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    • 1. 发明授权
    • N-acyl-2,3-benzoidazepine derivatives, pharmaceutical compositions
containing them and process for preparing same
    • N-酰基-2,3-苯并吖庚因衍生物,含有它们的药物组合物及其制备方法
    • US5519019A
    • 1996-05-21
    • US472454
    • 1995-06-07
    • Ferenc AndrasiPal BerzsenyiPeter BotkaSandor FarkasKatalin GoldschmidtTamas HamoriJeno KorosiImre MoravcsikIstvan Tarnawa
    • Ferenc AndrasiPal BerzsenyiPeter BotkaSandor FarkasKatalin GoldschmidtTamas HamoriJeno KorosiImre MoravcsikIstvan Tarnawa
    • C07D491/04A61K31/55C07D243/02
    • C07D491/04
    • The invention relates to novel N-acyl-2,3-benzodiezapine derivatives of the general formula (I), their stereoisomers and acid-addition salts, pharmaceutical compositions containing them and a process for their preparation. In the general formula (I)R stands for a C.sub.1-6 alkanoyl group optionally substituted by a methoxy, cyano, carboxyl, amino, C.sub.1-4 alkylamino, di(C.sub.1-4 alkyl)amino, pyrrolidino, phthalimido or phenyl group, or by one or more halogen(s); or R is a benzoyl, cyclopropanecarbonyl, C.sub.1-5 alkylcarbamoyl or phenylcarbamoyl group; or R is absent when a double bond exists between the N(3) and C(4) atoms;R.sup.1 means hydrogen; or R.sup.1 is absent when a double bond exists between the N(3) and C(4) atoms;R.sup.2 means a C.sub.1-3 alkyl group; orR.sup.1 and R.sup.2 together stand for a methylene group and no double bond is present between the N(3) and C(4) atoms;R.sup.3 means hydrogen or a C.sub.1-4 alkanoyl group;R.sup.4 represents hydrogen; a C.sub.1-6 alkanoyl group optionally substituted by a methoxy, cyano, carboxyl, amino, C.sub.1-4 alkylamino, di(C.sub.1-4 alkyl)amino, pyrrolidino, phthalimido or phenyl group or by one or more halogen(s); as well as a benzoyl, palmitoyl, cyclopropane-carbonyl, C.sub.1-5 alkylcarbamoyl or phenylcarbamoyl group; andthe dotted lines represent valence bonds optionally being present, with the proviso that no double bond exists between the N(3) and C(4) atoms when both R.sup.3 and R.sup.4 stand for hydrogen.The compounds of the general formula (I) possess valuable central nervous system effects, particularly muscle-relaxant, anticonvulsive and neuroprotective action. Thus, they may be useful for the treatment of various diseases of central nervous system origin.
    • 本发明涉及通式(I)的新型N-酰基-2,3-苯并二氮杂萘衍生物,其立体异构体和酸加成盐,含有它们的药物组合物及其制备方法。 在通式(I)中,R代表任选被甲氧基,氰基,羧基,氨基,C 1-4烷基氨基,二(C 1-4烷基)氨基,吡咯烷子基,邻苯二甲酰亚胺基或苯基取代的C 1-6烷酰基,或 通过一个或多个卤素; 或R是苯甲酰基,环丙烷羰基,C 1-5烷基氨基甲酰基或苯基氨基甲酰基; 或者当N(3)和C(4)原子之间存在双键时,R不存在; R1表示氢; 当N(3)和C(4)原子之间存在双键时,R1不存在; R2表示C1-3烷基; 或者R 1和R 2一起代表亚甲基,N(3)和C(4)原子之间不存在双键; R3表示氢或C1-4烷酰基; R4代表氢; 任选被甲氧基,氰基,羧基,氨基,C1-4烷基氨基,二(C1-4烷基)氨基,吡咯烷子基,苯二甲酰亚氨基或苯基或一个或多个卤素取代的C 1-6烷酰基; 以及苯甲酰基,棕榈酰基,环丙烷 - 羰基,C 1-5烷基氨基甲酰基或苯基氨基甲酰基; 并且虚线表示任选存在的价键,条件是当R3和R4均代表氢时,N(3)和C(4)原子之间不存在双键。 通式(I)的化合物具有有价值的中枢神经系统作用,特别是肌肉松弛剂,抗惊厥和神经保护作用。 因此,它们可用于治疗中枢神经系统起源的各种疾病。
    • 2. 发明授权
    • N-acyl-2,3-benzodiazepine derivatives for treating acute and chronic
neurodegenerative disorders
    • 用于治疗急性和慢性神经变性疾病的N-酰基-2,3-苯并二氮杂衍生物
    • US5639751A
    • 1997-06-17
    • US477801
    • 1995-06-07
    • Ferenc AndrasiPal BerzsenyiPeter BotkaSandor FarkasKatalin GoldschmidtTamas HamoriJeno KorosiImre MoravcsikIstvan Tarnawa
    • Ferenc AndrasiPal BerzsenyiPeter BotkaSandor FarkasKatalin GoldschmidtTamas HamoriJeno KorosiImre MoravcsikIstvan Tarnawa
    • C07D491/04A61K31/55A61K31/44
    • C07D491/04
    • The invention relates to novel N-acyl-2,3-benzodiezapine derivatives of the general formula (I), their stereoisomers and acid-addition salts, pharmaceutical compositions containing them and a process for their preparation. In the general formula (I)R stands for a C.sub.1-6 alkanoyl group optionally substituted by a methoxy, cyano, carboxyl, amino, C.sub.1-4 alkylamino, di(C.sub.1-4 alkyl)amino, pyrrolidino, phthalimido or phenyl group, or by one or more halogen(s); or R is a benzoyl, cyclopropanecarbonyl, C.sub.1-5 alkylcarbamoyl or phenylcarbamoyl group; or R is absent when a double bond exists between the N(3) and C(4) atoms;R.sup.1 means hydrogen; or R.sup.1 is absent when a double bond exists between the N(3) and C(4) atoms;R.sup.2 means a C.sub.1-3 alkyl group; orR.sup.1 and R.sup.2 together stand for a methylene group and no double bond is present between the N(3) and C(4) atoms;R.sup.3 means hydrogen or a C.sub.1-4 alkanoyl group;R.sup.4 represents hydrogen; a C.sub.1-6 alkanoyl group optionally substituted by a methoxy, cyano, carboxyl, amino, C.sub.1-4 alkylamino, di(C.sub.1-4 alkyl)amino, pyrrolidino, phthalimido or phenyl group or by one or more halogen(s); as well as a benzoyl, palmitoyl, cyclopropanecarbonyl, C.sub.1-5 alkylcarbamoyl or phenylcarbamoyl group; andthe dotted lines represent valence bonds optionally being present, with the proviso that no double bond exists between the N(3) and C(4) atoms when both R.sup.3 and R.sup.4 stand for hydrogen.The compounds of the general formula (I) possess valuable central nervous system effects, particularly muscle-relaxant, anticonvulsive and neuroprotective action. Thus, they may be useful for the treatment of various diseases of central nervous system origin.
    • 本发明涉及通式(I)的新型N-酰基-2,3-苯并二氮杂萘衍生物,其立体异构体和酸加成盐,含有它们的药物组合物及其制备方法。 在通式(I)中,R代表任选被甲氧基,氰基,羧基,氨基,C 1-4烷基氨基,二(C 1-4烷基)氨基,吡咯烷子基,邻苯二甲酰亚胺基或苯基取代的C 1-6烷酰基,或 通过一个或多个卤素; 或R是苯甲酰基,环丙烷羰基,C 1-5烷基氨基甲酰基或苯基氨基甲酰基; 或者当N(3)和C(4)原子之间存在双键时,R不存在; R1表示氢; 当N(3)和C(4)原子之间存在双键时,R1不存在; R2表示C1-3烷基; 或者R 1和R 2一起代表亚甲基,N(3)和C(4)原子之间不存在双键; R3表示氢或C1-4烷酰基; R4代表氢; 任选被甲氧基,氰基,羧基,氨基,C1-4烷基氨基,二(C1-4烷基)氨基,吡咯烷子基,苯二甲酰亚氨基或苯基或一个或多个卤素取代的C 1-6烷酰基; 以及苯甲酰基,棕榈酰基,环丙烷羰基,C 1-5烷基氨基甲酰基或苯基氨基甲酰基; 并且虚线表示任选存在的价键,条件是当R3和R4均代表氢时,N(3)和C(4)原子之间不存在双键。 通式(I)的化合物具有有价值的中枢神经系统作用,特别是肌肉松弛剂,抗惊厥和神经保护作用。 因此,它们可用于治疗中枢神经系统起源的各种疾病。
    • 3. 发明授权
    • N-acyl-2,3-benzodiazepine derivatives pharmaceutical compositions
containing them and process for preparing same
    • N-酰基-2,3-苯并二氮杂衍生物含有它们的药物组合物及其制备方法
    • US5536832A
    • 1996-07-16
    • US423153
    • 1995-04-17
    • Ferenc AndrasiPal BerzsenyiPeter BotkaSandor FarkasKatalin GoldschmidtTamas HamoriJeno KorosiImre MoravcsikIstvan Tarnawa
    • Ferenc AndrasiPal BerzsenyiPeter BotkaSandor FarkasKatalin GoldschmidtTamas HamoriJeno KorosiImre MoravcsikIstvan Tarnawa
    • A61K31/55A61K20060101A61K31/00A61K31/335A61K31/395A61K31/551A61P9/08A61P9/10A61P21/02A61P25/00A61P25/08A61P25/28C07D20060101C07D243/00C07D243/02C07D247/00C07D317/00C07D317/08C07D317/44C07D491/00C07D491/04C07D491/056C07D493/04
    • C07D491/04
    • The invention relates to novel N-acyl-2,3-benzodiezapine derivatives of the general formula (I), their stereoisomers and acid-addition salts, pharmaceutical compositions containing them and a process for their preparation. In the general formula (I)R stands for a C.sub.1-6 alkanoyl group optionally substituted by a methoxy, cyano, carboxyl, amino, C.sub.1-4 alkylamino, di(C.sub.1-4 alkyl)amino, pyrrolidino, phthalimido or phenyl group, or by one or more halogen(s); or R is a benzoyl, cyclopropanecarbonyl, C.sub.1-5 alkylcarbamoyl or phenylcarbamoyl group; or R is absent when a double bond exists between the N(3) and C(4) atoms;R.sup.1 means hydrogen; or R.sup.1 is absent when a double bond exists between the N(3) and C(4) atoms;R.sup.2 means a C.sub.1-3 alkyl group; orR.sup.1 and R.sup.2 together stand for a methylene group and no double bond is present between the N(3) and C(4) atoms;R.sup.3 means hydrogen or a C.sub.1-4 alkanoyl group;R.sup.4 represents hydrogen; a C.sub.1-6 alkanoyl group optionally substituted by a methoxy, cyano, carboxyl, amino, C.sub.1-4 alkylamino, di(C.sub.1-4 alkyl)amino, pyrrolidino, phthalimido or phenyl group or by one or more halogen(s); as well as a benzoyl, palmitoyl, cyclopropane-carbonyl, C.sub.1-5 alkylcarbamoyl or phenylcarbamoyl group; andthe dotted lines represent valence bonds optionally being present, with the proviso that no double bond exists between the N(3) and C(4) atoms when both R.sup.3 and R.sup.4 stand for hydrogen.The compounds of the general formula (I) possess valuable central nervous system effects, particularly muscle-relaxant, anticonvulsive and neuroprotective action. Thus, they may be useful for the treatment of various diseases of central nervous system origin.
    • 本发明涉及通式(I)的新型N-酰基-2,3-苯并二氮杂萘衍生物,其立体异构体和酸加成盐,含有它们的药物组合物及其制备方法。 在通式(I)中,R代表任选被甲氧基,氰基,羧基,氨基,C 1-4烷基氨基,二(C 1-4烷基)氨基,吡咯烷子基,邻苯二甲酰亚胺基或苯基取代的C 1-6烷酰基,或 通过一个或多个卤素; 或R是苯甲酰基,环丙烷羰基,C 1-5烷基氨基甲酰基或苯基氨基甲酰基; 或者当N(3)和C(4)原子之间存在双键时,R不存在; R1means氢; 当N(3)和C(4)原子之间存在双键时,R1不存在; R2表示C1-3烷基; 或者R 1和R 2一起代表亚甲基,N(3)和C(4)原子之间不存在双键; R3表示氢或C1-4烷酰基; R4表示氢; 任选被甲氧基,氰基,羧基,氨基,C 1-4烷基氨基,二(C 1-4烷基)氨基,吡咯烷子基,苯二甲酰亚氨基或苯基或被一个或多个卤素取代的C 1-6烷酰基; 以及苯甲酰基,棕榈酰基,环丙烷 - 羰基,C 1-5烷基氨基甲酰基或苯基氨基甲酰基; 并且虚线表示任选存在的价键,条件是当R3和R4均代表氢时,N(3)和C(4)原子之间不存在双键。 通式(I)的化合物具有有价值的中枢神经系统作用,特别是肌肉松弛剂,抗惊厥和神经保护作用。 因此,它们可用于治疗中枢神经系统起源的各种疾病。
    • 7. 发明授权
    • System and method for automatic module selection
    • 自动模块选择的系统和方法
    • US08762592B2
    • 2014-06-24
    • US11468622
    • 2006-08-30
    • Sandor FarkasJohn S. Loffink
    • Sandor FarkasJohn S. Loffink
    • G06F3/00
    • G06F1/26
    • A selecting device that receives a digital connector ID signal and that generates a device output signal, the connector ID signal being representative of a connector ID for a connector that receives a server module, the device output signal being indicative of whether the server module is selected as a master server. Generating a signal indicative of an information handling system module rank includes generating a connector ID signal when a module is coupled to a chassis connector having a connector ID associated therewith, the connector ID signal being representative of the connector ID, receiving the connector ID signal at a selecting device, and generating a device output signal using the selecting device, the device output signal being indicative of a module rank.
    • 一种选择装置,其接收数字连接器ID信号并产生装置输出信号,所述连接器ID信号表示用于接收服务器模块的连接器的连接器ID,所述装置输出信号指示是否选择了服务器模块 作为主服务器。 产生指示信息处理系统模块等级的信号包括当模块耦合到具有与其相关联的连接器ID的机架连接器时产生连接器ID信号,连接器ID信号代表连接器ID,接收连接器ID信号 选择装置,以及使用所述选择装置产生装置输出信号,所述装置输出信号指示模块等级。
    • 10. 发明授权
    • System and method for current measurement
    • 用于电流测量的系统和方法
    • US07719293B2
    • 2010-05-18
    • US11938323
    • 2007-11-12
    • Sandor Farkas
    • Sandor Farkas
    • G01R27/08
    • G01R19/0092
    • Load current of a circuit is determined across a component of the circuit by calibrating the resistance of the component with a reference current having a distinguishable characteristic. For example, a reference current with swept frequency modulation is applied to the component so that the resistance of the component is determined from voltage drop associated with the reference current across the component. The component resistance is applied to a voltage drop associated with the load current to determine the load current. For example, a filter matched to the reference current frequency modulation isolates the reference current voltage drop so that a ratio of the reference current voltage drop and the load current voltage drop provides a ratio of the reference current and load current.
    • 通过用具有可区分特性的参考电流校准元件的电阻来确定电路的元件的负载电流。 例如,具有扫频调制的参考电流被施加到组件,使得通过与组件上的参考电流相关联的电压降来确定组件的电阻。 元件电阻被施加到与负载电流相关联的电压降以确定负载电流。 例如,与参考电流频率调制相匹配的滤波器隔离参考电流电压降,使得参考电流电压降与负载电流电压降的比率提供参考电流和负载电流的比率。