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1. 发明授权

US08469919B2 Apparatus and methods for uniformly distributing coolant within a cryo-ablation device 有权
标题翻译：在冷冻消融装置内均匀分配冷却剂的装置和方法
公开(公告)号：US08469919B2
公开(公告)日：2013-06-25
申请号：US12388399
申请日：2009-02-18
申请人： Frank Ingle , Raphael Hon
发明人： Frank Ingle , Raphael Hon
IPC分类号： A61B18/18
CPC分类号： A61B18/02 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262
摘要： Apparatus and methods for uniformly distributing coolant within a cryo-ablation device. A nozzle apparatus includes a tubular member having a plurality of angled apertures that induce swirling of coolant streams dispersed through the angled apertures. Coolant swirling round the tubular member and along an inner surface of an inflatable balloon element inflates the balloon element and cryogenically ablate tissue. The swirling action achieved using angled apertures uniformly distributes coolant along the inner surface of the balloon such that the temperatures along an inner surface of the balloon element and ablation of tissue adjacent to the balloon element are substantially uniform.
摘要翻译：在冷冻消融装置内均匀分配冷却剂的装置和方法。喷嘴装置包括管状构件，其具有多个成角度的孔，其引导分散通过倾斜孔的冷却剂流的旋转。冷却液在管状构件周围旋转并且沿着可充气球囊元件的内表面膨胀，从而使球囊元件膨胀并且低温地烧蚀组织。使用角度孔使得的旋转动作沿着球囊的内表面均匀地分布冷却剂，使得沿着球囊元件的内表面的温度和与球囊元件相邻的组织的消融基本上是均匀的。

2. 发明申请

US20090209949A1 APPARATUS AND METHODS FOR UNIFORMLY DISTRIBUTING COOLANT WITHIN A CRYO-ABLATION DEVICE 有权
标题翻译：装置和方法，用于在皱纹装置中均匀分配冷却剂
公开(公告)号：US20090209949A1
公开(公告)日：2009-08-20
申请号：US12388399
申请日：2009-02-18
申请人： Frank Ingle , Raphael Hon
发明人： Frank Ingle , Raphael Hon
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262
摘要： Apparatus and methods for uniformly distributing coolant within a cryo-ablation device. A nozzle apparatus includes a tubular member having a plurality of angled apertures that induce swirling of coolant streams dispersed through the angled apertures. Coolant swirling round the tubular member and along an inner surface of an inflatable balloon element inflates the balloon element and cryogenically ablate tissue. The swirling action achieved using angled apertures uniformly distributes coolant along the inner surface of the balloon such that the temperatures along an inner surface of the balloon element and ablation of tissue adjacent to the balloon element are substantially uniform.
摘要翻译：在冷冻消融装置内均匀分配冷却剂的装置和方法。喷嘴装置包括管状构件，其具有多个成角度的孔，其引导分散通过倾斜孔的冷却剂流的旋转。冷却液在管状构件周围旋转并且沿着可充气球囊元件的内表面膨胀，从而使球囊元件膨胀并且低温地烧蚀组织。使用角度孔使得的旋转动作沿着球囊的内表面均匀地分布冷却剂，使得沿着球囊元件的内表面的温度和与球囊元件相邻的组织的消融基本上是均匀的。

3. 发明授权

US09309860B2 Wave energy conversion device 有权
标题翻译：波能量转换装置
公开(公告)号：US09309860B2
公开(公告)日：2016-04-12
申请号：US13508347
申请日：2010-11-04
申请人： Raphael Hon
发明人： Raphael Hon
IPC分类号： F03B13/18 , F03B13/12 , F03B13/16 , F03B13/20 , F03B13/24 , B63B35/44
CPC分类号： F03B13/1815 , B63B2035/4466 , F03B13/12 , F03B13/16 , F03B13/18 , F03B13/1805 , F03B13/181 , F03B13/186 , F03B13/20 , F03B13/24 , F05B2210/404 , F05B2240/40 , F05B2240/93 , F05B2240/95 , F05B2250/411 , F05B2260/4021 , F05B2260/4031 , Y02E10/20 , Y02E10/32 , Y02E10/38
摘要： Several embodiments of a device for economically harvesting wave energy are disclosed. A sealed vessel for air storage, the spar buoy, is mostly submerged under water is also used as an inertial body that surface floats move relative to. The spar buoy may take many geometrical forms, but all have a stem that is above the water surface. Piston pumps are placed at the top of the stem. The pump has a gearing reduction to optimize the rotational motion of the pump drive shaft. Small angular motion at the drive shaft results in multiple cycles of linear reciprocal motion of the piston. Various mechanisms could convert the relative motion between the floats and the spar buoy to a rotational motion of the shaft. The compressed air generated by the pump is stored in the spar buoy and regenerated as electrical energy by expanding the compressed air in a turbine.
摘要翻译：公开了用于经济地收获波能的装置的几个实施例。用于空气储存的密封容器，翼梁浮标主要被淹没在水下，也用作表面浮动相对的惯性体。翼梁浮标可能具有许多几何形状，但都具有位于水面之上的杆。活塞泵位于阀杆顶部。泵具有齿轮减速以优化泵驱动轴的旋转运动。驱动轴处的小角度运动导致活塞的线性往复运动的多个循环。各种机构可以将浮子和翼梁浮标之间的相对运动转换成轴的旋转运动。由泵产生的压缩空气被储存在翼梁浮标中，并通过在涡轮机中膨胀压缩空气而再生为电能。

4. 发明授权

US09028445B2 Apparatus and method for chilling cryo-ablation coolant and resulting cryo-ablation system 有权
标题翻译：用于冷冻冷冻消融冷却剂和产生的冷冻消融系统的装置和方法
公开(公告)号：US09028445B2
公开(公告)日：2015-05-12
申请号：US12432465
申请日：2009-04-29
申请人： Frank W. Ingle , Leonard George , Raphael Hon , Joann Heberer
发明人： Frank W. Ingle , Leonard George , Raphael Hon , Joann Heberer
IPC分类号： A61F7/12 , A61B18/02 , A61B17/22 , A61B18/00
CPC分类号： A61B18/02 , A61B2017/22051 , A61B2018/00166 , A61B2018/00172 , A61B2018/0022 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262
摘要： Apparatus and methods for cooling liquid coolant, such as nitrous oxide, to be delivered to a cryo-ablation device such as a balloon catheter. A hose or conduit in fluid communication with the ablation device includes an outer member and inner tubes. A first inner tube disposed within a lumen of the outer member carries liquid coolant to the ablation device. Another inner tube also disposed within the lumen carries liquid coolant and terminates within the lumen such that gaseous coolant derived from liquid coolant flowing through the second inner tube flows within the lumen to cool or chill the first inner tube and liquid coolant carried by the first inner tube to the ablation device.
摘要翻译：用于冷却诸如一氧化二氮的液体冷却剂的装置和方法将被输送到诸如球囊导管的低温消融装置。与消融装置流体连通的软管或导管包括外部构件和内部管。设置在外部构件的内腔内的第一内管将液体冷却剂携带到消融装置。还设置在内腔内的另一内管承载液体冷却剂并且终止在内腔内，使得源自流过第二内管的液体冷却剂的气态冷却剂在管腔内流动以冷却或冷却第一内管和由第一内管管到消融装置。

5. 发明申请

US20130008158A1 Wave Energy Conversion Device 有权
标题翻译：波能量转换装置
公开(公告)号：US20130008158A1
公开(公告)日：2013-01-10
申请号：US13508347
申请日：2010-11-04
申请人： Raphael Hon
发明人： Raphael Hon
IPC分类号： F03B13/18
CPC分类号： F03B13/1815 , B63B2035/4466 , F03B13/12 , F03B13/16 , F03B13/18 , F03B13/1805 , F03B13/181 , F03B13/186 , F03B13/20 , F03B13/24 , F05B2210/404 , F05B2240/40 , F05B2240/93 , F05B2240/95 , F05B2250/411 , F05B2260/4021 , F05B2260/4031 , Y02E10/20 , Y02E10/32 , Y02E10/38
摘要： Several embodiments of a device for economically harvesting wave energy are disclosed. A sealed vessel for air storage, the spar buoy, is mostly submerged under water is also used as an inertial body that surface floats move relative to. The spar buoy may take many geometrical forms, but all have a stem that is above the water surface. Piston pumps are placed at the top of the stem. The pump has a gearing reduction to optimize the rotational motion of the pump drive shaft. Small angular motion at the drive shaft results in multiple cycles of linear reciprocal motion of the piston. Various mechanisms could convert the relative motion between the floats and the spar buoy to a rotational motion of the shaft. The compressed air generated by the pump is stored in the spar buoy and regenerated as electrical energy by expanding the compressed air in a turbine.
摘要翻译：公开了用于经济地收获波能的装置的几个实施例。用于空气储存的密封容器，翼梁浮标主要被淹没在水下，也用作表面浮动相对的惯性体。翼梁浮标可能具有许多几何形状，但都具有位于水面之上的杆。活塞泵位于阀杆顶部。泵具有齿轮减速以优化泵驱动轴的旋转运动。驱动轴处的小角度运动导致活塞的线性往复运动的多个循环。各种机构可以将浮子和翼梁浮标之间的相对运动转换成轴的旋转运动。由泵产生的压缩空气被储存在翼梁浮标中，并通过在涡轮机中膨胀压缩空气而再生为电能。

6. 发明申请

US20090171333A1 SYSTEM AND METHOD FOR CONTROLLABLY DELIVERING LIQUID COOLANT TO A CRYO-ABLATION DEVICE 审中-公开
标题翻译：用于控制将液体冷却剂递送到CRYO-ABLATION设备的系统和方法
公开(公告)号：US20090171333A1
公开(公告)日：2009-07-02
申请号：US12334215
申请日：2008-12-12
申请人： Raphael Hon
发明人： Raphael Hon
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2018/0212 , A61B2018/0262
摘要： Systems and methods for controllably delivering liquid coolant such as nitrous oxide to an ablation device for cryogenically ablating tissue. A cooling element liquefies gaseous coolant released from a coolant supply or tank. An actuator in fluid communication with and between the cooling element and the ablation device defines a chamber. Liquid coolant is controllably drawn into and controllably expelled from the chamber for delivery to the cryo-ablation device. Liquid coolant can be controllably drawn into the chamber from the cooling element or from a container or reservoir that stores liquid coolant generated by the cooling element.
摘要翻译：用于可控地将诸如一氧化二氮的液体冷却剂输送到用于低温消融组织的消融装置的系统和方法。冷却元件液化从冷却剂供应源或罐排出的气态冷却剂。与冷却元件和消融装置流体连通的致动器限定了腔室。液体冷却剂被可控地吸入并可控制地从腔室排出以输送到冷冻消融装置。液体冷却剂可以从冷却元件或储存由冷却元件产生的液体冷却剂的容器或贮存器可控制地吸入室内。

7. 发明申请

US20090281533A1 APPARATUS AND METHOD FOR CHILLING CRYO-ABLATION COOLANT AND RESULTING CRYO-ABLATION SYSTEM 有权
标题翻译：冷冻消融冷却剂和结晶洗涤系统的设备和方法
公开(公告)号：US20090281533A1
公开(公告)日：2009-11-12
申请号：US12432465
申请日：2009-04-29
申请人： Frank W. Ingle , Leonard George , Raphael Hon , Joann Heberer
发明人： Frank W. Ingle , Leonard George , Raphael Hon , Joann Heberer
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/22051 , A61B2018/00166 , A61B2018/00172 , A61B2018/0022 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262
摘要： Apparatus and methods for cooling liquid coolant, such as nitrous oxide, to be delivered to a cryo-ablation device such as a balloon catheter. A hose or conduit in fluid communication with the ablation device includes an outer member and inner tubes. A first inner tube disposed within a lumen of the outer member carries liquid coolant to the ablation device. Another inner tube also disposed within the lumen carries liquid coolant and terminates within the lumen such that gaseous coolant derived from liquid coolant flowing through the second inner tube flows within the lumen to cool or chill the first inner tube and liquid coolant carried by the first inner tube to the ablation device.
摘要翻译：用于冷却诸如一氧化二氮的液体冷却剂的装置和方法将被输送到诸如球囊导管的低温消融装置。与消融装置流体连通的软管或导管包括外部构件和内部管。设置在外部构件的内腔内的第一内管将液体冷却剂携带到消融装置。还设置在内腔内的另一内管承载液体冷却剂并且终止在内腔内，使得源自流过第二内管的液体冷却剂的气态冷却剂在管腔内流动以冷却或冷却第一内管和由第一内管管到消融装置。

8. 发明授权

US10076213B1 Kitchen implements for separating lipids from food 有权
公开(公告)号：US10076213B1
公开(公告)日：2018-09-18
申请号：US15836751
申请日：2017-12-08
申请人： Raphael Hon
发明人： Raphael Hon
IPC分类号： A47J43/28
CPC分类号： A47J43/285 , A47J43/28 , A47J43/286
摘要： A kitchen utensil for removing lipids from food includes a handle having a first end, a second end, and a gripping region between the first end and the second end, a head extending from the second end of the handle, the head having first side, a second side, and an outer perimeter, and wherein the first side includes at least one groove extending inwardly from a first groove end located at the outer perimeter, the at least one groove configured to collect a lipid material therein.

9. 发明授权

US08579890B2 Cryo-ablation refrigerant distribution catheter 有权
标题翻译：冷冻消融制冷剂分配导管
公开(公告)号：US08579890B2
公开(公告)日：2013-11-12
申请号：US12402970
申请日：2009-03-12
申请人： Raphael Hon
发明人： Raphael Hon
IPC分类号： A61B18/18 , A61M37/00
CPC分类号： A61B18/02 , A61B2017/22051 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262
摘要： Described herein are methods and devices for performing ablation via a cryoablation catheter. An ablation catheter having a cyroablation chamber at its distal end can be used to achieve a uniform ablation band in or around the pulmonary veins. The cyrochamber can house a dispersion member in fluid communication with a refrigerant supply and can function to evenly distribute received refrigerant over some portion of the inner wall of the cryochamber. As a result of this even distribution of refrigerant within the cyrochamber, uniform ablation of the targeted tissue of the patient can be achieved.
摘要翻译：这里描述的是通过冷冻消融导管进行消融的方法和装置。可以使用在其远端具有排除腔的消融导管来实现肺静脉内或周围的均匀消融带。电解槽可以容纳与制冷剂供应流体连通的分散构件，并且可以起作用以将接收的制冷剂均匀地分布在冷冻箱的内壁的某一部分上。由于这种均匀分布在细胞腔内的制冷剂，可以实现患者目标组织的均匀消融。

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