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    • 7. 发明申请
    • Systems And Methods For Leukoreducing A Red Blood Cell-Containing Fluid And Concentrated Red Blood Cells
    • 用于白血病诱导的含有红细胞的液体和浓缩红细胞的系统和方法
    • US20160289638A1
    • 2016-10-06
    • US14677319
    • 2015-04-02
    • Fenwal, Inc.
    • Daniel R. LynnDaryl R. Calhoun
    • C12N5/078
    • C12N5/0641A61M1/0218A61M1/0272A61M1/265A61M1/3633A61M2202/0429
    • Systems and methods are provided for separating a red blood cell-containing fluid into separated red blood cells and another fluid constituent. A suitable system includes a disposable fluid flow circuit and a durable, reusable separation system, with the circuit being mounted onto or otherwise associated with the separation system. The circuit includes a membrane separator for separating the fluid into its constituent parts, as well as a leukoreduction filter. The leukoreduction filter may be used before or after the red blood cell-containing fluid has been passed into the membrane separator. The red blood cell-containing fluid (if the leukoreduction filter is positioned upstream of the membrane separator) or the separated red blood cells (if the leukoreduction filter is positioned downstream of the membrane separator) may also be passed through a microaggregate filter prior to passing through the leukoreduction filter.
    • 提供了用于将含红细胞的流体分离成分离的红细胞和另一种流体成分的系统和方法。 合适的系统包括一次性流体流动回路和耐用的可重复使用的分离系统,其中电路安装在分离系统上或以其它方式与分离系统相关联。 电路包括用于将流体分离成其组成部分的膜分离器,以及白细胞减压过滤器。 白细胞减退过滤器可以在含有红细胞的流体进入膜分离器之前或之后使用。 含红细胞的流体(如果白细胞减少过滤器位于膜分离器的上游)或分离的红细胞(如果白细胞减少过滤器位于膜分离器的下游)也可以在通过之前通过微聚集过滤器 通过白细胞减少过滤器。