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    • 1. 发明授权
    • Controlled activation pH sensor
    • 控制活化pH传感器
    • US08262878B2
    • 2012-09-11
    • US11881021
    • 2007-07-25
    • Erich H. WolfCharles BankertRoss TsukashimaElmer Custodio
    • Erich H. WolfCharles BankertRoss TsukashimaElmer Custodio
    • G01N27/414
    • G01N27/4035
    • The present invention pertains to a means of combining and configuring specific hydrophilic and dielectric materials in such a way as to allow an antimony/reference electrode pH sensor to be packaged and stored dry yet become fully hydrated to an activated state after exposure to aqueous liquids. The sensor is packaged and stored dry to maintain component stability and minimize component degradation. When the user removes the sensor from the package and the sensor tip is submerged in a hydration (ion conduction) media or solution, the hydrophilic coating along with the impregnated reference wick, absorb the fluid to create an electrolytic gel inside the reference wick, which activates the pH sensor.
    • 本发明涉及一种组合和配置特定的亲水和介电材料的方法,其方法是允许锑/参比电极pH传感器在暴露于含水液体之后被干燥而被充分水合至活化状态。 传感器被包装并储存干燥,以保持部件的稳定性并最大程度降低部件的退化。 当使用者从传感器中取出传感器并将传感器尖端浸没在水合(离子传导)介质或溶液中时,亲水涂层与浸渍的参考油芯一起吸收流体,以在参考油芯内部产生电解凝胶, 激活pH传感器。
    • 2. 发明申请
    • Controlled activation pH sensor
    • 控制活化pH传感器
    • US20090026078A1
    • 2009-01-29
    • US11881021
    • 2007-07-25
    • Erich H. WolfCharles BankertRoss TsukashimaElmer Custodio
    • Erich H. WolfCharles BankertRoss TsukashimaElmer Custodio
    • G01N27/406
    • G01N27/4035
    • The present invention pertains to a means of combining and configuring specific hydrophilic and dielectric materials in such a way as to allow an antimony/reference electrode pH sensor to be packaged and stored dry yet become fully hydrated to an activated state after exposure to aqueous liquids. The sensor is packaged and stored dry to maintain component stability and minimize component degradation. When the user removes the sensor from the package and the sensor tip is submerged in a hydration (ion conduction) media or solution, the hydrophilic coating along with the impregnated reference wick, absorb the fluid to create an electrolytic gel inside the reference wick, which activates the pH sensor.
    • 本发明涉及一种组合和配置特定的亲水和介电材料的方法,其方法是允许锑/参比电极pH传感器在暴露于含水液体之后被干燥而被充分水合至活化状态。 传感器被包装并储存干燥,以保持部件的稳定性并最大程度降低部件的退化。 当使用者从传感器中取出传感器并将传感器尖端浸没在水合(离子传导)介质或溶液中时,亲水涂层与浸渍的参考油芯一起吸收流体,以在参考油芯内部产生电解凝胶, 激活pH传感器。
    • 3. 发明申请
    • Hydration monitoring circuitry for pH sensors
    • pH传感器水合监测电路
    • US20060270936A1
    • 2006-11-30
    • US11137459
    • 2005-05-25
    • Ross TsukashimaErich WolfJeffery SchipperCharles BankertLeo RoucherThomas Wallner
    • Ross TsukashimaErich WolfJeffery SchipperCharles BankertLeo RoucherThomas Wallner
    • A61B5/02
    • A61B5/14542A61B5/145A61B5/14539A61B5/1473A61B5/1495A61B2560/0276A61B2562/02
    • The present invention pertains to an apparatus for evaluating the signal strength from the pH sensor to determine whether the sensor is hydrated sufficiently to accurately measure pH. This is accomplished by utilizing circuitry that periodically sends a low voltage signal to a suitable pH sensor and then receiving the resulting waveforms which are analyzed by a processing receiver. The electrical connection between a suitable pH sensor and hydration monitoring circuitry is generally hard wired. In one embodiment, a processing receiver is coupled with the hydration monitoring circuitry as a single apparatus. In a second embodiment, the processing receiver can be independent and located remote from the hydration monitoring circuitry. In this embodiment, the hydration monitoring circuitry and the processing receiver are electrically connected using either hard wired techniques or wireless technology. In addition, the processing receiver can include data recording capability.
    • 本发明涉及一种用于评估来自pH传感器的信号强度以确定传感器是否足够水合以准确测量pH的装置。 这是通过利用周期性地向合适的pH传感器发送低电压信号然后接收由处理接收器分析的结果波形的电路来实现的。 合适的pH传感器和水合监测电路之间的电气连接通常是硬连线的。 在一个实施例中,处理接收器作为单一设备与水合监控电路耦合。 在第二实施例中,处理接收器可以是独立的并且位于远离水合监测电路的位置。 在该实施例中,水合监测电路和处理接收器使用硬接线技术或无线技术进行电连接。 此外,处理接收器可以包括数据记录能力。
    • 4. 发明申请
    • Respiratory monitoring, diagnostic and therapeutic system
    • 呼吸监测,诊断和治疗系统
    • US20070068810A1
    • 2007-03-29
    • US11545182
    • 2006-10-10
    • Ross TsukashimaJeffery SchipperLeo RoucherErich WolfCharles Bankert
    • Ross TsukashimaJeffery SchipperLeo RoucherErich WolfCharles Bankert
    • G01N27/26
    • A61B5/083A61B5/08A61B5/082A61B5/14539A61B5/682G01N33/497
    • Disclosed is a system and method for monitoring the breath chemistry of a patient's breath using a specially designed self-condensing sensor module mounted in a mask, nasal cannula, headband with boom apparatus, or similar device for directing the patients' breath towards the self-condensing sensor. Monitoring of a patient's breath pH provided by the miniaturized self-condensing pH sensor provides for real-time monitoring of patient airway pH values. The specially designed self-condensing sensor module incorporates a data transfer means, e.g. direct wiring or by providing a transmitter with an antenna for wireless transferring of the pH data to a processing receiver. The self-condensing pH sensor comprises a multi-tubular design with the outer tubular member housing a silver chloride reference element, an ion conducting path, and an antimony sensor plug isolated in an inner tubular member that is co-linearly or coaxially configured with the outer tubular member. A transmitter with an antenna transfers the observed pH data by employing one of many wireless methods, such as radio-frequency (RF) energy. Alternately, the transfer of observed pH data is accomplished by direct wire methods. The pH data is transferred or updated at specific intervals, which can be varied according to the patient's needs, to the processing receiver that is engaged to the treatment apparatus. In the therapeutic configuration, the processing receiver computes and diagnoses the breath chemistry data and determines at what frequency the treatment apparatus should be activated.
    • 公开了一种用于使用安装在面罩,鼻插管,带有吊杆装置的头带的专门设计的自冷凝传感器模块或类似装置来监测患者呼吸的呼吸化学的系统和方法, 冷凝传感器 监测由小型化自冷凝pH传感器提供的患者呼吸pH提供对患者气道pH值的实时监测。 专门设计的自会聚传感器模块包含数据传输装置,例如 直接布线或通过向发射机提供用于将pH数据无线传输到处理接收器的天线。 自冷凝pH传感器包括多管状设计,其中外部管状构件容纳氯化银参考元件,离子传导路径和隔离在内部管状构件中的锑传感器插塞,其与线性或同轴配置为 外管状构件。 具有天线的发射机通过采用诸如射频(RF)能量的许多无线方法之一来传送观察到的pH数据。 或者,观察到的pH数据的转移通过直接线法实现。 将pH数据以特定间隔传送或更新,其可以根据患者的需要而变化到接合到治疗设备的处理接收器。 在治疗配置中,处理接收器计算和诊断呼吸化学数据,并确定治疗装置应以什么频率被激活。
    • 5. 发明申请
    • Self-condensing pH sensor and catheter apparatus
    • US20060270940A1
    • 2006-11-30
    • US11137600
    • 2005-05-25
    • Ross TsukashimaErich WolfJeffery SchipperCharles BankertLeo RoucherThomas Wallner
    • Ross TsukashimaErich WolfJeffery SchipperCharles BankertLeo RoucherThomas Wallner
    • A61B5/08
    • A61B5/083A61B5/14539
    • The present invention is a system for monitoring a patient's breath chemistry comprising a plurality of components, including a self-condensing pH sensor distally mounted on a catheter, a transmitter with hydration sensing circuitry for the pH sensor, and processing receiver/data recorder. A specially designed self-condensing pH sensor is located on the distal end of a tubular catheter which is designed to be inserted into the patient's airway. Monitoring of a patient's breath pH is accomplished by using the miniaturized self-condensing pH sensor, providing for real-time monitoring of patient airway pH values. The self-condensing pH sensor comprises a multi-tubular design with the catheter tubular member housing a silver chloride reference element, an ion conducting path, and an antimony sensor element isolated within an inner tubular member that is co-linearly or coaxially configured with the outer catheter tubular member. A separation means may be employed in close proximity to the pH sensor to keep the pH sensor from direct mucosal contact along the wall of the patient's airway which could possibly affect the sensor's ability to accurately measure breath pH. Centimeter markings imprinted on the catheter body and an optional light source located near the distal tip of the catheter is used to aid in proper positioning. A transmitter with an antenna is engaged to the proximal end of the catheter and transfers the observed pH data by employing one of many wireless methods, such as radio-frequency (RF) energy. Alternately, the transfer of observed pH data is accomplished by direct wire methods. A processing receiver/data recorder receives the data and provides a means for storing and retrieving the data for study by a physician. The transmitter also includes a means to evaluate the signal strength of the sensor, which comprises of periodically sending a low voltage signal to the pH sensor and reviewing the resulting wave forms. The signal strength system can detect if the pH sensor is non-hydrated, partially hydrated, or fully hydrated. The pH data is transferred or updated at specific intervals, which can be varied according to the patient's needs, to the processing receiver/data recorder that can include an alarming means for predetermined pH values.
    • 6. 发明申请
    • Illumination means for catheter placement
    • 导管放置的照明手段
    • US20060266366A1
    • 2006-11-30
    • US11137619
    • 2005-05-25
    • Ross TsukashimaErich WolfJeffery SchipperCharles BankertLeo Roucher
    • Ross TsukashimaErich WolfJeffery SchipperCharles BankertLeo Roucher
    • A62B9/06A61M16/00
    • A61M16/0488A61B5/065A61B5/14539A61M16/0411
    • The present invention is a system comprising an illumination means and is mounted on a catheter wherein said illumination is generally located in the distal end of the catheter. Locating the illumination means near the distal end will simplify and facilitate precise placement of a measurement device in close proximity to the desired location. In one example, a catheter with a distally mounted pH sensor benefits from the use of an illumination means in the patient's airway such as in the oropharynx region. The illumination source of the present invention addresses catheter insertion and location using a continuous or flashing light emitting diode (LED) embedded in the distal end of the catheter to provide a visual sighting means for the physician. When the catheter, with the illumination means is inserted in the patient's airway, the illumination means functions to illuminate the distal end of the catheter and the anatomical features of the patient's airway for observation by the clinician, thereby facilitating proper placement of the measurement device.
    • 本发明是一种包括照明装置并且安装在导管上的系统,其中所述照明通常位于导管的远端。 在远端附近定位照明装置将简化和便于将测量装置精确放置在紧邻所需位置的位置。 在一个示例中,具有远端安装的pH传感器的导管受益于在患者的气道(例如口咽部)中使用照明装置。 本发明的照明源解决导管插入和使用嵌入在导管的远端中的连续或闪光的发光二极管(LED)的位置,以提供医生的视觉瞄准装置。 当将具有照明装置的导管插入患者的气道中时,照明装置用于照亮导管的远端和患者气道的解剖特征以供临床医生观察,从而便于测量装置的正确放置。
    • 8. 发明授权
    • Container for shipping and storing frozen products
    • 运输和储存冷冻产品的集装箱
    • US06381981B1
    • 2002-05-07
    • US09847902
    • 2001-05-02
    • Jerry YaddgoStephen KemmerrerCharles Bankert
    • Jerry YaddgoStephen KemmerrerCharles Bankert
    • F25D308
    • F25D3/125A61B50/00A61B2050/0014A61J1/165F25D3/08F25D2201/14F25D2303/082F25D2331/804
    • The present invention is directed to a container and method for shipping and storing frozen products. In particular, the present invention is directed to an insulated container for shipping and storing frozen tissue samples for an extended period of time, for example at least 72 hours. An exemplary embodiment of the container of the present invention includes a body having an open end and a product chamber lined with vacuum insulated panels, a spring assembly inside of the product chamber for supporting a lower cooling block and a stack of tissue packages (e.g. engineered tissue samples), and a lid assembly including one or more upper cooling blocks suspended therefrom. When the lid assembly is secured on the body of the container, the tissue packages are held in place between the upper and lower cooling blocks by the force of the spring assembly. The body of the container is dimensioned so that it may fit within an outer cardboard carton if desired for shipping.
    • 本发明涉及用于运输和储存冷冻产品的容器和方法。 特别地,本发明涉及用于长时间运送和储存冷冻组织样品的隔热容器,例如至少72小时。 本发明的容器的示例性实施例包括具有开口端的主体和衬有真空绝热面板的产品室,用于支撑下部冷却块的产品室内的弹簧组件和组织包装的堆叠(例如设计的 组织样本)和包括一个或多个从其悬挂的上部冷却块的盖组件。 当盖组件被固定在容器的主体上时,组织包装由弹簧组件的力保持在上部和下部冷却块之间的适当位置。 容器的主体的尺寸被设计成如果需要运输,它可以装配在外部纸板箱内。