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    • 2. 发明申请
    • SYSTEMS AND METHODS FOR DELIVERING A MEDICAMENT
    • 用于输送药物的系统和方法
    • US20100094195A1
    • 2010-04-15
    • US12281495
    • 2007-03-02
    • Gene Edward AustinSied W. JannaJames K. RainsJohn NMI RoseLee Whitehurst
    • Gene Edward AustinSied W. JannaJames K. RainsJohn NMI RoseLee Whitehurst
    • A61M5/00A61B18/18A61H1/00
    • A61L27/54A61K9/0009A61K9/0024A61L27/34A61L27/50A61L2300/608
    • A medicament containment device (106) is provided containing a medicament (114) and is associated with an implant, such as an orthopaedic implant (102). The medicament containment device (106) can degrade upon exposure to energy, such as energy (112) from an energy source (110). The orthopaedic implant (102), including the medicament containment device is implanted or inserted into an environment (100) such as a patient's body. The energy source (110) can be used outside the patient's body, but in proximity to the orthopaedic implant (102), to apply energy (112) to the medicament containment device (106). Upon exposure to the energy (112), the medicament containment device (106) can degrade and release the medicament (114) into the environment (100). The medicament (114) can kill and/or disrupt bacterial cells (108) or other infectious cells that form in proximity to the orthopaedic implant (102).
    • 提供了药物容纳装置(106),其包含药物(114)并且与诸如整形外科植入物(102)的植入物相关联。 药物容纳装置(106)在暴露于来自能量源(110)的能量(例如能量(112))时可能降解。 包括药物容纳装置的整形外科植入物(102)被植入或插入诸如患者身体的环境(100)中。 能量源(110)可以在患者身体外部使用,但是在矫形外科植入物(102)附近,以将能量(112)施加到药物容纳装置(106)。 在暴露于能量(112)时,药物容纳装置(106)可以将药物(114)降解并释放到环境(100)中。 药物(114)可以杀死和/或破坏在整形外科植入物(102)附近形成的细菌细胞(108)或其它感染性细胞。