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1. 发明授权

US5860991A Method for the percutaneous suturing of a vascular puncture site 失效
标题翻译：血管穿刺部位经皮缝合方法
公开(公告)号：US5860991A
公开(公告)日：1999-01-19
申请号：US916353
申请日：1997-08-22
申请人： Enrique J. Klein , T. Daniel Gross , Tomoaki Hinohara , James W. Vetter
发明人： Enrique J. Klein , T. Daniel Gross , Tomoaki Hinohara , James W. Vetter
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/12 , A61F2/00
CPC分类号： A61B17/0625 , A61B17/0057 , A61B17/0469 , A61B17/0401 , A61B17/0482 , A61B17/06066 , A61B2017/00004 , A61B2017/00637 , A61B2017/00641 , A61B2017/00663 , A61B2017/00867 , A61B2017/0458 , A61B2017/0464 , A61B2017/047 , A61B2017/0472 , A61B2017/0474 , A61B2017/06057 , A61F2002/30093 , A61F2210/0019 , Y10S604/90
摘要： A suture applying device comprises a shaft which carries a pair of needles near its distal end. The needles are joined by a length of suture, and the shaft is used to both introduce the needles into a lumen of a body structure and to push the needles back through tissue on either side of the puncture site. After the needles have passed through the tissue, they are captured on the shaft and drawn outward through the tract, leaving a loop of suture behind to close the puncture site near the body lumen. The suture can then be tied and the knot pushed back through the tract to complete the closure. Alternatively, a locking fastener formed of a resorbable material can be placed into the penetration over the sutures and the sutures tied over the fastener.
摘要翻译：缝合施加装置包括在其远端附近承载一对针的轴。针通过一定长度的缝合线连接，并且该轴用于将针引入体结构的内腔并将针推回穿刺部位两侧的组织。针穿过组织后，它们被捕获在轴上并向外穿过管道，留下一条缝合线，以闭合身体内腔附近的穿刺部位。然后可以将缝合线缝合，并将结通过管道推回以完成闭合。或者，由可再吸收材料形成的锁定紧固件可以被放置在缝合线上的穿透物中，并且缝合线被绑在紧固件上。

2. 发明授权

US5417699A Device and method for the percutaneous suturing of a vascular puncture site 失效
标题翻译：用于经皮缝合血管穿刺部位的装置和方法
公开(公告)号：US5417699A
公开(公告)日：1995-05-23
申请号：US989611
申请日：1992-12-10
申请人： Enrique J. Klein , T. Daniel Gross , Tomoaki Hinohara , James W. Vetter
发明人： Enrique J. Klein , T. Daniel Gross , Tomoaki Hinohara , James W. Vetter
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/12 , A61F2/00
CPC分类号： A61B17/0625 , A61B17/0057 , A61B17/0469 , A61B17/0401 , A61B17/0482 , A61B17/06066 , A61B2017/00004 , A61B2017/00637 , A61B2017/00641 , A61B2017/00663 , A61B2017/00867 , A61B2017/0458 , A61B2017/0464 , A61B2017/047 , A61B2017/0472 , A61B2017/0474 , A61B2017/06057 , A61F2002/30093 , A61F2210/0019 , Y10S604/90
摘要： A suture applying device comprises a shaft which carries a pair of needles near its distal end. The needles are joined by a length of suture, and the shaft is used to both introduce the needles into a lumen of a body structure and to push the needles back through tissue on either side of the puncture site. After the needles have passed through the tissue, they are captured on the shaft and drawn outward through the tract, leaving a loop of suture behind to close the puncture site near the body lumen. The suture can then be tied and the knot pushed back through the tract to complete the closure. Alternatively, a locking fastener formed of a resorbable material can be placed into the penetration over the sutures and the sutures tied over the fastener.
摘要翻译：缝合施加装置包括在其远端附近承载一对针的轴。针通过一定长度的缝合线连接，并且该轴用于将针引入体结构的内腔并将针推回穿刺部位两侧的组织。针穿过组织后，它们被捕获在轴上并向外穿过管道，留下一条缝合线，以闭合身体内腔附近的穿刺部位。然后可以将缝合线缝合，并将结通过管道推回以完成闭合。或者，由可再吸收材料形成的锁定紧固件可以被放置在缝合线上的穿透物中，并且缝合线被绑在紧固件上。

3. 发明授权

US07445626B2 Device and method for suturing tissue 失效
标题翻译：用于缝合组织的装置和方法
公开(公告)号：US07445626B2
公开(公告)日：2008-11-04
申请号：US10737668
申请日：2003-12-16
申请人： Ronald W. Songer , James W. Vetter , Enrique J. Klein , Bernard A. Andreas , Michael Barrett , Mark J. Foley , Brian Gore , Lewis Isbell , T. Daniel Gross , Tomoaki Hinohara
发明人： Ronald W. Songer , James W. Vetter , Enrique J. Klein , Bernard A. Andreas , Michael Barrett , Mark J. Foley , Brian Gore , Lewis Isbell , T. Daniel Gross , Tomoaki Hinohara
IPC分类号： A61B17/06
CPC分类号： A61B17/11 , A61B17/0057 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/06066 , A61B17/3417 , A61B17/3421 , A61B2017/00004 , A61B2017/00637 , A61B2017/00641 , A61B2017/00663 , A61B2017/00867 , A61B2017/0458 , A61B2017/0464 , A61B2017/047 , A61B2017/0472 , A61B2017/0474 , A61B2017/0496 , A61B2017/06057 , A61F2002/30093 , A61F2210/0019
摘要： Systems for suturing a tissue layer having two sides with a suture be releasably retaining at least a portion of the suture in a stationary position on one side of the tissue layer. The portion of the suture is retrieved through the tissue layer from the opposite side whereby the suture is drawn from one side to the opposite side. Systems for suturing the wall of a tubular graft having two sides is also provided using a suture by releasably retaining at least a portion of the suture on one side of the wall. the portion of the length of suture is retrieved through the wall of the graft to the opposite side of the wall.
摘要翻译：通过可靠地将至少一部分缝合线保持在组织层的一侧上的静止位置来提供用于用缝合线缝合具有两侧的组织层的系统。缝线的部分从相对侧通过组织层回收，由此将缝合线从一侧拉到相对侧。也可以使用缝合线通过可释放地将缝合线的至少一部分保持在壁的一侧上来缝合具有两侧的管状移植物的壁的系统。缝合长度的一部分通过移植物的壁回收到壁的相对侧。

4. 发明授权

US5779719A Device and method for the percutaneous suturing of a vascular puncture site 失效
公开(公告)号：US5779719A
公开(公告)日：1998-07-14
申请号：US259410
申请日：1994-06-14
申请人： Enrique J. Klein , T. Daniel Gross , Tomoaki Hinohara , James W. Vetter
发明人： Enrique J. Klein , T. Daniel Gross , Tomoaki Hinohara , James W. Vetter
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/12 , A61F2/00
CPC分类号： A61B17/0625 , A61B17/0057 , A61B17/0469 , A61B17/0401 , A61B17/0482 , A61B17/06066 , A61B2017/00004 , A61B2017/00637 , A61B2017/00641 , A61B2017/00663 , A61B2017/00867 , A61B2017/0458 , A61B2017/0464 , A61B2017/047 , A61B2017/0472 , A61B2017/0474 , A61B2017/06057 , A61F2002/30093 , A61F2210/0019 , Y10S604/90
摘要： A suture applying device comprises a shaft which carries a pair of needles near its distal end. The needles are joined by a length of suture, and the shaft is used to both introduce the needles into a lumen of a body structure and to push the needles back through tissue on either side of the puncture site. After the needles have passed through the tissue, they are captured on the shaft and drawn outward through the tract, leaving a loop of suture behind to close the puncture site near the body lumen. The suture can then be tied and the knot pushed back through the tract to complete the closure. Alternatively, a locking fastener formed of a resorbable material can be placed into the penetration over the sutures and the sutures tied over the fastener.

5. 发明授权

US5613974A Apparatus and method for vascular closure 失效
标题翻译：用于血管闭合的装置和方法
公开(公告)号：US5613974A
公开(公告)日：1997-03-25
申请号：US252124
申请日：1994-06-01
申请人： Bernard H. Andreas , T. Daniel Gross , Tomoaki Hinohara , James W. Vetter
发明人： Bernard H. Andreas , T. Daniel Gross , Tomoaki Hinohara , James W. Vetter
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/12 , A61F2/00
CPC分类号： A61B17/0625 , A61B17/0057 , A61B17/0469 , A61B17/0401 , A61B17/0482 , A61B17/06066 , A61B2017/00004 , A61B2017/00637 , A61B2017/00641 , A61B2017/00663 , A61B2017/00867 , A61B2017/0458 , A61B2017/0464 , A61B2017/047 , A61B2017/0472 , A61B2017/0474 , A61B2017/06057 , A61F2002/30093 , A61F2210/0019 , Y10S604/90
摘要： A suture-applying device comprises a guide body having a needle guide at its distal end. Needles are reciprocatably carried on a shaft so that they may be advanced through the needle guide and tissue into the guide body. The suturing device is used by placing the needle guide within a vascular puncture. A contact surface is provided on the guide body, and the needle guide is configured so that the vascular wall surrounding the puncture is fully exposed to the needles passing therethrough. The suturing device may be combined with a predilator to form a system for suturing vascular punctures.
摘要翻译：缝合施加装置包括在其远端具有针引导件的引导体。针可以可往复运动地携带在轴上，使得它们可以通过针引导件和组织推进到引导体中。通过将针引导件放置在血管穿刺中来使用缝合装置。接触表面设置在引导体上，针引导构造成使得围绕穿刺的血管壁完全暴露于穿过其中的针。缝合装置可以与预制器组合以形成用于缝合血管穿刺的系统。

6. 发明授权

US08398656B2 Clip applier and methods of use 有权
标题翻译：夹子施放器和使用方法
公开(公告)号：US08398656B2
公开(公告)日：2013-03-19
申请号：US13039087
申请日：2011-03-02
申请人： Thomas J. Palermo , William M. Belef , Michael T. Carley , Richard S. Ginn , Anthony J. Pantages , Ronald J. Jabba , Brian A. Ellingwood , Laveille Kao Voss , Kelly J. McCrystle , T. Daniel Gross , Arkady Kokish
发明人： Thomas J. Palermo , William M. Belef , Michael T. Carley , Richard S. Ginn , Anthony J. Pantages , Ronald J. Jabba , Brian A. Ellingwood , Laveille Kao Voss , Kelly J. McCrystle , T. Daniel Gross , Arkady Kokish
IPC分类号： A61B17/08 , A61B17/10
CPC分类号： A61B17/0057 , A61B17/064 , A61B17/0644 , A61B17/068 , A61B17/10 , A61B17/1227 , A61B2017/0003 , A61B2017/00106 , A61B2017/00349 , A61B2017/00637 , A61B2017/00668 , A61B2017/00672 , A61B2017/0649 , A61B2017/12018 , A61B2090/065
摘要： An apparatus for delivering a closure element can include a splittable carrier tube and a splitter to split the tube. The carrier tube can have an outer surface retaining a closure element in a tubular configuration and can be split into radially-expandable flaps. A closure element can have a shape-memory body having a relaxed configuration with a planar-annular body defining a lumen with tines directed inwardly from the body. The clip can be held in a retaining configuration having a substantially asymmetrically-elongated tubular shape with a trapezoidal longitudinal cross-sectional profile and a proximal end having the tines being longitudinally directed with a first tine being more distally oriented compared to a substantially opposite second tine being more proximal, and retracting to a deploying configuration having a tubular shape with a rectangular longitudinal cross-sectional profile with the first tine being even with the second tine when being delivered.
摘要翻译：用于传送闭合元件的装置可以包括可拆卸的载体管和用于分裂管的分离器。载体管可以具有将封闭元件保持为管状构造的外表面，并且可以被分割成径向可膨胀的瓣。封闭元件可以具有形状记忆体，该形状记忆体具有松弛构型，其中平面环形主体限定具有从身体向内指向的尖齿的内腔。夹具可以保持在具有梯形纵截面轮廓的基本上不对称的细长管状形状的保持构造中，并且具有尖端的尖端与第一齿纵向对准，该第一齿与基本上相对的第二齿相比更向远侧取向更靠近并且缩回到具有矩形纵向截面轮廓的管状形状的展开构造，其中第一齿在被递送时与第二齿均匀。

7. 发明申请

US20110230897A1 CLIP APPLIER AND METHODS OF USE 有权
标题翻译：夹具应用和使用方法
公开(公告)号：US20110230897A1
公开(公告)日：2011-09-22
申请号：US13039087
申请日：2011-03-02
申请人： Thomas J. Palermo , William M. Belef , Michael T. Carley , Richard S. Ginn , Anthony J. Pantages , Ronald J. Jabba , Brian A. Ellingwood , Laveille Kao Voss , Kelly J. McCrystle , T. Daniel Gross , Arkady Kokish
发明人： Thomas J. Palermo , William M. Belef , Michael T. Carley , Richard S. Ginn , Anthony J. Pantages , Ronald J. Jabba , Brian A. Ellingwood , Laveille Kao Voss , Kelly J. McCrystle , T. Daniel Gross , Arkady Kokish
IPC分类号： A61B17/10
CPC分类号： A61B17/0057 , A61B17/064 , A61B17/0644 , A61B17/068 , A61B17/10 , A61B17/1227 , A61B2017/0003 , A61B2017/00106 , A61B2017/00349 , A61B2017/00637 , A61B2017/00668 , A61B2017/00672 , A61B2017/0649 , A61B2017/12018 , A61B2090/065
摘要： An apparatus for delivering a closure element can include a splittable carrier tube and a splitter to split the tube. The carrier tube can have an outer surface retaining a closure element in a tubular configuration and can be split into radially-expandable flaps. A closure element can have a shape-memory body having a relaxed configuration with a planar-annular body defining a lumen with tines directed inwardly from the body. The clip can be held in a retaining configuration having a substantially asymmetrically-elongated tubular shape with a trapezoidal longitudinal cross-sectional profile and a proximal end having the tines being longitudinally directed with a first tine being more distally oriented compared to a substantially opposite second tine being more proximal, and retracting to a deploying configuration having a tubular shape with a rectangular longitudinal cross-sectional profile with the first tine being even with the second tine when being delivered.
摘要翻译：用于传送闭合元件的装置可以包括可拆卸的载体管和用于分裂管的分离器。载体管可以具有将封闭元件保持为管状构造的外表面，并且可以被分割成径向可膨胀的瓣。封闭元件可以具有形状记忆体，该形状记忆体具有松弛构型，其中平面环形主体限定具有从身体向内指向的尖齿的内腔。夹具可以保持在具有梯形纵截面轮廓的基本上不对称的细长管状形状的保持构造中，并且具有尖端的尖端与第一齿纵向对准，该第一齿与基本上相对的第二齿相比更向远侧取向更靠近并且缩回到具有矩形纵向截面轮廓的管状形状的展开构造，其中第一齿在被递送时与第二齿均匀。

8. 发明授权

US07147646B2 Snared suture trimmer 有权
公开(公告)号：US07147646B2
公开(公告)日：2006-12-12
申请号：US10860443
申请日：2004-06-03
申请人： Mike Dana , Rob George , T. Daniel Gross , Maurice Marthaler , Dawn Ma , Jim Swett
发明人： Mike Dana , Rob George , T. Daniel Gross , Maurice Marthaler , Dawn Ma , Jim Swett
IPC分类号： A61B17/04
CPC分类号： A61B17/0467 , A61B17/0057 , A61B17/0485 , A61B2017/00663 , A61B2017/0474 , G06F17/16
摘要： A suture trimmer, the suture trimmer including a shaft having a first end, a second end and a bore extending axially therebetween, the shaft having an opening formed in the side adjacent the distal end. A fitting is on the distal end of the shaft, the fitting having an aperture formed therethrough, the aperture axially aligned with the bore of the lumen and in communication with the opening formed in the shaft. The suture trimmer further including a actuating device, the actuating device coupled to a cutting member slidably disposed within the bore of the shaft, the cutting member configured to be moved between a first position and a second position, when disposed in the second position the cutting member closes the opening formed in the side of the shaft.

9. 发明申请

US20110071567A1 ARTICULATING SUTURING AND DEVICE AND METHOD 审中-公开
标题翻译：实践和设备及方法
公开(公告)号：US20110071567A1
公开(公告)日：2011-03-24
申请号：US12955848
申请日：2010-11-29
申请人： D. Bruce Modesitt , Justina A. Franco , T. Daniel Gross
发明人： D. Bruce Modesitt , Justina A. Franco , T. Daniel Gross
IPC分类号： A61B17/04
CPC分类号： A61B17/0625 , A61B17/0057 , A61B17/0469 , A61B17/0482 , A61B17/0483 , A61B2017/00637 , A61B2017/00641 , A61B2017/00663 , A61B2017/00672 , A61B2017/047 , A61B2017/0472 , A61B2017/0477 , A61B2017/0496 , A61B2017/06057 , A61B2017/2927
摘要： Devices, systems, and methods for suturing of body lumens allow the suturing of vascular puncture sites located at the distal end of a percutaneous tissue tract. An elongated articulated foot near a distal end of a shaft is inserted through the penetration and actuated so that the foot extends along the lumenal axis. The foot carries suturing attachment cuffs, and needles are advanced from the shaft through the vessel wall outside of the penetration and into engagement with the needle cuffs after the foot has been drawn proximally up against the endothelial surface of the blood vessel. The cross-section of the shaft within the tissue tract can be minimized by laterally deflecting the needles as they leave the shaft, while tapered depressions within the foot can guide the advancing needles into engagement with the cuffs. The cuffs lockingly engage the needles and can be withdrawn proximally along the needle paths and through the tissue tract so as to form a loop of suture across the puncture. The articulating foot may be realigned with the shaft and withdrawn proximally through the tissue tract without dilating the tissue tract.
摘要翻译：用于缝合体腔的装置，系统和方法允许缝合位于经皮组织道远端的血管穿刺部位。在轴的远端附近的细长的铰接脚插入穿过并被致动，使得脚沿着内腔轴线延伸。脚承载缝合附着袖口，并且针从轴穿过穿透外部的血管壁前进，并且在足部被近端拉到血管的内皮表面之后与针箍接合。当针在离开轴时横向偏转针，组织道内的轴的横截面可以被最小化，而脚内的锥形凹陷可以引导前进的针与袖口接合。袖口锁定地接合针，并且可以沿着针路径并通过组织管向近端撤回，以便在穿刺部分上形成缝合线。关节脚可以与轴重新对准并且在组织管道的近侧退回，而不会扩张组织管道。

10. 发明授权

US07842047B2 Articulating suturing device and method 有权
公开(公告)号：US07842047B2
公开(公告)日：2010-11-30
申请号：US11363005
申请日：2006-02-27
申请人： D. Bruce Modesitt , Justina A. Franco , T. Daniel Gross
发明人： D. Bruce Modesitt , Justina A. Franco , T. Daniel Gross
IPC分类号： A61B17/04 , A61B17/10
CPC分类号： A61B17/0625 , A61B17/0057 , A61B17/0469 , A61B17/0482 , A61B17/0483 , A61B2017/00637 , A61B2017/00641 , A61B2017/00663 , A61B2017/00672 , A61B2017/047 , A61B2017/0472 , A61B2017/0477 , A61B2017/0496 , A61B2017/06057 , A61B2017/2927
摘要： Devices, systems, and methods for suturing of body lumens allow the suturing of vascular puncture sites located at the distal end of a percutaneous tissue tract. An elongated articulated foot near a distal end of a shaft is inserted through the penetration and actuated so that the foot extends along the lumenal axis. The foot carries suturing attachment cuffs, and needles are advanced from the shaft through the vessel wall outside of the penetration and into engagement with the needle cuffs after the foot has been drawn proximally up against the endothelial surface of the blood vessel. The cross-section of the shaft within the tissue tract can be minimized by laterally deflecting the needles as they leave the shaft, while tapered depressions within the foot can guide the advancing needles into engagement with the cuffs. The cuffs lockingly engage the needles and can be withdrawn proximally along the needle paths and through the tissue tract so as to form a loop of suture across the puncture. The articulating foot may be realigned with the shaft and withdrawn proximally through the tissue tract without dilating the tissue tract.

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