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1. 发明授权

US4137117A Method of making a solvent-bonded joint 失效
标题翻译：制造溶剂接合接头的方法
公开(公告)号：US4137117A
公开(公告)日：1979-01-30
申请号：US776430
申请日：1977-03-10
申请人： Eugene C. Jones
发明人： Eugene C. Jones
IPC分类号： A61J1/00 , A61J1/05 , A61M39/12 , B29C65/48 , B29C65/54 , F16L47/02 , B29C27/02
CPC分类号： A61J1/05 , A61J1/00 , A61M39/12 , B29C65/4895 , B29C66/1122 , B29C66/534 , F16L47/02 , B29C65/482 , B29C65/54 , B29C65/548 , B29C66/5344 , B29C66/71 , B29L2031/7148 , Y10S16/40 , Y10S285/915
摘要： A solvent-bonded joint between plastic members, and a method of making the same, particularly useful where such members are intended to convey flowable materials such as sterile medical solutions. The joint includes a pair of members joined at a zone of interference, a tapered crevice between the members, a solvent bond in the tapered crevice, and a series of spacers extending along the entrance to the crevice. The spacers or nubs are provided by one or both of the members and maintain the walls at the entrance of the crevice in uniformally-spaced and stressed condition to facilitate introduction of solvent and to insure proper bonding of the parts even where such parts are formed of flexible plastic material. The zone of interference serves as a barrier against any flowable material entering the tapered crevice in the opposite direction prior to formation of the solvent bond and further serves as a barrier against the escape of solvent through the crevice or the contamination by solvent of any material beyond or below the crevice.
摘要翻译：在塑料构件之间的溶剂接合接头及其制造方法，特别是在这种构件用于输送可流动材料如无菌医疗溶液的情况下特别有用。接头包括在干涉区域处连接的一对构件，构件之间的锥形缝隙，锥形缝隙中的溶剂粘合以及沿着缝隙的入口延伸的一系列间隔件。间隔件或凸块由一个或两个构件提供，并且在缝隙的入口处以均匀间隔和应力状态保持壁，以便于引入溶剂并且确保零件的正确粘合，即使这些部件由柔性塑料材质。在形成溶剂粘合之前，干扰区域可以作为抵抗任何可流动材料在相反方向上进入锥形缝隙的屏障，并且还可以作为防止溶剂逸出的障碍物，或通过任何材料的溶剂污染超过或在缝隙之下。

2. 发明授权

US3992587A Remote data line monitor 失效
标题翻译：远程数据线监控
公开(公告)号：US3992587A
公开(公告)日：1976-11-16
申请号：US498615
申请日：1974-08-19
申请人： Dennis E. Puckett , Dale A. Heatherington , Eugene C. Jones
发明人： Dennis E. Puckett , Dale A. Heatherington , Eugene C. Jones
IPC分类号： H04M11/06 , H04Q9/00
CPC分类号： H04M11/06 , Y10S379/906
摘要： A device that permits local or remote access to data circuits for the purpose of monitoring, testing and performing diagnostics. It may be used to issue commands to perform various functions whereby the device couples a given circuit to a telephone line in response to coded signals identifying the device and the circuit to be interrogated.
摘要翻译：允许本地或远程访问数据电路以进行监视，测试和执行诊断的设备。它可以用于发出命令以执行各种功能，由此设备响应于识别设备和要被询问的电路的编码信号将给定的电路耦合到电话线路。

3. 发明授权

US4106654A Container with side sealing closure and method of forming the seal thereof 失效
标题翻译：具有侧密封的容器和形成其密封件的方法
公开(公告)号：US4106654A
公开(公告)日：1978-08-15
申请号：US776436
申请日：1977-03-10
申请人： Eugene C. Jones
发明人： Eugene C. Jones
IPC分类号： B65D41/04 , B65D51/18
CPC分类号： B65D41/0428 , B65D51/18 , B65D2251/0015 , B65D2251/0078
摘要： An improved seal between a flexible plastic container and its closure cap, wherein the cap is provided with an internal annular shoulder engaging the tapered side surface of an annular lip provided by the neck of the container. The shoulder bears inwardly against the lip with a force sufficient to flex that lip inwardly and maintain the same in a condition of stress. Ideally, the cap is formed of a plastic of limited heat shrinkability at autoclaving temperatures; therefore, heat sterilization of the sealed container and its contents results in slight contraction of the cap and further increases the integrity of the seal. Where the container is formed of plastic material capable of softening slightly at autoclaving temperatures, the shoulder tends to penetrate the lip to a limited extent during such autoclaving to create an undercut in the lip. Later, when the contents of the container are to be used, removal of the closure produces an audible click as the shoulder is drawn from the undercut, thereby indicating that the seal has been broken.
摘要翻译：柔性塑料容器与其封闭帽之间的改进的密封，其中所述盖设置有接合由所述容器的颈部提供的环形唇缘的锥形侧表面的内部环形肩部。肩部以足以使唇部向内弯曲并在压力状态下保持相同的力向内靠在唇部。理想情况下，盖子由高压灭菌温度下的热收缩能力有限的塑料制成; 因此，密封容器及其内容物的加热灭菌导致盖的轻微收缩，并进一步提高密封的完整性。在容器由能够在高压灭菌温度下稍微软化的塑料材料形成的情况下，在这样的高压灭菌过程中，肩部倾向于在有限的程度上渗入唇部，从而在唇部中形成底切。之后，当使用容器的内容物时，由于从底切中抽出肩膀，所以封闭物的移除会产生可听到的咔嗒声，从而表明密封件已被破坏。

4. 发明授权

US06916305B2 Method of loading drug delivery pack 失效
标题翻译：药物递送包装方法
公开(公告)号：US06916305B2
公开(公告)日：2005-07-12
申请号：US10339715
申请日：2003-01-08
申请人： Eugene C. Jones , Michael A. Taylor
发明人： Eugene C. Jones , Michael A. Taylor
IPC分类号： A61J3/00 , A61J1/00 , A61M5/14 , A61M37/00
CPC分类号： A61M5/1409 , A61M2202/064
摘要： Several improvements are disclosed for a drug delivery pack with dry reagent in a housing, each of which can be employed independently or in conjunction with others of the improvements. A novel spring is provided with two spring columns extending in parallel between a spring top and a spring bottom. The spring is particularly designed for fitting within the housing and compacting a dry reagent bed. A plunger mechanism to ratchet housing portions between two positions. In one position, a compression component adjacent the reagent bed is relatively uncompressed, such that it does not “set” over time. When the user is about to use the drug delivery device, the plunger is slid to compress the compression component so that it exerts pressure on the reagent bed. A similar sliding mechanism can also divert a stream of diluent through the housing from a priming path, where diluent bypasses the reagent bed, to a functional path passing through and eroding the reagent bed. Additionally, a method is provided for lyophilizing a liquid form of reagent within the housing from which it is to be delivered, thereby avoiding separate lyophilization and separate loading of dry form of the reagent.
摘要翻译：在壳体中公开了具有干试剂的药物递送包的各种改进，每个可以独立地或与其他改进一起使用。一个新的弹簧设有两个在弹簧顶部和弹簧底部之间平行延伸的弹簧柱。弹簧特别设计用于安装在外壳内并压实干试剂床。一种用于在两个位置之间棘轮收纳部分的柱塞机构。在一个位置，邻近试剂床的压缩部件相对未压缩，使得其随着时间不“设定”。当使用者即将使用药物输送装置时，柱塞被滑动以压缩压缩部件，从而对试剂床施加压力。类似的滑动机构还可以将稀释剂流通过壳体从灌注路径转移到通过并侵蚀试剂床的功能路径上。此外，提供了一种用于将液体形式的试剂冻结在壳体内以从其被输送的方法，从而避免单独的冻干和干燥形式的试剂的分离加载。

5. 发明授权

US4256333A Solvent-bonded joint 失效
标题翻译：溶剂接合
公开(公告)号：US4256333A
公开(公告)日：1981-03-17
申请号：US924442
申请日：1978-07-13
申请人： Eugene C. Jones
发明人： Eugene C. Jones
IPC分类号： A61J1/00 , A61J1/05 , A61J1/10 , A61M39/12 , B29C65/48 , B29C65/54 , F16L47/02 , F16L13/10
CPC分类号： A61J1/05 , A61J1/10 , A61M39/12 , B29C65/4895 , B29C66/1122 , B29C66/534 , F16L47/02 , B29C65/54 , B29C65/548 , B29C66/5344 , B29L2031/7148 , Y10S285/915
摘要： A solvent-bonded joint between plastic members, particularly useful where such members are intended to convey flowable materials such as sterile medical solutions. The joint includes a pair of members joined at a zone of interference, a tapered crevice between the members, a solvent bond in the tapered crevice, and a series of spacers extending along the entrance to the crevice.
摘要翻译：在塑料构件之间的溶剂接合接头，特别是在这种构件用于输送可流动材料如无菌医疗溶液的情况下尤其有用。接头包括在干涉区域处连接的一对构件，构件之间的锥形缝隙，锥形缝隙中的溶剂粘合以及沿着缝隙的入口延伸的一系列间隔件。

6. 发明授权

US06527738B1 Drug delivery pack 失效
标题翻译：药物包装
公开(公告)号：US06527738B1
公开(公告)日：2003-03-04
申请号：US09559692
申请日：2000-04-27
申请人： Eugene C. Jones , Michael A. Taylor
发明人： Eugene C. Jones , Michael A. Taylor
IPC分类号： A61M3700
CPC分类号： A61M5/1409 , A61M2202/064
摘要： Several improvements are disclosed for a drug delivery pack with dry reagent in a housing, each of which can be employed independently or in conjunction with others of the improvements. A novel spring is provided with two spring columns extending in parallel between a spring top and a spring bottom. The spring is particularly designed for fitting within the housing and compacting a dry reagent bed. A plunger mechanism to ratchet housing portions between two positions. In one position, a compression component adjacent the reagent bed is relatively uncompressed, such that it does not “set” over time. When the user is about to use the drug delivery device, the plunger is slid to compress the compression component so that it exerts pressure on the reagent bed. A similar sliding mechanism can also divert a stream of diluent through the housing from a priming path, where diluent bypasses the reagent bed, to a functional path passing through and eroding the reagent bed. Additionally, a method is provided for lyophilizing a liquid form of reagent within the housing from which it is to be delivered, thereby avoiding separate lyophilization and separate loading of dry form of the reagent.
摘要翻译：在壳体中公开了具有干试剂的药物递送包的各种改进，每个可以独立地或与其他改进一起使用。一个新的弹簧设有两个在弹簧顶部和弹簧底部之间平行延伸的弹簧柱。弹簧特别设计用于安装在外壳内并压实干试剂床。一种用于在两个位置之间棘轮收纳部分的柱塞机构。在一个位置，邻近试剂床的压缩部件相对未压缩，使得其随着时间不“设定”。当使用者即将使用药物输送装置时，柱塞被滑动以压缩压缩部件，从而对试剂床施加压力。类似的滑动机构还可以将稀释剂流通过壳体从灌注路径转移到通过并侵蚀试剂床的功能路径上。此外，提供了一种用于将液体形式的试剂冻结在壳体内以从其被输送的方法，从而避免单独的冻干和干燥形式的试剂的分离加载。

7. 发明授权

US3945525A Closure system for medical liquid container having low-torque breakaway ring 失效
标题翻译：医用液体容器闭合系统具有低扭矩分离环
公开(公告)号：US3945525A
公开(公告)日：1976-03-23
申请号：US477310
申请日：1974-06-06
申请人： Eugene C. Jones
发明人： Eugene C. Jones
IPC分类号： B65D41/32
CPC分类号： B65D41/32
摘要： A closure system for a medical liquid container having a dispensing outlet surrounded by a flange over which is fitted a plastic cap. The cap is externally threaded and has an outwardly-projecting brim at its lower end overlying the flange. The brim is sealed to the flange along an annular zone having an inner boundary defining an annular line of weakness, and an internally-threaded breakaway ring is threadedly disposed on the cap. The breakaway ring includes a plurality of circumferentially-spaced depending projections for stressing the brim along portions of the annular line of weakness and for initiating and propagating the rupture of the brim as the breakaway ring is screwed downwardly upon the cap.
摘要翻译：一种用于医疗液体容器的封闭系统，具有由凸缘包围的分配出口，在该凸缘上装配有塑料盖。盖子是外螺纹的，并且在其下端具有向外突出的边缘覆盖凸缘。边缘沿着具有限定环形弱化线的内边界的环形区域密封到凸缘，并且内螺纹的分离环螺纹地设置在盖上。分离环包括多个周向间隔开的悬垂突起，用于沿着环形弱化线的部分应力边缘，并且当分离环向下拧到盖上时启动和传播边缘的破裂。

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