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1. 发明申请

US20110168575A1 SAMPLE CHARACTERIZATION BASED ON AC MEASUREMENT METHODS 审中-公开
标题翻译：基于交流测量方法的样本特征
公开(公告)号：US20110168575A1
公开(公告)日：2011-07-14
申请号：US12684277
申请日：2010-01-08
申请人： Georgeta Lica , Harvey B. Buck , Henning Groll
发明人： Georgeta Lica , Harvey B. Buck , Henning Groll
IPC分类号： G01N27/26
CPC分类号： G01N27/3274
摘要： One aspect concerns a technique for detecting analyte concentrations, such as glucose concentrations, in blood or other bodily fluids. This technique utilizes an electrochemical test strip that includes a mediator system that generates a linear faradic response at relatively low applied potential differences. An alternating current excitation signal is applied to blood in the test strip. The alternating current excitation signal includes a low frequency signal and a high frequency signal that has a higher frequency than the low frequency signal. The glucose concentration is determined by measuring a low frequency response to the low frequency signal, measuring a high frequency response to the high frequency signal, estimating the glucose concentration based on the low frequency response, and correcting the glucose concentration for one or more error-causing variables based on the high frequency response.
摘要翻译：一方面涉及用于检测血液或其他体液中的分析物浓度，例如葡萄糖浓度的技术。该技术利用电化学测试条，其包括在相对低的施加电位差下产生线性法拉第响应的介体系统。交流电激励信号被施加到测试条中的血液。交流励磁信号包括低频信号和具有比低频信号更高频率的高频信号。葡萄糖浓度通过测量对低频信号的低频响应，测量对高频信号的高频响应，基于低频响应估计葡萄糖浓度，以及校正一个或多个误差信号的葡萄糖浓度，导致基于高频响应的变量。

2. 发明授权

US08663442B2 System and method for analyte measurement using dose sufficiency electrodes 有权
标题翻译：使用剂量足够电极进行分析物测量的系统和方法
公开(公告)号：US08663442B2
公开(公告)日：2014-03-04
申请号：US12254515
申请日：2008-10-20
申请人： David W. Burke , Nigel A. Surridge , Henning Groll
发明人： David W. Burke , Nigel A. Surridge , Henning Groll
IPC分类号： G01N27/327
CPC分类号： G01N27/3274
摘要： A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the analyte is determined based upon the corrected DC response. Other methods and devices are disclosed.
摘要翻译：测量生物流体中的分析物的方法包括施加具有DC分量和AC分量的激发信号。测量AC和DC响应; 使用AC响应确定校正的DC响应; 并且基于校正的DC响应确定分析物的浓度。公开了其它方法和装置。

3. 发明授权

US07645421B2 System and method for coding information on a biosensor test strip 有权
标题翻译：用于在生物传感器测试条上编码信息的系统和方法
公开(公告)号：US07645421B2
公开(公告)日：2010-01-12
申请号：US10871403
申请日：2004-06-18
申请人： Henning Groll
发明人： Henning Groll
IPC分类号： G01N27/26 , G01N1/00
CPC分类号： G01N33/558 , G01N33/48771
摘要： The present invention provides a test strip for measuring a concentration of an analyte of interest in a biological fluid, wherein the test strip may be encoded with information that can be read by a test meter into which the test strip is inserted.
摘要翻译：本发明提供了一种用于测量生物流体中感兴趣的分析物的浓度的测试条，其中测试条可以由可以被测试条插入的测试仪读取的信息进行编码。

4. 发明授权

US07604721B2 System and method for coding information on a biosensor test strip 有权
标题翻译：用于在生物传感器测试条上编码信息的系统和方法
公开(公告)号：US07604721B2
公开(公告)日：2009-10-20
申请号：US10871489
申请日：2004-06-18
申请人： Henning Groll , Michael J. Celentano
发明人： Henning Groll , Michael J. Celentano
IPC分类号： C25B11/00 , G01N27/26
CPC分类号： G01N27/3272 , G01N33/48771
摘要： The present invention provides a test strip for measuring a concentration of an analyte of interest in a biological fluid, wherein the test strip may be encoded with information that can be read by a test meter into which the test strip is inserted.
摘要翻译：本发明提供了一种用于测量生物流体中感兴趣的分析物的浓度的测试条，其中测试条可以由可以被测试条插入的测试仪读取的信息进行编码。

5. 发明授权

US07476827B1 Method of making a biosensor 有权
标题翻译：制作生物传感器的方法
公开(公告)号：US07476827B1
公开(公告)日：2009-01-13
申请号：US10976740
申请日：2004-10-29
申请人： Raghbir S. Bhullar , Henning Groll , John T. Austera , Douglas P. Walling , Timothy L. Ranney , James L. Pauley, Jr.
发明人： Raghbir S. Bhullar , Henning Groll , John T. Austera , Douglas P. Walling , Timothy L. Ranney , James L. Pauley, Jr.
IPC分类号： B23K26/38
CPC分类号： G01N33/5438 , G01N27/3272 , G01N33/48771 , G01N2035/00811
摘要： The present invention relates to a method of forming a biosensor. The method includes providing a substrate coated with a electrically conductive material, ablating the electrically conductive material to form electrodes and a code pattern, wherein there is sufficient contrast between the conductive coating and the substrate such that the code pattern is discernible, and applying a reagent to at least one of the electrodes.
摘要翻译：本发明涉及形成生物传感器的方法。该方法包括提供涂覆有导电材料的基材，烧蚀导电材料以形成电极和编码图案，其中在导电涂层和基板之间存在足够的对比度，使得代码图案是可辨别的，并且施加试剂至少一个电极。

6. 发明申请

US20070249921A1 BIOLOGICAL TESTING SYSTEM 有权
标题翻译：生物测试系统
公开(公告)号：US20070249921A1
公开(公告)日：2007-10-25
申请号：US11612190
申请日：2006-12-18
申请人： Henning Groll , Michael Celentano , Joseph Finnerty
发明人： Henning Groll , Michael Celentano , Joseph Finnerty
IPC分类号： A61B5/05
CPC分类号： G01N27/3273
摘要： A connector for establishing electrical connection between a testing device and a test strip with a biological fluid thereon includes a contact pad on the test strip, and one or more contact wires in the testing device. When the strip is inserted into the testing device, part of the strip's end engages a contact portion of a contact wire and deflects it in a direction normal to the direction of insertion. In certain embodiments the radius of curvature (in the direction of insertion) of the contact portion is controlled to reduce abrasion of the strip by the wire. In other embodiments the radius of curvature (perpendicular to the direction of insertion) is controlled to reduce the abrasion of the strip by the wire. Sometimes the contact portion and/or contact pad is plated with a sacrificial material to reduce the coefficient of friction. In other embodiments various numbers of contacts receive the end of the strip substantially simultaneously, or are staggered in rows to distribute the resistance presented.
摘要翻译：用于在测试装置和测试条之间建立与生物流体之间的电连接的连接器包括测试条上的接触焊盘和测试装置中的一个或多个接触导线。当条带插入到测试装置中时，条带的一部分接合接触线的接触部分，并使其沿垂直于插入方向的方向偏转。在某些实施例中，接触部分的曲率半径（在插入方向上）被控制以减少带材的线的磨损。在其它实施例中，控制曲率半径（垂直于插入方向），以减少带材的磨损。有时，接触部分和/或接触垫被镀有牺牲材料以降低摩擦系数。在其他实施例中，各种数量的触点基本上同时接收条的端部，或者以行的方式交错以分布呈现的电阻。

7. 发明申请

US20050019945A1 System and method for coding information on a biosensor test strip 有权
公开(公告)号：US20050019945A1
公开(公告)日：2005-01-27
申请号：US10871599
申请日：2004-06-18
申请人： Henning Groll , Michael Celentano
发明人： Henning Groll , Michael Celentano
IPC分类号： G01N33/00
CPC分类号： G01N33/66 , G01N33/48771 , Y10T436/11 , Y10T436/25375
摘要： The present invention provides a test strip for measuring a concentration of an analyte of interest in a biological fluid, wherein the test strip may be encoded with information that can be read by a test meter into which the test strip is inserted.

8. 发明授权

US08507289B1 System and method for coding information on a biosensor test strip 有权
公开(公告)号：US08507289B1
公开(公告)日：2013-08-13
申请号：US13549757
申请日：2012-07-16
申请人： Henning Groll , Michael J. Celentano
发明人： Henning Groll , Michael J. Celentano
IPC分类号： G01N25/18
CPC分类号： G01N33/66 , G01N33/48771 , Y10T436/11 , Y10T436/25375
摘要： The present invention provides a test strip for measuring a concentration of an analyte of interest in a biological fluid, wherein the test strip may be encoded with information that can be read by a test meter into which the test strip is inserted.

9. 发明授权

US08206565B2 System and method for coding information on a biosensor test strip 有权
公开(公告)号：US08206565B2
公开(公告)日：2012-06-26
申请号：US10871986
申请日：2004-06-18
申请人： Henning Groll , Michael J. Celentano , Steven K. Moore
发明人： Henning Groll , Michael J. Celentano , Steven K. Moore
IPC分类号： C12M1/00
CPC分类号： G01N33/48771 , B01L3/5027 , B01L3/545
摘要： The present invention provides a test strip for measuring a concentration of an analyte of interest in a biological fluid, wherein the test strip may be encoded with information that can be read by a test meter into which the test strip is inserted.

10. 发明申请

US20120045845A1 SYSTEM AND METHOD FOR CODING INFORMATION ON A BIOSENSOR TEST STRIP 审中-公开
标题翻译：用于编码生物传感器测试条的信息的系统和方法
公开(公告)号：US20120045845A1
公开(公告)日：2012-02-23
申请号：US13285197
申请日：2011-10-31
申请人： Henning Groll , Michael J. Celentano
发明人： Henning Groll , Michael J. Celentano
IPC分类号： G01N25/08
CPC分类号： G01N33/66 , G01N33/48771 , Y10T436/11 , Y10T436/25375
摘要： The present invention provides a test strip for measuring a concentration of an analyte of interest in a biological fluid, wherein the test strip may be encoded with information that can be read by a test meter into which the test strip is inserted.
摘要翻译：本发明提供了一种用于测量生物流体中感兴趣的分析物的浓度的测试条，其中测试条可以由可以被测试条插入的测试仪读取的信息进行编码。

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