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1. 发明申请

US20090120443A1 CHIN PIVOT PATIENT INTERFACE DEVICE 有权
标题翻译： CHIN PIVOT患者接口装置
公开(公告)号：US20090120443A1
公开(公告)日：2009-05-14
申请号：US12356948
申请日：2009-01-21
申请人： JEROME MATULA, JR. , Derrick Andrews , Eugene N. Scarberry , Charles Thomas , Erik K. Witt , Peter Chi Fai Ho
发明人： JEROME MATULA, JR. , Derrick Andrews , Eugene N. Scarberry , Charles Thomas , Erik K. Witt , Peter Chi Fai Ho
IPC分类号： A61M16/06
CPC分类号： A61M16/0683 , A61M16/0057 , A61M16/06 , A61M16/0611 , A61M16/0633 , A61M16/0644 , A61M16/0666 , A61M16/0816 , A61M16/0825 , A61M16/0833 , A61M16/0875
摘要： A patient interface device that includes a body portion comprising a pair of arms and a chin support. A first end portion of each arm in the pair of arms is coupled to an opposite end of the chin support. The chin support is adapted to be disposed under the mandible responsive to the patient interface device being donned by a user. At least one headgear attachment element is provided on each arm in the pair of arms. A circuit portion is provided at a second end portion of each arm in the pair of arm. A patient interface portion is coupled to the circuit portion.
摘要翻译：一种患者接口装置，其包括包括一对臂和下巴支撑的主体部分。一对臂中的每个臂的第一端部连接到下巴支撑件的相对端。下颌支撑件适于根据用户穿戴的患者接口装置来设置在下颚下方。在一对臂中的每个臂上设置至少一个头带附接元件。电路部分设置在该对臂中每个臂的第二端部处。患者接口部分耦合到电路部分。

2. 发明申请

US20080302364A1 System and Method for Treating Ventilatory Instability 有权
标题翻译：用于治疗通气不稳定的系统和方法
公开(公告)号：US20080302364A1
公开(公告)日：2008-12-11
申请号：US12133864
申请日：2008-06-05
申请人： Smita Garde , Stephen D. Pittman , Leonardo A. Baloa , Stefanida Blake , Charles Thomas , Manuel Laura , Erik K. Witt
发明人： Smita Garde , Stephen D. Pittman , Leonardo A. Baloa , Stefanida Blake , Charles Thomas , Manuel Laura , Erik K. Witt
IPC分类号： A61M16/00
CPC分类号： A61M16/0045 , A61M16/0075 , A61M16/026 , A61M16/101 , A61M16/201 , A61M16/205 , A61M16/22 , A61M2016/0021 , A61M2016/0036 , A61M2016/1025 , A61M2016/103 , A61M2202/0208 , A61M2202/0225 , A61M2202/03 , A61M2205/3358 , A61M2230/10 , A61M2230/205 , A61M2230/30 , A61M2230/432 , A61M2230/50 , A61M2230/005 , A61M2202/0007
摘要： A therapy system adapted to treat a patient's ventilatory instability using a ventilatory therapy, a gas modulation therapy, or both. The algorithm implemented by the therapy system monitors the ventilatory instability, such as Cheyne Stokes Respiration (CSR), mixed apneas, CPAP emergent apneas, and complex sleep disordered breathing (CSDB) and treats the ventilatory instability. The algorithm also determine a reference point with respect to the ventilatory instability. The therapy delivery system initiate the treatment based on the reference point.
摘要翻译：一种治疗系统，其适于使用通气治疗，气体调节疗法或两者来治疗患者的通气不稳定性。治疗系统实施的算法监测Cheyne Stokes呼吸（CSR），混合呼吸暂停，CPAP紧急呼吸暂停和复杂睡眠呼吸障碍（CSDB）等通气不稳定，并治疗通气不稳定。该算法还确定了相对于通气不稳定性的参考点。治疗递送系统基于参考点开始治疗。

3. 发明授权

US07798146B2 Oral appliance 有权
标题翻译：口腔器具
公开(公告)号：US07798146B2
公开(公告)日：2010-09-21
申请号：US11260554
申请日：2005-10-27
申请人： Erik K. Witt , Charles Thomas
发明人： Erik K. Witt , Charles Thomas
IPC分类号： A61M11/00
CPC分类号： A61M16/0009 , A61F5/56 , A61M16/0493 , A61M2016/0027
摘要： An oral appliance is provided for installation within the oral cavity of a user. The oral appliance is configured to be connected to a negative pressure supply to create a negative pressure environment within the oral cavity of a user. The device includes apertures adjacent the user's teeth.
摘要翻译：提供了用于安装在用户口腔内的口腔器具。口腔器具被配置为连接到负压源以在使用者口腔内产生负压环境。该装置包括邻近使用者牙齿的孔。

4. 发明申请

US20080149105A1 Chin pivot patient interface device 有权
标题翻译：中枢枢轴患者接口装置
公开(公告)号：US20080149105A1
公开(公告)日：2008-06-26
申请号：US11811126
申请日：2007-06-08
申请人： Jerome Matula , Derrick Andrews , Eugene N. Scarberry , Charles Thomas , Erik K. Witt , Peter Chi Fai Ho
发明人： Jerome Matula , Derrick Andrews , Eugene N. Scarberry , Charles Thomas , Erik K. Witt , Peter Chi Fai Ho
IPC分类号： A62B18/08 , A62B18/02
CPC分类号： A61M16/0683 , A61M16/0057 , A61M16/06 , A61M16/0611 , A61M16/0633 , A61M16/0644 , A61M16/0666 , A61M16/0816 , A61M16/0825 , A61M16/0833 , A61M16/0875
摘要： A patient interface device that includes a body portion comprising a pair of arms and a chin support. A first end portion of each arm in the pair of arms is coupled to an opposite end of the chin support. The chin support is adapted to be disposed under the mandible responsive to the patient interface device being donned by a user. At least one headgear attachment element is provided on each arm in the pair of arms. A circuit portion is provided at a second end portion of each arm in the pair of arm. A patient interface portion is coupled to the circuit portion.
摘要翻译：一种患者接口装置，其包括包括一对臂和下巴支撑的主体部分。一对臂中的每个臂的第一端部连接到下巴支撑件的相对端。下颌支撑适于根据用户穿戴的患者接口装置而设置在下颚下方。在一对臂中的每个臂上设置至少一个头带附接元件。电路部分设置在该对臂中每个臂的第二端部处。患者接口部分耦合到电路部分。

5. 发明授权

US08794235B2 System and method for treating ventilatory instability 有权
标题翻译：治疗通气不稳定的系统和方法
公开(公告)号：US08794235B2
公开(公告)日：2014-08-05
申请号：US12133864
申请日：2008-06-05
申请人： Smita Garde , Stephen D. Pittman , Leonardo A. Baloa , Stefanida Blake , Charles Thomas , Manuel Laura , Erik K. Witt
发明人： Smita Garde , Stephen D. Pittman , Leonardo A. Baloa , Stefanida Blake , Charles Thomas , Manuel Laura , Erik K. Witt
IPC分类号： A61M16/00 , A62B7/00 , F16K31/02
CPC分类号： A61M16/0045 , A61M16/0075 , A61M16/026 , A61M16/101 , A61M16/201 , A61M16/205 , A61M16/22 , A61M2016/0021 , A61M2016/0036 , A61M2016/1025 , A61M2016/103 , A61M2202/0208 , A61M2202/0225 , A61M2202/03 , A61M2205/3358 , A61M2230/10 , A61M2230/205 , A61M2230/30 , A61M2230/432 , A61M2230/50 , A61M2230/005 , A61M2202/0007
摘要： A therapy system adapted to treat a patient's ventilatory instability using a ventilatory therapy, a gas modulation therapy, or both. The algorithm implemented by the therapy system monitors the ventilatory instability, such as Cheyne Stokes Respiration (CSR), mixed apneas, CPAP emergent apneas, and complex sleep disordered breathing (CSDB) and treats the ventilatory instability. The algorithm also determine a reference point with respect to the ventilatory instability. The therapy delivery system initiate the treatment based on the reference point.
摘要翻译：一种治疗系统，其适于使用通气治疗，气体调节疗法或两者来治疗患者的通气不稳定性。治疗系统实施的算法监测Cheyne Stokes呼吸（CSR），混合呼吸暂停，CPAP紧急呼吸暂停和复杂睡眠呼吸障碍（CSDB）等通气不稳定，并治疗通气不稳定。该算法还确定了相对于通气不稳定性的参考点。治疗递送系统基于参考点开始治疗。

6. 发明授权

US07500480B2 Chin pivot patient interface device 有权
标题翻译：中枢枢轴患者接口装置
公开(公告)号：US07500480B2
公开(公告)日：2009-03-10
申请号：US11811126
申请日：2007-06-08
申请人： Jerome Matula, Jr. , Derrick Andrews , Eugene N. Scarberry , Charles Thomas , Erik K. Witt , Peter Chi Fai Ho
发明人： Jerome Matula, Jr. , Derrick Andrews , Eugene N. Scarberry , Charles Thomas , Erik K. Witt , Peter Chi Fai Ho
IPC分类号： A62B18/08
CPC分类号： A61M16/0683 , A61M16/0057 , A61M16/06 , A61M16/0611 , A61M16/0633 , A61M16/0644 , A61M16/0666 , A61M16/0816 , A61M16/0825 , A61M16/0833 , A61M16/0875
摘要： A patient interface device that includes a body portion comprising a pair of arms and a chin support. A first end portion of each arm in the pair of arms is coupled to an opposite end of the chin support. The chin support is adapted to be disposed under the mandible responsive to the patient interface device being donned by a user. At least one headgear attachment element is provided on each arm in the pair of arms. A circuit portion is provided at a second end portion of each arm in the pair of arm. A patient interface portion is coupled to the circuit portion.
摘要翻译：一种患者接口装置，其包括包括一对臂和下巴支撑的主体部分。一对臂中的每个臂的第一端部连接到下巴支撑件的相对端。下颌支撑件适于根据用户穿戴的患者接口装置来设置在下颚下方。在一对臂中的每个臂上设置至少一个头带附接元件。电路部分设置在该对臂中每个臂的第二端部处。患者接口部分耦合到电路部分。

7. 发明授权

US08024044B2 Method and apparatus for hypoglossal nerve stimulation 有权
标题翻译：舌下神经刺激的方法和装置
公开(公告)号：US08024044B2
公开(公告)日：2011-09-20
申请号：US12644076
申请日：2009-12-22
申请人： Todd Kirby , Erik K. Witt
发明人： Todd Kirby , Erik K. Witt
IPC分类号： A61N1/18
CPC分类号： A61N1/3601 , A61N1/0526 , A61N1/0548
摘要： A method of treating sleep disordered breathing in a patient includes the steps of monitoring the patient for a pre-inspiratory drive signal indicative of the breathing cycle by sensing electroneurogram activity of a hypoglossal nerve of the patient; and electrically stimulating the hypoglossal nerve of the patient following each detection of the pre-inspiratory drive signal. An implantable apparatus for stimulating a hypoglossal nerve of a patient for the treatment of sleep disordered breathing includes an electrode positioned at least partially around the hypoglossal nerve with a monitoring contact and a stimulation contact and a controller operatively coupled to the monitoring contact and the stimulation contact. The monitoring contact monitors the electroneurogram activity of the hypoglossal nerve for a pre-inspiratory drive signal indicative of the onset of inspiration and sends a signal to the controller which in turn causes the stimulating electrode to electrically stimulate the hypoglossal nerve.
摘要翻译：一种治疗患者睡眠呼吸障碍的方法包括以下步骤：通过感测患者的舌下神经的电图活动来监测患者的吸气前驱动信号，以指示呼吸周期; 并且在每次检测到吸气前驱动信号之后电刺激患者的舌下神经。用于刺激患者的舌下神经以用于治疗睡眠无序呼吸的可植入装置包括至少部分地围绕舌下神经定位的电极，其具有监测接触和刺激接触以及可操作地耦合到监测接触和刺激接触的控制器。监测接触器监测舌下神经的电子图像活动，用于指示吸气开始的吸气前驱动信号，并向控制器发送信号，控制器又引起刺激电极电刺激舌下神经。

8. 发明授权

US07810497B2 Ventilatory control system 有权
标题翻译：通风控制系统
公开(公告)号：US07810497B2
公开(公告)日：2010-10-12
申请号：US11715726
申请日：2007-03-08
申请人： Stephen D. Pittman , Erik K. Witt , Stefanida K. Blake
发明人： Stephen D. Pittman , Erik K. Witt , Stefanida K. Blake
IPC分类号： A62B7/02
CPC分类号： A61M16/209 , A61M16/0045 , A61M16/0066 , A61M16/0069 , A61M16/0072 , A61M16/0075 , A61M16/026 , A61M16/08 , A61M16/1045 , A61M16/16 , A61M16/204 , A61M2016/0036 , A61M2016/1025 , A61M2016/103 , A61M2202/0208 , A61M2202/0225 , A61M2205/502 , A61M2230/10 , A61M2230/202 , A61M2230/205 , A61M2230/43 , A61M2230/432 , A61M2230/435 , A61M2230/60 , Y10S128/914
摘要： A system is provided for delivering a flow of breathing gas to an airway of a patient. The system includes a pressurizing flow module that generates a pressurized flow of breathing gas and a patient circuit coupled to the pressurizing flow module configured to communicate the flow of breathing gas to an airway of a patient. The system includes a sensor for monitoring a characteristic of a breathing pattern of the patient a controller that communicates with the sensor configured to increase a fraction of inspired carbon dioxide if the characteristic exceeds an upper threshold value and to provide servo-ventilation if the characteristic is less than a lower threshold value. The upper threshold value and the lower threshold value are changed based on the monitored characteristic of the breathing pattern of the patient.
摘要翻译：提供一种用于将呼吸气体流输送到患者的气道的系统。该系统包括加压流量模块，其产生加压的呼吸气体流，以及耦合到加压流量模块的患者回路，所述加压流量模块被配置为将呼吸气体流传送到患者的气道。该系统包括用于监测患者呼吸模式特征的传感器，与控制器通信的控制器，所述控制器被配置为如果特征超过上限阈值则增加启发二氧化碳的分数，并且如果特征是小于较低的阈值。上限阈值和下阈值根据患者呼吸模式的监测特征而改变。

9. 发明授权

US08523758B1 System and method of treatment for insomnia and occasional sleeplessness 有权
标题翻译：治疗失眠和偶尔失眠的系统和方法
公开(公告)号：US08523758B1
公开(公告)日：2013-09-03
申请号：US12113916
申请日：2008-05-01
申请人： Todd Kirby , Erik K. Witt , Smita Garde
发明人： Todd Kirby , Erik K. Witt , Smita Garde
IPC分类号： A61M21/00
CPC分类号： A61M21/02 , A61M16/024 , A61M2021/0016 , A61M2021/0022 , A61M2021/0027 , A61M2021/0044 , A61M2205/3306 , A61M2205/3368 , A61M2205/3375 , A61M2230/06 , A61M2230/10 , A61M2230/14 , A61M2230/42 , A61M2230/50 , A61M2230/63
摘要： A system configured to provide breathing cues to a patient to alleviate insomnia or sleeplessness. In one embodiment, the system comprises a pressure support apparatus, a patient monitor, and a processor. The pressure support apparatus is configured to provide a pressurized flow of gas for delivery to an airway of the patient. The patient monitor configured to generate one or more signals that convey information related to one or more physiological functions of the patient. The processor in operative communication with each of the pressure support apparatus and the patient monitor. The processor is configured (i) to determine whether the patient is asleep or awake based at least in part on the one or more signals generated by the patient monitor, and (ii) to control the pressure support apparatus such that if the patient is determined to be awake, one or more properties of the flow of gas are varied according to a first predetermined algorithm designed to provide breathing cues to the patient that prompt the patient to breathe at a target breathing rate.
摘要翻译：一种被配置为向患者提供呼吸提示以减轻失眠或失眠的系统。在一个实施例中，该系统包括压力支持装置，患者监视器和处理器。压力支持装置构造成提供用于输送到患者的气道的气体的加压气流。所述患者监视器被配置为生成一个或多个信号，所述信号传达与患者的一个或多个生理功能相关的信息。处理器与每个压力支持装置和患者监视器进行操作性通信。所述处理器被配置为：（i）至少部分地基于由所述患者监视器产生的一个或多个信号来确定所述患者是否睡着或唤醒，以及（ii）控制所述压力支持设备，使得如果所述患者被确定为了清醒，气体流动的一个或多个性质根据设计用于向患者提供呼吸提示的第一预定算法而改变，以促使患者以目标呼吸速率呼吸。

10. 发明授权

US09743841B2 Automated sleep phenotyping 有权
公开(公告)号：US09743841B2
公开(公告)日：2017-08-29
申请号：US12210244
申请日：2008-09-15
申请人： Stephen D. Pittman , Stefanida K. Blake , Jacobo D. Reif , David P. White , Erik K. Witt
发明人： Stephen D. Pittman , Stefanida K. Blake , Jacobo D. Reif , David P. White , Erik K. Witt
IPC分类号： A61B5/0205 , A61B5/087 , A61B5/00 , A61B5/0488 , A61B5/0496 , A61B5/08 , A61B5/085 , A61B5/11 , A61B5/145
CPC分类号： A61B5/0205 , A61B5/0488 , A61B5/0496 , A61B5/0816 , A61B5/085 , A61B5/087 , A61B5/11 , A61B5/145 , A61B5/4806 , A61B5/4812 , A61B5/4818 , A61B5/4884 , A61M16/00 , A61M16/0045 , A61M16/022 , A61M16/024 , A61M2016/0027 , A61M2016/0033 , A61M2016/103 , A61M2021/0083 , A61M2205/502 , A61M2205/52 , A61M2230/10 , A61M2230/14 , A61M2230/205 , A61M2230/30 , A61M2230/40 , A61M2230/60 , A61M2230/63 , A61M2230/005
摘要： A system that determines one or more sleep phenotyping parameters of a subject. In one embodiment, the system comprises a sleep sensor, a stimulus generator, and a processor. The sleep sensor generates signals that convey information related to the physiological functions that indicate the sleep stage of the subject. The stimulus generator provides a stimulus to the subject that enables information related to the sleep phenotyping parameters to be determined. The processor receives the signals generated by the sleep sensor and is in operative communication with the stimulus generator. The processor (i) determines, based on the signals received from the sleep sensor, whether a trigger condition related to the current sleep stage of the subject is satisfied, (ii) controls the stimulus generator to provide the stimulus to the subject if the trigger condition is satisfied, and (iii) quantifies the response of the subject to the stimulus.

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