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1. 发明授权

US08553832B2 Device for obtaining perfusion images 有权
标题翻译：用于获得灌注图像的装置
公开(公告)号：US08553832B2
公开(公告)日：2013-10-08
申请号：US11804903
申请日：2007-05-21
申请人： Estelle Camus , Thomas Redel , Martin Ostermeier , Oliver Meissner
发明人： Estelle Camus , Thomas Redel , Martin Ostermeier , Oliver Meissner
IPC分类号： A61B6/00
CPC分类号： A61B6/504 , A61B6/481 , A61B6/503 , A61B6/507 , G06F19/00 , G06F19/321
摘要： A system and method for obtaining perfusion images is disclosed. The system and method includes hardware and software for determining physiological characteristics of a patient and determining imaging parameter values for an imaging modality based on the patient's physiological characteristics. The system also includes a controller operative to receive the imaging parameter values for controlling an X-ray device. The X-ray device is coupled with the controller and acquires projection images of the patient, and outputs the projection images to a perfusion evaluation computer for evaluating the perfusion of an region of interest represented in the projection images. The perfusion rate of the region of interest is then output to an output device, such as a display or printer.
摘要翻译：公开了一种用于获得灌注图像的系统和方法。该系统和方法包括用于确定患者的生理特征的硬件和软件，并且基于患者的生理特征确定成像模态的成像参数值。该系统还包括可操作以接收用于控制X射线装置的成像参数值的控制器。 X射线装置与控制器耦合并获取患者的投影图像，并将投影图像输出到灌注评估计算机，以评估在投影图像中表示的感兴趣区域的灌注。然后将感兴趣区域的灌注速率输出到诸如显示器或打印机的输出装置。

2. 发明授权

US08275448B2 Method for reconstructing a 3D presentation 有权
标题翻译：重建3D演示的方法
公开(公告)号：US08275448B2
公开(公告)日：2012-09-25
申请号：US11715533
申请日：2007-03-08
申请人： Estelle Camus , Thomas Redel
发明人： Estelle Camus , Thomas Redel
IPC分类号： A61B5/05
CPC分类号： A61B6/504 , A61B5/0066 , A61B5/0084 , A61B6/12 , A61B6/4441 , A61B6/466 , A61B6/541 , A61B8/12
摘要： The invention relates to a method for reconstructing a 3D presentation of a hollow organ based on two-dimensional catheter images, comprising: detecting at least two fluoroscopy images at two different angles of the hollow organ; determining a start position of the catheter from the fluoroscopy images in a three-dimensional model of the hollow organ or a catheter guide; determining a probable withdrawal path of the catheter based on the three-dimensional model; withdrawing the catheter while recording the catheter images and assigning a withdrawal length to each catheter image; determining the deviation of the position of the catheter from a central path running through the middle of the hollow organ and the orientation of the catheter for each catheter image based on the withdrawal path and the withdrawal length; and reconstructing the 3D presentation from the two-dimensional catheter images as well as the deviation of the position of the catheter.
摘要翻译：本发明涉及一种基于二维导管图像重建中空器官的3D呈现的方法，包括：在中空器官的两个不同角度检测至少两个荧光透视图像; 在所述中空器官或导管引导件的三维模型中从所述荧光透视图像确定所述导管的开始位置; 基于三维模型确定导管的可能的撤回路径; 在记录导管图像并将抽出长度分配给每个导管图像的同时取出导管; 基于取出路径和取出长度，确定导管的位置与穿过中空器官的中间的中心路径和每个导管图像的导管的取向的偏差; 并从二维导管图像重建3D呈现以及导管位置的偏差。

3. 发明授权

US07945082B2 Analysis method for data of an examination object, featuring correlation of a volume data record with a number of projection images 有权
标题翻译：检查对象的数据分析方法，具有体积数据记录与多个投影图像的相关性
公开(公告)号：US07945082B2
公开(公告)日：2011-05-17
申请号：US11973246
申请日：2007-10-05
申请人： Thomas Redel , Estelle Camus
发明人： Thomas Redel , Estelle Camus
IPC分类号： G06K9/00 , A61B5/05
CPC分类号： A61B6/504 , A61B6/481 , A61B6/507 , G06T7/0012 , G06T7/11 , G06T7/38 , G06T2207/10072 , G06T2207/10116 , G06T2207/30104
摘要： Data of an examination object comprises a volume-data record and a plurality of two-dimensional projection images. The volume-data record includes voxels where each voxel is assigned to a location in three-dimensional space. Each projection image includes pixels where each pixel is assigned to a location in a two-dimensional-projection plane and has a value. Each pixel is assigned a projection volume, this being specified in that it is mapped by the radioscopy onto the pixel to which it is assigned. A sub-volume of the volume-data record is selected. The projection images are registered in relation to the volume-data record. A functional parameter of the examination object is specified for the pixels of the projection images, depending on their values. For each pixel, when specifying the functional parameter, consideration is given to the locations and/or the number of those voxels which are positioned both within the sub-volume and within the projection volume.
摘要翻译：检查对象的数据包括体数据记录和多个二维投影图像。体数据记录包括体素，其中每个体素被分配到三维空间中的位置。每个投影图像包括其中每个像素被分配给二维投影平面中的位置并具有值的像素。每个像素被分配一个投影体积，这被指定为通过放射镜被映射到其被分配到的像素上。选择卷数据记录的子卷。相对于卷数据记录登记投影图像。根据投影图像的像素值，为检查对象的像素指定功能参数。对于每个像素，当指定功能参数时，考虑定位在子体积内和投影体积内的那些体素的位置和/或数量。

4. 发明授权

US07865003B2 Image evaluation method for two-dimensional projection images and objects corresponding thereto 有权
标题翻译：对应于其的二维投影图像和对象的图像评估方法
公开(公告)号：US07865003B2
公开(公告)日：2011-01-04
申请号：US11809073
申请日：2007-05-31
申请人： Estelle Camus , Thomas Redel
发明人： Estelle Camus , Thomas Redel
IPC分类号： G06K9/00 , A61B5/02
CPC分类号： G06T7/0012 , A61B6/507 , G06T2207/10116 , G06T2207/30104
摘要： 2-D projection images show the temporal profile of the distribution of a contrast medium in an examination object, which contains a vascular system and its surroundings. Each projection image comprises pixels with pixel values. The pixel values of pixels corresponding to one another in the projection images are defined by at least essentially locationally identical areas of the examination object. A computer assigns a uniform 2-D evaluation core that is uniform for all corresponding pixels at least in a sub-area of pixels corresponding to one another in the projection images that is uniform for the projection images. The computer defines at least one characteristic value for each pixel within each projection image based on the evaluation core assigned to the pixel and assigns it to the relevant pixel. Based on the temporal profile of the characteristic values, the computer defines parameters of at least one function of time, so that any deviation between the function parameterized with the parameters and the temporal profile of the characteristic values is minimized. Based on the parameters the computer defines a type and/or an extent and assigns them to a pixel of a 2-D evaluation image corresponding to the pixels of the projection images. The type indicates whether the respective pixel of the evaluation image corresponds to a vessel of the vascular system, a perfused part or a non-perfused part of the surroundings of a vessel of the vascular system. The extent is characteristic of perfusion. The computer outputs at least the sub-area of the evaluation image to a user via a display device.
摘要翻译： 2-D投影图像显示了包含血管系统及其周围环境的检查对象中造影剂分布的时间特征。每个投影图像包括具有像素值的像素。在投影图像中彼此对应的像素的像素值由检查对象的至少基本上位置相同的区域限定。计算机为投影图像中均匀的投影图像中至少在彼此对应的像素的子区域中为所有相应像素分配统一的2-D评估内核。计算机基于分配给像素的评估核心为每个投影图像中的每个像素定义至少一个特征值，并将其分配给相关像素。基于特征值的时间特征，计算机定义时间的至少一个函数的参数，使得参数化参数的函数与特征值的时间分布之间的任何偏差最小化。基于参数，计算机定义类型和/或范围，并将它们分配给与投影图像的像素对应的2-D评估图像的像素。该类型指示评估图像的各个像素是否对应于血管系统的血管系统的血管，血管系统的血管周围的灌注部分或非灌注部分。其程度是灌注的特征。计算机至少将评估图像的子区域经由显示装置输出给用户。

5. 发明申请

US20100114289A1 Method and associated device for positioning a stent deployed to support a vessel 有权
标题翻译：用于定位展开用于支撑血管的支架的方法和相关装置
公开(公告)号：US20100114289A1
公开(公告)日：2010-05-06
申请号：US12075442
申请日：2008-03-11
申请人： Estelle Camus , Oliver Meissner , Andreas Meyer , Anton Nekovar , Martin Ostermeier , Thomas Redel
发明人： Estelle Camus , Oliver Meissner , Andreas Meyer , Anton Nekovar , Martin Ostermeier , Thomas Redel
IPC分类号： A61F2/82
CPC分类号： A61F2/95 , A61B5/0452 , A61B6/541 , A61F2/958
摘要： A method for positioning a stent able to be deployed to support a vessel in a blood vessel, especially in the cardiology, with the stent after its provisional placement in a not yet deployed state in an area intended for the support of the vessel, being at least partly automatically deployed as a function of at least one triggering signal for final positioning in the blood vessel.
摘要翻译：一种用于定位支架的方法，所述支架能够展开以支撑血管，特别是在心脏病学中的血管，其中支架在临时放置在尚未部署状态之后，位于用于支撑血管的区域中，处于至少部分地自动部署为至少一个用于血管中最终定位的触发信号的功能。

6. 发明申请

US20070173717A1 Medical apparatus with a multi-modality interface 审中-公开
标题翻译：具有多模态界面的医疗器械
公开(公告)号：US20070173717A1
公开(公告)日：2007-07-26
申请号：US11655958
申请日：2007-01-19
申请人： Estelle Camus , Oliver Meissner , Martin Ostermeier , Thomas Redel
发明人： Estelle Camus , Oliver Meissner , Martin Ostermeier , Thomas Redel
IPC分类号： A61B5/05
CPC分类号： A61B8/12 , A61B5/0084 , A61B8/4416 , A61B2560/045
摘要： The invention relates to a medical examination and/or treatment apparatus comprising an x-ray image recording device, a radiation source, a radiation receiver, a control and processing device and an image generating device, wherein at least one invasive sensor device with an imaging system can be connected to the medical examination and/or treatment apparatus via a multi-modality interface which is implemented as a universal interface via which different invasive sensor devices can be connected.
摘要翻译：本发明涉及包括x射线图像记录装置，辐射源，辐射接收器，控制和处理装置以及图像产生装置的医疗检查和/或治疗装置，其中至少一个具有成像的侵入性传感器装置系统可以经由多模态界面连接到医疗检查和/或治疗装置，该多模式界面被实现为能够连接不同侵入式传感器装置的通用接口。

7. 发明申请

US20070123771A1 Three-dimensional co-registration between intravascular and angiographic data 有权
标题翻译：血管内和血管造影数据之间的三维共同对照
公开(公告)号：US20070123771A1
公开(公告)日：2007-05-31
申请号：US11266886
申请日：2005-11-04
申请人： Thomas Redel , Estelle Camus , Oliver Meissner
发明人： Thomas Redel , Estelle Camus , Oliver Meissner
IPC分类号： A61B5/05
CPC分类号： A61B6/481 , A61B5/0066 , A61B5/7285 , A61B6/466 , A61B6/503 , A61B6/504 , A61B6/5247 , A61B6/541 , A61B8/0891 , A61B8/12 , A61B8/4416
摘要： A method and appertaining system permit a co-registration between points in a three-dimensional model of a vessel and vascular images obtained by an imaging catheter within the vessel at the respective points. The three-dimensional model is created by utilizing information from at least two external two-dimensional images produced by, e.g., one or more x-ray devices. The three-dimensional model is displayed on an analysis workstation, and a user may view the vascular images at particular points by selecting the appertaining points on the three-dimensional model.
摘要翻译：一种方法和附属系统允许在血管的三维模型中的点之间的共同配准和在血管内的成像导管在各个点处获得的血管图像。通过利用由例如一个或多个x射线装置产生的至少两个外部二维图像的信息来创建三维模型。三维模型显示在分析工作站上，用户可以通过选择三维模型上的点来查看特定点的血管图像。

8. 发明申请

US20070055132A1 Catheter device 审中-公开
标题翻译：导管装置
公开(公告)号：US20070055132A1
公开(公告)日：2007-03-08
申请号：US11516142
申请日：2006-09-06
申请人： Estelle Camus , Thomas Redel
发明人： Estelle Camus , Thomas Redel
IPC分类号： A61B5/05 , A61B6/00
CPC分类号： A61M25/1011 , A61B5/0066 , A61M25/007 , A61M2025/0036 , A61M2025/0037 , A61M2025/004 , A61M2025/1052
摘要： Catheter device with an imaging device, in particular for optical coherence tomography, for insertion into a bifurcation region of a vessel of the human or animal body, comprising a main catheter with a balloon arranged thereupon and inflatable via a supply line, for the purpose of occluding the vessel proximal to the bifurcation, with a total of two further occlusion balloons for positioning in one of the two vascular branches in each case distal to the bifurcation being arranged on the main catheter and/or at least one auxiliary catheter, at a distance from the first balloon, such that they can be inflated for the distal occlusion of the respective vascular branch.
摘要翻译：具有成像装置的导管装置，特别是用于光学相干断层摄影，用于插入人体或动物体的血管的分叉区域，包括具有布置在其上的气囊并可经由供应管线充气的主导管，用于闭合分叉处的血管，总共两个另外的闭塞气球用于定位在两个血管分支中的一个中，在远离分叉的每个情况下，布置在主导管和/或至少一个辅助导管上，距离从第一气球，使得它们可以被充气以用于相应血管分支的远端闭塞。

9. 发明授权

US08663300B2 Method and associated device for positioning a stent deployed to support a vessel 有权
标题翻译：用于定位展开用于支撑血管的支架的方法和相关装置
公开(公告)号：US08663300B2
公开(公告)日：2014-03-04
申请号：US12075442
申请日：2008-03-11
申请人： Estelle Camus , Oliver Meissner , Andreas Meyer , Anton Nekovar , Martin Ostermeier , Thomas Redel
发明人： Estelle Camus , Oliver Meissner , Andreas Meyer , Anton Nekovar , Martin Ostermeier , Thomas Redel
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61B5/0452 , A61B6/541 , A61F2/958
摘要： A method for positioning a stent able to be deployed to support a vessel in a blood vessel, especially in the cardiology, with the stent after its provisional placement in a not yet deployed state in an area intended for the support of the vessel, being at least partly automatically deployed as a function of at least one triggering signal for final positioning in the blood vessel.
摘要翻译：一种用于定位支架的方法，所述支架能够展开以支撑血管，特别是在心脏病学中的血管，其中支架在临时放置在尚未部署状态之后，位于用于支撑血管的区域中，处于至少部分地自动部署为至少一个用于血管中最终定位的触发信号的功能。

10. 发明授权

US08103067B2 Analysis method for image data records including automatic specification of analysis regions 有权
标题翻译：图像数据记录分析方法，包括分析区域的自动指定
公开(公告)号：US08103067B2
公开(公告)日：2012-01-24
申请号：US11821054
申请日：2007-06-21
申请人： Jan Boese , Estelle Camus , Marcus Pfister , Thomas Redel
发明人： Jan Boese , Estelle Camus , Marcus Pfister , Thomas Redel
IPC分类号： G06K9/00 , G06K9/34
CPC分类号： G06K9/4642 , G06K2209/05
摘要： There is described an analysis method for at least one image data record of an examination object, wherein each image data record features a multiplicity of image data elements. A position in a multidimensional space is assigned to each image data element. Each image data element features an image data value. The image data values of positionally corresponding image data elements of the image data records are specified by means of at least essentially positionally identical regions of the examination object. A computer automatically divides the image data records into empty regions and signal regions, applying an overall assignment rule which is based on the image data values of the image data elements of a plurality of image data records, such that each image data element of each image data record is assigned to either its empty region or its signal region. For each image data record, the computer automatically determines a closed outline which fully contains the signal region of the relevant image data record and, on the basis of the closed outline of the relevant image data record, determines an analysis region such that a further analysis of the relevant image data record can be restricted to its analysis region.
摘要翻译：描述了用于检查对象的至少一个图像数据记录的分析方法，其中每个图像数据记录具有多个图像数据元素。将多维空间中的位置分配给每个图像数据元素。每个图像数据元素具有图像数据值。图像数据记录的位置对应的图像数据元素的图像数据值通过至少基本位置上相同的检查对象的区域来指定。计算机自动将图像数据记录分为空区域和信号区域，应用基于多个图像数据记录的图像数据元素的图像数据值的总分配规则，使得每个图像的每个图像数据元素数据记录被分配到其空区域或其信号区域。对于每个图像数据记录，计算机自动确定完全包含相关图像数据记录的信号区域的封闭轮廓，并且基于相关图像数据记录的闭合轮廓确定分析区域，使得进一步分析的相关图像数据记录可以限于其分析区域。

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