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    • 5. 发明申请
    • Collagen density and structural change measurement and mapping in tissue
    • 胶原密度和组织结构变化测量和绘图
    • US20070173720A1
    • 2007-07-26
    • US11656315
    • 2007-01-19
    • Everette BurdetteScott Huntley
    • Everette BurdetteScott Huntley
    • A61B8/00
    • G01S7/52071A61B8/08G06T7/0012G06T2207/10132G06T2207/30024
    • A method and system for two and three dimensional mapping of tissue density and/or structural changes from image data and/or spatial reflected or transmitted signal maps, and correlating the maps to changes in collagen density. The method and system includes the steps of: receiving an image or spatial maps of acoustic-derived RF signal data from tissue comprised of multiple pixels, segregating the image into groups of pixels, each group of pixels having characteristics within a defined class, establishing a baseline set of classes corresponding to initial conditions of the imaged/mapped tissue, measuring a differential in the set of classes for a group of pixels, the differential corresponding to a change in pixel values for the group of pixels, correlating said measured differential to a density change for the tissue corresponding to the group of pixels, and overlaying an indication of collagen density over the tissue image or mapped signal responses correlated with thermal dose indicating a change in collagen density for the tissue.
    • 一种用于从图像数据和/或空间反射或发射信号图中组织密度和/或结构变化的二维和三维映射的方法和系统,并且将该图与胶原密度变化相关联。 所述方法和系统包括以下步骤:从由多个像素组成的组织接收声学导出的RF信号数据的图像或空间图,将图像分离成像素组,每组像素具有在限定类别内的特征,建立 对应于成像/映射组织的初始条件的类的基准集合,测量一组像素的类的集合中的差分,所述差异对应于所述像素组的像素值的变化,将所述测量的差分与 对应于该组像素的组织的密度变化,并且覆盖组织图像上的胶原密度的指示或与表示组织的胶原密度变化的热剂量相关的映射信号响应。