专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20070191329A1 Ethylene glycol esters as photoactive agents 审中-公开
标题翻译：乙二醇酯作为光敏剂
公开(公告)号：US20070191329A1
公开(公告)日：2007-08-16
申请号：US11524718
申请日：2006-09-20
申请人： Ethan Sternberg , David Dolphin , Julia Levy , Anna Richter , David Hunt , Ashok Jain , Elizabeth Waterfield , Ronald Boch , Andrew Tovey
发明人： Ethan Sternberg , David Dolphin , Julia Levy , Anna Richter , David Hunt , Ashok Jain , Elizabeth Waterfield , Ronald Boch , Andrew Tovey
IPC分类号： A61K31/555 , C07D487/22 , A61K31/409
CPC分类号： C07D487/22 , A61K41/0071 , G06Q50/22 , Y10S514/825 , Y10S514/885
摘要： New compounds useful in photodynamic therapy are of the formula and their 1,4-diene isomers and the metallated and/or labeled and/or conjugated forms thereof wherein each R1 is independently alkyl(1-6C); each n is independently an integer of 0-6; and R2 is vinyl or a derivative form thereof.
摘要翻译：可用于光动力学治疗的新化合物具有下式及其1,4-二烯异构体及其金属化和/或标记和/或共轭形式，其中每个R 1独立地为烷基（1-6C） ; 每个n独立地为0-6的整数; R 2是乙烯基或其衍生形式。

2. 发明申请

US20050032769A1 Ethylene glycol esters as photoactive agents 有权
标题翻译：乙二醇酯作为光敏剂
公开(公告)号：US20050032769A1
公开(公告)日：2005-02-10
申请号：US10825270
申请日：2004-04-14
申请人： Ethan Sternberg , David Dolphin , Julia Levy , Anna Richter , David Hunt , Ashok Jain , Elizabeth Waterfield , Ronald Boch , Andrew Tovey
发明人： Ethan Sternberg , David Dolphin , Julia Levy , Anna Richter , David Hunt , Ashok Jain , Elizabeth Waterfield , Ronald Boch , Andrew Tovey
IPC分类号： A61K41/00 , C07D487/22 , A61K31/409 , A61K31/555
CPC分类号： C07D487/22 , A61K41/0071 , G06F19/00 , G06Q50/22 , Y10S514/825 , Y10S514/885
摘要： New compounds useful in photodynamic therapy are of the formula and their 1,4-diene isomers and the metallated and/or labeled and/or conjugated forms thereof wherein each R1 is independently alkyl (1-6C); each n is independently an integer of 0-6; and R2 is vinyl or a derivative form thereof.
摘要翻译：可用于光动力学治疗的新化合物具有下式及其1,4-二烯异构体及其金属化和/或标记和/或共轭形式，其中每个R 1独立地为烷基（1-6C）; 每个n独立地为0-6的整数; R 2是乙烯基或其衍生形式。

3. 发明申请

US20080056996A1 PHOTODYNAMIC THERAPY FOR THE TREATMENT OF HAIR LOSS 审中-公开
标题翻译：用于治疗头发损失的光化疗法
公开(公告)号：US20080056996A1
公开(公告)日：2008-03-06
申请号：US11833862
申请日：2007-08-03
申请人： Guillermo Simkim , Anna Richter , David Hunt , John North , Peter Lutwyche , Ronald Boch , Jean-Marie Houle
发明人： Guillermo Simkim , Anna Richter , David Hunt , John North , Peter Lutwyche , Ronald Boch , Jean-Marie Houle
IPC分类号： A61K49/00 , A61K31/555 , A61P17/14
CPC分类号： A61K8/4913 , A61K9/0014 , A61K9/0019 , A61K31/409 , A61K41/0061 , A61K41/0071 , A61K41/0076 , A61K45/06 , A61K47/10 , A61K2800/434 , A61K2800/81 , A61N5/0617 , A61N5/062 , A61Q7/00 , A61K2300/00
摘要： Photodynamic therapy (PDT) is used to stimulate and/or restore hair growth in areas of hair loss. Methods and compositions relating to PDT treatment for alopecia are disclosed. In light of PDT use to remove unwanted hair by inactivating or destroying hair follicles or destroying the tissue feeding the hair follicles, such methods and compositions relate to a surprising and unexpected discovery. PDT permits a means to treat conditions relating to hair loss such as androgenic alopecia, alopecia areata and drug-induced alopecia.
摘要翻译：光动力疗法（PDT）用于刺激和/或恢复脱发区域的头发生长。公开了与脱发的PDT治疗相关的方法和组合物。鉴于PDT，通过灭活或破坏毛囊或破坏喂养毛囊的组织来去除不需要的毛发，这种方法和组合物涉及惊人的和意想不到的发现。 PDT允许治疗与脱发有关的病症的手段，例如雄激素性脱发，斑秃和药物诱发的脱发。

4. 发明申请

US20050187207A1 Immuno-adjuvant PDT treatment of metastatic tumors 有权
标题翻译：免疫辅助PDT治疗转移性肿瘤
公开(公告)号：US20050187207A1
公开(公告)日：2005-08-25
申请号：US10985582
申请日：2004-11-09
申请人： Patrick Curry , Anna Richter , Julia Levy , David Hunt
发明人： Patrick Curry , Anna Richter , Julia Levy , David Hunt
IPC分类号： A61K41/00 , A61K31/409 , A61K31/555
CPC分类号： A61K41/0057 , A61K41/0071
摘要： Immuno-adjuvant photodynamic therapy to treat and prevent metastatic cancer is effected using photosensitizers in combination with immuno-adjuvants to destroy metastatic tumor cells.
摘要翻译：使用光敏剂与免疫佐剂联合以破坏转移性肿瘤细胞来实现治疗和预防转移性癌症的免疫佐剂光动力学治疗。

5. 发明授权

US5789433A Green porphyrins as immunomodulators 失效
公开(公告)号：US5789433A
公开(公告)日：1998-08-04
申请号：US374158
申请日：1995-01-17
申请人： Agnes How-Ching Chan , David William Carey Hunt , Julia Levy , Modestus Onuora Kay Obochi , Anna Richter , Guillermo O. Simkin
发明人： Agnes How-Ching Chan , David William Carey Hunt , Julia Levy , Modestus Onuora Kay Obochi , Anna Richter , Guillermo O. Simkin
IPC分类号： A61K31/40 , A61K31/409 , A61K41/00 , A61P37/00 , A61P37/02 , C08F132/08
CPC分类号： A61K41/0071 , A61K31/40 , C08F132/08
摘要： Green porphyrins act as antigen-specific immunomodulators in the active phase of an immune response to a particular antigen, as well as to interfere with intercellular communication. These effects occur in the absence of radiation absorbed by the green porphyrin.

6. 发明授权

US5945439A Method for destroying or inhibiting growth of unwanted cells or tissues 失效
标题翻译：破坏或抑制不想要的细胞或组织生长的方法
公开(公告)号：US5945439A
公开(公告)日：1999-08-31
申请号：US887087
申请日：1997-07-02
申请人： Anna Richter , Julia G. Levy , David Dolphin
发明人： Anna Richter , Julia G. Levy , David Dolphin
IPC分类号： A61K31/40 , A61K31/409 , A61K41/00 , A61N5/10 , A61P35/00 , A61P43/00
CPC分类号： A61K31/409 , A61K31/40 , A61K41/0038
摘要： This invention is a process for the use of a combination of ionizing radiation in conjunction with certain benzoporphyrin derivative compounds (BPD), preferably the compound benzoporphyrin derivative-monoacid ring-A (BPD-MA), to mediate the destruction of diseased or unwanted cells or tissues. Specifically, the invention is a method in which the sensitizer compounds are administered either systemically or locally to the diseased or unwanted tissue and irradiated with ionizing radiation (such as might be produced by a .sup.60 Co or x-ray source). The treatment with benzoporphyrin derivative compounds appears to sensitize the target cells or tissues in that those cells do not readily recover from irradiation exposure. In addition, the process may be used to lower the effective amount of radiation applied to a particular tissue target.
摘要翻译：本发明是一种使用电离辐射与某些苯并卟啉衍生物化合物（BPD），优选化合物苯并卟啉衍生物 - 一元酸环-A（BPD-MA）结合的介导方法，以介导患病或不需要的细胞的破坏或组织。具体地说，本发明是一种方法，其中将敏化剂化合物全身或局部施用于患病或不想要的组织，并用电离辐射照射（例如可能由60Co或x射线源产生）。用苯并卟啉衍生物化合物的处理似乎使靶细胞或组织敏感，因为这些细胞不容易从照射暴露中恢复。此外，该方法可以用于降低施加到特定组织靶的辐射的有效量。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式