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1. 发明授权

US09720063B2 Diffusion spectrum imaging systems and methods 有权
公开(公告)号：US09720063B2
公开(公告)日：2017-08-01
申请号：US13718119
申请日：2012-12-18
申请人： General Electric Company
发明人： Jonathan Immanuel Sperl , Christopher Judson Hardy , Luca Marinelli , Ek Tsoon Tan , Kevin Franklin King , Marion Irene Menzel
IPC分类号： G01R33/563
CPC分类号： G01R33/56341
摘要： Systems and methods for generating a magnetic resonance (MR) image of a tissue are provided. A method includes acquiring MR raw data. The MR raw data corresponds to MR signals obtained at undersampled q-space locations for a plurality of q-space locations that is less than an entirety of the q-space locations and the MR signals at the q-space locations represent the three dimensional displacement distribution of the spins in the imaging voxel. The method also includes performing a joint image reconstruction technique on the MR raw data to exploit structural correlations in the MR signals to obtain a series of accelerated MR images and performing, for each image pixel in each accelerated MR image of the series of accelerated MR images, a compressed sensing reconstruction technique to exploit q-space signal sparsity to identify a plurality of diffusion maps.

2. 发明申请

US20150086096A1 SYSTEMS AND METHODS FOR IMAGE SEGMENTATION USING A DEFORMABLE ATLAS 有权
标题翻译：使用可变图案进行图像分割的系统和方法
公开(公告)号：US20150086096A1
公开(公告)日：2015-03-26
申请号：US14032877
申请日：2013-09-20
申请人： General Electric Company
发明人： Xiaofeng Liu , Albert Montillo , Ek Tsoon Tan , John F. Schenck
IPC分类号： G06T7/00
CPC分类号： G06T7/0089 , G06T7/11 , G06T7/149 , G06T2207/10088 , G06T2207/20128 , G06T2207/30016
摘要： Systems and methods for image segmentation using a deformable atlas are provided. One method includes obtaining one or more target images, obtaining one or more propagated label probabilities for the one or more target images, and segmenting the one or more target images using a cost function of a deformable atlas model. The method further includes identifying segmented structures within the one or more target images based on the segmented one or more target images.
摘要翻译：提供了使用可变形图案的图像分割的系统和方法。一种方法包括获得一个或多个目标图像，为一个或多个目标图像获得一个或多个传播的标签概率，以及使用可变形图集模型的成本函数对一个或多个目标图像进行分割。该方法还包括基于分割的一个或多个目标图像来识别所述一个或多个目标图像内的分段结构。

3. 发明申请

US20140167753A1 DIFFUSION SPECTRUM IMAGING SYSTEMS AND METHODS 有权
标题翻译：扩散光谱成像系统和方法
公开(公告)号：US20140167753A1
公开(公告)日：2014-06-19
申请号：US13718119
申请日：2012-12-18
申请人： GENERAL ELECTRIC COMPANY
发明人： Jonathan Immanuel Sperl , Christopher Judson Hardy , Luca Marinelli , Ek Tsoon Tan , Kevin Franklin King , Marion Irene Menzel
IPC分类号： G01R33/48
CPC分类号： G01R33/56341
摘要： Systems and methods for generating a magnetic resonance (MR) image of a tissue are provided. A method includes acquiring MR raw data. The MR raw data corresponds to MR signals obtained at undersampled q-space locations for a plurality of q-space locations that is less than an entirety of the q-space locations and the MR signals at the q-space locations represent the three dimensional displacement distribution of the spins in the imaging voxel. The method also includes performing a joint image reconstruction technique on the MR raw data to exploit structural correlations in the MR signals to obtain a series of accelerated MR images and performing, for each image pixel in each accelerated MR image of the series of accelerated MR images, a compressed sensing reconstruction technique to exploit q-space signal sparsity to identify a plurality of diffusion maps.
摘要翻译：提供了用于产生组织的磁共振（MR）图像的系统和方法。一种方法包括获取MR原始数据。 MR原始数据对应于在低于q空间位置的整体的多个q空间位置处在欠采样q空间位置处获得的MR信号，并且在q空间位置处的MR信号表示三维位移旋转成像体素的分布。该方法还包括对MR原始数据执行联合图像重建技术以利用MR信号中的结构相关性，以获得一系列加速MR图像，并针对一系列加速MR图像的每个加速MR图像中的每个图像像素执行，一种利用q空间信号稀疏度来识别多个扩散图的压缩感测重建技术。

4. 发明申请

US20210208222A1 LOW ACOUSTIC NOISE MAGNETIC RESONANCE IMAGE ACQUISITION 有权
公开(公告)号：US20210208222A1
公开(公告)日：2021-07-08
申请号：US16735228
申请日：2020-01-06
申请人： General Electric Company
发明人： Christopher Judson Hardy , Thomas Kwok-Fah Foo , Ek Tsoon Tan
IPC分类号： G01R33/385 , G01R33/563 , G01R33/48
摘要： The techniques discussed herein relate to a reduced acoustic noise and vibration magnetic resonance imaging (MRI) acquisition. In certain implementations acoustic noise levels for one or more MRI pulse sequences are characterized and modified by limiting the frequencies and amplitudes of the gradient waveforms so as to produce less noise and vibration when the modified waveform is used during an MRI examination. In this manner, relatively low sound pressure levels can be attained.

5. 发明授权

US09953397B2 System and method for medical image correction 有权
公开(公告)号：US09953397B2
公开(公告)日：2018-04-24
申请号：US14478597
申请日：2014-09-05
申请人： General Electric Company
发明人： Ek Tsoon Tan , Xiaofeng Liu , Dan Xu
IPC分类号： G06K9/00 , A61B5/0436 , G06T3/00 , A61B5/055 , G06T5/00 , G06T7/32
CPC分类号： G06T3/00 , A61B5/055 , G06T5/006 , G06T7/32 , G06T2207/10088
摘要： A method implemented using at least one processor includes receiving a target image and a reference image. The target image is a distorted magnetic resonance image and the reference image is an undistorted magnetic resonance image. The method further includes selecting an image registration method for registering the target image to the reference image, wherein the image registration method uses an image transformation. The method further includes performing image registration of the target image with the reference image, wherein the image registration provides a plurality of optimized parameters of the image transformation. The method also includes generating a corrected image based on the target image and the plurality of optimized parameters of the image transformation.

6. 发明申请

US20170132788A1 SYSTEM AND METHOD FOR ESTIMATING ARTERIAL PULSE WAVE VELOCITY 审中-公开
公开(公告)号：US20170132788A1
公开(公告)日：2017-05-11
申请号：US14936903
申请日：2015-11-10
申请人： General Electric Company
发明人： Prem Venugopal , Thomas Kwok-Fah Foo , Christopher Judson Hardy , Ek Tsoon Tan
IPC分类号： G06T7/00 , A61B5/00 , G06T7/20 , A61B5/026 , A61B5/02 , G06T7/60 , A61B5/055 , A61B5/022
CPC分类号： G06T7/0014 , A61B5/02007 , A61B5/022 , A61B5/026 , A61B5/0285 , A61B5/055 , A61B5/7275 , G06T7/11 , G06T7/62 , G06T2207/10088 , G06T2207/30104 , G16H30/40 , G16H50/30
摘要： A method for determining an arterial pulse wave velocity representative of a health condition of a blood vessel includes receiving an image data set comprising a plurality of images of a subject, from an imaging modality. The method also involves determining a blood vessel region in an image from the plurality of images. The method further includes determining a plurality of cross-sectional area values of a blood vessel at a plurality of locations in the blood vessel region, corresponding to a plurality of phases of a cardiac cycle of the subject and determining a plurality of flow rate values of blood flowing in the blood vessel corresponding to the plurality of cross-sectional area values. The method also includes determining a hemodynamic model based on the plurality of cross-sectional area values and the plurality of blood flow rate values and determining the arterial pulse wave velocity based on the hemodynamic model.

7. 发明申请

US20160054410A1 SYSTEM AND METHOD FOR LOCATING AND QUANTIFYING A BIOMARKER FOR NEUROLOGICAL DISEASE 审中-公开
标题翻译：用于定位和定量生物标记物用于神经病的系统和方法
公开(公告)号：US20160054410A1
公开(公告)日：2016-02-25
申请号：US14826468
申请日：2015-08-14
申请人： GENERAL ELECTRIC COMPANY
发明人： John Frederick Schenck , Ek Tsoon Tan , Dominic Michael Graziani , Suresh Emmanuel Devadoss Joel
IPC分类号： G01R33/48 , G01R33/50 , A61B5/055
CPC分类号： G01R33/50 , A61B5/055 , A61B5/165 , A61B5/4076 , A61B5/4887 , A61B5/4893 , A61B2576/026 , G01R33/5616 , G01R33/56341
摘要： In embodiments of the invention, the habenulae have been identified and localized in normal volunteers. Aspects of the invention determine the location, volume and magnetic susceptibility of the habenulae. Furthermore, diagnosing and monitoring patient disorders are enabled using the herein disclosed methodologies and techniques.
摘要翻译：在本发明的实施方案中，已经在正常志愿者中鉴定和定位了这些。。。本发明的方面确定了h the的位置，体积和磁化率。此外，使用本文公开的方法和技术来实现诊断和监测患者障碍。

8. 发明申请

US20150310640A1 SYSTEMS AND METHODS FOR COMPRESSED SENSING FOR MULTI-SHELL MAGNETIC RESONANCE IMAGING 有权
标题翻译：用于多小波磁共振成像的压缩感测系统和方法
公开(公告)号：US20150310640A1
公开(公告)日：2015-10-29
申请号：US14261623
申请日：2014-04-25
申请人： General Electric Company
发明人： Christopher Judson Hardy , Luca Marinelli , Marion Irene Menzel , Ek Tsoon Tan , Jonathan Immanuel Sperl
IPC分类号： G06T11/00 , G06T7/00
CPC分类号： G06T11/006 , G01R33/4826 , G01R33/5611 , G01R33/56341 , G06T7/0012 , G06T2207/10088 , G06T2207/20056
摘要： A method of compressed sensing for multi-shell magnetic resonance imaging includes obtaining magnetic resonance imaging data, the data being sampled along multi-shell spherical coordinates, the spherical coordinates coincident with a plurality of spokes that converge at an origin, constructing a symmetric shell for each respective sampled multi-shell to create a combined set of data, performing a three-dimensional Fourier transform on the combined set of data to reconstruct an image, and de-noising the reconstructed image by iteratively applying a sparsifying transform on non-sampled data points of neighboring shells. The method can also include randomly under-sampling the imaging data to create missing data points. A system configured to implement the method and a non-transitory computer readable medium are also disclosed.
摘要翻译：一种用于多壳磁共振成像的压缩感测方法包括：获得磁共振成像数据，所述数据沿着多壳球面坐标进行采样，所述球面坐标与在原点收敛的多个辐条重合，构成对称壳体每个相应的采样多壳以产生一组组合数据，对该组合数据进行三维傅里叶变换以重构图像，并通过对非采样数据迭代地应用稀疏变换来对重构图像进行去噪相邻炮弹点。该方法还可以包括随机对取样数据进行低采样以创建丢失的数据点。还公开了一种被配置为实现该方法的系统和一种非暂时计算机可读介质。

9. 发明申请

US20200132792A1 RADIOFREQUENCY COIL AND SHIELD IN MAGNETIC RESONANCE IMAGING METHOD AND APPRARATUS 审中-公开
公开(公告)号：US20200132792A1
公开(公告)日：2020-04-30
申请号：US16169536
申请日：2018-10-24
申请人： General Electric Company
发明人： Mark Ernest Vermilyea , Justin Michael Ricci , Christina Vasil , Ek Tsoon Tan , Eric William Fiveland , Yihe Hua , Thomas Kwok-Fah Foo
IPC分类号： G01R33/422 , G01R33/385 , G01R33/34 , A61B5/055
摘要： An imaging device may include a patient bore to house a subject to be imaged, wherein the patient bore includes one or more bore tubes. The imaging device may also include a gradient coil surrounding, at least partially, the patient bore and a radio frequency (RF) shield located outside the one or more bore tubes. Additionally, the imaging device may include an RF coil located within at least one of the bore tubes.

10. 发明授权

US10438355B2 System and method for estimating arterial pulse wave velocity 有权
公开(公告)号：US10438355B2
公开(公告)日：2019-10-08
申请号：US14936903
申请日：2015-11-10
申请人： General Electric Company
发明人： Prem Venugopal , Thomas Kwok-Fah Foo , Christopher Judson Hardy , Ek Tsoon Tan
IPC分类号： A61B6/00 , G06T7/00 , A61B5/02 , A61B5/022 , A61B5/026 , A61B5/055 , A61B5/00 , A61B5/0285 , G06T7/11 , G06T7/62 , G16H50/30 , G16H30/40
摘要： A method for determining an arterial pulse wave velocity representative of a health condition of a blood vessel includes receiving an image data set comprising a plurality of images of a subject, from an imaging modality. The method also involves determining a blood vessel region in an image from the plurality of images. The method further includes determining a plurality of cross-sectional area values of a blood vessel at a plurality of locations in the blood vessel region, corresponding to a plurality of phases of a cardiac cycle of the subject and determining a plurality of flow rate values of blood flowing in the blood vessel corresponding to the plurality of cross-sectional area values. The method also includes determining a hemodynamic model based on the plurality of cross-sectional area values and the plurality of blood flow rate values and determining the arterial pulse wave velocity based on the hemodynamic model.

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