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1. 再颁专利

USRE44719E1 Process for producing a triglyceride 有权
标题翻译：甘油三酯的制备方法
公开(公告)号：USRE44719E1
公开(公告)日：2014-01-21
申请号：US13550352
申请日：2012-07-16
申请人： Erik Johan Anton Schweitzer , Frederick William Cain , Ulrike Schmid
发明人： Erik Johan Anton Schweitzer , Frederick William Cain , Ulrike Schmid
IPC分类号： C12P7/64
CPC分类号： C11C3/08 , A23D9/00
摘要： A process for the production of a composition comprising 1,3-dioleyl-2-palmitoyl glyceride (OPO) comprises subjecting a palm oil stearin, with an iodine value (IV) between about 2 and about 12 to enzymic transesterification, with oleic acid or a non-glyceride ester thereof.
摘要翻译：制备包含1,3-二油基-2-棕榈酰甘油酯（OPO）的组合物的方法包括将具有约2至约12的碘值（IV）的棕榈油硬脂精与油酸或其非甘油酯。

2. 发明授权

US08153407B2 Process for producing a triglyceride 有权
标题翻译：甘油三酯的制备方法
公开(公告)号：US08153407B2
公开(公告)日：2012-04-10
申请号：US11991610
申请日：2006-09-08
申请人： Erik Johannes Anton Schweitzer , Frederick William Cain , Ulrike Schmid
发明人： Erik Johannes Anton Schweitzer , Frederick William Cain , Ulrike Schmid
IPC分类号： C12P7/64
CPC分类号： C11C3/08 , A23D9/00
摘要： A process for the production of a composition comprising 1,3-dioleyl-2-palmitoyl glyceride (OPO) comprises subjecting a palm oil stearin, with an iodine value (IV) between about 2 and about 12 to enzymic transesterification, with oleic acid or a non-glyceride ester thereof.
摘要翻译：制备包含1,3-二油基-2-棕榈酰甘油酯（OPO）的组合物的方法包括将具有约2至约12的碘值（IV）的棕榈油硬脂精与油酸或其非甘油酯。

3. 发明申请

US20100029766A1 Blends Comprising a Substituted Fatty Acid or a Derivative Thereof 审中-公开
标题翻译：包含取代脂肪酸或其衍生物的混合物
公开(公告)号：US20100029766A1
公开(公告)日：2010-02-04
申请号：US12508635
申请日：2009-07-24
申请人： Scott Sinclair Barclay , John Anthony Bosley , Frederick William Cain , Claudia Koenen , Julia Sarah Rogers , Ulrike Schmid
发明人： Scott Sinclair Barclay , John Anthony Bosley , Frederick William Cain , Claudia Koenen , Julia Sarah Rogers , Ulrike Schmid
IPC分类号： A61K31/20 , A23D9/00 , A61P7/00 , A61P9/00 , A61P25/00 , A61P35/04
CPC分类号： A23G3/40 , A21D2/16 , A23D7/0053 , A23D9/007 , A23G3/343 , A23G3/346 , A23G9/327 , A23G9/52 , A23G2200/00 , A23L7/122 , A23L7/126 , A23L33/105 , A23L33/115 , A23P20/11
摘要： The invention concerns blends of a hydroquinone substituted poly unsaturated fatty acid (as present in Kombo nut oil) or a derivative thereof, which blends comprised: (i) 0.1-99.9 wt % of the substituted acid (ii) 0-99.8 wt % of Kombo butter glycerides (iii) 0.1-99.9 wt % of other triglycerides Food products and food supplements comprising such hydroquinone substituted acids are also part of the invention.The substituted acids display many useful health benefits.
摘要翻译：本发明涉及氢醌取代的多不饱和脂肪酸（存在于Kombo坚果油中）或其衍生物的共混物，所述共混物包含：（i）0.1-99.9重量％的取代的酸（ii）0-99.8重量％椰子油甘油酯（iii）0.1-99.9重量％的其它甘油三酸酯包含这种氢醌取代的酸的食品和食品补充剂也是本发明的一部分。取代的酸显示出许多有益的健康益处。

4. 发明授权

US06500479B2 Fat blends with crystal modifiers 失效
标题翻译：脂肪与水晶改性剂混合
公开(公告)号：US06500479B2
公开(公告)日：2002-12-31
申请号：US09780478
申请日：2001-02-12
申请人： Krish Bhaggan , Frederick William Cain , John Hugh Pierce , Julia Sarah Rogers , Ulrike Schmid
发明人： Krish Bhaggan , Frederick William Cain , John Hugh Pierce , Julia Sarah Rogers , Ulrike Schmid
IPC分类号： A23D9007
CPC分类号： A23G1/36 , A23D7/0056 , A23D9/007 , A23G1/305 , A23G9/327 , A23G2200/08
摘要： Blends containing a vegetable fat or a blend of vegetable fats and at least 0.1 wt % of a composition comprising ursolic acid and oleanolic acid in a weight ratio of 1:00 to 99:1 display a number of benefits such as high crystallization rates. This modification of the crystallization rate can be used to achieve a number of beneficial effects in the final fat blend or in the final food product containing the blend.
摘要翻译：含有植物脂肪或植物脂肪的混合物和至少0.1重量％的包含熊果酸和齐墩果酸的组合物的重量比为1：00至99：1的混合物显示出许多益处，例如高结晶速率。结晶速率的这种修改可用于在最终的脂肪混合物中或在含有共混物的最终食品中实现许多有益效果。

5. 发明申请

US20110229563A1 Use of compositions comprising oleanic acid and ursolic acid for the preparation of a medicament for the treatment of hypersensitivity and hyperreactivity 审中-公开
标题翻译：使用包含油酸和熊果酸的组合物用于制备用于治疗超敏反应和高反应性的药物
公开(公告)号：US20110229563A1
公开(公告)日：2011-09-22
申请号：US10583151
申请日：2004-12-17
申请人： Frederick William Cain , Wiro Stam , Ulrike Schmid , Geoff Collins
发明人： Frederick William Cain , Wiro Stam , Ulrike Schmid , Geoff Collins
IPC分类号： A61K9/48 , A61K31/19 , A61P37/08 , A61P11/08 , A61K31/215 , C07C61/29
CPC分类号： A61K31/19 , A23L33/12 , A61K9/06 , A61K31/191 , A61K2300/00
摘要： A material comprising from 30 to 80% by weight of ursolic acid, from 2 to 25% by weight of oleanolic acid and from 1 to 68% by weight of triterpenoic acids other than ursolic acid or oleanolic acid, or derivatives of any of these acids, said percentages being based on total weight of said acids or derivatives and the percentages of said acids or derivatives adding up to 100%, can be used in the prevention or treatment of hypersensitivity and/or hyper-reactivity.
摘要翻译：包含30至80重量％的熊果酸，2至25重量％的齐墩果酸和1至68重量％的除熊果酸或齐墩果酸以外的三萜烯酸的物质，或任何这些酸的衍生物，所述百分比基于所述酸或衍生物的总重量，所述酸或衍生物的百分比加至100％，可用于预防或治疗超敏反应和/或高反应性。

6. 发明授权

US06888016B2 Mixtures for stimulating glucose up-take 失效
标题翻译：用于刺激葡萄糖摄取的混合物
公开(公告)号：US06888016B2
公开(公告)日：2005-05-03
申请号：US10260522
申请日：2002-10-01
申请人： Anna Louise Brown , Frederick William Cain , Ingrid Celestina Mohede , Preyesh Parmar , Julia Sarah Rogers , Ulrike Schmid
发明人： Anna Louise Brown , Frederick William Cain , Ingrid Celestina Mohede , Preyesh Parmar , Julia Sarah Rogers , Ulrike Schmid
IPC分类号： A23L33/12 , A61K31/201 , A61K31/231 , A61K31/352 , A61K31/375 , A61K33/24 , A61K36/48 , A61K38/00 , A61K45/00 , A61P3/00 , A61P3/10 , C07C57/00
CPC分类号： A61K31/201 , A23L33/12
摘要： Our invention concerns a mixture of CLA glycerides, and/or CLA-fatty acids and or CLA-alkyl esters and another component, wherein the other component (=component A) is selected for its capacity to alleviate problems related to insulin resistance in mammals, using CLA rich diets and/or foods and/or food supplements using an appropriate in vitro test so that in at least one step of the in vitro test, as described in the text, an improvement in test results is obtained of at least 4% by the blend of the CLA derivative and component A when compared to the CLA derivative only.The inventon further concerns CLA rich dietic food, food supplements and foods containing the combination of CLA and component A as defined, while also the use of this combination for achieving an alleviation of insulin resistance is part of the invention.
摘要翻译：本发明涉及CLA甘油酯和/或CLA-脂肪酸和/或CLA-烷基酯和另一种组分的混合物，其中选择其它组分（=组分A）以减轻哺乳动物胰岛素抵抗相关问题的能力，使用CLA丰富的饮食和/或食物和/或食物补充剂，使用适当的体外试验，使得在体外试验的至少一个步骤中，如文中所述，获得的试验结果的改善至少为4％当与CLA衍生物相比时，通过CLA衍生物和组分A的共混物。本发明进一步涉及CLA富含脂肪的食物，食品添加剂和含有CLA和组分A的组合的食品，同时也使用这种组合来实现胰岛素抵抗的减轻是本发明的一部分。

7. 发明授权

US08183021B2 Process for producing triglycerides 有权
标题翻译：生产甘油三酯的方法
公开(公告)号：US08183021B2
公开(公告)日：2012-05-22
申请号：US11991611
申请日：2006-09-08
申请人： Frederick William Cain , Ulrike Schmid
发明人： Frederick William Cain , Ulrike Schmid
IPC分类号： C12P7/64 , C11C1/00 , C09K3/00 , C11C3/00
CPC分类号： A23D9/00 , C11C3/08 , C11C3/10
摘要： A process for producing triglycerides comprises: (a) subjecting a first triglyceride comprising at least 40% by moles of oleic acid residues, based on total acyl groups in the triglyceride, to a reaction with stearic acid, at least one ester of stearic acid or a mixture thereof, to obtain a composition comprising 1,3-distearoyl 2-oleoyl glyceride and trioleoyl glyceride; (b) treating the composition to form a first fraction having an increased amount by weight of oleoyl groups compared to said composition and a second fraction having an increased amount by weight of stearoyl groups compared to said composition; (c) hydrolysing the first fraction to form oleic acid; and (d) reacting said oleic acid or an ester thereof with a triglyceride comprising at least 50% by moles of palmitic acid residues, based on total acyl groups, to form a composition comprising 1,3-dioleoyl 2-palmitoyl glyceride.
摘要翻译：制备甘油三酸酯的方法包括：（a）使基于甘油三酸酯中的总酰基含有至少40摩尔％油酸残基的第一甘油三酯与硬脂酸，至少一种硬脂酸酯或得到包含1,3-二硬脂基-2-油酰甘油酯和三油酰甘油酯的组合物; （b）与所述组合物相比，处理所述组合物以形成具有增加的油酰基重量的第一级分，和与所述组合物相比，硬脂酰基重量增加的第二级分; （c）水解第一级分以形成油酸; 和（d）使所述油酸或其酯与基于总酰基包含至少50摩尔％棕榈酸残基的甘油三酯反应，形成包含1,3-二油酰2-棕榈酰甘油酯的组合物。

8. 发明授权

US07582317B2 Food supplements comprising, as a health component, sargahydroquinoic acid or derivative thereof 失效
标题翻译：包含作为健康成分的大夸喹酸或其衍生物的食品补充剂
公开(公告)号：US07582317B2
公开(公告)日：2009-09-01
申请号：US10230352
申请日：2002-08-29
申请人： Scott Sinclair Barclay , John Anthony Bosley , Frederick William Cain , Claudia Koenen , Julia Sarah Rogers , Ulrike Schmid
发明人： Scott Sinclair Barclay , John Anthony Bosley , Frederick William Cain , Claudia Koenen , Julia Sarah Rogers , Ulrike Schmid
IPC分类号： A61K36/00 , A01N65/00 , A01N61/00 , A61K31/00 , C09K15/00
CPC分类号： A23G3/40 , A21D2/16 , A23D7/0053 , A23D9/007 , A23G3/343 , A23G3/346 , A23G9/327 , A23G9/52 , A23G2200/00 , A23L7/122 , A23L7/126 , A23L33/105 , A23L33/115 , A23P20/11
摘要： The invention concerns blends of a hydroquinone substituted poly unsaturated fatty acid (as present in Kombo nut oil) or a derivative thereof, which blends comprised: (i) 0.1-99.9 wt % of the substituted acid (ii) 0-99.8 wt % of Kombo butter glycerides (iii) 0.1-99.9 wt % of other triglycerides Food products and food supplements comprising such hydroquinone substituted acids are also part of the invention. The substituted acids display many useful health benefits.
摘要翻译：本发明涉及氢醌取代的多不饱和脂肪酸（存在于Kombo坚果油中）或其衍生物的共混物，该共混物包含：（i）0.1-99.9重量％的取代的酸（ii）0-99.8重量％椰子油甘油酯（iii）0.1-99.9重量％的其它甘油三酸酯包含这种氢醌取代的酸的食品和食品补充剂也是本发明的一部分。取代的酸显示出许多有益的健康益处。

9. 发明申请

US20090123982A1 Triglyceride Process 有权
标题翻译：甘油三酯过程
公开(公告)号：US20090123982A1
公开(公告)日：2009-05-14
申请号：US11991612
申请日：2006-09-08
申请人： John Bernard Harris , Ulrike Schmid , Frederick William Cain
发明人： John Bernard Harris , Ulrike Schmid , Frederick William Cain
IPC分类号： C11C3/08 , C12P7/64
CPC分类号： C12P7/6454 , A23D9/00 , C11C3/003 , C11C3/08 , C11C3/10
摘要： A process for producing triglycerides which comprises: (a) subjecting a first triglyceride comprising at least 40% by moles of oleic acid residues, based on total acyl groups in the triglyceride, to an alcoholysis reaction with an alcohol having from 1 to 6 carbon atoms to obtain a composition comprising 2-oleoyl monoglyceride and at least one acyl ester of said alcohol; (b) reacting the 2-oleoyl monoglyceride with an acylating agent comprising at least one C12 to C24 saturated fatty acid, at least one ester of said fatty acid or a mixture thereof, to obtain a 1,3-saturated fatty acid acyl 2-oleoyl glyceride; and (c) separating at least a part of the at least one acyl ester after or during step (a) or step (b); (d) reacting the acyl ester with a second glyceride to form 1,3-dioleoyl 2-palmitoyl glyceride.
摘要翻译：一种生产甘油三酸酯的方法，其包括：（a）使含有至少40摩尔油酸残基的第一甘油三酸酯以甘油三酸酯中的总酰基为基础与具有1至6个碳原子的醇进行醇解反应以获得包含2-油酰基单甘油酯和至少一种所述醇的酰基酯的组合物; （b）使2-油酰基单酸甘油酯与包含至少一种C 12至C 24饱和脂肪酸，至少一种所述脂肪酸酯或其混合物的酰化剂反应，得到1,3-饱和脂肪酸酰基2- 油酰甘油酯; 和（c）在步骤（a）或步骤（b）之后或之后分离至少一部分所述至少一种酰基酯; （d）使酰基酯与第二甘油酯反应形成1,3-二油酰基2-棕榈酰甘油酯。

10. 发明授权

US07001621B2 Blends of ursolic acid/oleanolic acid 失效
公开(公告)号：US07001621B2
公开(公告)日：2006-02-21
申请号：US09863439
申请日：2001-05-24
申请人： Christiaan Beindorff , Frederick William Cain , John Hugh Pierce , Ulrike Schmid , Erik Schweitzer , Jeroen Nicolaas M. van Straalen
发明人： Christiaan Beindorff , Frederick William Cain , John Hugh Pierce , Ulrike Schmid , Erik Schweitzer , Jeroen Nicolaas M. van Straalen
IPC分类号： A61K35/78
CPC分类号： A23G1/30 , A23D7/0053 , A23D7/0056 , A23D9/007 , A23G1/36 , A23G1/48 , A23G3/36 , A23G3/40 , A23G3/48 , A23G9/32 , A23G9/327 , A23G9/42 , A23L27/60 , A23L27/72 , A23L33/105
摘要： Blends comprising a glyceride and ursolic acid and oleanolic acid in weight ratios of 1:99 to 99:1 that contain less than 20 wt % of natural apolar components and/or low molecular weight components, normally present in natural extract for ursolic acid and oleanolic acid do not display the negative off taste of the natural extracts anymore.

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