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1. 发明授权

US07497865B2 Method and apparatus for performing anastomosis with eversion of tissue edges and joining of exposed intima of the everted tissue 失效
标题翻译：用于通过外翻组织边缘进行吻合的方法和装置，以及接合外露组织的暴露内膜
公开(公告)号：US07497865B2
公开(公告)日：2009-03-03
申请号：US10855604
申请日：2004-05-26
申请人： Geoffrey H. Willis , Thomas A. Kramer , Paul A. Spence , George T. Christakis , Timothy J. McCoy , John W. Davis , Bradley D. Blackwood , Peter Callas , Michael Francis Wei , Jonathan L. Podmore , Andrew Knight , Thomas J. Ward , Warren P. Williamson, IV
发明人： Geoffrey H. Willis , Thomas A. Kramer , Paul A. Spence , George T. Christakis , Timothy J. McCoy , John W. Davis , Bradley D. Blackwood , Peter Callas , Michael Francis Wei , Jonathan L. Podmore , Andrew Knight , Thomas J. Ward , Warren P. Williamson, IV
IPC分类号： A61B17/08 , A61B17/10 , A61B17/04
CPC分类号： A61B17/1152 , A61B17/11 , A61B17/115 , A61B2017/1107 , A61B2017/1132 , A61B2017/1135 , A61B2017/1139
摘要： A ring for use in anastomosis. Preferably, the ring is integrally formed from metal, and includes a ring portion and tines and docking members that extend from the ring portion. The ring portion and tines are malleable, and preferably also the docking members are malleable. The ring portion and tines are malleable in the sense that once deformed from a first shape into a second shape, they will not relax back into the first shape from the second. To install the ring in a vessel with the ring portion extending around an incision or other orifice, the tines pierce the tissue around the orifice and are curled against an anvil. The action of curling the tines inverts the tissue near the orifice edges to expose the inside surface of the vessel or organ. Other aspects of the invention are a method and apparatus for installing an anastomosis ring in an incision or other orifice in a vessel or other organ, a method and apparatus for precisely aligning two anastomosis rings (each installed in an incision or other orifice of a different organ) and fastening the aligned rings together. The clips can be crimped onto the aligned rings, or they can be spring clips which are sprung onto the aligned rings to clamp the rings together by spring force. Also within the scope of the invention are crimping and spring clips for use in listening together two aligned anastomosis rings. In other embodiments, the invention is a method for performing an anastomosis by installing an anastomosis ring in an orifice in an organ, installing another anastomosis ring in an orifice in another organ, precisely aligning the two installed anastomosis rings, and fastening the aligned rings together.
摘要翻译：用于吻合的戒指。优选地，环由金属一体地形成，并且包括从环部延伸的环部分和尖齿和对接构件。环形部分和尖齿是可延展的，并且优选的是对接部件是可延展的。环形部分和尖齿在从第一形状变形成第二形状的意义上是可延展的，它们将不会从第二形状放松回第一形状。为了将环安装在具有围绕切口或其他孔口延伸的环部分的容器中，齿刺穿孔周围的组织并且卷绕在砧座上。卷曲尖齿的作用使孔边缘附近的组织反转以暴露血管或器官的内表面。本发明的其它方面是用于将吻合环安装在容器或其他器官中的切口或其它孔中的方法和装置，用于精确地对准两个吻合环（每个安装在切口或不同的其他孔中的其他孔中的方法和装置）器官）并将对准的环固定在一起。夹子可以压接在对准的环上，或者它们可以是弹簧夹，弹簧夹被弹簧上对准的环，以通过弹簧力将环夹在一起。也在本发明的范围内的是压接和弹簧夹，用于一起收听两个对准的吻合环。在其他实施例中，本发明是一种通过在器官中的孔中安装吻合环来进行吻合的方法，在另一个器官的孔中安装另一个吻合环，精确对准两个安装的吻合环，并将对准的环固定在一起。

2. 发明授权

US06811555B1 Method and apparatus for performing anastomosis with eversion of tissue edges and joining of exposed intima of the everted tissue 失效
标题翻译：用于通过外翻组织边缘进行吻合的方法和装置，以及接合外露组织的暴露的内膜
公开(公告)号：US06811555B1
公开(公告)日：2004-11-02
申请号：US09654605
申请日：2000-09-01
申请人： Geoffrey H. Willis , Thomas A. Kramer , Paul A. Spence , George T. Christakis , Timothy J. McCoy , John W. Davis , Bradley D. Blackwood , Peter Callas , Michael Francis Wei , Jonathan L. Podmore , Andrew Knight , Thomas J. Ward , Warren P. Williamson, IV
发明人： Geoffrey H. Willis , Thomas A. Kramer , Paul A. Spence , George T. Christakis , Timothy J. McCoy , John W. Davis , Bradley D. Blackwood , Peter Callas , Michael Francis Wei , Jonathan L. Podmore , Andrew Knight , Thomas J. Ward , Warren P. Williamson, IV
IPC分类号： A61B1708
CPC分类号： A61B17/1152 , A61B17/11 , A61B17/115 , A61B2017/1107 , A61B2017/1132 , A61B2017/1135 , A61B2017/1139
摘要： A ring for use in anastomosis. Preferably, the ring is integrally formed from metal, and includes a ring portion and tines and docking members that extend from the ring portion. The ring portion and tines are malleable, and preferably also the docking members are malleable. The ring portion and tines are malleable in the sense that once deformed from a first shape into a second shape, they will not relax back into the first shape from the second. To install the ring in a vessel with the ring portion extending around an incision or other orifice, the tines pierce the tissue around the orifice and are curled against an anvil. The action of curling the tines inverts the tissue near the orifice edges to expose the inside surface of the vessel or organ. Other aspects of the invention are a method and apparatus for installing an anastomosis ring in an incision or other orifice in a vessel or other organ, a method and apparatus for precisely aligning two anastomosis rings (each installed in an incision or other orifice of a different organ) and fastening the aligned rings together. The clips can be crimped onto the aligned rings, or they can be spring clips which are sprung onto the aligned rings to clamp the rings together by spring force. Also within the scope of the invention are crimping and spring clips for use in fastening together two aligned anastomosis rings. In other embodiments, the invention is a method for performing an anastomosis by installing an anastomosis ring in an orifice in an organ, installing another anastomosis ring in an orifice in another organ, precisely aligning the two installed anastomosis rings, and fastening the aligned rings together.
摘要翻译：用于吻合的戒指。优选地，环由金属一体地形成，并且包括从环部延伸的环部分和尖齿和对接构件。环形部分和尖齿是可延展的，并且优选的是对接部件是可延展的。环形部分和尖齿在从第一形状变形成第二形状的意义上是可延展的，它们将不会从第二形状放松回第一形状。为了将环安装在具有围绕切口或其他孔口延伸的环部分的容器中，齿刺穿孔周围的组织并且卷绕在砧座上。卷曲尖齿的作用使孔边缘附近的组织反转以暴露血管或器官的内表面。本发明的其它方面是用于将吻合环安装在容器或其他器官中的切口或其它孔中的方法和装置，用于精确地对准两个吻合环（每个安装在切口或不同的其他孔中的其他孔中的方法和装置）器官）并将对准的环固定在一起。夹子可以压接在对准的环上，或者它们可以是弹簧夹，弹簧夹被弹簧上对准的环，以通过弹簧力将环夹在一起。也在本发明的范围内的是压接和弹簧夹，用于将两个对准的吻合环紧固在一起。在其他实施例中，本发明是一种通过在器官中的孔中安装吻合环来进行吻合的方法，在另一个器官的孔中安装另一个吻合环，精确对准两个安装的吻合环，并将对准的环固定在一起。

3. 发明授权

US10543073B2 System and methods for closing a fascial opening 有权
公开(公告)号：US10543073B2
公开(公告)日：2020-01-28
申请号：US15802396
申请日：2017-11-02
申请人： Albert K Chin , Thomas A. Kramer
发明人： Albert K Chin , Thomas A. Kramer
IPC分类号： A61B17/02 , A61F2/00 , A61B17/00
摘要： A system and method for closing a fascial opening is disclosed. The system may include a strap that may be locked into each of a pair of anchors placed anterior to a muscle and on opposite sides of a fascial opening, one or more delivery tubes for delivering the anchors, and a needle for pulling the strap into each anchor. The method may include the steps of placing a dilating port through a skin incision, inserting an anchor through the dilating port, placing a strap into the body cavity, whereupon the strap may be pulled through the anchor. A second anchor may be placed on the contralateral side of the defect so that the strap may be pulled through the second anchor and cinched tightly closing the defect. The anchors may have a locking aperture that engages with the strap.

4. 发明授权

US5964772A Applicator for attaching fasteners to tissue 失效
标题翻译：用于将紧固件固定到组织上的敷料器
公开(公告)号：US5964772A
公开(公告)日：1999-10-12
申请号：US812958
申请日：1997-03-05
申请人： Lee Bolduc , Thomas A. Kramer , Brian A. Hodges , Tim McCoy , John Lunsford
发明人： Lee Bolduc , Thomas A. Kramer , Brian A. Hodges , Tim McCoy , John Lunsford
IPC分类号： A61B17/08 , A61B17/00 , A61B17/04 , A61B17/06 , A61B17/064 , A61B17/068 , A61B17/072 , A61B17/10 , A61B17/128 , A61F2/00
CPC分类号： A61B17/064 , A61B17/068 , A61B17/0469 , A61B17/1285 , A61B2017/00004 , A61B2017/06076 , A61B2017/06171 , A61B2017/0649 , A61F2/0063 , Y10S227/901 , Y10S227/902 , Y10S606/91 , Y10S606/916
摘要： A helical fastener having a high retentive surface area is provided and has a first end for enhancing penetration into tissue and a second end comprising a coil sectioning a diameter of the fastener for receiving longitudinal and rotational forces. The helical fasteners are attached to body tissue by a fastener applicator having a proximal portion comprising a handle and an actuator and an elongate distal portion for housing a plurality of fasteners. A transferring action of the actuator provides longitudinal and rotational movement of the fasteners out of the distal portion and into body tissue.
摘要翻译：提供具有高保持表面积的螺旋紧固件，并具有用于增强穿入组织的第一端和包括用于接收纵向和旋转力的用于紧固紧固件的直径的线圈的第二端。螺旋紧固件通过紧固件施用器附接到身体组织，所述紧固件施加器具有包括手柄和致动器的近侧部分和用于容纳多个紧固件的细长远侧部分。致动器的转移动作提供紧固件从远端部分到身体组织的纵向和旋转运动。

5. 发明申请

US20110213290A1 Systems and Methods for Removing Undesirable Material Within a Circulatory System 审中-公开
标题翻译：在循环系统中去除不希望的材料的系统和方法
公开(公告)号：US20110213290A1
公开(公告)日：2011-09-01
申请号：US13081184
申请日：2011-04-06
申请人： Albert K. Chin , Lishan Aklog , Brian deGuzman , Thomas A. Kramer , Michael Glennon
发明人： Albert K. Chin , Lishan Aklog , Brian deGuzman , Thomas A. Kramer , Michael Glennon
IPC分类号： A61M1/00
CPC分类号： A61B17/22 , A61B17/22032 , A61B17/3207 , A61B2017/22079 , A61B2017/22094 , A61B2017/2215 , A61M1/0056 , A61M1/0058 , A61M1/3621 , A61M25/0032 , A61M25/0074 , A61M25/10 , A61M2025/0031 , A61M2025/0079 , A61M2205/7545
摘要： A system for removing undesirable material from vessels and from chambers within the heart is provided. The system includes a suction cannula for removing the undesirable material from a site of interest within a patient. A filter device may be provided for capturing the undesirable material and removing it from the fluid flow. The system also includes pump for generating the necessary suction force through the suction cannula to dislodge the undesirable material from the site of interest and for generating a sufficient driving force to direct the fluid flow downstream within the system. The system further includes a reinfusion cannula for introducing fluid removed from the site of interest back into a patient. A method for removing undesirable material from vessels and from heart chambers is also provided.
摘要翻译：提供了用于从血管和心脏内的室除去不需要的物质的系统。该系统包括用于从患者体内感兴趣的部位移除不需要的材料的抽吸插管。可以提供过滤装置用于捕获不期望的材料并将其从流体流中移出。该系统还包括用于通过抽吸套管产生必要的吸力的泵，用于从不期望的位置移除不需要的材料，并产生足够的驱动力以将流体流引向系统内的下游。该系统还包括用于将从感兴趣部位移除的流体引入患者体内的再灌注插管。还提供了用于从血管和心室除去不需要的物质的方法。

6. 发明授权

US5582616A Surgical helical fastener with applicator 失效
公开(公告)号：US5582616A
公开(公告)日：1996-12-10
申请号：US286878
申请日：1994-08-05
申请人： Lee Bolduc , Thomas A. Kramer , Brian A. Hodges , Tim McCoy , John Lunsford
发明人： Lee Bolduc , Thomas A. Kramer , Brian A. Hodges , Tim McCoy , John Lunsford
IPC分类号： A61B17/08 , A61B17/00 , A61B17/04 , A61B17/06 , A61B17/064 , A61B17/068 , A61B17/072 , A61B17/10 , A61B17/128 , A61F2/00
CPC分类号： A61B17/064 , A61B17/068 , A61B17/0469 , A61B17/1285 , A61B2017/00004 , A61B2017/06076 , A61B2017/06171 , A61B2017/0649 , A61F2/0063 , Y10S227/901 , Y10S227/902 , Y10S606/91 , Y10S606/916
摘要： A helical fastener having a high retentive surface area is provided and has a first end for enhancing penetration into tissue and a second end comprising a coil sectioning a diameter of the fastener for receiving longitudinal and rotational forces. The helical fasteners are attached to body tissue by a fastener applicator having a proximal portion comprising a handle and an actuator and an elongate distal portion for housing a plurality of fasteners. A transferring action of the actuator provides longitudinal and rotational movement of the fasteners out of the distal portion and into body tissue.

7. 发明申请

US20180116778A1 SYSTEM AND METHODS FOR CLOSING A FASCIAL OPENING 审中-公开
公开(公告)号：US20180116778A1
公开(公告)日：2018-05-03
申请号：US15802396
申请日：2017-11-02
申请人： Albert K. Chin , Thomas A. Kramer
发明人： Albert K. Chin , Thomas A. Kramer
IPC分类号： A61F2/00 , A61B17/02
CPC分类号： A61F2/0063 , A61B17/0218 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/3423 , A61B2017/00407 , A61B2017/00637 , A61B2017/00641 , A61B2017/00663 , A61B2017/00818 , A61B2017/00862 , A61B2017/0225 , A61B2017/0409 , A61B2017/0419 , A61B2017/0461 , A61B2017/0464 , A61B2017/06176 , A61B2017/349 , A61F2002/0072 , A61F2220/0008 , A61F2220/0091
摘要： A system and method for closing a fascial opening is disclosed. The system may include a strap that may be locked into each of a pair of anchors placed anterior to a muscle and on opposite sides of a fascial opening, one or more delivery tubes for delivering the anchors, and a needle for pulling the strap into each anchor. The method may include the steps of placing a dilating port through a skin incision, inserting an anchor through the dilating port, placing a strap into the body cavity, whereupon the strap may be pulled through the anchor. A second anchor may be placed on the contralateral side of the defect so that the strap may be pulled through the second anchor and cinched tightly closing the defect. The anchors may have a locking aperture that engages with the strap.

8. 发明授权

US09326790B2 Catheter with vessel lining and methods for using same 有权
公开(公告)号：US09326790B2
公开(公告)日：2016-05-03
申请号：US14073270
申请日：2013-11-06
申请人： Albert K. Chin , Thomas A. Kramer
发明人： Albert K. Chin , Thomas A. Kramer
IPC分类号： A61M29/00 , A61B17/34 , A61M25/06 , A61M25/01 , A61M25/10
CPC分类号： A61B17/3439 , A61B17/3403 , A61B17/3468 , A61M25/0119 , A61M25/0662 , A61M25/1006 , A61M25/104 , A61M2025/0681 , A61M2025/1081
摘要： A system for providing access across a site of obstruction is provided. The system may include a sleeve, having a distal portion that can move from an inverted position to an everted position. A balloon situated within the sleeve can be extended so as to evert sleeve. A pathway can extend across a juncture between the distal portion and the remaining portion of the sleeve so as to provide access across the site of obstruction. A method for providing access across the site of obstruction is also provided.

9. 发明申请

US20140200598A1 DEVICES AND SYSTEMS CONFIGURED TO FIT AROUND A TISSUE OR ORGAN AND METHODS OF USING THE SAME 有权
标题翻译：配置在组织或有机体附近的装置和系统及其使用方法
公开(公告)号：US20140200598A1
公开(公告)日：2014-07-17
申请号：US14215829
申请日：2014-03-17
申请人： Ghassan S. Kassab , Thomas A. Kramer
发明人： Ghassan S. Kassab , Thomas A. Kramer
IPC分类号： A61F5/00 , A61B17/122
CPC分类号： A61F5/0086 , A61B17/122 , A61B17/1227 , A61F5/0013
摘要： Devices and systems to fit around a tissue or organ and methods of using the same. In at least one embodiment of an implantable device of the present disclosure, the implantable device comprises a first engaging component comprising a first rigid inner plate at least partially surrounded by a first flexible coating, a second engaging component comprising a second rigid inner plate at least partially surrounded by a coating selected from the group consisting of the first flexible coating and the second flexible coating, a first c-ring and a second c-ring coupled to the engaging components, and a cover flap coupled to either the first engaging component or the second engaging component and capable of either further coupling to the second engaging component when initially coupled to the first engaging component or further coupling to the first engaging component when initially coupled to the second engaging component.
摘要翻译：围绕组织或器官的装置和系统及其使用方法。在本公开的可植入装置的至少一个实施例中，可植入装置包括第一接合部件，其包括至少部分地被第一柔性涂层包围的第一刚性内板，第二接合部件至少包括第二刚性内板部分地由选自第一柔性涂层和第二柔性涂层的涂层包围，耦合到接合部件的第一c环和第二c形环，以及联接到第一接合部件或第二接合部件，并且能够在最初耦合到第一接合部件时进一步联接到第二接合部件，或者当初始耦合到第二接合部件时进一步联接到第一接合部件。

10. 发明申请

US20140066961A1 Catheter with Vessel Lining and Methods for Using Same 有权
标题翻译：血管内衬导管及其使用方法
公开(公告)号：US20140066961A1
公开(公告)日：2014-03-06
申请号：US14073270
申请日：2013-11-06
申请人： Albert K. Chin , Thomas A. Kramer
发明人： Albert K. Chin , Thomas A. Kramer
IPC分类号： A61B17/34
CPC分类号： A61B17/3439 , A61B17/3403 , A61B17/3468 , A61M25/0119 , A61M25/0662 , A61M25/1006 , A61M25/104 , A61M2025/0681 , A61M2025/1081
摘要： A system for providing access across a site of obstruction is provided. The system may include a sleeve, having a distal portion that can move from an inverted position to an everted position. A balloon situated within the sleeve can be extended so as to evert sleeve. A pathway can extend across a juncture between the distal portion and the remaining portion of the sleeve so as to provide access across the site of obstruction. A method for providing access across the site of obstruction is also provided.
摘要翻译：提供了一种用于提供跨阻塞位置的通路的系统。该系统可以包括套筒，其具有可以从倒置位置移动到转动位置的远侧部分。位于套筒内的气囊可以延伸以使套筒翻转。通路可以延伸穿过套管的远侧部分和其余部分之间的交界处，以便提供通过阻塞部位的通路。还提供了一种用于提供跨阻塞部位的通路的方法。

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