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1. 发明授权

US08392357B1 Trust network to reduce e-mail spam 有权
标题翻译：信任网络来减少垃圾邮件
公开(公告)号：US08392357B1
公开(公告)日：2013-03-05
申请号：US12262441
申请日：2008-10-31
申请人： Fei Zou , Jianxin Guo
发明人： Fei Zou , Jianxin Guo
IPC分类号： G06F7/00 , G06F17/00
CPC分类号： H04L63/1416 , H04L51/12
摘要： A trust network database has any number of nodes, each node representing a user e-mail address. Links between nodes represent whether one user trusts another. Trust (that the recipient is trusted) is established when a sender sends an e-mail message to a recipient. The recipient is effectively placed on the white list for the sender. A legitimate e-mail address creates a strong trust link, otherwise it is weak. A spam count tracks by an amount of spam sent by each node. Outgoing e-mail messages are screened to make a determination that the sender trusts the recipient and that information is added to a local or remote trust network. Incoming e-mail messages are first screened to determine that the sender is legitimate. Then, the sender and recipient e-mail addresses are forwarded to the trust network to make a determination as to whether the recipient trusts the sender. A score (based upon number and type of links into or out of a node, the spam count for the node, etc.) for the sender is returned indicating whether or not the e-mail message is likely to be spam. An anti-spam engine is bypassed, used normally, or used aggressively based upon the score.
摘要翻译：信任网络数据库具有任意数量的节点，每个节点表示用户电子邮件地址。节点之间的链接表示一个用户是否信任另一个用户。当发件人向收件人发送电子邮件消息时，建立信任（收件人信任）。收件人有效地放在发件人的白名单上。一个合法的电子邮件地址创建一个强大的信任链接，否则它是弱的。垃圾邮件数量跟踪每个节点发送的垃圾邮件数量。筛选出外发电子邮件以确定发件人信任收件人，并将该信息添加到本地或远程信任网络。首先对接收的电子邮件进行筛选，以确定发件人是否合法。然后，将发送方和收件人电子邮件地址转发到信任网络，以确定收件人是否信任发件人。返回发送方的分数（基于进入或退出节点的数量和类型，节点的垃圾邮件计数等），指示电子邮件消息是否可能是垃圾邮件。基于分数，反垃圾邮件引擎被绕过，正常使用或积极使用。

2. 发明申请

US20130317540A1 UNIVERSAL BIOABSORBABLE NASAL IMPLANT KIT 审中-公开
标题翻译：通用生物安全的NASAL IMPLANT KIT
公开(公告)号：US20130317540A1
公开(公告)日：2013-11-28
申请号：US13477474
申请日：2012-05-22
申请人： Krasimira Hristov , Gaoyuan Gavin Chen , Mark T. Mooney , James A. Matrunich , Jianxin Guo , Emil Richard Skula
发明人： Krasimira Hristov , Gaoyuan Gavin Chen , Mark T. Mooney , James A. Matrunich , Jianxin Guo , Emil Richard Skula
IPC分类号： A61F5/08
CPC分类号： A61F2/186 , A61F5/08 , A61F2210/0004
摘要： Novel bioabsorbable, universal kits used to form nasal implants are disclosed. The implants are useful in rhinoplasty and nasal reconstruction surgical procedures. The kit devices have a universal configuration and can be converted by the surgeon in the field into one or more individual nasal implant devices having different configurations and applications. The kits may have outlines of nasal implants thereon.
摘要翻译：公开了用于形成鼻腔植入物的新型生物可吸收的通用试剂盒。植入物在鼻整形术和鼻重建手术中是有用的。套件装置具有通用结构，并且可以由现场的外科医生转换成具有不同构造和应用的一个或多个单独的鼻植入装置。试剂盒可能具有其上的鼻植入物的轮廓。

3. 发明授权

US08648177B2 Lyophilization methods, compositions, and kits 有权
标题翻译：冻干方法，组合物和试剂盒
公开(公告)号：US08648177B2
公开(公告)日：2014-02-11
申请号：US13510401
申请日：2010-11-23
申请人： Jianxin Guo , Anthony Klos , Deborah Barnette
发明人： Jianxin Guo , Anthony Klos , Deborah Barnette
IPC分类号： A61K35/16 , C07K16/06 , C07K14/745
CPC分类号： A61K9/19
摘要： Method for lyophilization is provided, in particular methods for lyophilization of formulations comprising AT III. Also provided are compositions prepared by therefrom. Also provided are kits comprising the compositions and/or lyophilized products.
摘要翻译：提供冻干方法，特别是冻干包含AT III的制剂的方法。还提供了由其制备的组合物。还提供了包含组合物和/或冻干产品的试剂盒。

4. 发明授权

US08480737B2 Columellar strut for nasal tip support 有权
标题翻译：用于鼻尖支撑的Columellar支柱
公开(公告)号：US08480737B2
公开(公告)日：2013-07-09
申请号：US12891019
申请日：2010-09-27
申请人： Krasimira Hristov , Gavin Chen , Jianxin Guo , James A. Matrunich
发明人： Krasimira Hristov , Gavin Chen , Jianxin Guo , James A. Matrunich
IPC分类号： A61F2/18
CPC分类号： A61F2/186
摘要： Novel bioabsorbable, columellar strut implants are disclosed. The struts are useful in rhinoplasty and nasal reconstruction surgical procedures. The devices have opposed lateral sides connected to a spine member to form a tissue-receiving channel.
摘要翻译：公开了新颖的生物可吸收的金黄色支柱植入物。支架可用于鼻整形术和鼻腔重建外科手术。这些装置具有相对于连接到脊骨构件的侧面以形成组织接收通道。

5. 发明申请

US20130040890A1 LYOPHILIZATION METHODS, COMPOSITIONS, AND KITS 有权
标题翻译： LYOPHILIZATION方法，组合物和工具
公开(公告)号：US20130040890A1
公开(公告)日：2013-02-14
申请号：US13510401
申请日：2010-11-23
申请人： Jianxin Guo , Anthony Klos , Deborah Barnette
发明人： Jianxin Guo , Anthony Klos , Deborah Barnette
IPC分类号： A61K38/57 , A61P7/02
CPC分类号： A61K9/19
摘要： Method for lyophilization is provided, in particular methods for lyophilization of formulations comprising AT III. Also provided are compositions prepared by therefrom. Also provided are kits comprising the compositions and/or lyophilized products.
摘要翻译：提供冻干方法，特别是冻干包含AT III的制剂的方法。还提供了由其制备的组合物。还提供了包含组合物和/或冻干产品的试剂盒。

6. 发明授权

US09510940B2 Bioabsorbable multilayer nasal valve spreader graft 有权
标题翻译：生物可吸收多层鼻阀扩张器移植
公开(公告)号：US09510940B2
公开(公告)日：2016-12-06
申请号：US13029541
申请日：2011-02-17
申请人： G. Gavin Chen , Krasimira Hristov , Jianxin Guo , James A. Matrunich , Jianguo Jack Zhou
发明人： G. Gavin Chen , Krasimira Hristov , Jianxin Guo , James A. Matrunich , Jianguo Jack Zhou
IPC分类号： A61F2/18 , A61M29/00 , B29C45/73 , A61B17/80
CPC分类号： A61F2/186 , A61B17/8061 , A61F2210/0004 , A61F2240/001 , B29C45/73 , B29K2067/04 , B29K2995/006 , B29L2031/7532
摘要： Novel bioabsorbable, nasal spreader graft implant devices are disclosed. The devices are useful in rhinoplasty and nasal reconstruction surgical procedures, as well as other surgical procedures. The devices have biodegradable core plates and biodegradable spreader plates or tissue ingrowth plates. The plates may have tissue ingrowth properties.
摘要翻译：公开了新型生物可吸收的鼻扩张器移植物植入装置。这些装置可用于鼻整形术和鼻重建手术以及其他外科手术。这些装置具有可生物降解的芯板和可生物降解的扩张板或组织向内生长板。板可以具有组织向内生长特性。

7. 发明申请

US20130131192A1 COMPOSITION, METHOD, AND KIT FOR ALPHA-1 PROTEINASE INHIBITOR 审中-公开
标题翻译： ALPHA-1蛋白酶抑制剂的组成，方法和试剂盒
公开(公告)号：US20130131192A1
公开(公告)日：2013-05-23
申请号：US13504783
申请日：2010-11-02
申请人： Jianxin Guo , Anthony Klos , Bret Coldren , Deborah Barnette , Mark Manning
发明人： Jianxin Guo , Anthony Klos , Bret Coldren , Deborah Barnette , Mark Manning
IPC分类号： A61K47/18 , A61K47/20 , A61K47/22
CPC分类号： A61K47/183 , A61K9/0019 , A61K9/19 , A61K31/185 , A61K31/195 , A61K38/16 , A61K38/17 , A61K45/06 , A61K47/02 , A61K47/20 , A61K47/22 , A61K47/26 , A61K2300/00
摘要： The present invention provides compositions comprising API and at least one amino acid, in particular a liquid API formulation comprising amino acids, and methods and kits related thereto. These amino acids when incorporated into the API composition afford stability to the API formulation.
摘要翻译：本发明提供包含API和至少一种氨基酸的组合物，特别是包含氨基酸的液体API制剂，以及与其相关的方法和试剂盒。当掺入API组合物中时，这些氨基酸提供对API制剂的稳定性。

8. 发明申请

US20120215307A1 BIOABSORBABLE MULTILAYER NASAL VALVE SPREADER GRAFT 有权
标题翻译：可生物多层纳米阀门溢流板
公开(公告)号：US20120215307A1
公开(公告)日：2012-08-23
申请号：US13029541
申请日：2011-02-17
申请人： G. Gavin Chen , Krasimira Hristov , Jianxin Guo , James A. Matrunich , Jianguo Jack Zhou
发明人： G. Gavin Chen , Krasimira Hristov , Jianxin Guo , James A. Matrunich , Jianguo Jack Zhou
IPC分类号： A61F2/18
CPC分类号： A61F2/186 , A61B17/8061 , A61F2210/0004 , A61F2240/001 , B29C45/73 , B29K2067/04 , B29K2995/006 , B29L2031/7532
摘要： Novel bioabsorbable, nasal spreader graft implant devices are disclosed. The devices are useful in rhinoplasty and nasal reconstruction surgical procedures, as well as other surgical procedures. The devices have biodegradable core plates and biodegradable spreader plates or tissue ingrowth plates. The plates may have tissue ingrowth properties.
摘要翻译：公开了新型生物可吸收的鼻扩张器移植物植入装置。这些装置可用于鼻整形术和鼻重建手术以及其他外科手术。这些装置具有可生物降解的芯板和可生物降解的扩张板或组织向内生长板。板可以具有组织向内生长特性。

9. 发明申请

US20120078367A1 COLUMELLAR STRUT FOR NASAL TIP SUPPORT 有权
标题翻译：用于NASAL提示支持的COLUMELLAR STRUT
公开(公告)号：US20120078367A1
公开(公告)日：2012-03-29
申请号：US12891019
申请日：2010-09-27
申请人： Krasimira Hristov , Gavin Chen , Jianxin Guo , James A. Matrunich
发明人： Krasimira Hristov , Gavin Chen , Jianxin Guo , James A. Matrunich
IPC分类号： A61F2/18
CPC分类号： A61F2/186
摘要： Novel bioabsorbable, columellar strut implants are disclosed. The struts are useful in rhinoplasty and nasal reconstruction surgical procedures. The devices have opposed lateral sides connected to a spine member to form a tissue-receiving channel.
摘要翻译：公开了新颖的生物可吸收的金黄色支柱植入物。支架可用于鼻整形术和鼻腔重建外科手术。这些装置具有相对于连接到脊骨构件的侧面以形成组织接收通道。

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