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1. 发明授权

US07276544B2 Process for manufacturing intraocular lenses with blue light absorption characteristics 有权
标题翻译：制造具有蓝光吸收特性的眼内透镜的方法
公开(公告)号：US07276544B2
公开(公告)日：2007-10-02
申请号：US10657356
申请日：2003-09-08
申请人： Yu-Chin Lai , Dominic V. Ruscio , George F. Green
发明人： Yu-Chin Lai , Dominic V. Ruscio , George F. Green
IPC分类号： C08F2/46 , G02C7/04
CPC分类号： A61F2/1613 , A61F2/142 , A61F2/145 , A61F2/1659 , A61F2240/001 , C08F2/48 , C08F2/50 , G02B1/041
摘要： A process for producing intraocular lenses (IOLs) capable of absorbing blue light and ultraviolet light using photo curing. Intraocular lenses so produced block blue light and ultraviolet light from reaching the retina of an eye implanted with the IOL. By blocking blue light and ultraviolet light from reaching the retina, the IOL thereby prevents potential damage to the retina.
摘要翻译：一种使用光固化能够吸收蓝光和紫外光的人工晶状体（IOL）的制造方法。如此制造的人工晶状体阻挡蓝色光和紫外光到达植入IOL的眼睛的视网膜。通过阻挡蓝光和紫外光到达视网膜，因此IOL可防止对视网膜的潜在损伤。

2. 发明授权

US06454802B1 Intraocular lens implant for the prevention of secondary cataracts 有权
标题翻译：人工晶状体植入物用于预防继发性白内障
公开(公告)号：US06454802B1
公开(公告)日：2002-09-24
申请号：US09642966
申请日：2000-08-21
申请人： Randolph H. Bretton , David P. Vanderbilt , George F. Green
发明人： Randolph H. Bretton , David P. Vanderbilt , George F. Green
IPC分类号： A61F216
CPC分类号： A61L27/50 , A61F2/16 , A61F2002/009 , A61F2002/1699 , A61L2400/18
摘要： A surface treated intraocular lens implant for use in the replacement of a cataractous natural lens to prevent posteriror capsular opacification. The surface treated intraocular lens includes one or more proteins, polypeptides, polyamino acids or polyamines bound to the surface of the intraocular lens implant covalently, non-covalently or a combination thereof. The one or more proteins, polypeptides, polyamino acids or polyamines present on the surface of the intraocular lens implant serves to reduce or eliminate residual lens epithelial cell migration within the lens capsule. By preventing residual lens epithelial cell migration, posterior capsular opacification of the intraocular lens implant is thus reduced or eliminated.
摘要翻译：一种表面处理的眼内晶状体植入物，用于替代白内障天然晶状体以防止后囊膜混浊。表面处理的眼内透镜包括共价，非共价或其组合结合到眼内透镜植入体表面的一种或多种蛋白质，多肽，聚氨基酸或多胺。存在于眼内透镜植入物的表面上的一种或多种蛋白质，多肽，聚氨基酸或多胺用于减少或消除晶状体囊内剩余的晶状体上皮细胞迁移。通过防止残留的晶状体上皮细胞迁移，因此减少或消除了眼内透镜植入物的后囊膜混浊。

3. 发明授权

US06471708B2 Intraocular lens and additive packaging system 失效
公开(公告)号：US06471708B2
公开(公告)日：2002-10-29
申请号：US09746451
申请日：2000-12-21
申请人： George F. Green
发明人： George F. Green
IPC分类号： A61F9007
CPC分类号： A61F2/1662 , A61F2/1691
摘要： A packaging system for an intraocular lens and optionally an additive material that can be used to insert a packaged intraocular lens into an eye through a relatively small incision. Methods for inserting an intraocular lens into an eye using such packaging system are within the scope of the present invention.

4. 发明授权

US06908363B2 Method for target polishing intraocular lenses 失效
标题翻译：目标抛光眼内透镜的方法
公开(公告)号：US06908363B2
公开(公告)日：2005-06-21
申请号：US10184552
申请日：2002-06-27
申请人： George F. Green
发明人： George F. Green
IPC分类号： A61F2/00 , A61F2/16 , B24B13/00 , B24C1/08 , B24C3/22
CPC分类号： A61F2/141 , A61F2/0077 , A61F2/16 , B24B13/00 , B24B13/0006 , B24C1/08 , B24C3/22
摘要： A method for polishing targeted areas of an IOL while leaving other areas unpolished such as sharp posterior edges designed to inhibit PCO. In the preferred embodiment, the polishing method utilizes a stream of polishing agent directed at the IOL which is mounted to a holder during the polishing operation. In this manner, only the targeted areas of the IOL polished while the other areas remain unpolished and sharp as intended. The method is suitable for in-line automated IOL manufacturing.
摘要翻译：抛光IOL的目标区域同时留下其他未被抛光的区域的方法，例如设计成抑制PCO的尖锐后缘。在优选实施例中，抛光方法利用指向在抛光操作期间安装到保持器的IOL的抛光剂流。以这种方式，只有IOL的目标区域抛光，而其他区域保持未被抛光并且如预期那样锋利。该方法适用于在线自动化IOL制造。

5. 发明授权

US06866563B2 Apparatus and method for target polishing intraocular lenses 失效
标题翻译：用于目标抛光眼内透镜的装置和方法
公开(公告)号：US06866563B2
公开(公告)日：2005-03-15
申请号：US10184167
申请日：2002-06-27
申请人： George F. Green
发明人： George F. Green
IPC分类号： B24B13/00 , B24B13/005 , B24B31/00 , B24B1/00
CPC分类号： B24B13/005 , B24B13/00 , B24B31/003
摘要： A mask for removably covering an IOL to protect a sharp peripheral edge of the IOL optic during polishing.
摘要翻译：用于可拆卸地覆盖IOL以在抛光期间保护IOL光学元件的锋利周边边缘的掩模。

6. 发明授权

US06767363B1 Accommodating positive and negative intraocular lens system 有权
标题翻译：适应正，负眼内透镜系统
公开(公告)号：US06767363B1
公开(公告)日：2004-07-27
申请号：US09434635
申请日：1999-11-05
申请人： Mark H. Bandhauer , George F. Green , Donald Carrol Stenger , Michael T. Landreville
发明人： Mark H. Bandhauer , George F. Green , Donald Carrol Stenger , Michael T. Landreville
IPC分类号： A61F216
CPC分类号： B29D11/026 , A61F2/1629 , A61F2/1648 , A61F2002/1681 , A61F2250/0053
摘要： An accommodating intraocular lens system including a higher diopter positive intraocular lens and a lower diopter negative intraocular lens. The positive intraocular lens includes a positive optic portion having an outer peripheral edge and two or more haptic elements. The negative intraocular lens includes a negative optic portion having an outer peripheral edge and two or more haptic elements. Each haptic element is formed to have specific flexibility characteristics so as to be less resistant to bending in a plane generally parallel to an eye's optical axis than in a plane generally perpendicular to the eye's optical axis. The accommodating intraocular lens system is so designed with specific flexibility characteristics to facilitate axial displacement of the positive optic portion with respect to the negative optic portion along the eye's optical axis under a compression force. Through the axial displacement of the positive optic portion with respect to the negative optic portion, accommodative effects are maximized to achieve multi-distance visual imaging.
摘要翻译：包括较高屈光度正性人工晶状体和较低屈光度负性人工晶状体的适应性眼内透镜系统。正面人工晶状体包括具有外周边缘和两个或更多个触觉元件的正光学部分。负的人工晶状体包括具有外周边缘和两个或更多个触觉元件的负光学部分。每个触觉元件形成为具有特定的柔性特性，以便在大致平行于眼睛的光轴的平面中比在大致垂直于眼睛的光轴的平面中的抗弯曲性更差。容纳眼内透镜系统被设计成具有特定的柔性特性，以促进正光学部分在压缩力下沿着眼睛的光轴相对于负光学部分的轴向位移。通过正光学部分相对于负光学部分的轴向位移，最大化调节效应以实现多距离视觉成像。

7. 发明授权

US06558420B2 Durable flexible attachment components for accommodating intraocular lens 失效
公开(公告)号：US06558420B2
公开(公告)日：2003-05-06
申请号：US09735115
申请日：2000-12-12
申请人： George F. Green
发明人： George F. Green
IPC分类号： A61F216
CPC分类号： B29D11/026 , A61F2/1613 , A61F2/1629 , A61F2/1648 , A61F2250/0053 , B29D11/023
摘要： An accommodating intraocular lens including a higher diopter positive intraocular lens and a lower diopter negative intraocular lens. The positive intraocular lens includes a positive optic portion having an outer peripheral edge and two or more polyurethane elastomer flexible attachment components. The negative intraocular lens includes a negative optic portion having an outer peripheral edge and two or more polyurethane elastomer flexible attachment components. Each flexible attachement component is durable and formed to have specific flexibility characteristics so as to be less resistant to bending in a plane generally parallel to an eye's optical axis than in a plane generally perpendicular to the eye's optical axis. The subject durable accommodating intraocular lens enables axial displacement of the positive optic portion with respect to the negative optic portion along the eye's optical axis under a compression force. The flexible attachment components are durable to allow dependable flexation thereof millions of times during a patient's lifetime. Through this flexation of the flexible attachment components and axial displacement of the positive optic portion with respect to the negative optic portion, accommodative effects are maximized to achieve multi-distance visual imaging.

8. 发明授权

US4552816A Process for producing rubber laminates 失效
标题翻译：生产橡胶层压板的方法
公开(公告)号：US4552816A
公开(公告)日：1985-11-12
申请号：US665011
申请日：1984-10-30
申请人： Bojana K. Spahic , George F. Green
发明人： Bojana K. Spahic , George F. Green
IPC分类号： B32B25/08 , C08G18/10 , C08G18/69 , C08J5/12 , C09J175/14 , B32B7/10 , B32B27/40 , B32B31/06
CPC分类号： C09J175/14 , B32B25/08 , C08G18/10 , C08G18/69 , C08J5/124 , Y10T428/31536 , Y10T428/31554 , Y10T428/31569 , Y10T428/31587 , Y10T428/31917 , Y10T428/31924
摘要： The invention discloses a novel process for producing covalently bonded laminated structures composed of polyurethane elastomer and vulcanized rubber layers. As the joining means for covalently bonding the polyurethane elastomer and vulcanizable rubber laminates the process utilizes novel grafted polyurethane joining compositions comprised of polyurethane elastomer, a polyisocyanate, and a hydroxyl containing polybutadiene difunctional linker molecule. In practicing the process of the invention, the grafted polyurethane joining composition is first prepared by means that create covalent chemical bonds between the polyurethane elastomer and a first functional (NCO) group on the polyisocyanate, as well as between a hydroxyl on the polybutadiene difunctional linker molecule and a second functional (NCO) group on the polyisocyanate. This novel grafted polyurethane composition is then used to bond layers of polyurethane elastomer to layers of vulcanizable rubber. In constructing a laminated product, the grafted polyurethane joining composition is interposed between the polyurethane elastomer and vulcanizable rubber layers. The resulting assembly is then heated at a temperature sufficient to allow formation of covalent bonds.
摘要翻译：本发明公开了一种由聚氨酯弹性体和硫化橡胶层组成的共价键合叠层结构的新方法。作为用于共价键合聚氨酯弹性体和可硫化橡胶层压体的接合方法，该方法利用由聚氨酯弹性体，多异氰酸酯和含羟基的聚丁二烯双官能连接分子组成的新型接枝聚氨酯接合组合物。在实施本发明的方法中，接枝聚氨酯接合组合物首先通过在多异氰酸酯之间和聚丁二烯双官能接头之间的羟基之间产生聚氨酯弹性体与第一官能（NCO）基团之间的共价化学键，分子和多异氰酸酯上的第二官能（NCO）基团。然后使用该新型接枝聚氨酯组合物将聚氨酯弹性体层粘合到可硫化橡胶层上。在构造层压制品时，接枝聚氨酯接合组合物介于聚氨酯弹性体和可硫化橡胶层之间。然后将所得组件在足以形成共价键的温度下加热。

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