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1. 发明授权

US10829824B2 Compositions, kits and methods for detection of campylobacter nucleic acid 有权
公开(公告)号：US10829824B2
公开(公告)日：2020-11-10
申请号：US14927785
申请日：2015-10-30
申请人： Gen-Probe Incorporated
发明人： Michael R. Reshatoff, Jr. , Jennifer J. Bungo , Shannon K. Kaplan , James J. Hogan
IPC分类号： C12Q1/68 , C12Q1/689
摘要： The disclosed invention is related to compositions, kits and methods comprising one or more oligomers targeting 16S rRNA target nucleic acid from Campylobacter species jejuni, coli and/or lari. Compositions include amplification oligomers, detection probe oligomers and/or target capture oligomers. Kits and methods comprise at least one of these oligomers.

2. 发明授权

US10689712B2 Compositions and methods for detecting nucleic acid from Mollicutes 有权
公开(公告)号：US10689712B2
公开(公告)日：2020-06-23
申请号：US15699502
申请日：2017-09-08
申请人： Gen-Probe Incorporated
发明人： Shannon K. Kaplan , Kristin W. Livezey , Michael M. Becker , James J. Hogan
IPC分类号： C12Q1/68 , C12Q1/689
摘要： Compositions, reaction mixtures, kits and methods used in amplifying and detecting nucleic acids from various species of the class Mollicutes. Particular regions of the 23S rRNA or its gene have been identified as preferred targets for nucleic acid amplification reactions of a sample suspected containing at least one species of Mollicutes. Some oligomers comprise tag regions, target closing regions, promoter sequences, and/or binding moieties. Samples can be from any source suspected of containing a species of the class Mollicutes. Preferred sample sources include bioreactors, cell lines, cell culture wares and pharmaceutical manufacturing wares.

3. 发明授权

US10626466B2 Compositions, kits and related methods for the detection and/or monitoring of 有权
公开(公告)号：US10626466B2
公开(公告)日：2020-04-21
申请号：US14581919
申请日：2014-12-23
申请人： Gen-Probe Incorporated
发明人： Shannon K. Kaplan , Kristin Livezey , Jennifer J. Bungo , James J. Hogan
IPC分类号： C12Q1/689
CPC分类号： C12Q1/689
摘要： The present invention provides compositions, methods and kits for the species-specific detection of Pseudomonas aeruginosa.

4. 发明授权

US12104213B2 Compositions, kits and methods for detection of campylobacter nucleic acid 有权
公开(公告)号：US12104213B2
公开(公告)日：2024-10-01
申请号：US16933341
申请日：2020-07-20
申请人： GEN-PROBE INCORPORATED
发明人： Michael R. Reshatoff, Jr. , Jennifer J. Bungo , Shannon K. Kaplan , James J. Hogan
IPC分类号： C12Q1/68 , C12Q1/689
CPC分类号： C12Q1/689 , C12Q2600/158 , Y02A50/30
摘要： The disclosed invention is related to compositions, kits and methods comprising one or more oligomers targeting 16S rRNA target nucleic acid from Campylobacter species jejuni, coli and/or lari. Compositions include amplification oligomers, detection probe oligomers and/or target capture oligomers. Kits and methods comprise at least one of these oligomers.

5. 发明授权

US09920382B2 Compositions and methods for detecting nucleic acid from mollicutes 有权
公开(公告)号：US09920382B2
公开(公告)日：2018-03-20
申请号：US14938630
申请日：2015-11-11
申请人： Gen-Probe Incorporated
发明人： Shannon K. Kaplan , Kristin W. Livezey , Michael M. Becker , James J. Hogan
IPC分类号： C12Q1/68
CPC分类号： C12Q1/689 , C12Q2600/16
摘要： Compositions, reaction mixtures, kits and methods used in amplifying and detecting nucleic acids from various species of the class Mollicutes. Particular regions of the 23S rRNA or its gene have been identified as preferred targets for nucleic acid amplification reactions of a sample suspected containing at least one species of Mollicutes. Some oligomers comprise tag regions, target closing regions, promoter sequences, and/or binding moieties. Samples can be from any source suspected of containing a species of the class Mollicutes. Preferred sample sources include bioreactors, cell lines, cell culture wares and pharmaceutical manufacturing wares.

6. 发明申请

US20140113289A1 COMPOSITIONS AND METHODS TO DETECT LEGIONELLA PNEUMOPHILA NUCLEIC ACID 有权
标题翻译：组合物和检测LEGIONELLA PNEUMOPHILA核酸的方法
公开(公告)号：US20140113289A1
公开(公告)日：2014-04-24
申请号：US14075944
申请日：2013-11-08
申请人： Gen-Probe Incorporated
发明人： Jennifer J. Bungo , James J. Hogan , Reinhold B. Pollner , Marie K. Hudspeth , Shannon K. Kaplan , Elizabeth M. Marlowe
IPC分类号： C12Q1/68
CPC分类号： C12Q1/689 , C12Q1/686 , Y02A50/451
摘要： Compositions are disclosed as nucleic acid sequences that may be used as amplification oligomers, including primers, and detection probes that hybridize specifically to Legionella pneumophila 23S rRNA sequences or DNA encoding 23S rRNA. Reaction mixtures are disclosed that contain oligonucleotides for the in vitro amplification and/or detection of Legionella pneumophila 23S rRNA sequences or DNA encoding 23S rRNA. Methods are disclosed for amplifying and/or detecting the presence of L. pnuemophila in samples by using the disclosed compositions in in vitro methods that include nucleic acid amplification and/or detection of a 23S rRNA sequence or DNA encoding the 23S rRNA sequence to produce a detectable amplification product. Reaction mixtures are disclosed that contain oligonucleotides for the in vitro amplification and/or detection of Legionella pneumophila 23S rRNA sequences or DNA encoding 23S rRNA.
摘要翻译：公开了组合物作为可用作扩增寡聚物的核酸序列，包括引物和与嗜肺军团菌23S rRNA序列或编码23S rRNA的DNA特异性杂交的检测探针。公开了含有用于体外扩增和/或检测嗜肺军团菌23S rRNA序列或编码23S rRNA的DNA的寡核苷酸的反应混合物。公开了用于通过使用所公开的组合物在体外方法中扩增和/或检测样品中存在嗜血杆菌的方法，其包括核酸扩增和/或检测23S rRNA序列或编码23S rRNA序列的DNA以产生可检测扩增产物。公开了含有用于体外扩增和/或检测嗜肺军团菌23S rRNA序列或编码23S rRNA的DNA的寡核苷酸的反应混合物。

7. 发明授权

US10626470B2 Compositions and methods to detect 有权
公开(公告)号：US10626470B2
公开(公告)日：2020-04-21
申请号：US15811364
申请日：2017-11-13
申请人： GEN-PROBE INCORPORATED
发明人： Jennifer J. Bungo , James J. Hogan , Reinhold B. Pollner , Marie K. Hudspeth , Shannon K. Kaplan , Elizabeth M. Marlowe
IPC分类号： C12Q1/689 , C12Q1/686
CPC分类号： C12Q1/689 , C12Q1/686 , Y02A50/451
摘要： Compositions are disclosed as nucleic acid sequences that may be used as amplification oligomers, including primers, capture probes for sample preparation, and detection probes specific for Legionella pneumophila 16S or 23S rRNA sequences or DNA encoding 16S or 23S rRNA. Methods are disclosed for detecting the presence of L. pneumophila in samples by using the disclosed compositions in methods that include in vitro nucleic acid amplification of a 16S rRNA sequence or DNA encoding the 16S rRNA sequence, or of a 23S rRNA sequence or DNA encoding the 23S rRNA sequence to produce a detectable amplification product.

8. 发明授权

US09845509B2 Compositions and methods to detect Legionella pneumophila nucleic acid 有权
公开(公告)号：US09845509B2
公开(公告)日：2017-12-19
申请号：US14075944
申请日：2013-11-08
申请人： Gen-Probe Incorporated
发明人： Jennifer J. Bungo , James J. Hogan , Reinhold B. Pollner , Marie K. Hudspeth , Shannon K. Kaplan , Elizabeth M. Marlowe
IPC分类号： C12Q1/68
CPC分类号： C12Q1/689 , C12Q1/686 , Y02A50/451
摘要： Compositions are disclosed as nucleic acid sequences that may be used as amplification oligomers, including primers, and detection probes that hybridize specifically to Legionella pneumophila 23S rRNA sequences or DNA encoding 23S rRNA. Reaction mixtures are disclosed that contain oligonucleotides for the in vitro amplification and/or detection of Legionella pneumophila 23S rRNA sequences or DNA encoding 23S rRNA. Methods are disclosed for amplifying and/or detecting the presence of L. pnuemophila in samples by using the disclosed compositions in in vitro methods that include nucleic acid amplification and/or detection of a 23S rRNA sequence or DNA encoding the 23S rRNA sequence to produce a detectable amplification product. Reaction mixtures are disclosed that contain oligonucleotides for the in vitro amplification and/or detection of Legionella pneumophila 23S rRNA sequences or DNA encoding 23S rRNA.

9. 发明授权

US09765403B2 Compositions and methods for detecting nucleic acid from mollicutes 有权
公开(公告)号：US09765403B2
公开(公告)日：2017-09-19
申请号：US14938630
申请日：2015-11-11
申请人： Gen-Probe Incorporated
发明人： Shannon K. Kaplan , Kristin W. Livezey , Michael M. Becker , James J. Hogan
IPC分类号： C12Q1/68
摘要： Compositions, reaction mixtures, kits and methods used in amplifying and detecting nucleic acids from various species of the class Mollicutes. Particular regions of the 23S rRNA or its gene have been identified as preferred targets for nucleic acid amplification reactions of a sample suspected containing at least one species of Mollicutes. Some oligomers comprise tag regions, target closing regions, promoter sequences, and/or binding moieties. Samples can be from any source suspected of containing a species of the class Mollicutes. Preferred sample sources include bioreactors, cell lines, cell culture wares and pharmaceutical manufacturing wares.

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