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1. 发明申请

US20160334396A1 BIOMARKER ASSAY USING MICROPARTICLE AGGREGATION 审中-公开
标题翻译：使用微生物聚集的生物标记测定
公开(公告)号：US20160334396A1
公开(公告)日：2016-11-17
申请号：US14855870
申请日：2015-09-16
申请人： Gang CHENG , Jiang Zhe , Yu Han , HaiYan Wu
发明人： Gang CHENG , Jiang Zhe , Yu Han , HaiYan Wu
IPC分类号： G01N33/543 , G01N15/06 , G01N15/02
CPC分类号： G01N33/54326 , G01N15/0227 , G01N15/0266 , G01N15/0656 , G01N15/1031 , G01N15/1056 , G01N15/1459 , G01N15/1463 , G01N15/1484 , G01N33/543 , G01N33/54313 , G01N2015/0065 , G01N2015/0681 , G01N2015/0693 , G01N2015/1006 , G01N2015/1486 , G01N2015/1493
摘要： In various aspects and embodiments, the present invention is directed to versatile, label-free method for the quantitative and qualitative detection of biomarkers and/or other compounds in a fluid sample using functionalized microparticle aggregates. In these methods, micron-scale particles are functionalized to specifically interact with the biomarker being measured and added to the sample to form aggregates, the size and number of which are counted to find a volume fraction and/or number fraction of aggregates in the sample. There is a direct correlation between the volume fraction and number fraction of these aggregates and the concentration of the corresponding biomarker. By comparing the measured volume fraction and/or number fraction of aggregates in the sample to a calibration curve, the concentration of that biomarker may be determined even for biomarkers or other target compounds in samples at very low concentrations, without the need for fluorescence and enzyme labelling of antibodies.
摘要翻译：在各个方面和实施方案中，本发明涉及用于使用官能化的微粒聚集体定量和定性检测流体样品中的生物标志物和/或其它化合物的通用的，无标记的方法。在这些方法中，微米级颗粒被官能化以与被测量的生物标志物特异性相互作用并加入到样品中以形成聚集体，其尺寸和数量被计数以找到样品中的聚集体的体积分数和/或数量分数。这些聚集体的体积分数和数量分数与相应生物标志物的浓度之间存在直接相关性。通过将样品中聚集体的测量体积分数和/或数量分数与校准曲线进行比较，即使对于生物标志物或其它目标化合物，也可以以非常低的浓度测定该生物标志物的浓度，而不需要荧光和酶标记抗体。

2. 发明申请

US20130059200A1 Materials for Battery Electrolytes and Methods for Use 失效
公开(公告)号：US20130059200A1
公开(公告)日：2013-03-07
申请号：US13600192
申请日：2012-08-30
申请人： Vinay V. BHAT , Gang CHENG , Steven S. Kaye , Bin LI , Risa OLUGBILE , Jen-Hsien YANG
发明人： Vinay V. BHAT , Gang CHENG , Steven S. Kaye , Bin LI , Risa OLUGBILE , Jen-Hsien YANG
IPC分类号： H01M10/056
CPC分类号： H01M10/0567 , H01M10/0525 , Y02T10/7011
摘要： Described herein are materials for use in electrolytes that provide a number of desirable characteristics when implemented within batteries, such as high stability during battery cycling up to high temperatures high voltages, high discharge capacity, high coulombic efficiency, and excellent retention of discharge capacity and coulombic efficiency over several cycles of charging and discharging. In some embodiments, a high voltage electrolyte includes a base electrolyte and a set of additive compounds, which impart these desirable performance characteristics.

3. 发明申请

US20120315536A1 Materials for Battery Electrolytes and Methods for Use 审中-公开
公开(公告)号：US20120315536A1
公开(公告)日：2012-12-13
申请号：US13459702
申请日：2012-04-30
申请人： Vinay BHAT , Gang CHENG , Steven KAYE , Bin LI , Risa OLUGBILE , Jen Hsien YANG
发明人： Vinay BHAT , Gang CHENG , Steven KAYE , Bin LI , Risa OLUGBILE , Jen Hsien YANG
IPC分类号： H01M10/056 , H01M6/00
CPC分类号： H01M10/0525 , C07F7/0834 , C07F9/095 , C07F9/098 , C07F9/1415 , H01M10/052 , H01M10/0567 , H01M2300/0025 , Y02T10/7011 , Y10T29/4911
摘要： Described herein are materials for use in electrolytes that provide a number of desirable characteristics when implemented within batteries, such as high stability during battery cycling up to high temperatures high voltages, high discharge capacity, high coulombic efficiency, and excellent retention of discharge capacity and coulombic efficiency over several cycles of charging and discharging. In some embodiments, a high voltage electrolyte includes a base electrolyte and a set of additive compounds, which impart these desirable performance characteristics.

4. 发明申请

US20120328939A1 Materials for Battery Electrolytes and Methods for Use 审中-公开
标题翻译：电池电解质材料和使用方法
公开(公告)号：US20120328939A1
公开(公告)日：2012-12-27
申请号：US13600187
申请日：2012-08-30
申请人： Vinay V. BHAT , Gang CHENG , Steven S. Kaye , Bin LI , Risa OLUGBILE , Jen-Hsien YANG
发明人： Vinay V. BHAT , Gang CHENG , Steven S. Kaye , Bin LI , Risa OLUGBILE , Jen-Hsien YANG
IPC分类号： H01M10/0564
CPC分类号： H01M10/052 , H01M10/0567 , H01M2300/0025 , Y02T10/7011
摘要： Described herein are materials for use in electrolytes that provide a number of desirable characteristics when implemented within batteries, such as high stability during battery cycling up to high temperatures high voltages, high discharge capacity, high coulombic efficiency, and excellent retention of discharge capacity and coulombic efficiency over several cycles of charging and discharging. In some embodiments, a high voltage electrolyte includes a base electrolyte and a set of additive compounds, which impart these desirable performance characteristics.
摘要翻译：这里描述的是用于电解质中的材料，其在电池中实现时提供许多期望的特性，例如在电池循环期间高达高温高电压，高放电容量，高库仑效率以及优异的放电容量保持率和库仑值的高稳定性效率在几个充电和放电循环。在一些实施方案中，高电压电解质包括赋予这些所需性能特征的基础电解质和一组添加剂化合物。

5. 发明申请

US20120315551A1 Materials for Battery Electrolytes and Methods for Use 审中-公开
公开(公告)号：US20120315551A1
公开(公告)日：2012-12-13
申请号：US13459515
申请日：2012-04-30
申请人： Vinay V. BHAT , Gang CHENG , Steven KAYE , Bin LI , Risa OLUGBILE , Jen Hsien YANG
发明人： Vinay V. BHAT , Gang CHENG , Steven KAYE , Bin LI , Risa OLUGBILE , Jen Hsien YANG
IPC分类号： H01M10/056 , H01M10/04
CPC分类号： H01M10/0567 , H01M10/052 , Y02T10/7011 , Y10T29/49108 , Y10T29/4911
摘要： Described herein are materials for use in electrolytes that provide a number of desirable characteristics when implemented within batteries, such as high stability during battery cycling up to high temperatures high voltages, high discharge capacity, high coulombic efficiency, and excellent retention of discharge capacity and coulombic efficiency over several cycles of charging and discharging. In some embodiments, a high voltage electrolyte includes a base electrolyte and a set of additive compounds, which impart these desirable performance characteristics.

6. 发明申请

US20120315534A1 Materials for Battery Electrolytes and Methods for Use 审中-公开
公开(公告)号：US20120315534A1
公开(公告)日：2012-12-13
申请号：US13459734
申请日：2012-04-30
申请人： Vinay BHAT , Gang CHENG , Steven KAYE , Bin LI , Risa OLUGBILE , Jen Hsien YANG
发明人： Vinay BHAT , Gang CHENG , Steven KAYE , Bin LI , Risa OLUGBILE , Jen Hsien YANG
IPC分类号： H01M10/052 , C07F7/10
CPC分类号： H01M10/0525 , C07F7/0834 , C07F9/095 , C07F9/098 , C07F9/1415 , H01M10/052 , H01M10/0567 , H01M2300/0025 , Y02T10/7011 , Y10T29/4911
摘要： Described herein are materials for use in electrolytes that provide a number of desirable characteristics when implemented within batteries, such as high stability during battery cycling up to high temperatures high voltages, high discharge capacity, high coulombic efficiency, and excellent retention of discharge capacity and coulombic efficiency over several cycles of charging and discharging. In some embodiments, a high voltage electrolyte includes a base electrolyte and a set of additive compounds, which impart these desirable performance characteristics.

7. 发明申请

US20180282472A1 METHOD FOR ELECTROPOLYMERIZATION OF HYDROPHILIC EDOT MONOMERS IN AN AQUEOUS SOLUTION 审中-公开
公开(公告)号：US20180282472A1
公开(公告)日：2018-10-04
申请号：US15764049
申请日：2016-09-28
申请人： Gang CHENG
发明人： Gang CHENG
IPC分类号： C08G61/12 , C09D165/00 , H01L51/00 , C09D5/24 , A61L31/10 , C25D9/02
摘要： In one or more embodiments, the present invention provides a method of forming compact, flexible, stable and biocompatible conducting polymer coating for bioelectronics devices. In one or more embodiments, the present invention relates to a novel method of synthesizing a sulfobetaine-functionalized conjugated polymer platform using 3,4-ethylenedioxythiophene (EDOT) as the conducting backbone (SBEDOT). This SBEDOT monomer is highly water-soluble and can be directly polymerized to form a densely packed film/coating on conductive or semi-conductive surfaces through electro-polymerization in a 100% aqueous solution without the need for organic solvents or surfactants. These polySBEDOT (PSBEDOT) coated surfaces have been shown to have electro-switchable antimicrobial/antifouling properties and excellent electrically conducting properties, which minimize infection, increase biocompatibility, and improve the performance of bioelectronics.

8. 发明申请

US20130052542A1 ELECTROLYTE COMPOSITIONS FOR LITHIUM AND LITHIUM-ION BATTERIES 有权
标题翻译：用于锂离子电池和锂离子电池的电解质组合物
公开(公告)号：US20130052542A1
公开(公告)日：2013-02-28
申请号：US13219825
申请日：2011-08-29
申请人： Daniel P. ABRAHAM , Gang CHENG
发明人： Daniel P. ABRAHAM , Gang CHENG
IPC分类号： H01M10/056
CPC分类号： H01M10/0525 , H01M10/0568 , H01M10/0569 , H01M2300/0028 , H01M2300/0037 , Y02E60/122 , Y02T10/7011
摘要： The present invention provides an electrolyte composition for a lithium or lithium-ion battery comprising a lithium salt in a liquid carrier comprising (a) a linear alkyl carbonate solvent, a cyclic alkyl carbonate solvent, or a combination thereof, and (b) a glycerol carbonate derivative compound of Formula (I): wherein X is selected from O, O(CO)O, S, N, P, P(═O), B, and Si; n is 1 when X is O, O(CO)O, or S; n is 2 when x is N, P, P(═O), or B; n is 3 when X is Si; and each R independently is selected from alkyl, alkenyl, alkynyl, aryl, acyl, heteroaryl, a 5-member ring heterocyclic group, a 5-member ring heterocycle-substituted methyl group, trialkylsilyl, and any of the foregoing substituted with one or more fluoro substituents, provided that R is acyl only when X is O, S, or N, and R is not alkyl when X is O(CO)O.
摘要翻译：本发明提供了一种用于锂或锂离子电池的电解质组合物，其在液体载体中包含锂盐，其包含（a）直链烷基碳酸酯溶剂，环状碳酸酯溶剂或其组合，和（b）甘油式（I）的碳酸酯衍生物化合物：其中X选自O，O（CO）O，S，N，P，P（= O），B和Si; 当X为O，O（CO）O或S时，n为1; 当x为N，P，P（= O）或B时，n为2; 当X为Si时，n为3; 并且每个R独立地选自烷基，烯基，炔基，芳基，酰基，杂芳基，5-元环杂环基，5-元环杂环取代的甲基，三烷基甲硅烷基，以及被一个或多个只要X是O，S或N，R仅为酰基，当X是O（CO）O时，R不是烷基。

9. 发明申请

US20120077076A1 HETEROAROMATIC-BASED ELECTROLYTES FOR LITHIUM AND LITHIUM-ION BATTERIES 审中-公开
标题翻译：用于锂离子电池和锂离子电池的基于异氟烷的电解质
公开(公告)号：US20120077076A1
公开(公告)日：2012-03-29
申请号：US12888920
申请日：2010-09-23
申请人： Gang CHENG , Daniel P. ABRAHAM
发明人： Gang CHENG , Daniel P. ABRAHAM
IPC分类号： H01M6/42 , H01M6/16
CPC分类号： H01M10/052 , H01M10/0525 , H01M10/0567 , H01M10/0568 , H01M10/0569 , H01M2300/0028
摘要： The present invention provides an electrolyte for lithium and/or lithium-ion batteries comprising a lithium salt in a liquid carrier comprising heteroaromatic compound including a five-membered or six-membered heteroaromatic ring moiety comprising carbon atoms and at least one heteroatom forming a neutral aromatic ring, the at least one heteroatom being selected from a Group V element (preferably N) and a Group VI element (preferably O or S), the heteroaromatic ring moiety bearing least one carboxylic ester or carboxylic anhydride substituent bound to at least one carbon atom of the heteroaromatic ring. Preferred heteroaromatic ring moieties include pyridine compounds, pyrazine compounds, pyrrole compounds, furan compounds, and thiophene compounds.
摘要翻译：本发明提供了一种用于锂和/或锂离子电池的电解质，其包含液态载体中的锂盐，所述液体载体包括杂芳族化合物，所述杂芳族化合物包括包含碳原子的五元或六元杂芳环部分和至少一个形成中性芳族的杂原子所述至少一个杂原子选自V族元素（优选N）和VI族元素（优选O或S），所述杂芳环部分带有至少一个与至少一个碳原子结合的羧酸酯或羧酸酐取代基的杂芳环。优选的杂芳环部分包括吡啶化合物，吡嗪化合物，吡咯化合物，呋喃化合物和噻吩化合物。

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