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1. 发明授权

US06338725B1 Large-diameter introducer sheath having hemostasis valve and removable steering mechanism 有权
公开(公告)号：US06338725B1
公开(公告)日：2002-01-15
申请号：US09158777
申请日：1998-09-23
申请人： George D. Hermann , Kirsten Freislinger , Steven W. Kim , Jay A. Lenker , Michael A. Evans
发明人： George D. Hermann , Kirsten Freislinger , Steven W. Kim , Jay A. Lenker , Michael A. Evans
IPC分类号： A61M3700
CPC分类号： A61M25/0138 , A61B17/12036 , A61B17/12109 , A61B17/12118 , A61B17/12136 , A61F2/07 , A61F2/958 , A61F2002/065 , A61M25/0045 , A61M25/005 , A61M25/0051 , A61M25/0053 , A61M25/0144 , A61M25/0147 , A61M25/0662 , A61M39/0606 , A61M2025/0046 , A61M2025/0681 , A61M2025/1052 , A61M2025/1061 , A61M2039/062 , A61M2039/0633 , A61M2039/0646 , A61M2039/066 , A61M2039/0686 , A61M2210/127
摘要： A catheter introducing system includes an introducer catheter comprising a flexible sheath having a hemostasis valve and an obturator having a steering mechanism operated by a proximal actuator handle. The catheter introducer system will usually be introduced with the obturator inside of the flexible sheath so that the obturator can effect steering by laterally deflecting the distal end of the combined sheath and obturator. Such catheter introducing systems are particularly useful for large diameter sheaths which are not readily introduced over guide wires. A first exemplary hemostasis valve comprises a compressed foam insert having an axial lumen therein. A second exemplary hemostasis valve comprises an elastomeric insert which receives and seals over the catheter.

2. 发明授权

US5599305A Large-diameter introducer sheath having hemostasis valve and removable steering mechanism 失效
标题翻译：具有止血阀和可拆卸转向机构的大直径导引套管
公开(公告)号：US5599305A
公开(公告)日：1997-02-04
申请号：US330140
申请日：1994-10-24
申请人： George D. Hermann , Kirsten Freislinger , Steven W. Kim , Jay A. Lenker , Michael A. Evans
发明人： George D. Hermann , Kirsten Freislinger , Steven W. Kim , Jay A. Lenker , Michael A. Evans
IPC分类号： A61B17/12 , A61F2/06 , A61M25/00 , A61M25/01 , A61M25/06 , A61M39/06 , A61M37/00
CPC分类号： A61M25/0138 , A61B17/12036 , A61B17/12109 , A61B17/12118 , A61B17/12136 , A61M25/0045 , A61M25/0144 , A61M25/0147 , A61M25/0662 , A61M39/0606 , A61F2/07 , A61F2/958 , A61F2002/065 , A61M2025/0046 , A61M2025/0681 , A61M2025/1052 , A61M2025/1061 , A61M2039/062 , A61M2039/0633 , A61M2039/0646 , A61M2039/066 , A61M2039/0686 , A61M2210/127 , A61M25/005 , A61M25/0051 , A61M25/0053
摘要： A catheter introducing system includes an introducer catheter comprising a flexible sheath having a hemostasis valve and an obturator having a steering mechanism operated by a proximal actuator handle. The catheter introducer system will usually be introduced with the obturator inside of the flexible sheath so that the obturator can effect steering by laterally deflecting the distal end of the combined sheath and obturator. Such catheter introducing systems are particularly useful for large diameter sheaths which are not readily introduced over guide wires. A first exemplary hemostasis valve comprises a compressed foam insert having an axial lumen therein. A second exemplary hemostasis valve comprises an elastomeric insert which receives and seals over the catheter.
摘要翻译：导管引入系统包括引导器导管，其包括具有止血阀和闭塞器的柔性护套，该止血阀具有由近侧致动器手柄操作的转向机构。导管导引器系统通常将在柔性护套内部带有闭孔器，使得闭孔器可以通过横向偏转组合护套和闭孔器的远端来实现转向。这种导管引入系统对于不容易在引导线上引入的大直径护套特别有用。第一示例性止血阀包括其中具有轴向腔的压缩泡沫插入件。第二示例性止血阀包括在导管上接收和密封的弹性体插入件。

3. 发明授权

US5843031A Large-diameter introducer sheath having hemostasis valve and removable steering mechanism 失效
公开(公告)号：US5843031A
公开(公告)日：1998-12-01
申请号：US735401
申请日：1996-10-21
申请人： George D. Hermann , Kirsten Freislinger , Steven W. Kim , Jay A. Lenker , Michael A. Evans
发明人： George D. Hermann , Kirsten Freislinger , Steven W. Kim , Jay A. Lenker , Michael A. Evans
IPC分类号： A61B17/12 , A61F2/06 , A61M25/00 , A61M25/01 , A61M25/06 , A61M39/06 , A61M37/00
CPC分类号： A61M25/0138 , A61B17/12036 , A61B17/12109 , A61B17/12118 , A61B17/12136 , A61M25/0045 , A61M25/0144 , A61M25/0147 , A61M25/0662 , A61M39/0606 , A61F2/07 , A61F2/958 , A61F2002/065 , A61M2025/0046 , A61M2025/0681 , A61M2025/1052 , A61M2025/1061 , A61M2039/062 , A61M2039/0633 , A61M2039/0646 , A61M2039/066 , A61M2039/0686 , A61M2210/127 , A61M25/005 , A61M25/0051 , A61M25/0053
摘要： A catheter introducing system includes an introducer catheter comprising a flexible sheath having a hemostasis valve and an obturator having a steering mechanism operated by a proximal actuator handle. The catheter introducer system will usually be introduced with the obturator inside of the flexible sheath so that the obturator can effect steering by laterally deflecting the distal end of the combined sheath and obturator. Such catheter introducing systems are particularly useful for large diameter sheaths which are not readily introduced over guide wires. A first exemplary hemostasis valve comprises a compressed foam insert having an axial lumen therein. A second exemplary hemostasis valve comprises an elastomeric insert which receives and seals over the catheter.

4. 发明授权

US06752154B2 Device for accurately marking tissue 有权
标题翻译：用于准确标记组织的装置
公开(公告)号：US06752154B2
公开(公告)日：2004-06-22
申请号：US09935477
申请日：2001-08-22
申请人： Thomas J. Fogarty , David B. Willis , Thomas A. Howell , George D. Hermann , Peter M. Wilson , Elizabeth M. Bush , Steven W. Kim , Roman Turovskiy
发明人： Thomas J. Fogarty , David B. Willis , Thomas A. Howell , George D. Hermann , Peter M. Wilson , Elizabeth M. Bush , Steven W. Kim , Roman Turovskiy
IPC分类号： A61B1900
CPC分类号： A61B90/39 , A61B17/221 , A61B17/320016 , A61B17/320068 , A61B17/3211 , A61B17/34 , A61B17/3401 , A61B17/3403 , A61B17/3421 , A61B17/3468 , A61B17/3476 , A61B18/14 , A61B18/1477 , A61B18/149 , A61B2017/008 , A61B2017/00849 , A61B2017/00853 , A61B2017/00867 , A61B2017/00929 , A61B2018/1425 , A61B2090/3908
摘要： This invention is an improved tissue localizing device for fixedly yet removably marking a volume of tissue containing a suspect region for excision. This invention also encompasses methods for deployment of the localizing device and its excision along with the marked tissue volume. At least one locator element is deployed into tissue and assumes a predetermined curvilinear shape to define a tissue border containing a suspect tissue region along a path. The locator element path preferably encompasses the distalmost portion of the tissue volume without penetrating that volume. Multiple locator elements may be deployed to further define the tissue volume along additional paths defining the tissue volume border that do not penetrate the volume. Other localization wire embodiments of the invention are disclosed in which the tissue volume may be penetrated by a portion of the device. Polar and tangential deployment configurations as well as a locator element that may be cold-formed by a die in the distal portion of the deployment tube into a permanent arcuate shape are also disclosed.
摘要翻译：本发明是一种改进的组织定位装置，用于固定地可移除地标记包含可疑区域的组织的体积用于切除。本发明还包括用于部署定位装置及其切除以及标记的组织体积的方法。至少一个定位元件被部署到组织中并且呈现预定的曲线形状以限定沿着路径包含可疑组织区域的组织边界。定位元件路径优选地包围组织体积的最远部分而不穿透该体积。可以部署多个定位器元件以进一步沿着限定不穿透该体积的组织体积边界的附加路径限定组织体积。公开了本发明的其它定位线实施例，其中组织体积可以被装置的一部分穿透。还公开了极性和切向部署构造以及可以由展开管的远侧部分中的模具冷成形为永久弓形形状的定位元件。

5. 发明授权

US07322360B2 Device for accurately marking tissue 有权
标题翻译：用于准确标记组织的装置
公开(公告)号：US07322360B2
公开(公告)日：2008-01-29
申请号：US10798776
申请日：2004-03-10
申请人： Thomas J. Fogarty , David Willis , Thomas A. Howell , George D. Hermann , Peter M. Wilson , Elizabeth M. Bush , Steven W. Kim , Roman Turovskiy
发明人： Thomas J. Fogarty , David Willis , Thomas A. Howell , George D. Hermann , Peter M. Wilson , Elizabeth M. Bush , Steven W. Kim , Roman Turovskiy
IPC分类号： A61B19/00
CPC分类号： A61B90/39 , A61B17/221 , A61B17/320016 , A61B17/320068 , A61B17/3211 , A61B17/34 , A61B17/3401 , A61B17/3403 , A61B17/3421 , A61B17/3468 , A61B17/3476 , A61B18/14 , A61B18/1477 , A61B18/149 , A61B2017/008 , A61B2017/00849 , A61B2017/00853 , A61B2017/00867 , A61B2017/00929 , A61B2018/1425 , A61B2090/3908
摘要： This invention is an improved tissue localizing device for fixedly yet removably marking a volume of tissue containing a suspect region for excision. This invention also encompasses methods for deployment of the localizing device and its excision along with the marked tissue volume. At least one locator element is deployed into tissue and assumes a predetermined curvilinear shape to define a tissue border containing a suspect tissue region along a path. The locator element path preferably encompasses the distalmost portion of the tissue volume without penetrating that volume. Multiple locator elements may be deployed to further define the tissue volume along additional paths defining the tissue volume border that do not penetrate the volume. Other localization wire embodiments of the invention are disclosed in which the tissue volume may be penetrated by a portion of the device. Polar and tangential deployment configurations as well as a locator element that may be cold-formed by a die in the distal portion of the deployment tube into a permanent arcuate shape are also disclosed.
摘要翻译：本发明是一种改进的组织定位装置，用于固定地可移除地标记包含可疑区域的组织的体积用于切除。本发明还包括用于部署定位装置及其切除以及标记的组织体积的方法。至少一个定位元件被部署到组织中并且呈现预定的曲线形状以限定沿着路径包含可疑组织区域的组织边界。定位元件路径优选地包围组织体积的最远部分而不穿透该体积。可以部署多个定位器元件以进一步沿着限定不穿透该体积的组织体积边界的附加路径限定组织体积。公开了本发明的其它定位线实施例，其中组织体积可以被装置的一部分穿透。还公开了极性和切向部署构造以及可以由展开管的远侧部分中的模具冷成形为永久弓形形状的定位元件。

6. 发明授权

US08986324B2 Systems and methods for harvesting follicular units 有权
标题翻译：用于收获滤泡单位的系统和方法
公开(公告)号：US08986324B2
公开(公告)日：2015-03-24
申请号：US12855916
申请日：2010-08-13
申请人： Mohan Bodduluri , Kyle R. Breton , Clifford A. Oostman, Jr. , George D. Hermann
发明人： Mohan Bodduluri , Kyle R. Breton , Clifford A. Oostman, Jr. , George D. Hermann
IPC分类号： A61B17/32 , A61B17/34 , A61B17/3205 , A61B17/00
CPC分类号： A61B17/32053 , A61B17/3468 , A61B2017/00752
摘要： Systems and methods are provided for harvesting hair grafts from a body surface utilizing a removal tool comprising first and second elongated bodies. The described systems and methods serve to eliminate and/or at least minimize unnecessary compression of adjacent tissue during the removal process, thereby minimizing damage to the follicular unit being removed, reducing the opportunities for the follicular unit to intersect the path of the harvesting tool, and/or improving the quality of the removed specimen, preferably preserving its integrity.
摘要翻译：提供的系统和方法用于使用包括第一和第二细长体的去除工具从体表收获毛发移植物。所描述的系统和方法用于消除和/或至少最小化在去除过程期间相邻组织的不必要的压缩，从而最小化对被去除的滤泡单元的损伤，减少滤泡单元与收获工具的路径相交的机会，和/或提高去除的样品的质量，优选保持其完整性。

7. 发明授权

US08858415B2 Brachytherapy apparatus and methods for using them 有权
标题翻译：近距离放射治疗仪及其使用方法
公开(公告)号：US08858415B2
公开(公告)日：2014-10-14
申请号：US12764892
申请日：2010-04-21
申请人： Eduardo Chi Sing , George D. Hermann , Mark A. Cole , Mark A. Richart , Than Nguyen , Gail S. Lebovic
发明人： Eduardo Chi Sing , George D. Hermann , Mark A. Cole , Mark A. Richart , Than Nguyen , Gail S. Lebovic
IPC分类号： A61M36/12 , A61N5/10
CPC分类号： A61N5/1015 , A61N2005/1018
摘要： Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.
摘要翻译：用于将近距离放射治疗递送到目标组织区域的装置包括细长主体，其包括近端，远端，其尺寸适于引入到组织道中并且承载多个细长构件，包括用于接收辐射源的路径。细长构件可在折叠和膨胀构型之间移动。在使用期间，通过组织产生管道，并且携带细长构件的细长体通过管道前进到目标位置，细长构件处于收缩构型。细长构件在目标位置处被引导到扩展构型，并且例如通过沿着路径引入一个或多个辐射源，传送辐射以在目标位置处理组织。

8. 发明授权

US08705689B2 Device for cushioning of compression surfaces 有权
标题翻译：压缩表面缓冲装置
公开(公告)号：US08705689B2
公开(公告)日：2014-04-22
申请号：US13351149
申请日：2012-01-16
申请人： Gail Lebovic , George D. Hermann , David Willis , Thomas A. Howell
发明人： Gail Lebovic , George D. Hermann , David Willis , Thomas A. Howell
IPC分类号： A61B6/04
CPC分类号： A61B6/0414 , A61B6/04 , A61B6/0435 , A61B6/4423 , A61B6/502
摘要： According to the present invention, improved methods and apparatus are provided for providing cushioning and other ergonomic surfaces on devices requiring the patient or tissue to be compressed, such as radiography machines, fluoroscopy units, mammography units and the like. In particular a radiolucent pad element is provided for releasable attachment to at least one surface of a compression device to be used under x-ray, for example, during mammography. The pad element of the present invention can be disposable or constructed to be reusable and in some cases may be applied directly to the patient's breast. Furthermore, a cushioned paddle is provided wherein the compression paddle and the cushion can be separately or integrally formed.
摘要翻译：根据本发明，提供了改进的方法和装置，用于在要求患者或组织被压缩的装置上提供缓冲和其它符合人体工程学的表面，例如放射照相机，透视单元，乳房X线照相术单元等。特别地，提供了一种射线可透垫元件，用于可释放地附接到例如在乳房X光照相术期间在x射线下使用的压缩装置的至少一个表面。本发明的垫元件可以是一次性的或构造为可重复使用的，并且在一些情况下可以直接施加到患者的乳房。此外，提供了缓冲桨，其中压缩桨和衬垫可以分开地或一体地形成。

9. 发明申请

US20100046698A1 DEVICE FOR CUSHIONING OF COMPRESSION SURFACES 有权
标题翻译：用于压缩表面的装置
公开(公告)号：US20100046698A1
公开(公告)日：2010-02-25
申请号：US12610303
申请日：2009-10-31
申请人： Gail Lebovic , George D. Hermann , David Willis , Thomas A. Howell
发明人： Gail Lebovic , George D. Hermann , David Willis , Thomas A. Howell
IPC分类号： A61B6/04
CPC分类号： A61B6/0414 , A61B6/04 , A61B6/0435 , A61B6/4423 , A61B6/502
摘要： According to the present invention, improved methods and apparatus are provided for providing cushioning and other ergonomic surfaces on devices requiring the patient or tissue to be compressed, such as radiography machines, fluoroscopy units, mammography units and the like. In particular a radiolucent pad element is provided for releasable attachment to at least one surface of a compression device to be used under x-ray, for example, during mammography. The pad element of the present invention can be disposable or constructed to be reusable and in some cases may be applied directly to the patient's breast. Furthermore, a cushioned paddle is provided wherein the compression paddle and the cushion can be separately or integrally formed.
摘要翻译：根据本发明，提供了改进的方法和装置，用于在要求患者或组织被压缩的装置上提供缓冲和其它符合人体工程学的表面，例如放射照相机，透视单元，乳房X线照相术单元等。特别地，提供了一种射线可透垫元件，用于可释放地附接到例如在乳房X光照相术期间在x射线下使用的压缩装置的至少一个表面。本发明的垫元件可以是一次性的或构造成可重复使用的，并且在一些情况下可以直接施加到患者的乳房。此外，提供了缓冲桨，其中压缩桨和衬垫可以分开地或一体地形成。

10. 发明授权

US06968033B2 Device for cushioning of compression surfaces 有权
标题翻译：压缩表面缓冲装置
公开(公告)号：US06968033B2
公开(公告)日：2005-11-22
申请号：US10389392
申请日：2003-03-14
申请人： Gail Lebovic , George D. Hermann , David Willis , Thomas A. Howell
发明人： Gail Lebovic , George D. Hermann , David Willis , Thomas A. Howell
IPC分类号： A61B6/04 , A61B6/00
CPC分类号： A61B6/0414 , A61B6/04 , A61B6/0435 , A61B6/4423 , A61B6/502
摘要： A compression device for a mammography unit includes a compression plate positionable in an x-ray field of the mammography unit, and a radiolucent foam pad removably attached to the compression plate that includes an impermeable exposed surface for contacting tissue disposed on the pad within the x-ray field. The pad includes an adhesive layer on the first surface, or a hook and eye fastener for removably attaching the pad to the compression plate. The pad is attached to the compression plate in the x-ray field of the mammography unit, a breast is compressed using the compression plate, a mammogram of the compressed breast is obtained, the pad producing no significant visual artifact on the mammogram, and thereafter the pad is removed.
摘要翻译：用于乳房X线照相术单元的压缩装置包括可定位在乳房X线照相术单元的x射线场中的压缩板，以及可移除地附接到压缩板的射线透射泡沫垫，其包括用于接触设置在垫内的组织的不透水暴露表面射击场。垫包括在第一表面上的粘合剂层，或者用于将垫可移除地附接到压缩板的钩和紧固件。垫在乳房X线照相术单元的x射线场附着到压缩板，使用压缩板压缩乳房，获得压缩乳房的乳房X线照片，该垫在乳房X线照片上不产生明显的视觉伪影，此后垫被移除。

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