制脑功能，亨廷顿舞蹈病，肌萎缩性侧索硬化，痴呆，视网膜病变，肌肉痉挛，偏头痛，呕吐，运动障碍或抑郁症，包括向有需要的动物施用有效量的环烯基烯基化合物。

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