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1. 发明授权

US5047434A Method for weight gain-increasing of fodder utilization of pigs, cattle or poultry 失效
标题翻译：饲养猪，牛或家禽饲料利用增重的方法
公开(公告)号：US5047434A
公开(公告)日：1991-09-10
申请号：US375507
申请日：1989-07-05
申请人： Ferenc Simon , Karoly Magyar , Attila Nagy , Lajos Fekete , Laszlo Puskas , Pal Fekete , Istvan Simonyi , Janos Egri , Katalin Zukovics nee Sumeg
发明人： Ferenc Simon , Karoly Magyar , Attila Nagy , Lajos Fekete , Laszlo Puskas , Pal Fekete , Istvan Simonyi , Janos Egri , Katalin Zukovics nee Sumeg
IPC分类号： A23K1/16 , A61K31/135 , A61P3/00 , C07C215/56
CPC分类号： A61K31/135
摘要： The invention relates to weight gain-increasing compositions, particularly fodder supplement, premix, drinking water supplement, bolus and/or microcapsule containing 0.001 to 90% by weight of 1-(3,5-dihydroxyphenyl)-2-(tertiary butylamino)-ethanol or a physiologically acceptable acid addition salt thereof as active ingredient in admixture with inert solid and/or liquid carrier(s).
摘要翻译：本发明涉及增重组合物，特别是饲料补充剂，预混物，饮用水补充剂，推注和/或含有0.001至90重量％的1-（3,5-二羟基苯基）-2-（叔丁基氨基） - 乙醇或其生理上可接受的酸加成盐作为活性成分与惰性固体和/或液体载体混合。

2. 发明授权

US5120711A Synergistically active veterinary compositions and process for preparing same 失效
标题翻译：合成活性兽药组合物及其制备方法
公开(公告)号：US5120711A
公开(公告)日：1992-06-09
申请号：US616813
申请日：1990-11-20
申请人： Karoly Magyar , Ferenc Simon , Janos Varga , Attila Nagy , Laszlo Puskas , Pal Fekete , Janos Egri , Katalin Zukovics
发明人： Karoly Magyar , Ferenc Simon , Janos Varga , Attila Nagy , Laszlo Puskas , Pal Fekete , Janos Egri , Katalin Zukovics
IPC分类号： A61K38/00 , A61K38/04 , A61P15/00 , A61P15/14
CPC分类号： A61K38/04
摘要： The invention relates to synergistically active veterinary compositions useful particularly for the treatment of mastitis and metritis. The invention further relates to a process for preparing these compositions. The compositions according to the invention comprise, based on 1 part by weight of 6,9,18-tris(2-aminoethyl) -15-benzyl-21-[.sup.- 2,8-bis(2-aminoethyl)-5-(1-hydroxyethyl) -15-methyl-4,7,10-trioxo-3,6,9-triazaheptadecanamido]-3-(1-hydroxyethyl)-12-isobutyl-1,4,7,10,13,16,19-heptaazacyclotricosane-2, 5,8,11,14,17,20-heptaone or a pharmaceutically acceptable acid addition salt thereof, 1 to 1000 parts by weight of 1-(2-chlorophenyl)-diphenylmethyl-1H-imidazole or 1 to 400 parts by weight of 2-methyl-5,7-dichloro-8-hydroxyquinoline, respectively, optionally in admixture with carriers and/or additives commonly used in the pharmaceutical industry.
摘要翻译：本发明涉及特别用于治疗乳腺炎和子宫炎的协同作用的兽医学组合物。本发明还涉及制备这些组合物的方法。根据本发明的组合物包含基于1重量份的6,9,18-三（2-氨基乙基）-15-苄基-21 - [ - 2,8-双（2-氨基乙基）-5-（ 1-羟乙基）-15-甲基-4,7,10-三氧代-3,6,9-三氮杂十七烷酰胺基] -3-（1-羟基乙基）-12-异丁基-1,4,7,10,13,16 ，19-七氮杂环五烷-2,5,8,11,14,17,20-七酮或其药学上可接受的酸加成盐，1〜1000重量份的1-（2-氯苯基） - 二苯基甲基-1H-咪唑或 1至400份（重量）的2-甲基-5,7-二氯-8-羟基喹啉，分别任选与制药工业中通常使用的载体和/或添加剂混合。

3. 发明授权

US4871722A Synergistic veterinary composition and/or fodder premix and process for preparing same 失效
标题翻译：协同的兽医成分和/或饲料预混物及其制备方法
公开(公告)号：US4871722A
公开(公告)日：1989-10-03
申请号：US158757
申请日：1988-02-22
申请人： Karoly Magyar , Janos Varga , Ferenc Simon , Hedvig Szauder nee Lauko , Pal Fekete , Attila Romvary , Janos Egri , Katalin Zukovics nae Someg
发明人： Karoly Magyar , Janos Varga , Ferenc Simon , Hedvig Szauder nee Lauko , Pal Fekete , Attila Romvary , Janos Egri , Katalin Zukovics nae Someg
IPC分类号： A23K1/16 , A23K1/18 , A61K31/505 , A61K31/635 , A61P31/04 , C07D239/49 , C07D239/52
CPC分类号： A61K31/635 , G05B2219/36242
摘要： The invention relates to a synergistic veterinary composition and/or a fodder premix useful for preventing or curing bacterial, fungal and protozoic infection particularly occurring at poultry species. Furthermore the invention relates to a process for preparing same. The composition or premix contains 1 to 100 parts by mass of 2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine and/or 1 to 100 parts by mass of 2,4-diamino-5-(3,4-dimethoxybenzyl)pyrimidine as well as 1 to 100 parts by mass of 2,6-dimethoxy-4-sulfanilamidopyrimidine or a pharmaceutically acceptable salt thereof and 1 to 100 parts by mass of 8-hydroxyquinoline or a pharmaceutically acceptable acid addition salt thereof optionally in admixture with carrier(s) and/or additive(s) commonly used in the pharmaceutical industry or for the preparation of premixes.
摘要翻译：本发明涉及可用于预防或治愈特别发生在家禽物种上的细菌，真菌和原生动物感染的协同兽药组合物和/或饲料预混物。此外，本发明涉及其制备方法。该组合物或预混物含有1〜100质量份的2,4-二氨基-5-（3,4,5-三甲氧基苄基）嘧啶和/或1〜100质量份的2,4-二氨基-5-（3 ，4-二甲氧基苄基）嘧啶，以及1〜100质量份的2,6-二甲氧基-4-磺胺基脒基嘧啶或其药学上可接受的盐和1〜100质量份的8-羟基喹啉或其药学上可接受的酸加成盐任选地与制药工业中通常使用的载体和/或添加剂混合或用于制备预混物。

4. 发明授权

US4680315A Powder mixture having high propylene glycol content and process for the preparation thereof 失效
标题翻译：具有高丙二醇含量的粉末混合物及其制备方法
公开(公告)号：US4680315A
公开(公告)日：1987-07-14
申请号：US689222
申请日：1985-01-07
申请人： Denes Bezzegh , Karoly Magyar , Jozsef Kelemen , Gabor Zalai , Attila Mandi , Janos Egri
发明人： Denes Bezzegh , Karoly Magyar , Jozsef Kelemen , Gabor Zalai , Attila Mandi , Janos Egri
IPC分类号： A23K1/16 , A23K1/175 , A61K31/047 , A61K47/02 , C07C29/94 , A61K31/045
CPC分类号： C07C29/94 , A23K20/105 , A23K20/24 , A23K20/28 , A61K31/047 , A61K47/02
摘要： The invention refers to a powder mixture having a high propylene glycol content and a process for the preparation thereof. The powder mixture consists of 25 to 75 percent by weight of propylene glycol and 75 to 25 percent by weight of magnesium oxide and/or magnesium peroxide and/or magnesium carbonate as a solid carrier(s). The powder mixture can be treated as a solid powder and it does not deliquesce in the air even when stored for a long time. The mixture can be used as solid propylene glycol in dietetic products for calf, piglet and lamb, in pharmaceutical compositions for the treatment of ketosis and in other pharmaceutical compositions for veterinary use.
摘要翻译：本发明涉及具有高丙二醇含量的粉末混合物及其制备方法。粉末混合物由25至75重量％的丙二醇和75至25重量％的氧化镁和/或氧化镁和/或碳酸镁作为固体载体组成。粉末混合物可以作为固体粉末处理，即使长时间储存也不会在空气中潮解。在用于治疗酮症的药物组合物和用于兽医用途的其它药物组合物中，该混合物可用作小牛，小猪和羔羊的饮食产品中的固体丙二醇。

5. 发明授权

US4871728A Pharmaceutical composition comprising an organic zinc complex and a process for preparing the active substance 失效
标题翻译：包含有机锌络合物的药物组合物和制备活性物质的方法
公开(公告)号：US4871728A
公开(公告)日：1989-10-03
申请号：US232162
申请日：1988-08-12
申请人： Gyula Sebestyen , Istvan Simonyi , Gizelle Miholics , Marta Kovacs , Frigyes Gorgenyi , Marton Fekete , Pal Vago , Istvan Seres , Janos Egri , Maria Szeli
发明人： Gyula Sebestyen , Istvan Simonyi , Gizelle Miholics , Marta Kovacs , Frigyes Gorgenyi , Marton Fekete , Pal Vago , Istvan Seres , Janos Egri , Maria Szeli
IPC分类号： A61K31/555 , A61P31/04 , A61P31/10 , C07D215/30
CPC分类号： C07D215/30
摘要： The invention refers to a novel pharmaceutical composition having especially antimycotic activity and comprising the zinc complex of 5-chloro-7-iodo-8-hydroxyquinoline of formula (I) ##STR1## and one or more pharmaceutically acceptable carriers. The pharmaceutical composition of the invention can be used for the effective treatment of mycotic infections on the skin surface, mucous membranes or nails.The complex of formula (I) is prepared by reacting a solution of an alkali metal salt of 5-chloro-7-iodo-8-hydroxyquinoline with a solution containing an excess of an inorganic or organic zinc salt or a zinc complex having a lower stability constant than that of the complex of formula (I) and separating the product precipitated.
摘要翻译：本发明涉及具有特异性抗真菌活性的新型药物组合物，其包含式（I）的5-氯-7-碘-8-羟基喹啉与一种或多种药学上可接受的载体的锌络合物。本发明的药物组合物可用于有效治疗皮肤表面，粘膜或指甲上的霉菌感染。式（I）的络合物通过使5-氯-7-碘-8-羟基喹啉的碱金属盐溶液与含有过量的无机或有机锌盐的溶液或具有较低的稳定常数比式（I）的络合物和分离产物沉淀。

6. 发明申请

US20090281143A1 Dose Reduction of a Cannabinoid CB1 Receptor Antagonist in the Treatment of Overweight or Obesity 审中-公开
标题翻译：大麻素CB1受体拮抗剂治疗超重或肥胖的剂量减少
公开(公告)号：US20090281143A1
公开(公告)日：2009-11-12
申请号：US12331890
申请日：2008-12-10
申请人： Peter Literati Nagy , Zoltan Szilvassy , Kalman Tory , Attila Kolonics , Sandor Bernath , Laszlo Vigh , Jesse Roth , G. Alexander Fleming , Michael Brownstein , Janos Egri
发明人： Peter Literati Nagy , Zoltan Szilvassy , Kalman Tory , Attila Kolonics , Sandor Bernath , Laszlo Vigh , Jesse Roth , G. Alexander Fleming , Michael Brownstein , Janos Egri
IPC分类号： A61K31/4545 , A61P3/04
CPC分类号： A61K31/454 , A61K31/4545 , A61K45/06 , A61K2300/00
摘要： O-(3-Piperidino-2-hydroxy-1-propyl)-nicotinic amidoxime or a pharmaceutically acceptable acid addition salt thereof is administered to patients suffering from overweight or obesity and treated with a cannabinoid CB1 receptor antagonist such as rimonabant to reduce overweight or obesity and, preferably, reduce one or more unfavourable psychiatric side effects of the cannabinoid CB1 receptor antagonist.
摘要翻译：向患有超重或肥胖症的患者施用O-（3-哌啶子基-2-羟基-1-丙基） - 烟酰胺偕胺肟或其药学上可接受的酸加成盐，并用大麻素CB1受体拮抗剂如利莫那班治疗以减少超重或肥胖症，并且优选地减少大麻素CB1受体拮抗剂的一种或多种不利的精神病学副作用。

7. 发明授权

US4396877A Reversible electric drive with bidirectional back-current brake and fed by a rectifier supplied from alternating current mains, preferably for motor arc furnace regulators 失效
标题翻译：具有双向回流制动器的可逆电驱动器，由交流电源供电的整流器供电，优选用于电动机电弧炉调节器
公开(公告)号：US4396877A
公开(公告)日：1983-08-02
申请号：US246477
申请日：1981-03-23
申请人： Janos Egri , Gyoorgy Kucsera
发明人： Janos Egri , Gyoorgy Kucsera
IPC分类号： H02P7/00 , H02P7/292 , H05B7/144 , H02P5/40
CPC分类号： H05B7/144 , H02P7/05 , H02P7/293 , Y02P10/256 , Y02P10/259
摘要： A reversible electric drive with bidirectional back-current brakes fed by a rectifier supplied from a pair of A.C. power lines for a D.C. motor having two directions of rotation and two poles, comprises a control rectifier bridge for each direction of rotation, each bridge having two branches each containing a diode which is common to both bridges, a shunt resistor for each direction of rotation which is identical with a braking resistor for each other direction of rotation connected in series with the motor for each bridge, each bridge having two other branches each containing a rectifier thyristor with cathodes of each rectifier thyristor connected to a common point. The common point of each bridge is connected to one of the poles of the motor with a control thyristor connected to each common point in series with each respective shunt resistor of each bridge and connected to each other by a connecting point. The common diode is connected to the connecting point, and a braking thyristor is provided between a connecting point of each braking thyristor is provided between a connecting point of each shunt resistor and its respective control thyristor and the common points respectively.
摘要翻译：具有由用于具有两个旋转方向和两极方向的直流电动机的一对AC电力线提供的整流器馈送的具有双向逆流制动器的可逆电驱动器包括用于每个旋转方向的控制整流桥，每个桥具有两个每个桥具有两个桥两个共同的二极管，每个旋转方向的分流电阻器，与用于每个桥接器与电动机串联的每个其他旋转方向的制动电阻器相同，每个桥接器具有两个其他分支包含整流晶闸管，其每个整流晶闸管的阴极连接到公共点。每个桥的公共点连接到电动机的极之一，控制晶闸管连接到每个公共点，每个公共点与每个桥的每个相应的分流电阻串联，并通过连接点彼此连接。公共二极管连接到连接点，并且在每个制动晶闸管的连接点分别设置在每个分流电阻器的连接点及其相应的控制晶闸管和公共点之间的制动晶闸管。

8. 发明申请

US20080108673A1 Prevention and Treatment of Obesity 失效
标题翻译：预防和治疗肥胖
公开(公告)号：US20080108673A1
公开(公告)日：2008-05-08
申请号：US11687945
申请日：2007-03-19
申请人： Peter Literati Nagy , Zoltan Szilvassy , Kalman Tory , Laszlo Vigh , Kalman Takacs , Jozsef Mandl , Balazs Sumegi , Sandor Bernath , Attila Kolonics , Gabor Balogh , Janos Egri
发明人： Peter Literati Nagy , Zoltan Szilvassy , Kalman Tory , Laszlo Vigh , Kalman Takacs , Jozsef Mandl , Balazs Sumegi , Sandor Bernath , Attila Kolonics , Gabor Balogh , Janos Egri
IPC分类号： A61K31/44 , A61P3/04
CPC分类号： A61K31/4545 , Y10S514/909
摘要： O-(3-piperidino-2-hydroxypropyl)-nicotinic amidoxime or a pharmaceutically suitable acid addition salt thereof (BGP-15) can be used for the prevention or reduction of weight gain or the reduction of the rate of body weight.
摘要翻译： O-（3-哌啶子基-2-羟丙基） - 烟酰胺肟或其药学上合适的酸加成盐（BGP-15）可以用于预防或减轻体重增加或减轻体重。

9. 发明授权

US5489615A Pharmaceutical ointment being free from skin irritative action and a process for the preparation thereof 失效
标题翻译：药膏不含皮肤刺激作用及其制备方法
公开(公告)号：US5489615A
公开(公告)日：1996-02-06
申请号：US171471
申请日：1993-12-22
申请人： Margit Nagy nee Kricsfalussy , Maria Hoor , Maria Szeli nee Seger , Janos Egri , Rita Balazs , Marta Kovacs , Gyula Sebestyen , Antal Mosonyi
发明人： Margit Nagy nee Kricsfalussy , Maria Hoor , Maria Szeli nee Seger , Janos Egri , Rita Balazs , Marta Kovacs , Gyula Sebestyen , Antal Mosonyi
IPC分类号： C07D417/12 , A61K9/00 , A61K9/06 , A61K31/54 , A61K31/5415 , A61K47/00 , A61K47/08 , A61K47/14 , A61K47/32 , A61P17/00 , A61P29/00
CPC分类号： A61K9/0014 , A61K31/54 , Y10S514/969
摘要： A pharmaceutical ointment is disclosed containing to 10 percent by mass of micronized piroxicam, 15 to 30 percent by mass of hydrophobic carrier(s), 60 to 75 percent by mass of water, 0.1 to 10 percent by mass of additive(s), and 2 to 5 percent by mass of emulsifiers selected from (i) a poly(ethylene glycol) alkyl or alkenyl ether and (ii) a sorbitane ester of a fatty acid or an oleic acid in a mass ratio of 3:1 to 1:3. The ointment is free from skin irritative action and has local antiphlogistic activity. In addition, a process for preparing he pharmaceutical ointment is provided.
摘要翻译：公开了一种药膏，其含有10质量％的微粉化吡罗昔康，15〜30质量％的疏水性载体，60〜75质量％的水，0.1〜10质量％的添加剂，以及选自（i）聚（乙二醇）烷基或链烯基醚的乳化剂为2〜5质量％，（ii）脂肪酸或油酸的山梨糖醇酯的质量比为3:1〜1:3 。软膏无皮肤刺激作用，具有局部消炎作用。此外，还提供了制备药物软膏的方法。

10. 发明授权

US5240662A Process for the preparation of solid pharmaceutical compositions 失效
标题翻译：制备固体药物组合物的方法
公开(公告)号：US5240662A
公开(公告)日：1993-08-31
申请号：US827397
申请日：1992-01-29
申请人： Sandor Erdos , Denes Bezzegh , Janos Egri , Erzsebet Barczay , Olga Magyar , Katalin Sumeg
发明人： Sandor Erdos , Denes Bezzegh , Janos Egri , Erzsebet Barczay , Olga Magyar , Katalin Sumeg
IPC分类号： A61K9/22 , A61K9/20 , A61K9/28 , A61K31/19 , A61K31/195 , A61K31/198 , A61K47/20 , A61K47/38 , A61P25/14 , C07C229/36 , C07C243/18
CPC分类号： A61K9/2077 , A61K31/195 , A61K9/2004
摘要： The invention relates to a process for the preparation of solid pharmaceutical compositions. More specifically, the invention relates to a process for the preparation of tablets ensuring an increased active ingredient release, where said tablets comprise as active ingredient a mixture of L-3,4-dihydroxyphenylalanine and L-alpha-hydrazino-alpha-methyl-3,4-dihydroxyphenyl propionic acid in a (3-12):1 mass to mass ratio, which comprises admixing any of L-3,4-dihydroxyphenylalanine and L-alpha-hydrazino-alpha-methyl-3,4-dihydroxyphenyl propionic acid, or both of them, with a hydrophilic diluent, preferably lactose and/or microcrystalline cellulose, and optionally with a colouring agent, blending the mixture thus obtained with auxiliary agents conventionally used for the preparation of tablets and optionally with the other active ingredient, furthermore with a solution of stearin in an appropriate solvent, preferably an alkanol comprising 2 to 4 carbon atoms, drying and granulating the mixture thus obtained, optionally admixing further auxiliary agent(s) to the dry granulate, compressing it into tablets comprising 50 to 70% by mass of active ingredient and, if desired, applying a film-coating onto the surface of the tablets thus obtained. The process according to the invention provides tablets of appropriate quality with rapid active ingredient release.

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