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1. 发明授权

US07296567B2 Breath actuated aerosol dispensers 失效
标题翻译：呼吸气雾剂分配器
公开(公告)号：US07296567B2
公开(公告)日：2007-11-20
申请号：US10529324
申请日：2003-09-15
申请人： Gary D. Mahon , Eric A. Baum , Andrew M. Bryant
发明人： Gary D. Mahon , Eric A. Baum , Andrew M. Bryant
IPC分类号： A61M11/00
CPC分类号： A61M15/0091 , A61M15/009
摘要： A breath actuated metered dose inhaler device for use with an aerosol valve having a transient metering chamber.
摘要翻译：用于与具有瞬时计量室的气溶胶阀一起使用的呼吸致动计量剂量吸入器装置。

2. 发明授权

US06863195B2 Valve stem for use in a metering valve of a metered dose inhaler 失效
标题翻译：用于定量吸入器计量阀的阀杆
公开(公告)号：US06863195B2
公开(公告)日：2005-03-08
申请号：US10334375
申请日：2002-12-30
申请人： Andrew M. Bryant , Gustavo H. Castro , David J. Greenleaf , Peter D. Hodson , Gary D. Mahon
发明人： Andrew M. Bryant , Gustavo H. Castro , David J. Greenleaf , Peter D. Hodson , Gary D. Mahon
IPC分类号： B65D83/44 , B65D83/14 , G01F11/12 , G01R11/12 , B65D83/00
CPC分类号： B65D83/54 , G01F11/12 , G01R11/12
摘要： Valve stems for use in an aerosol metering valve are described herein. The valve stems include structures designed to limit the likelihood and extent to which a gasket can intrude into an opening in the valve stem. The valve stems described herein also limit the likelihood and extent of damage to the gasket caused by repeated use of the metering valve.
摘要翻译：本文描述了用于气溶胶计量阀的阀杆。阀杆包括设计成限制垫圈可能侵入阀杆中的开口的可能性和程度的结构。本文所述的阀杆还限制了由于重复使用计量阀而导致的垫圈损坏的可能性和程度。

3. 发明授权

US5511540A Inhalation device 失效
标题翻译：吸入装置
公开(公告)号：US5511540A
公开(公告)日：1996-04-30
申请号：US381867
申请日：1995-02-15
申请人： Andrew M. Bryant , Anthony C. L. Wass , Guenter M. Zilligan
发明人： Andrew M. Bryant , Anthony C. L. Wass , Guenter M. Zilligan
IPC分类号： A61M15/00 , A61M11/00
CPC分类号： A61M15/0091
摘要： A breath-actuated aerosol dispenser having a spring to provide the priming force which is held in a partially compressed state within a cage such that the spring applies no force to an aerosol container, valve, or triggering mechanism included in the dispenser while the dispenser is in its rest position.
摘要翻译： PCT No.PCT / GB93 / 01754 Sec。 371日期1995年2月15日 102（e）日期1995年2月15日PCT提交1993年8月18日PCT公布。出版物WO94 / 04209 日期：1994年3月3日。一种呼吸致动的气溶胶分配器，其具有弹簧以提供起动力，该起动力在笼中保持在部分压缩状态，使得弹簧不施加于气溶胶容器，阀或触发机构在分配器处于其静止位置时在分配器中。

4. 发明授权

US06644517B2 Stem configuration to reduce seal abrasion in metered dose aerosol valves 有权
公开(公告)号：US06644517B2
公开(公告)日：2003-11-11
申请号：US09978816
申请日：2001-10-15
申请人： Charles G. Thiel , Peter D. Hodson , Andrew M. Bryant
发明人： Charles G. Thiel , Peter D. Hodson , Andrew M. Bryant
IPC分类号： B65D8314
CPC分类号： B65D83/48 , A61M15/009 , B65D83/54
摘要： A valve stem for use in an aerosol valve such as a metered dose medicinal aerosol valve is described. The valve stem includes a flattened area around the side hole. The flattened area helps reduce damage to the diaphragm aperture upon repeated actuation of the metered dose inhaler. Also described is a metered dose valve and a metered dose inhaler, each including the flattened valve stem of the present invention.

5. 发明授权

US06460537B1 Breath-actuated aerosol dispensers 失效
标题翻译：呼吸式气雾剂分配器
公开(公告)号：US06460537B1
公开(公告)日：2002-10-08
申请号：US09437047
申请日：1999-11-09
申请人： Andrew M. Bryant , Anthony C. L. Wass , Peter D. Hodson
发明人： Andrew M. Bryant , Anthony C. L. Wass , Peter D. Hodson
IPC分类号： A61M1100
CPC分类号： A61M15/0091 , A61M15/0081 , A61M15/009 , A61M15/0093
摘要： A dispenser for dispensing a product from a pressurized product container comprising a housing defining a user port and adapted to have a pressurized product container mounted therein, the pressurized product container having a dispensing valve movable relative to the container between an open and a closed position; the housing further comprising a rolling member comprising a vane, and two associated rolling surfaces, the rolling member being capable of rotation in contact with the rolling surfaces such that they translate in opposite directions relative to the rolling member in response to inhalation through the user port, the rolling member being rotatable between a locking position in which the rolling member directly or indirectly engages the pressurized product container or valve to maintain the valve in the closed position, and a release position in which the valve and the pressurized product container move relative to each other so that the valve moves to the open position to dispense product from the container and towards the user port.
摘要翻译：一种用于从加压产品容器分配产品的分配器，包括限定用户端口并适于安装在其中的加压产品容器的壳体，所述加压产品容器具有可在打开和关闭位置之间相对于容器移动的分配阀; 所述壳体还包括滚动构件，所述滚动构件包括叶片和两个相关联的滚动表面，所述滚动构件能够旋转地与所述滚动表面接触，使得所述滚动构件响应于通过所述用户端口的吸入而相对于所述滚动构件在相反方向上平移所述滚动构件可在锁定位置之间旋转，在所述锁定位置中，所述滚动构件直接或间接地接合所述加压产品容器或阀，以将所述阀保持在关闭位置;以及释放位置，其中所述阀和所述加压产品容器相对于彼此使得阀移动到打开位置以从容器和用户端口分配产品。

6. 发明授权

US5623920A Valve assemblies 失效
标题翻译：阀组件
公开(公告)号：US5623920A
公开(公告)日：1997-04-29
申请号：US362520
申请日：1995-01-06
申请人： Andrew M. Bryant
发明人： Andrew M. Bryant
IPC分类号： A61M15/00 , B65D83/14 , A61M11/00
CPC分类号： B65D83/54 , A61M15/0091 , B65D83/425
摘要： A valve assembly for a pressurized aerosol container which has a neutral bias. The valve may be of the metered dose type and is preferably springless. Containers equipped with such valves may be employed in breath actuated dispensing devices with simplified mechanisms since it is not necessary to overcome any biasing force within the valve.
摘要翻译： PCT No.PCT / GB93 / 01458 Sec。 371 1995年1月6日第 102（e）日期1995年1月6日PCT提交1993年7月13日PCT公布。第WO94 / 01347号公报日期1994年1月20日用于具有中性偏压的加压气溶胶容器的阀组件。阀可以是计量剂型，优选是无弹簧的。配备有这种阀的容器可以采用具有简化机构的呼吸促动分配装置，因为不需要克服阀内的任何偏压力。

7. 发明授权

US5772085A Free flow aerosol valves 失效
标题翻译：自由流动气溶胶阀
公开(公告)号：US5772085A
公开(公告)日：1998-06-30
申请号：US612593
申请日：1996-03-08
申请人： Andrew M. Bryant , Nicholas C. Miller , Peter D. Hodson
发明人： Andrew M. Bryant , Nicholas C. Miller , Peter D. Hodson
IPC分类号： B65D83/46 , A61M11/00 , A61M15/00 , B65D83/14 , B65D83/00
CPC分类号： B65D83/425 , A61M15/0091 , A61M15/0095 , B65D83/14 , B65D83/54
摘要： A metered dose dispensing valve is described that is particularly suitable for dispensing metered volumes of a pressurised aerosol formulation. The valve comprises a chamber, and a valve stem extending into the chamber and movable relative to the chamber between non-dispensing and dispensing positions. The valve stem has a configuration and the chamber has an internal configuration such that a metered volume is defined therebetween and such that during movement between its non-dispensing and dispensing positions the valve stem sequentially: (i) allows free flow of aerosol formulation into the chamber, (ii) defines a closed metered volume for pressurised aerosol formulation between the external surface of the valve stem and internal surface of the chamber, and (iii) moves with the closed metered volume within the chamber without decreasing the volume of the closed metered volume until the metered volume communicates with an outlet passage thereby allowing dispensing of the metered volume of pressurised aerosol formulation.
摘要翻译：描述了一种计量剂量分配阀，其特别适用于分配计量体积的加压气溶胶制剂。该阀包括一个腔室和一个延伸到腔室中并可在非分配位置和分配位置之间相对于腔室移动的阀杆。阀杆具有一种构型，并且腔室具有内部结构，使得计量体积在其间限定，使得在其非分配位置和分配位置之间运动时，阀杆顺序地：（i）允许气溶胶制剂自由流入（ii）在阀杆的外表面和腔室的内表面之间限定用于加压气溶胶制剂的闭合计量体积，以及（iii）随着腔室内的闭合计量体积移动，而不减少闭合计量的体积体积直到计量体积与出口通道连通，从而允许分配体积的加压气溶胶制剂。

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