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1. 发明申请

US20090181905A1 CRYSTALLINE FORM OF 1' -(1-METHYLETHYL)-4' -[(2-FLUORO-4-METHOXYPHENYL)METHYL]-5' -METHYL-1H-PYRAZOL-3' -O-BETA-D-GLUCOPYRANOSIDE, A METHOD FOR ITS PREPARATION AND THE USE THEREOF FOR PREPARING MEDICAMENTS 失效
标题翻译： 1' - （1-甲基乙基）-4' - [（2-氟-4-甲氧基苯基）甲基] -5'-甲基-1H-吡唑-3'-O- BETA-D-吡喃葡萄糖苷的晶体形式，方法由于其制备及其用于制备药物的用途
公开(公告)号：US20090181905A1
公开(公告)日：2009-07-16
申请号：US12404442
申请日：2009-03-16
申请人： Gerd KRAEMER , Hans-Juergen MARTIN , Gebhard ADELGOSS , Klaus DUGI , Adil DURAN , Peter EICKELMANN , Steffen MAIER , Sabine PINNETTI , Regine RITTER , Gebhard SCHILCHER , Ruediger STREICHER , Leo THOMAS
发明人： Gerd KRAEMER , Hans-Juergen MARTIN , Gebhard ADELGOSS , Klaus DUGI , Adil DURAN , Peter EICKELMANN , Steffen MAIER , Sabine PINNETTI , Regine RITTER , Gebhard SCHILCHER , Ruediger STREICHER , Leo THOMAS
IPC分类号： A61K31/7052 , C07H17/02 , A61P3/00
CPC分类号： C07H17/02
摘要： The invention relates to a crystalline form of 1′-(1-methylethyl)-4′-[(2-fluoro-4-methoxyphenyl)methyl]-5′-methyl-1H-pyrazol-3′-O-β-D-glucopyranoside, to a method for the preparation thereof, as well as to the use thereof for preparing medicaments.
摘要翻译：本发明涉及1' - （1-甲基乙基）-4' - [（2-氟-4-甲氧基苯基）甲基] -5'-甲基-1H-吡唑-3'-O-β-D - 吡喃葡萄糖苷，其制备方法，以及其用于制备药物的用途。

2. 发明申请

US20130079518A1 REGIOSELECTIVE PREPARATION OF SUBSTITUTED PYRIMIDINES 审中-公开
标题翻译：取代的吡咯烷酮的选择性制备
公开(公告)号：US20130079518A1
公开(公告)日：2013-03-28
申请号：US13678658
申请日：2012-11-16
申请人： Guenter LINZ , Gerd KRAEMER , Adil DURAN
发明人： Guenter LINZ , Gerd KRAEMER , Adil DURAN
IPC分类号： C07D239/47 , C07D403/12 , C07D239/52
CPC分类号： C07D239/47 , C07D239/42 , C07D239/52 , C07D403/12
摘要： The present invention relates to a method of making pyrimidines of formula (III) wherein X1, X2, R1 and R2 have the meanings as defined herein.
摘要翻译：本发明涉及制备式（III）的嘧啶的方法，其中X 1，X 2，R 1和R 2具有如本文所定义的含义。

3. 发明申请

US20140213787A1 REGIOSELECTIVE PREPARATION OF 2-AMINO-5-TRIFLUOROMETHYLPYRIMIDINE DERIVATIVES 审中-公开
标题翻译： 2-氨基-5-三氟甲基嘧啶衍生物的选择性制备
公开(公告)号：US20140213787A1
公开(公告)日：2014-07-31
申请号：US14244351
申请日：2014-04-03
申请人： Guenter LINZ , Gerd KRAEMER
发明人： Guenter LINZ , Gerd KRAEMER
IPC分类号： C07D239/47
CPC分类号： C07D239/47 , C07D239/34 , C07D239/48
摘要： The present invention relates to a method of making 2,4-differentiated 5-trifluoromethylpyrimidines, which are useful as intermediates in the manufacture of active pharmaceutical substances.
摘要翻译：本发明涉及制备2,4-分化的5-三氟甲基嘧啶的方法，其可用作制备活性药物物质的中间体。

4. 发明申请

US20110190499A1 SELECTIVE SYNTHESIS OF FUNCTIONALIZED PYRIMIDINES 有权
标题翻译：官能化吡咯烷酮的选择性合成
公开(公告)号：US20110190499A1
公开(公告)日：2011-08-04
申请号：US12853732
申请日：2010-08-10
申请人： Guenter LINZ , Gerd KRAEMER , Sabrina KUSSEROW , Juergen SCHNAUBELT
发明人： Guenter LINZ , Gerd KRAEMER , Sabrina KUSSEROW , Juergen SCHNAUBELT
IPC分类号： C07D239/02
CPC分类号： C07D239/47 , C07D239/34 , C07D401/12
摘要： The present invention relates to a process for making 2,4-differentiated 5-trifluoromethyl pyrimidines and 2-amino-5-trifluoromethyl-pyrimidine derivatives, which compounds are useful in the preparation of pharmacologically active compounds.
摘要翻译：本发明涉及制备2,4-分化的5-三氟甲基嘧啶和2-氨基-5-三氟甲基 - 嘧啶衍生物的方法，该化合物可用于制备药理活性化合物。

5. 发明申请

US20080134668A1 Method for Monitoring the Functionality of the Heating of a Catalytic Converter Situated in an Exhaust System of an Internal Combustion Engine 有权
标题翻译：用于监测位于内燃机排气系统中的催化转化器加热功能的方法
公开(公告)号：US20080134668A1
公开(公告)日：2008-06-12
申请号：US12033568
申请日：2008-02-19
申请人： Gerd KRAEMER , Stefan Uhl , Wolf Kiefer , Gerhard Schulz
发明人： Gerd KRAEMER , Stefan Uhl , Wolf Kiefer , Gerhard Schulz
IPC分类号： F01N3/00
CPC分类号： F02D41/0245 , F02D35/028 , F02D41/0255 , F02D41/22 , F02D2041/1433 , F02D2200/1004 , F02D2250/18 , F02D2250/22 , F02P5/145 , Y02T10/26 , Y02T10/46
摘要： The diagnosis of the heating of a catalytic converter situated in an exhaust system of an internal combustion engine is described. The system includes monitoring the actual ignition angle intervention. A current ignition angle is acquired over a specified time and converted into a torque model used for catalytic converter heating. Using the torque model, a degree of fulfillment of executed catalytic converter heating measures is obtained and an error signal is generated by comparing the obtained degree of fulfillment to a limiting value.
摘要翻译：描述了位于内燃机的排气系统中的催化转化器的加热的诊断。该系统包括监测实际点火角干预。在指定时间内获取当前点火角，并转换为用于催化转化器加热的转矩模型。使用扭矩模型，获得执行的催化转化器加热措施的程度，并通过将获得的履行程度与限制值进行比较来产生误差信号。

6. 发明申请

US20080242504A1 Shifting Point Display in a Motor Vehicle Having a Manual Transmission 有权
标题翻译：具有手动变速器的机动车辆中的换档点显示
公开(公告)号：US20080242504A1
公开(公告)日：2008-10-02
申请号：US12137055
申请日：2008-06-11
申请人： Gerd KRAEMER , Alberto Croci
发明人： Gerd KRAEMER , Alberto Croci
IPC分类号： F16H63/42 , F16H59/70
CPC分类号： F16H63/42 , F16H61/0213 , F16H2063/426 , Y10T477/692
摘要： A shifting point display for indicating shift advice is provided in a motor vehicle having a manual transmission and a control unit for the continuous determination of a current operating point of the motor vehicle. At least one characteristic upshift indication curve or a characteristic downshift indication curve is stored in an electronic memory. An upshift indication or a downshift indication is displayed when the characteristic upshift indication curve or the characteristic downshift indication curve is reached by the current operating point and a currently differently engaged gear. The upshift indication or the downshift indication is indicated until the driver has carried out a corresponding upshift operation or downshift operation or until the current operating point has reached and/or fallen below a characteristic upshift indication hysteresis curve that is smaller than the characteristic upshift indication curve, or has reached and/or exceeded a characteristic downshift indication hysteresis curve that is greater than the characteristic downshift indication curve.
摘要翻译：在具有用于连续确定机动车辆的当前工作点的手动变速器和控制单元的机动车辆中提供用于指示换档通知的换档点显示。至少一个特征换高指示曲线或特征降档指示曲线存储在电子存储器中。当当前工作点和当前不同的啮合齿轮达到特征换高指示曲线或特征降档指示曲线时，显示升档指示或降档指示。指示升档指示或降档指示，直到驾驶员执行相应的升档操作或降档操作，或直到当前操作点达到和/或低于小于特征升档指示曲线的特征升档指示滞后曲线，或已经达到和/或超过了比特性降档指示曲线大的特征降档指示滞后曲线。

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