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1. 发明授权

US08074229B2 Co-execution of objects from divergent runtime environments 有权
标题翻译：从不同的运行时环境共同执行对象
公开(公告)号：US08074229B2
公开(公告)日：2011-12-06
申请号：US11880050
申请日：2007-07-18
申请人： Frank Brunswig , Jan Heiler , Martin Helm , Wolfgang Nieswand , Joerg Rosbach
发明人： Frank Brunswig , Jan Heiler , Martin Helm , Wolfgang Nieswand , Joerg Rosbach
IPC分类号： G06F3/00 , G06F9/44 , G06F9/46 , G06F13/00
CPC分类号： G06F9/544 , G06F9/455 , G06F9/541
摘要： Systems and methods are described that permit objects from runtime environments that are incompatible with one another to be co-executed on a computing machine. Depending on which object can service the request, a generic proxy may send the request to the proxy of the particular runtime environment associated with that object. The proxy may call the appropriate methods of the object therein to service the request. Each runtime environment may be isolated from other runtime environments by a container such that catastrophic errors in one runtime environment do not disrupt the execution of objects in another runtime environment. A first object in a first runtime environment may execute methods in a second object in a second runtime environment by invoking a proxy of the second runtime environment to call the methods of the second object.
摘要翻译：描述了允许彼此不兼容的运行时环境的对象在计算机上共同执行的系统和方法。根据哪个对象可以对请求进行服务，通用代理可以将请求发送到与该对象相关联的特定运行时环境的代理。代理可以调用其中的对象的适当方法来服务请求。每个运行时环境可以通过容器与其他运行时环境隔离，使得一个运行时环境中的灾难性错误不会中断另一运行时环境中对象的执行。第一运行时环境中的第一对象可以通过调用第二运行时环境的代理来调用第二对象的方法来在第二运行时环境中的第二对象中执行方法。

2. 发明申请

US20090025009A1 Co-execution of objects from divergent runtime environments 有权
标题翻译：从不同的运行时环境共同执行对象
公开(公告)号：US20090025009A1
公开(公告)日：2009-01-22
申请号：US11880050
申请日：2007-07-18
申请人： Frank Brunswig , Jan Heiler , Martin Helm , Wolfgang Nieswand , Joerg Rosbach
发明人： Frank Brunswig , Jan Heiler , Martin Helm , Wolfgang Nieswand , Joerg Rosbach
IPC分类号： G06F9/46
CPC分类号： G06F9/544 , G06F9/455 , G06F9/541
摘要： Systems and methods are described that permit objects from runtime environments that are incompatible with one another to be co-executed on a computing machine. Depending on which object can service the request, a generic proxy may send the request to the proxy of the particular runtime environment associated with that object. The proxy may call the appropriate methods of the object therein to service the request. Each runtime environment may be isolated from other runtime environments by a container such that catastrophic errors in one runtime environment do not disrupt the execution of objects in another runtime environment. A first object in a first runtime environment may execute methods in a second object in a second runtime environment by invoking a proxy of the second runtime environment to call the methods of the second object.
摘要翻译：描述了允许彼此不兼容的运行时环境的对象在计算机上共同执行的系统和方法。根据哪个对象可以对请求进行服务，通用代理可以将请求发送到与该对象相关联的特定运行时环境的代理。代理可以调用其中的对象的适当方法来服务请求。每个运行时环境可以通过容器与其他运行时环境隔离，使得一个运行时环境中的灾难性错误不会中断另一运行时环境中对象的执行。第一运行时环境中的第一对象可以通过调用第二运行时环境的代理来调用第二对象的方法来在第二运行时环境中的第二对象中执行方法。

3. 发明申请

US20120030666A1 STANDARDIZED PROCEDURES FOR IMPLEMENTING SOFTWARE CHANGES 有权
标题翻译：执行软件更改的标准化程序
公开(公告)号：US20120030666A1
公开(公告)日：2012-02-02
申请号：US12848011
申请日：2010-07-30
申请人： Karolin Laicher , Martin Helm
发明人： Karolin Laicher , Martin Helm
IPC分类号： G06F9/44
CPC分类号： G06F8/65
摘要： A change to a tenant-independent content item identified as a target for changes as part of an update process of a core software platform provided by a multi-tenant system can be registered, and one or more customer tenants of the multi-tenant system can be analyzed to identify tenant-specific content items to which the registered change are relevant. A sequence can be established for processing a modification to the tenant-specific content item resulting from the registered change. The sequence can be based on at least one dependency of the tenant-specific content item on the tenant-independent content item affected by the registered change. Related articles and systems are also disclosed.
摘要翻译：可以注册对作为多租户系统提供的核心软件平台的更新过程的一部分而被识别为作为变更的目标的与租户无关的内容项目的改变，并且多租户系统的一个或多个客户租户可以被分析以识别注册的变更相关的特定于租户的内容项目。可以建立一个序列来处理由注册的变化产生的对特定于租户的内容项的修改。该序列可以基于受注册变化影响的与承租人无关的内容项目上的租户特定内容项目的至少一个依赖性。还公开了相关文章和系统。

4. 发明授权

US07807437B2 Variants of hepatitis B virus resistant against some nucleoside analogues, but sensitive to others, and uses thereof 有权
标题翻译：乙型肝炎病毒对某些核苷类似物具有抗性但对其他人敏感的变体及其用途
公开(公告)号：US07807437B2
公开(公告)日：2010-10-05
申请号：US11375580
申请日：2006-03-15
申请人： Oliver Schildgen , Martin Vogel , Bertfried Matz , Juergen Rockstroh , Rolf Kaiser , Martin Daeumer , Martin Helm , Lutwin Weitner , Carl Knud Schewe , Wolfram Gerlich
发明人： Oliver Schildgen , Martin Vogel , Bertfried Matz , Juergen Rockstroh , Rolf Kaiser , Martin Daeumer , Martin Helm , Lutwin Weitner , Carl Knud Schewe , Wolfram Gerlich
IPC分类号： C12N7/00
CPC分类号： C12N7/00 , C07K14/005 , C12N9/1276 , C12N2730/10121 , C12N2730/10122 , C12Q1/706 , C12Q2600/156 , G01N33/5761 , G01N2333/02
摘要： The present invention relates generally to the field of Hepatitis B variants exhibiting a reduced sensitivity to nucleoside analogues both in vivo and in vitro. More in particular, reverse transcriptase mutant rt I233V is provided. Present invention provides assays and methods for detecting such variant, which assays are useful in monitoring anti-viral therapeutic regimes and adjusting patient therapy. A diagnostic kit for detecting the presence of an HBV variant in a biological sample has also been described. Finally, the use of a pharmaceutical composition to cure a subject suffering from a HBV infection, which HBV is resistant to lamuvidine and/or adefovir has been provided, which pharmaceutical composition comprises the nucleoside analogue tenofovir.
摘要翻译：本发明一般涉及在体内和体外对核苷类似物的敏感性降低的乙型肝炎变体领域。更具体地，提供逆转录酶突变体rt I233V。本发明提供了用于检测这种变体的测定和方法，该测定法可用于监测抗病毒治疗方案并调整患者治疗。还描述了用于检测生物样品中HBV变异体的存在的诊断试剂盒。最后，已经提供了使用药物组合物治疗HBV感染的受试者，其HBV对lamvvidine和/或阿德福韦有抗性，该药物组合物包含核苷类似物替诺福韦。

5. 发明申请

US20050283423A1 System and method for updating stop loss orders 有权
标题翻译：更新止损订单的系统和方法
公开(公告)号：US20050283423A1
公开(公告)日：2005-12-22
申请号：US10869899
申请日：2004-06-18
申请人： Martin Moser , Martin Helm , Uwe Riss , Bernd Maier , Ali Becerikogullari , Uwe Bischoff
发明人： Martin Moser , Martin Helm , Uwe Riss , Bernd Maier , Ali Becerikogullari , Uwe Bischoff
IPC分类号： G06Q40/00 , G06F17/60
CPC分类号： G06Q40/06 , G06Q40/00 , G06Q40/04
摘要： A method and system are disclosed for automatically updating individual conditions associated with a pending conditional financial transaction. As the price of a financial instrument varies, a pending conditional financial transaction may be issued to cause the financial instrument to be bought or sold whenever its price satisfies certain specified conditions. In the field of common stock transactions, the disclosed method automatically updates a pending conditional sell order, called a stop loss order, upon the occurrence of several conditions, such as when the current stop loss order has expired, when the current price of one share of the stock has risen a predetermined percentage above the current stop loss value, or when the total value of all of the shares of the stock has increased beyond a predetermined percentage limit. When a stop loss order is updated, a new stop loss value is calculated based upon the current price and a percentage leeway in the price. The new stop loss order is then transmitted to an appropriate financial institution
摘要翻译：公开了用于自动更新与待决条件金融交易相关联的个别条件的方法和系统。随着金融工具的价格变化，可以发行待定的有条件金融交易，以使其在价格满足某些特定条件时进行买卖。在普通股交易领域中，所公开的方法在发生若干条件时，例如当当前止损订单已经到期时，自动更新挂牌有条件卖单，称为止损单，当一个股份的当前价格的股票已经超过当前止损价值的预定百分比，或者股票全部股份的总价值已经超过预定的百分比。当止损单更新时，将根据当前价格和价格中的百分比余数计算新的止损值。然后将新的止损单转交给适当的金融机构

6. 发明授权

US08392908B2 Standardized procedures for implementing software changes 有权
标题翻译：执行软件更改的标准化程序
公开(公告)号：US08392908B2
公开(公告)日：2013-03-05
申请号：US12848011
申请日：2010-07-30
申请人： Karolin Laicher , Martin Helm
发明人： Karolin Laicher , Martin Helm
IPC分类号： G06F9/445
CPC分类号： G06F8/65
摘要： A change to a tenant-independent content item identified as a target for changes as part of an update process of a core software platform provided by a multi-tenant system can be registered, and one or more customer tenants of the multi-tenant system can be analyzed to identify tenant-specific content items to which the registered change are relevant. A sequence can be established for processing a modification to the tenant-specific content item resulting from the registered change. The sequence can be based on at least one dependency of the tenant -specific content item on the tenant-independent content item affected by the registered change. Related articles and systems are also disclosed.
摘要翻译：可以注册对作为多租户系统提供的核心软件平台的更新过程的一部分而被识别为作为变更的目标的与租户无关的内容项目的改变，并且多租户系统的一个或多个客户租户可以被分析以识别注册的变更相关的特定于租户的内容项目。可以建立一个序列来处理由注册的变化产生的对特定于租户的内容项的修改。该序列可以基于租户特定内容项目对受注册变化影响的与租户无关的内容项目的至少一个依赖性。还公开了相关文章和系统。

7. 发明授权

US07555449B2 System and method for updating stop loss orders 有权
标题翻译：更新止损订单的系统和方法
公开(公告)号：US07555449B2
公开(公告)日：2009-06-30
申请号：US10869899
申请日：2004-06-18
申请人： Martin Moser , Martin Helm , Uwe Riss , Bernd Maier , Ali Becerikogullari , Uwe Bischoff
发明人： Martin Moser , Martin Helm , Uwe Riss , Bernd Maier , Ali Becerikogullari , Uwe Bischoff
IPC分类号： G06Q40/00
CPC分类号： G06Q40/06 , G06Q40/00 , G06Q40/04
摘要： A method and system are disclosed for automatically updating individual conditions associated with a pending conditional financial transaction. As the price of a financial instrument varies, a pending conditional financial transaction may be issued to cause the financial instrument to be bought or sold whenever its price satisfies certain specified conditions. In the field of common stock transactions, the disclosed method automatically updates a pending conditional sell order, called a stop loss order, upon the occurrence of several conditions, such as when the current stop loss order has expired, when the current price of one share of the stock has risen a predetermined percentage above the current stop loss value, or when the total value of all of the shares of the stock has increased beyond a predetermined percentage limit. When a stop loss order is updated, a new stop loss value is calculated based upon the current price and a percentage leeway in the price. The new stop loss order is then transmitted to an appropriate financial institution.
摘要翻译：公开了用于自动更新与待决条件金融交易相关联的个别条件的方法和系统。随着金融工具的价格变化，可以发行待定的有条件金融交易，以使其在价格满足某些特定条件时进行买卖。在普通股交易领域中，所公开的方法在发生若干条件时，例如当当前止损订单已经到期时，自动更新挂牌有条件卖单，称为止损单，当期一股的价格的股票已经超过当前止损价值的预定百分比，或者股票全部股份的总价值已经超过预定的百分比。当止损单更新时，将根据当前价格和价格中的百分比余数计算新的止损值。然后将新的止损单转交给适当的金融机构。

8. 发明申请

US20070042356A1 Variants of hepatitis B virus resistant against some nucleoside analogues, but sensitive to others, and uses thereof 有权
标题翻译：乙型肝炎病毒对某些核苷类似物具有抗性但对其他人敏感的变体及其用途
公开(公告)号：US20070042356A1
公开(公告)日：2007-02-22
申请号：US11375580
申请日：2006-03-15
申请人： Oliver Schildgen , Martin Vogel , Bertfried Matz , Juergen Rockstroh , Rolf Kaiser , Martin Daeumer , Martin Helm , Lutwin Weitner , Carl Schewe , Wolfram Gerlich
发明人： Oliver Schildgen , Martin Vogel , Bertfried Matz , Juergen Rockstroh , Rolf Kaiser , Martin Daeumer , Martin Helm , Lutwin Weitner , Carl Schewe , Wolfram Gerlich
IPC分类号： C12Q1/70 , C07H21/04 , A61K31/7072 , C07K14/02 , C12N15/86 , C12N7/01
CPC分类号： C12N7/00 , C07K14/005 , C12N9/1276 , C12N2730/10121 , C12N2730/10122 , C12Q1/706 , C12Q2600/156 , G01N33/5761 , G01N2333/02
摘要： The present invention relates generally to the field of Hepatitis B variants exhibiting a reduced sensitivity to nucleoside analogues both in vivo and in vitro. More in particular, reverse transcriptase mutant rt I233V is provided. Present invention provides assays and methods for detecting such variant, which assays are useful in monitoring anti-viral therapeutic regimes and adjusting patient therapy. A diagnostic kit for detecting the presence of an HBV variant in a biological sample has also been described. Finally, the use of a farmaceutical composition to cure a subject suffering from a HBV infection, which HBV is resistant to lamuvidine and/or adefovir has been provided, which farmaceutical composition comprises the nucleoside analogue tenofovir.
摘要翻译：本发明一般涉及在体内和体外对核苷类似物的敏感性降低的乙型肝炎变体领域。更具体地，提供逆转录酶突变体rt I233V。本发明提供了用于检测这种变体的测定和方法，该测定法可用于监测抗病毒治疗方案并调整患者治疗。还描述了用于检测生物样品中HBV变异体的存在的诊断试剂盒。最后，提供了一种药物组合物治疗患有HBV感染的受试者，其HBV对lamvvidine和/或阿德福韦具有抗性，该药物组合物包含核苷类似物替诺福韦。

9. 发明申请

US20060143227A1 System and method for persisting software objects 审中-公开
标题翻译：持久化软件对象的系统和方法
公开(公告)号：US20060143227A1
公开(公告)日：2006-06-29
申请号：US11023917
申请日：2004-12-27
申请人： Martin Helm , Martin Moser , Bernd Maier
发明人： Martin Helm , Martin Moser , Bernd Maier
IPC分类号： G06F7/00
CPC分类号： G06F9/4493
摘要： Embodiments of the invention are generally directed to a system and method for persisting software objects. In an embodiment, objects are scanned with object introspection to identify the members of the object. The members are transformed into an intermediate data structure. The scan and transformation process can be influenced with configurable rules. If the object references another object, then the process is repeated recursively on the other object. Thus, in an embodiment, an entire object closure may be scanned and transformed into the intermediate data structure. The intermediate data structure is persisted in a data store.
摘要翻译：本发明的实施例通常涉及用于持久化软件对象的系统和方法。在一个实施例中，用对象反省来扫描对象以识别对象的成员。成员被转换成中间数据结构。扫描和转换过程可能受到可配置规则的影响。如果对象引用另一个对象，那么该过程在另一个对象上递归地重复。因此，在一个实施例中，整个对象闭合可被扫描并转换成中间数据结构。中间数据结构保存在数据存储中。

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