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1. 发明授权

US08172082B2 Devices, systems and methods for medicament delivery 有权
标题翻译：用于药物输送的装置，系统和方法
公开(公告)号：US08172082B2
公开(公告)日：2012-05-08
申请号：US11671025
申请日：2007-02-05
申请人： Eric Shawn Edwards , Evan Thomas Edwards , Mark J. Licata , T. Spencer Williamson
发明人： Eric Shawn Edwards , Evan Thomas Edwards , Mark J. Licata , T. Spencer Williamson
IPC分类号： B65D85/72
CPC分类号： A61M5/19 , A61M5/2033 , A61M5/2053 , A61M5/2066 , A61M5/24 , A61M5/326 , A61M5/3287 , A61M2005/2026 , A61M2005/206 , A61M2005/2073 , A61M2039/1083 , A61M2039/1088 , A61M2205/13 , A61M2205/14 , A61M2205/18 , A61M2205/3576 , A61M2205/50 , A61M2205/502 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/6018 , A61M2205/6036 , G06F19/00 , G06F19/3468 , G16H20/17
摘要： An apparatus includes a container defining an internal region configured to contain multiple medicament delivery devices, such as, for example, pen injectors, auto-injectors, inhalers or the like. The container includes an electronic circuit system configured to output a first electronic output associated with a first medicament delivery device contained within the internal region when the first medicament delivery device is removed from the internal region of the container. The electronic circuit system is further configured to output a second electronic output associated with a second medicament delivery device contained within the internal region when the second medicament delivery device is removed from the internal region of the container. The second electronic output is different than the first electronic output. At least one of the first electronic output or the second electronic output is associated with a use instruction.
摘要翻译：一种装置包括限定内部区域的容器，该内部区域被配置为容纳多个药物输送装置，例如笔式注射器，自动注射器，吸入器等。容器包括电子电路系统，该电子电路系统被配置为当第一药物输送装置从容器的内部区域移除时，输出与包含在内部区域内的第一药物输送装置相关联的第一电子输出。电子电路系统还被配置为当第二药物输送装置从容器的内部区域移除时，输出与包含在内部区域内的第二药物输送装置相关联的第二电子输出。第二个电子输出与第一个电子输出不同。第一电子输出或第二电子输出中的至少一个与使用指令相关联。

2. 发明授权

US08544645B2 Devices, systems and methods for medicament delivery 有权
标题翻译：用于药物输送的装置，系统和方法
公开(公告)号：US08544645B2
公开(公告)日：2013-10-01
申请号：US13464234
申请日：2012-05-04
申请人： Eric Shawn Edwards , Evan Thomas Edwards , Mark J. Licata , T. Spencer Williamson
发明人： Eric Shawn Edwards , Evan Thomas Edwards , Mark J. Licata , T. Spencer Williamson
IPC分类号： B65D83/10
CPC分类号： A61M5/19 , A61M5/2033 , A61M5/2053 , A61M5/2066 , A61M5/24 , A61M5/326 , A61M5/3287 , A61M2005/2026 , A61M2005/206 , A61M2005/2073 , A61M2039/1083 , A61M2039/1088 , A61M2205/13 , A61M2205/14 , A61M2205/18 , A61M2205/3576 , A61M2205/50 , A61M2205/502 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/6018 , A61M2205/6036 , G06F19/00 , G06F19/3468 , G16H20/17
摘要： An apparatus includes a container defining an internal region configured to contain multiple medicament delivery devices, such as, for example, pen injectors, auto-injectors, inhalers or the like. The container includes an electronic circuit system configured to output a first electronic output associated with a first medicament delivery device contained within the internal region when the first medicament delivery device is removed from the internal region of the container. The electronic circuit system is further configured to output a second electronic output associated with a second medicament delivery device contained within the internal region when the second medicament delivery device is removed from the internal region of the container. The second electronic output is different than the first electronic output. At least one of the first electronic output or the second electronic output is associated with a use instruction.
摘要翻译：一种装置包括限定内部区域的容器，该内部区域被配置为容纳多个药物输送装置，例如笔式注射器，自动注射器，吸入器等。容器包括电子电路系统，该电子电路系统被配置为当第一药物输送装置从容器的内部区域移除时，输出与包含在内部区域内的第一药物输送装置相关联的第一电子输出。电子电路系统还被配置为当第二药物输送装置从容器的内部区域移除时，输出与包含在内部区域内的第二药物输送装置相关联的第二电子输出。第二个电子输出与第一个电子输出不同。第一电子输出或第二电子输出中的至少一个与使用指令相关联。

3. 发明授权

US08926594B2 Devices, systems and methods for medicament delivery 有权
标题翻译：用于药物输送的装置，系统和方法
公开(公告)号：US08926594B2
公开(公告)日：2015-01-06
申请号：US13404699
申请日：2012-02-24
申请人： Eric Shawn Edwards , Evan Thomas Edwards , Mark J. Licata , Paul F. Meyers , David A. Weinzierl
发明人： Eric Shawn Edwards , Evan Thomas Edwards , Mark J. Licata , Paul F. Meyers , David A. Weinzierl
IPC分类号： A61K9/22 , A61M5/20 , A61M5/142 , A61M5/19 , A61M5/31 , A61M5/32 , A61M15/00
CPC分类号： A61M15/009 , A61M5/14244 , A61M5/19 , A61M5/2033 , A61M5/2053 , A61M5/3129 , A61M5/3202 , A61M5/3204 , A61M5/3234 , A61M5/326 , A61M5/3287 , A61M5/5086 , A61M35/00 , A61M2005/206 , A61M2005/2073 , A61M2205/50 , A61M2205/502 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/587 , A61M2205/8206 , G06F19/00 , G06F19/3456
摘要： An apparatus includes a label configured to be coupled to a medicament delivery device. The label includes a first surface and a second surface. The first surface is configured to be coupled to an outer surface of the medicament delivery device. The second surface includes a textual indicia. The label further includes an electronic circuit system configured to output an electronic signal.
摘要翻译：一种装置包括被配置为联接到药物输送装置的标签。标签包括第一表面和第二表面。第一表面被配置为联接到药物输送装置的外表面。第二个表面包括文字标记。标签还包括被配置为输出电子信号的电子电路系统。

4. 发明授权

US07918823B2 Devices, systems and methods for medicament delivery 有权
标题翻译：用于药物输送的装置，系统和方法
公开(公告)号：US07918823B2
公开(公告)日：2011-04-05
申请号：US12688314
申请日：2010-01-15
申请人： Eric Shawn Edwards , Evan Thomas Edwards , Mark J. Licata , Paul F. Meyers
发明人： Eric Shawn Edwards , Evan Thomas Edwards , Mark J. Licata , Paul F. Meyers
IPC分类号： A61M37/00
CPC分类号： A61M5/2033 , A61M5/19 , A61M5/2046 , A61M5/2053 , A61M5/24 , A61M5/2459 , A61M5/3129 , A61M5/31565 , A61M5/31591 , A61M5/3202 , A61M5/3204 , A61M5/326 , A61M2005/2013 , A61M2005/206 , A61M2005/2073 , A61M2205/14 , A61M2205/3576 , A61M2205/50 , A61M2205/502 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/6018 , A61M2205/6036 , A61M2207/00 , B65B3/003 , B65B55/02 , G06F19/00 , G06F19/3468
摘要： Apparatuses for automatic medicament injection and methods for manufacturing automatic medicament injectors are described herein. In some embodiments, an apparatus includes a housing, a needle, an energy storage member, an actuator, a locking member, and a needle guard. The needle is configured to move between a first position and a second position. In its first position, the needle is contained within the housing. In its second position, at least a portion of the needle extends from the housing. The energy storage member has a first configuration and a second configuration and is configured to produce a force when moving between its first configuration and its second configuration to move the needle from its first position to its second position. The actuator is configured to move the energy storage member from its first configuration to its second configuration. The locking member is movably coupled to the distal end portion of the housing such that the locking member can be moved between a first position and a second position. In its first position, the locking member is configured to engage the actuator to prevent the actuator from moving the energy storage member to the second configuration. The needle guard is removably coupled to at least one of the distal end portion of the housing or a base movably coupled to the distal end portion of the housing.
摘要翻译：本文描述了用于自动药物注射的装置和用于制造自动药物注射器的方法。在一些实施例中，装置包括壳体，针，能量存储构件，致动器，锁定构件和针护罩。针构造成在第一位置和第二位置之间移动。在其第一位置，针被容纳在壳体内。在其第二位置，针的至少一部分从壳体延伸。能量存储构件具有第一构造和第二构造，并且构造成在其第一构型和其第二构造之间移动时产生力以将针从其第一位置移动到其第二位置。致动器被配置为将能量存储构件从其第一构造移动到其第二构造。锁定构件可移动地联接到壳体的远端部分，使得锁定构件能够在第一位置和第二位置之间移动。在其第一位置，锁定构件构造成接合致动器以防止致动器将能量存储构件移动到第二构造。针护罩可移除地联接到壳体的远端部分中的至少一个或可移动地联接到壳体的远端部分的基座。

5. 发明授权

US08920367B2 Devices, systems and methods for medicament delivery 有权
标题翻译：用于药物输送的装置，系统和方法
公开(公告)号：US08920367B2
公开(公告)日：2014-12-30
申请号：US13326959
申请日：2011-12-15
申请人： Eric Shawn Edwards , Evan Thomas Edwards , Mark J. Licata , Paul F. Meyers
发明人： Eric Shawn Edwards , Evan Thomas Edwards , Mark J. Licata , Paul F. Meyers
IPC分类号： A61M37/00 , A61M5/20 , A61M5/19 , G06F19/00 , A61M5/32 , A61M39/10 , A61M5/24
CPC分类号： A61M5/19 , A61M5/2033 , A61M5/2053 , A61M5/2066 , A61M5/24 , A61M5/326 , A61M5/3287 , A61M2005/2026 , A61M2005/206 , A61M2005/2073 , A61M2039/1083 , A61M2039/1088 , A61M2205/13 , A61M2205/14 , A61M2205/18 , A61M2205/3576 , A61M2205/50 , A61M2205/502 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/6018 , A61M2205/6036 , G06F19/00 , G06F19/3468 , G16H20/17
摘要： An apparatus includes a medicament container assembly, a movable assembly, and a spring. The medicament container assembly includes a first plunger defining a first volume, and a second plunger defining a second volume. The movable assembly includes a first movable member and a second movable member. The second movable member can move the second plunger within the medicament container assembly. The first movable member can move the first plunger in a first direction within the medicament container assembly to expel a contents of at least the first volume via a needle. The spring is configured to urge the needle in a second direction. The release portion of the first movable member is configured to contact the second movable member after the first movable member moves the first plunger to enable the spring to move the needle in the second direction.
摘要翻译：一种装置包括药物容器组件，可移动组件和弹簧。药物容器组件包括限定第一容积的第一柱塞和限定第二体积的第二柱塞。可移动组件包括第一可动构件和第二可移动构件。第二可移动部件可以将药剂容器组件内的第二柱塞移动。第一可移动部件可以在药物容器组件内沿第一方向移动第一柱塞，以经由针排出至少第一体积的内容物。弹簧构造成在第二方向上推动针。第一可动构件的释放部分构造成在第一可动构件移动第一柱塞之后接触第二可动构件，以使弹簧能够沿第二方向移动针。

6. 发明授权

US08123719B2 Devices, systems and methods for medicament delivery 有权
标题翻译：用于药物输送的装置，系统和方法
公开(公告)号：US08123719B2
公开(公告)日：2012-02-28
申请号：US11692359
申请日：2007-03-28
申请人： Eric Shawn Edwards , Evan Thomas Edwards , Mark J. Licata , Paul F. Meyers
发明人： Eric Shawn Edwards , Evan Thomas Edwards , Mark J. Licata , Paul F. Meyers
IPC分类号： A61M37/00
CPC分类号： A61M5/19 , A61M5/2033 , A61M5/2053 , A61M5/2066 , A61M5/24 , A61M5/326 , A61M5/3287 , A61M2005/2026 , A61M2005/206 , A61M2005/2073 , A61M2039/1083 , A61M2039/1088 , A61M2205/13 , A61M2205/14 , A61M2205/18 , A61M2205/3576 , A61M2205/50 , A61M2205/502 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/6018 , A61M2205/6036 , G06F19/00 , G06F19/3468 , G16H20/17
摘要： An apparatus includes a housing, a medicament container disposed within the housing, a first energy storage member and second energy storage member. The medicament container includes a first plunger disposed within a proximal end portion of the medicament container and a second plunger disposed within the medicament container spaced apart from the first plunger. The first energy storage member is configured to produce a force when actuated to move at least the second plunger within the medicament container. The second energy storage member is configured to produce a force when actuated to move the first plunger and the second plunger within the medicament container. The second energy storage member is different than the first energy storage member.
摘要翻译：一种装置包括壳体，设置在壳体内的药物容器，第一能量存储构件和第二能量存储构件。药物容器包括设置在药物容器的近端部分内的第一柱塞和设置在与第一柱塞间隔开的药物容器内的第二柱塞。第一能量存储构件被配置为当被致动时产生至少第二柱塞在药物容器内移动的力。第二能量存储构件被配置为当被致动以在药物容器内移动第一柱塞和第二柱塞时产生力。第二能量存储部件与第一能量存储部件不同。

7. 发明授权

US07648482B2 Devices, systems, and methods for medicament delivery 有权
标题翻译：用于药物输送的装置，系统和方法
公开(公告)号：US07648482B2
公开(公告)日：2010-01-19
申请号：US11562061
申请日：2006-11-21
申请人： Evan Thomas Edwards , Eric Shawn Edwards , Mark J. Licata
发明人： Evan Thomas Edwards , Eric Shawn Edwards , Mark J. Licata
IPC分类号： A61M5/20
CPC分类号： A61M5/19 , A61M5/2033 , A61M5/2053 , A61M5/24 , A61M5/3204 , A61M5/326 , A61M2005/2013 , A61M2005/206 , A61M2005/2073 , A61M2205/14 , A61M2205/3576 , A61M2205/50 , A61M2205/502 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/6018 , A61M2205/6036 , G06F19/00 , G06F19/3468
摘要： An apparatus includes a housing, a medicament container and an actuator. The actuator includes a release member and an energy storage member having a first position and a second position. In the first position, the energy storage member has a first potential energy. In the second position the energy storage member has a second potential energy. The energy storage member is configured to convert a portion of the first potential energy into kinetic energy when moved from the first position to the second position to move the medicament container within the housing. The energy storage member has a longitudinal axis offset from a longitudinal axis of the medicament container. The release member is configured to selectively deploy the energy storage member from its first position to its second position.
摘要翻译：一种装置包括壳体，药物容器和致动器。致动器包括释放构件和具有第一位置和第二位置的能量存储构件。在第一位置，能量存储构件具有第一势能。在第二位置，能量存储构件具有第二势能。能量存储构件被构造成当从第一位置移动到第二位置时将第一势能的一部分转换成动能，以使药物容器在壳体内移动。能量存储构件具有从药物容器的纵向轴线偏离的纵向轴线。释放构件被构造成将能量存储构件从其第一位置选择性地展开到其第二位置。

8. 发明申请

US20120116318A1 DEVICES, SYSTEMS AND METHODS FOR MEDICAMENT DELIVERY 有权
标题翻译：用于药物递送的装置，系统和方法
公开(公告)号：US20120116318A1
公开(公告)日：2012-05-10
申请号：US13326959
申请日：2011-12-15
申请人： Eric Shawn Edwards , Evan Thomas Edwards , Mark J. Licata , Paul F. Meyers
发明人： Eric Shawn Edwards , Evan Thomas Edwards , Mark J. Licata , Paul F. Meyers
IPC分类号： A61M5/315 , A61M5/31
CPC分类号： A61M5/19 , A61M5/2033 , A61M5/2053 , A61M5/2066 , A61M5/24 , A61M5/326 , A61M5/3287 , A61M2005/2026 , A61M2005/206 , A61M2005/2073 , A61M2039/1083 , A61M2039/1088 , A61M2205/13 , A61M2205/14 , A61M2205/18 , A61M2205/3576 , A61M2205/50 , A61M2205/502 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/6018 , A61M2205/6036 , G06F19/00 , G06F19/3468 , G16H20/17
摘要： An apparatus includes a housing and a medicament container disposed within the housing. The medicament container includes a first plunger and a second plunger, each disposed therein. The medicament container has a first configuration and a second configuration. In the first configuration, the first plunger is disposed in a first position and the second plunger is disposed in a second position spaced apart from the first position by a first distance. Accordingly, a first portion is defined between the first plunger and the second plunger. A second portion is defined between the second plunger and a distal end of the medicament container. In the second configuration, the first plunger remains in the first position and the second plunger is disposed in a third position spaced apart from the first position by a second distance, such that a volume of the second portion is greater when the medicament container is in the second configuration than when in the first configuration.
摘要翻译：一种装置包括壳体和设置在壳体内的药物容器。药物容器包括每个设置在其中的第一柱塞和第二柱塞。药物容器具有第一构造和第二构造。在第一构造中，第一柱塞设置在第一位置，并且第二柱塞设置在与第一位置间隔开第一距离的第二位置。因此，第一部分被限定在第一柱塞和第二柱塞之间。第二部分被限定在第二柱塞和药物容器的远端之间。在第二构造中，第一柱塞保持在第一位置，第二柱塞设置在与第一位置隔开第二距离的第三位置，使得当药物容器处于第二位置时第二部分的体积更大第二种配置比在第一种配置时。

9. 发明授权

US07648483B2 Devices, systems and methods for medicament delivery 有权
标题翻译：用于药物输送的装置，系统和方法
公开(公告)号：US07648483B2
公开(公告)日：2010-01-19
申请号：US11758393
申请日：2007-06-05
申请人： Eric Shawn Edwards , Evan Thomas Edwards , Mark J. Licata , Paul F. Meyers
发明人： Eric Shawn Edwards , Evan Thomas Edwards , Mark J. Licata , Paul F. Meyers
IPC分类号： A61M37/00
CPC分类号： A61M5/2033 , A61M5/19 , A61M5/2046 , A61M5/2053 , A61M5/24 , A61M5/2459 , A61M5/3129 , A61M5/31565 , A61M5/31591 , A61M5/3202 , A61M5/3204 , A61M5/326 , A61M2005/2013 , A61M2005/206 , A61M2005/2073 , A61M2205/14 , A61M2205/3576 , A61M2205/50 , A61M2205/502 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/6018 , A61M2205/6036 , A61M2207/00 , B65B3/003 , B65B55/02 , G06F19/00 , G06F19/3468
摘要： Apparatuses for automatic medicament injection and methods for manufacturing automatic medicament injectors are described herein. In some embodiments, an apparatus includes a housing, a needle, an energy storage member, an actuator, a locking member, and a needle guard. The needle is configured to move between a first position and a second position. In its first position, the needle is contained within the housing. In its second position, at least a portion of the needle extends from the housing. The energy storage member has a first configuration and a second configuration and is configured to produce a force when moving between its first configuration and its second configuration to move the needle from its first position to its second position. The actuator is configured to move the energy storage member from its first configuration to its second configuration. The locking member is movably coupled to the distal end portion of the housing such that the locking member can be moved between a first position and a second position. In its first position, the locking member is configured to engage the actuator to prevent the actuator from moving the energy storage member to the second configuration. The needle guard is removably coupled to at least one of the distal end portion of the housing or a base movably coupled to the distal end portion of the housing.
摘要翻译：本文描述了用于自动药物注射的装置和用于制造自动药物注射器的方法。在一些实施例中，装置包括壳体，针，能量存储构件，致动器，锁定构件和针护罩。针构造成在第一位置和第二位置之间移动。在其第一位置，针被容纳在壳体内。在其第二位置，针的至少一部分从壳体延伸。能量存储构件具有第一构造和第二构造，并且构造成在其第一构型和其第二构造之间移动时产生力以将针从其第一位置移动到其第二位置。致动器被配置为将能量存储构件从其第一构造移动到其第二构造。锁定构件可移动地联接到壳体的远端部分，使得锁定构件能够在第一位置和第二位置之间移动。在其第一位置，锁定构件构造成接合致动器以防止致动器将能量存储构件移动到第二构造。针护罩可移除地联接到壳体的远端部分中的至少一个或可移动地联接到壳体的远端部分的基座。

10. 发明授权

US08608698B2 Devices, systems and methods for medicament delivery 有权
公开(公告)号：US08608698B2
公开(公告)日：2013-12-17
申请号：US13053451
申请日：2011-03-22
申请人： Eric Shawn Edwards , Evan Thomas Edwards , Mark J. Licata , Paul F. Meyers
发明人： Eric Shawn Edwards , Evan Thomas Edwards , Mark J. Licata , Paul F. Meyers
IPC分类号： A61M37/00
CPC分类号： A61M5/2033 , A61M5/19 , A61M5/2046 , A61M5/2053 , A61M5/24 , A61M5/2459 , A61M5/3129 , A61M5/31565 , A61M5/31591 , A61M5/3202 , A61M5/3204 , A61M5/326 , A61M2005/2013 , A61M2005/206 , A61M2005/2073 , A61M2205/14 , A61M2205/3576 , A61M2205/50 , A61M2205/502 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/6018 , A61M2205/6036 , A61M2207/00 , B65B3/003 , B65B55/02 , G06F19/00 , G06F19/3468
摘要： An apparatus includes a housing, a needle, a first energy storage member and a second energy storage member. The needle is movably disposed within the housing and is configured to be to be placed in fluid communication with a medicament container. The needle is configured to move between a first position and a second position. In its first position, the needle is contained within the housing. In its second position, at least a portion of the needle extends from the housing. The first energy storage member is disposed within the housing, and is configured to produce a first force when actuated. The second energy storage member is disposed within the housing, and is configured to be actuated in response to the first force to produce a second force to move the needle from the first needle position to the second needle position.

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